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The map label for this gene is lspA [H]

Identifier: 93006180

GI number: 93006180

Start: 1654232

End: 1654939

Strand: Direct

Name: lspA [H]

Synonym: Pcryo_1352

Alternate gene names: 93006180

Gene position: 1654232-1654939 (Clockwise)

Preceding gene: 93006179

Following gene: 93006181

Centisome position: 54.06

GC content: 38.98

Gene sequence:

>708_bases
ATGACTGAATCTACCGACAGATTAGATAGTACTAAATTGAATAGCGTTGAATCGGCTAGTACTAATATTGCTGACAATAA
AGTACCTATAGCTGTGAGTAGTACTCATCAATCAATTGACTCTAAAACCATGAATCATACGCCTAAAGCTATGTACGTAA
CTTCAGGCAACTCGATAACACCTAAAGGTAAGTTGAATAAAATGCCAAAAATGGTTGCCAATGGCAGTCGCGCTTTTATC
TGGTATTTGTTGGCGATAATGGTATTAATACTTGATCAATGGACTAAGTGGTTGGCCCAAACCAAATTAGCGTTCAATGA
CCCCGTACCGGTCATTGAACCATTTCTCAACTGGACACTCGCTTATAACTATGGGGCAGCATTTAGCTTTTTAGCCGACG
CTGGCGGTTGGCAGAAATGGTTTTTCTCAGGCTTAGCTTTTATAATGGCTATCTTTTTAACGGTTTATTTAATCAAAGCG
CCACGTGCAGCCAAGCTATTGTCCATGGGGTTAGCCTTAATGCTCGGTGGTGCGATTGGCAACTTAATCGATCGTTTAAG
AATTGGTAAAGTGGTTGACTTTATCCATGTGCATTATGCTGATGTCTGGAATTATCCTATTTTCAATGTTGCAGATATAG
GTGTCTGTGTCGGTGTCGCATTGATTATAATTGACATGATATTTTTAGAAAGTAAGCGTAATAAATAA

Upstream 100 bases:

>100_bases
AGTGGAGCAGTTTTTAAAAGTGGCGCTATTAATAGTCGTATACTAAAAACATATACGTTTAACATTGTTCATTGTATAAA
CACAGATAAAGAAAACAACT

Downstream 100 bases:

>100_bases
GCACATTGATGCCGATTATCACAAACAAAATGAACTAGCGTCGTAGTCACTCTATACGGAAAAATACTTTTTATACTTGA
GTATGTTTATAAAATGTGAA

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MTESTDRLDSTKLNSVESASTNIADNKVPIAVSSTHQSIDSKTMNHTPKAMYVTSGNSITPKGKLNKMPKMVANGSRAFI
WYLLAIMVLILDQWTKWLAQTKLAFNDPVPVIEPFLNWTLAYNYGAAFSFLADAGGWQKWFFSGLAFIMAIFLTVYLIKA
PRAAKLLSMGLALMLGGAIGNLIDRLRIGKVVDFIHVHYADVWNYPIFNVADIGVCVGVALIIIDMIFLESKRNK

Sequences:

>Translated_235_residues
MTESTDRLDSTKLNSVESASTNIADNKVPIAVSSTHQSIDSKTMNHTPKAMYVTSGNSITPKGKLNKMPKMVANGSRAFI
WYLLAIMVLILDQWTKWLAQTKLAFNDPVPVIEPFLNWTLAYNYGAAFSFLADAGGWQKWFFSGLAFIMAIFLTVYLIKA
PRAAKLLSMGLALMLGGAIGNLIDRLRIGKVVDFIHVHYADVWNYPIFNVADIGVCVGVALIIIDMIFLESKRNK
>Mature_234_residues
TESTDRLDSTKLNSVESASTNIADNKVPIAVSSTHQSIDSKTMNHTPKAMYVTSGNSITPKGKLNKMPKMVANGSRAFIW
YLLAIMVLILDQWTKWLAQTKLAFNDPVPVIEPFLNWTLAYNYGAAFSFLADAGGWQKWFFSGLAFIMAIFLTVYLIKAP
RAAKLLSMGLALMLGGAIGNLIDRLRIGKVVDFIHVHYADVWNYPIFNVADIGVCVGVALIIIDMIFLESKRNK

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=160, Percent_Identity=45.625, Blast_Score=132, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 26053; Mature: 25922

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESTDRLDSTKLNSVESASTNIADNKVPIAVSSTHQSIDSKTMNHTPKAMYVTSGNSIT
CCCCCCCCCHHHCCCHHHCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCEEEEECCCCCC
PKGKLNKMPKMVANGSRAFIWYLLAIMVLILDQWTKWLAQTKLAFNDPVPVIEPFLNWTL
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AYNYGAAFSFLADAGGWQKWFFSGLAFIMAIFLTVYLIKAPRAAKLLSMGLALMLGGAIG
EECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
NLIDRLRIGKVVDFIHVHYADVWNYPIFNVADIGVCVGVALIIIDMIFLESKRNK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TESTDRLDSTKLNSVESASTNIADNKVPIAVSSTHQSIDSKTMNHTPKAMYVTSGNSIT
CCCCCCCCHHHCCCHHHCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCEEEEECCCCCC
PKGKLNKMPKMVANGSRAFIWYLLAIMVLILDQWTKWLAQTKLAFNDPVPVIEPFLNWTL
CCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
AYNYGAAFSFLADAGGWQKWFFSGLAFIMAIFLTVYLIKAPRAAKLLSMGLALMLGGAIG
EECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
NLIDRLRIGKVVDFIHVHYADVWNYPIFNVADIGVCVGVALIIIDMIFLESKRNK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA