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The map label for this gene is argF [H]

Identifier: 93006287

GI number: 93006287

Start: 1802385

End: 1803302

Strand: Direct

Name: argF [H]

Synonym: Pcryo_1461

Alternate gene names: 93006287

Gene position: 1802385-1803302 (Clockwise)

Preceding gene: 93006286

Following gene: 93006293

Centisome position: 58.9

GC content: 44.88

Gene sequence:

>918_bases
ATGAGTTTGCGCCATTTTTTGACCTTATCTGATTTAACCAAACAAGAACTAGAAAATCTTATCAAACGCGCCAGCGAATT
GCGTCATATGCAACATGCAGGCGAGATATACCAGCCCTTTGTTGGTCGTACGCTCGGTATGATATTTGAGAAATCATCCA
CCCGCACGCGTATCTCGTTTGAAACCGGCATGGGACAGTTTGGTGGTAGCGCTATCTTCTTATCGCCAAATGATACCCAA
CTTGGACGCGGTGAGCCAATTGAGGATTCCGCGCGCGTTATCTCTAGCATGGTCGATATCATTATGATTCGCACCTTTGG
TCATGAAAAAGTCGAAACCTTTGCAAAATACTCAAGCGTACCAATCATTAATGCCTTAACGGATGAATTTCATCCATGCC
AGCTATTAGCTGATATGCAAACTTACTACGAGCATCGCGGTAGTATCGAAAATAAAATCGTCACTTGGGTCGGTGATGGC
AACAATATGTGTGCATCCTACATGCAAGCTGCCAATCAGTTTGGCTTTGAGCTACGAGTAGCCGCGCCTTATGGCTTTGA
GCCTGACCCTGAGCTGATGAAACGCTTCTCACATTGCGTGAGTATCGTTGAAAACGTACAAGAAGCGGCAAAAGACTCTC
ACTTAATTGTCACTGATGTGTGGGCAAGCATGGGTCAAGAGTCTGAACAAAACACGCGTGCGCGTCGTTTTTCCTCTTAT
CAAGTGACACCATCACTGCTAGATAAAGCCGATTCTGAAGTAGTCTTTATGCACTGTTTGCCAGCGCATCGTGGTGAGGA
GATCTCTCATGATATGTTAGATGACCCACGCTCAGTGGTATGGGATGAGGCTGAAAACCGTTTACATGCGCAAAAAGCCT
TGATGGAGTTTTTGCTAAAAGACAAAATCAAAATATAG

Upstream 100 bases:

>100_bases
CTAAAAGTTTGTTGTCATTCCAGTATACGCATTGACGCGATATCATTGCCGGCTGATAACGTATCATTTTCATTGACTTT
GTTCGACTGCTAGGATTGCT

Downstream 100 bases:

>100_bases
GTACCATTTTTCAAAAGCTATTTATACAGTCATAAATATCAAAAAGGCAGAGCACATAACTTGTGCTCTGCCTTTTTTAA
TATGTGATAACCAAGTTAGT

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSLRHFLTLSDLTKQELENLIKRASELRHMQHAGEIYQPFVGRTLGMIFEKSSTRTRISFETGMGQFGGSAIFLSPNDTQ
LGRGEPIEDSARVISSMVDIIMIRTFGHEKVETFAKYSSVPIINALTDEFHPCQLLADMQTYYEHRGSIENKIVTWVGDG
NNMCASYMQAANQFGFELRVAAPYGFEPDPELMKRFSHCVSIVENVQEAAKDSHLIVTDVWASMGQESEQNTRARRFSSY
QVTPSLLDKADSEVVFMHCLPAHRGEEISHDMLDDPRSVVWDEAENRLHAQKALMEFLLKDKIKI

Sequences:

