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The map label for this gene is crt [H]

Identifier: 93006340

GI number: 93006340

Start: 1860998

End: 1862242

Strand: Reverse

Name: crt [H]

Synonym: Pcryo_1514

Alternate gene names: 93006340

Gene position: 1862242-1860998 (Counterclockwise)

Preceding gene: 93006341

Following gene: 93006339

Centisome position: 60.86

GC content: 46.75

Gene sequence:

>1245_bases
ATGACAGCAGCTATAGAAGGCACACTAGAGGCGCCGGTATTATTCAGCACCGAACCGACAGATTGTGGTCACCTTATTGG
GATAATGACGTTAAATATGCCCAAATCTCTTAATGCCTTAAGCGTTGAGATGTGTCAGTTGTTATCGCAACAACTAGAGC
AGTGGCAAGGTGATGAGCAAGTAGTGGCATTGCTATTAAAAGGCGCAGGCGACAAAGCGTTTTGTGCAGGCGGTGATATT
CGTAGGTTATATGACAGTATGTCAGCAACAGCGCCTATGCCAAATCCTTATGCGACGGATTTTTTTGGTCATGAATATAG
TCTTTATCGACAAATGCACTTTTATCCCAAACCATTAATCTTGTGGGGCGATGGCATCATTATGGGCGGCGGTATGGGTT
TGATGGCAGGCTGTAGTCATCGTCTGGTCACTGAGCGTACCCGTTTTGCCATGCCTGAGATTACCATAGGCTTATTCCCT
GATGCTTCTGGCAGTTGGTTTTTGCAGCGCATGCCGGCTAAAACTGGTTTGTTCTTGGGATTGACGGGTGCGATGTGTAA
TGGTAGCGATGCATTATTGACCAACTTAGCAGAATATGGGGTTGGAAGTCAGGATTATGATGCCATCATGCAGCGCTTAA
CACAGAGCGACTGGCAAACGGCAGCTGATAATAATAAAGAGAATAAGCACAATAAAGAAAGTAACAACAGCGCCCATAGT
ATCGTGAGTCGGGCATTGGGGGCGCAGCCTGTTGCTGAATTGCCTGCTAGTAAGCTTGCACAGCATTGGTGTGCTATTCA
GCAACTAATGAACAGAGGCGGTTTGGGTGATATCGATGCGCTATTACAAAATGATGAGGCGCTCACACAACTTGATACAG
ATTTTGCTACCGACAGTTGGGCACAACGAGCCATTGCAACCTATCGACATGGCTGTCCAGTGACTGCGGCATTGACCTAT
GCGCTATATCATAAGGTGACGGATTTATCGCTAGAGCAAGTTCTGTATTTAGAAGCCAATGTCGCTGTACATTGTGCCGC
CAATCCTGACTTTAAAGAAGGCGTACGTGCGCTACTGATTGATAAAGATCGTAATCCACAGTGGTCACGCTCACTAGCAG
ACTGCTTGAGTAGCGAAGGGCAGGCGTACATACAGCAGCACTTTATCAATCCTTATGCTAAAGATGAGCATCCGTTAGGC
GATTGGCTTAGCGCTGCTGCATTGGGTAATGAAGCGGTTCGCTAA

Upstream 100 bases:

>100_bases
CATTTTTAGAGAAGCGTAAGCCTGTTTGGCAAAATAAATAAACGCCATAGAATCAAACTTAATGATACTATTTTTCTTTT
AATATTTGTAGGTCACATTT

Downstream 100 bases:

>100_bases
CCAGATATTTAGCATCTGATTTAAGCTAACTTAACTGGATTAAGTGACTAGATTAAGTGAAATTTGAAAAATTAAAACTA
ATTGCATAATCAATCATCAA

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MTAAIEGTLEAPVLFSTEPTDCGHLIGIMTLNMPKSLNALSVEMCQLLSQQLEQWQGDEQVVALLLKGAGDKAFCAGGDI
RRLYDSMSATAPMPNPYATDFFGHEYSLYRQMHFYPKPLILWGDGIIMGGGMGLMAGCSHRLVTERTRFAMPEITIGLFP
DASGSWFLQRMPAKTGLFLGLTGAMCNGSDALLTNLAEYGVGSQDYDAIMQRLTQSDWQTAADNNKENKHNKESNNSAHS
IVSRALGAQPVAELPASKLAQHWCAIQQLMNRGGLGDIDALLQNDEALTQLDTDFATDSWAQRAIATYRHGCPVTAALTY
ALYHKVTDLSLEQVLYLEANVAVHCAANPDFKEGVRALLIDKDRNPQWSRSLADCLSSEGQAYIQQHFINPYAKDEHPLG
DWLSAAALGNEAVR

Sequences:

>Translated_414_residues
MTAAIEGTLEAPVLFSTEPTDCGHLIGIMTLNMPKSLNALSVEMCQLLSQQLEQWQGDEQVVALLLKGAGDKAFCAGGDI
RRLYDSMSATAPMPNPYATDFFGHEYSLYRQMHFYPKPLILWGDGIIMGGGMGLMAGCSHRLVTERTRFAMPEITIGLFP
DASGSWFLQRMPAKTGLFLGLTGAMCNGSDALLTNLAEYGVGSQDYDAIMQRLTQSDWQTAADNNKENKHNKESNNSAHS
IVSRALGAQPVAELPASKLAQHWCAIQQLMNRGGLGDIDALLQNDEALTQLDTDFATDSWAQRAIATYRHGCPVTAALTY
ALYHKVTDLSLEQVLYLEANVAVHCAANPDFKEGVRALLIDKDRNPQWSRSLADCLSSEGQAYIQQHFINPYAKDEHPLG
DWLSAAALGNEAVR
>Mature_413_residues
TAAIEGTLEAPVLFSTEPTDCGHLIGIMTLNMPKSLNALSVEMCQLLSQQLEQWQGDEQVVALLLKGAGDKAFCAGGDIR
RLYDSMSATAPMPNPYATDFFGHEYSLYRQMHFYPKPLILWGDGIIMGGGMGLMAGCSHRLVTERTRFAMPEITIGLFPD
ASGSWFLQRMPAKTGLFLGLTGAMCNGSDALLTNLAEYGVGSQDYDAIMQRLTQSDWQTAADNNKENKHNKESNNSAHSI
VSRALGAQPVAELPASKLAQHWCAIQQLMNRGGLGDIDALLQNDEALTQLDTDFATDSWAQRAIATYRHGCPVTAALTYA
LYHKVTDLSLEQVLYLEANVAVHCAANPDFKEGVRALLIDKDRNPQWSRSLADCLSSEGQAYIQQHFINPYAKDEHPLGD
WLSAAALGNEAVR

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI37594471, Length=343, Percent_Identity=32.9446064139942, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI37594469, Length=319, Percent_Identity=31.0344827586207, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI194097323, Length=221, Percent_Identity=29.8642533936652, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1787660, Length=146, Percent_Identity=32.1917808219178, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1787659, Length=149, Percent_Identity=28.8590604026846, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI25144157, Length=363, Percent_Identity=33.3333333333333, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI25144160, Length=363, Percent_Identity=33.3333333333333, Blast_Score=179, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17554946, Length=200, Percent_Identity=30, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI25145438, Length=153, Percent_Identity=31.3725490196078, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320241, Length=380, Percent_Identity=28.1578947368421, Blast_Score=140, Evalue=3e-34,
Organism=Drosophila melanogaster, GI28571729, Length=361, Percent_Identity=34.6260387811634, Blast_Score=194, Evalue=8e-50,
Organism=Drosophila melanogaster, GI28571730, Length=361, Percent_Identity=34.6260387811634, Blast_Score=194, Evalue=9e-50,
Organism=Drosophila melanogaster, GI20129971, Length=184, Percent_Identity=31.5217391304348, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24653477, Length=184, Percent_Identity=31.5217391304348, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 45277; Mature: 45146

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAAIEGTLEAPVLFSTEPTDCGHLIGIMTLNMPKSLNALSVEMCQLLSQQLEQWQGDEQ
CCCCCCCCCCCCEEECCCCCCCHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHH
VVALLLKGAGDKAFCAGGDIRRLYDSMSATAPMPNPYATDFFGHEYSLYRQMHFYPKPLI
HHHHHHHCCCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEE
LWGDGIIMGGGMGLMAGCSHRLVTERTRFAMPEITIGLFPDASGSWFLQRMPAKTGLFLG
EECCCEEEECCCHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCCCCCCEEEE
LTGAMCNGSDALLTNLAEYGVGSQDYDAIMQRLTQSDWQTAADNNKENKHNKESNNSAHS
ECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
IVSRALGAQPVAELPASKLAQHWCAIQQLMNRGGLGDIDALLQNDEALTQLDTDFATDSW
HHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHCCCCCCHHH
AQRAIATYRHGCPVTAALTYALYHKVTDLSLEQVLYLEANVAVHCAANPDFKEGVRALLI
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHEEEEECCEEEEECCCCCHHHCCEEEEE
DKDRNPQWSRSLADCLSSEGQAYIQQHFINPYAKDEHPLGDWLSAAALGNEAVR
ECCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCHHCCC
>Mature Secondary Structure 
TAAIEGTLEAPVLFSTEPTDCGHLIGIMTLNMPKSLNALSVEMCQLLSQQLEQWQGDEQ
CCCCCCCCCCCEEECCCCCCCHHEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCHHH
VVALLLKGAGDKAFCAGGDIRRLYDSMSATAPMPNPYATDFFGHEYSLYRQMHFYPKPLI
HHHHHHHCCCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEE
LWGDGIIMGGGMGLMAGCSHRLVTERTRFAMPEITIGLFPDASGSWFLQRMPAKTGLFLG
EECCCEEEECCCHHHHCCCHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHCCCCCCEEEE
LTGAMCNGSDALLTNLAEYGVGSQDYDAIMQRLTQSDWQTAADNNKENKHNKESNNSAHS
ECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
IVSRALGAQPVAELPASKLAQHWCAIQQLMNRGGLGDIDALLQNDEALTQLDTDFATDSW
HHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHCCCCCCHHH
AQRAIATYRHGCPVTAALTYALYHKVTDLSLEQVLYLEANVAVHCAANPDFKEGVRALLI
HHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHEEEEECCEEEEECCCCCHHHCCEEEEE
DKDRNPQWSRSLADCLSSEGQAYIQQHFINPYAKDEHPLGDWLSAAALGNEAVR
ECCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]