>Translated_305_residues
MSLRHFLTLSDLTKQELENLIKRASELRHMQHAGEIYQPFVGRTLGMIFEKSSTRTRISFETGMGQFGGSAIFLSPNDTQ
LGRGEPIEDSARVISSMVDIIMIRTFGHEKVETFAKYSSVPIINALTDEFHPCQLLADMQTYYEHRGSIENKIVTWVGDG
NNMCASYMQAANQFGFELRVAAPYGFEPDPELMKRFSHCVSIVENVQEAAKDSHLIVTDVWASMGQESEQNTRARRFSSY
QVTPSLLDKADSEVVFMHCLPAHRGEEISHDMLDDPRSVVWDEAENRLHAQKALMEFLLKDKIKI
>Mature_304_residues
SLRHFLTLSDLTKQELENLIKRASELRHMQHAGEIYQPFVGRTLGMIFEKSSTRTRISFETGMGQFGGSAIFLSPNDTQL
GRGEPIEDSARVISSMVDIIMIRTFGHEKVETFAKYSSVPIINALTDEFHPCQLLADMQTYYEHRGSIENKIVTWVGDGN
NMCASYMQAANQFGFELRVAAPYGFEPDPELMKRFSHCVSIVENVQEAAKDSHLIVTDVWASMGQESEQNTRARRFSSYQ
VTPSLLDKADSEVVFMHCLPAHRGEEISHDMLDDPRSVVWDEAENRLHAQKALMEFLLKDKIKI

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=306, Percent_Identity=40.1960784313725, Blast_Score=238, Evalue=5e-63,
Organism=Homo sapiens, GI18105007, Length=304, Percent_Identity=27.9605263157895, Blast_Score=108, Evalue=6e-24,
Organism=Escherichia coli, GI1790703, Length=322, Percent_Identity=36.9565217391304, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI1786469, Length=322, Percent_Identity=36.9565217391304, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI2367364, Length=309, Percent_Identity=27.831715210356, Blast_Score=85, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI193204318, Length=320, Percent_Identity=23.75, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322373, Length=323, Percent_Identity=34.3653250773994, Blast_Score=206, Evalue=5e-54,
Organism=Saccharomyces cerevisiae, GI6322331, Length=312, Percent_Identity=27.5641025641026, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24642586, Length=311, Percent_Identity=25.7234726688103, Blast_Score=89, Evalue=3e-18,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 34657; Mature: 34526

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRHFLTLSDLTKQELENLIKRASELRHMQHAGEIYQPFVGRTLGMIFEKSSTRTRISF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
ETGMGQFGGSAIFLSPNDTQLGRGEPIEDSARVISSMVDIIMIRTFGHEKVETFAKYSSV
CCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
PIINALTDEFHPCQLLADMQTYYEHRGSIENKIVTWVGDGNNMCASYMQAANQFGFELRV
CCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEE
AAPYGFEPDPELMKRFSHCVSIVENVQEAAKDSHLIVTDVWASMGQESEQNTRARRFSSY
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCCCHHHHHHHHHCCC
QVTPSLLDKADSEVVFMHCLPAHRGEEISHDMLDDPRSVVWDEAENRLHAQKALMEFLLK
CCCHHHHCCCCCCEEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DKIKI
HHCCC
>Mature Secondary Structure 
SLRHFLTLSDLTKQELENLIKRASELRHMQHAGEIYQPFVGRTLGMIFEKSSTRTRISF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
ETGMGQFGGSAIFLSPNDTQLGRGEPIEDSARVISSMVDIIMIRTFGHEKVETFAKYSSV
CCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCC
PIINALTDEFHPCQLLADMQTYYEHRGSIENKIVTWVGDGNNMCASYMQAANQFGFELRV
CCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEE
AAPYGFEPDPELMKRFSHCVSIVENVQEAAKDSHLIVTDVWASMGQESEQNTRARRFSSY
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCCCHHHHHHHHHCCC
QVTPSLLDKADSEVVFMHCLPAHRGEEISHDMLDDPRSVVWDEAENRLHAQKALMEFLLK
CCCHHHHCCCCCCEEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
DKIKI
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA