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The map label for this gene is glsA

Identifier: 93006158

GI number: 93006158

Start: 1627698

End: 1628618

Strand: Reverse

Name: glsA

Synonym: Pcryo_1330

Alternate gene names: 93006158

Gene position: 1628618-1627698 (Counterclockwise)

Preceding gene: 93006160

Following gene: 93006155

Centisome position: 53.22

GC content: 46.8

Gene sequence:

>921_bases
ATGCAACAGATTCTTAATGATATTGCCGCAGAGATGGCCCTTGAAACCGATCGTGGAAAAGTGGCAGATTATATCCCGCA
ACTGGCGCATGTCGATCCGAACCAGTTTGGTATTGCCGTAGCGACACCTGATGGGCAAGTATATGTAGCAGGGGATGCGA
GCACCCTATTCTCGATTCAAAGTATCTCCAAAGTATTTACCTTAACCATCGGTCTTGGCAAGTTAGGTGATGCGATTTGG
ACCCATGTTGGTCGTGAGCCATCTGGCGATCCCTTTAACTCGATCACGGTATTGGAGTTTGAATCGGGTCGACCGCGTAA
TCCATTTATCAATGCTGGTGCGATTGCTGTGGTGGATGCCATTATGATGGGACATGAGCCGAAAGAAACCTTGGGTGAAA
TTCTGCGGTTTGTACACTTTATTGCCGATGATGATTCGATCCGTTTTGACCATAAAGTGGCAGCGTCTGAAATGGATCAT
AGAGATCGAAATGCCGCCTTAGCCCACTTTATGAAGTCCTTTGGTCATATAAAGCACGATGTAGATAAGGTGCTCGGTGT
TTATTTTCATCAATGCGCGATTGCAATGAGTTGTGAGCAGTTAGCCCGTGCTGGTCTTTTTTTAGTGTCTAATGGTGTTA
ATCAACACACAGGGATACGAGTGATTAATGCACAGCAGTCTCGACGGATAAACTCCTTAATGATGATGTGCGGTCATTAC
GATGGCGCTGGTGAATTTGCCTACCGTGTCGGGCTACCGGGTAAAAGTGGTGTTGGTGGCGGTATTTTGACGATAGCGCC
AGGTAAAGGCTCAATCGCAGTCTGGTCACCAGGGCTTGATCACGTAGGAAATTCCAAACTTGGGTCAAAGGCATTAGAGC
TGCTGGTACAGAAAACGGGCTGGTCAGTTTTTTCGAATTGA

Upstream 100 bases:

>100_bases
GACCTGAATTAAAATATAATATTTACATCCTTATCACCTTTTATTCAGTTAAAATCACTATTATTCAACAACGCAGTAGA
AATACGGTTACCCAACTCAT

Downstream 100 bases:

>100_bases
AAACGATCCCTTAATGCTTTTTTAATTGATTATCAATCCAGCGAGTAATGTCGCTTTTTCGGAAAGTATTACATCCTGAT
TGTAGCGATTCTATTTTAGG

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MQQILNDIAAEMALETDRGKVADYIPQLAHVDPNQFGIAVATPDGQVYVAGDASTLFSIQSISKVFTLTIGLGKLGDAIW
THVGREPSGDPFNSITVLEFESGRPRNPFINAGAIAVVDAIMMGHEPKETLGEILRFVHFIADDDSIRFDHKVAASEMDH
RDRNAALAHFMKSFGHIKHDVDKVLGVYFHQCAIAMSCEQLARAGLFLVSNGVNQHTGIRVINAQQSRRINSLMMMCGHY
DGAGEFAYRVGLPGKSGVGGGILTIAPGKGSIAVWSPGLDHVGNSKLGSKALELLVQKTGWSVFSN

Sequences:

>Translated_306_residues
MQQILNDIAAEMALETDRGKVADYIPQLAHVDPNQFGIAVATPDGQVYVAGDASTLFSIQSISKVFTLTIGLGKLGDAIW
THVGREPSGDPFNSITVLEFESGRPRNPFINAGAIAVVDAIMMGHEPKETLGEILRFVHFIADDDSIRFDHKVAASEMDH
RDRNAALAHFMKSFGHIKHDVDKVLGVYFHQCAIAMSCEQLARAGLFLVSNGVNQHTGIRVINAQQSRRINSLMMMCGHY
DGAGEFAYRVGLPGKSGVGGGILTIAPGKGSIAVWSPGLDHVGNSKLGSKALELLVQKTGWSVFSN
>Mature_306_residues
MQQILNDIAAEMALETDRGKVADYIPQLAHVDPNQFGIAVATPDGQVYVAGDASTLFSIQSISKVFTLTIGLGKLGDAIW
THVGREPSGDPFNSITVLEFESGRPRNPFINAGAIAVVDAIMMGHEPKETLGEILRFVHFIADDDSIRFDHKVAASEMDH
RDRNAALAHFMKSFGHIKHDVDKVLGVYFHQCAIAMSCEQLARAGLFLVSNGVNQHTGIRVINAQQSRRINSLMMMCGHY
DGAGEFAYRVGLPGKSGVGGGILTIAPGKGSIAVWSPGLDHVGNSKLGSKALELLVQKTGWSVFSN

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family

Homologues:

Organism=Homo sapiens, GI156104878, Length=303, Percent_Identity=36.963696369637, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI20336214, Length=291, Percent_Identity=35.7388316151203, Blast_Score=180, Evalue=2e-45,
Organism=Escherichia coli, GI1787804, Length=304, Percent_Identity=50, Blast_Score=285, Evalue=2e-78,
Organism=Escherichia coli, GI1786693, Length=287, Percent_Identity=39.7212543554007, Blast_Score=193, Evalue=9e-51,
Organism=Caenorhabditis elegans, GI17507019, Length=304, Percent_Identity=36.8421052631579, Blast_Score=189, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17532727, Length=286, Percent_Identity=36.3636363636364, Blast_Score=181, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI193204073, Length=296, Percent_Identity=35.472972972973, Blast_Score=179, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI193204075, Length=298, Percent_Identity=35.2348993288591, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI281363241, Length=296, Percent_Identity=37.1621621621622, Blast_Score=191, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24653162, Length=296, Percent_Identity=37.1621621621622, Blast_Score=191, Evalue=5e-49,
Organism=Drosophila melanogaster, GI24653156, Length=295, Percent_Identity=36.6101694915254, Blast_Score=191, Evalue=6e-49,
Organism=Drosophila melanogaster, GI24653164, Length=296, Percent_Identity=37.1621621621622, Blast_Score=191, Evalue=6e-49,
Organism=Drosophila melanogaster, GI116008307, Length=295, Percent_Identity=36.6101694915254, Blast_Score=191, Evalue=6e-49,
Organism=Drosophila melanogaster, GI24653166, Length=296, Percent_Identity=37.1621621621622, Blast_Score=191, Evalue=7e-49,
Organism=Drosophila melanogaster, GI281363239, Length=295, Percent_Identity=36.6101694915254, Blast_Score=191, Evalue=7e-49,
Organism=Drosophila melanogaster, GI24653158, Length=295, Percent_Identity=36.6101694915254, Blast_Score=191, Evalue=7e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLSA_PSYCK (Q1QB42)

Other databases:

- EMBL:   CP000323
- RefSeq:   YP_580595.1
- ProteinModelPortal:   Q1QB42
- SMR:   Q1QB42
- STRING:   Q1QB42
- GeneID:   4034531
- GenomeReviews:   CP000323_GR
- KEGG:   pcr:Pcryo_1330
- NMPDR:   fig|335284.3.peg.1201
- eggNOG:   COG2066
- HOGENOM:   HBG512335
- OMA:   RNASIAY
- PhylomeDB:   Q1QB42
- ProtClustDB:   PRK00971
- BioCyc:   PCRY335284:PCRYO_1330-MONOMER
- HAMAP:   MF_00313
- InterPro:   IPR012338
- InterPro:   IPR015868
- Gene3D:   G3DSA:3.40.710.20
- PANTHER:   PTHR12544
- TIGRFAMs:   TIGR03814

Pfam domain/function: PF04960 Glutaminase; SSF56601 PBP_transp_fold

EC number: =3.5.1.2

Molecular weight: Translated: 32953; Mature: 32953

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQILNDIAAEMALETDRGKVADYIPQLAHVDPNQFGIAVATPDGQVYVAGDASTLFSIQ
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCEEEEECCHHHHHHHH
SISKVFTLTIGLGKLGDAIWTHVGREPSGDPFNSITVLEFESGRPRNPFINAGAIAVVDA
HHHHHHHHEECHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHH
IMMGHEPKETLGEILRFVHFIADDDSIRFDHKVAASEMDHRDRNAALAHFMKSFGHIKHD
HHHCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VDKVLGVYFHQCAIAMSCEQLARAGLFLVSNGVNQHTGIRVINAQQSRRINSLMMMCGHY
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHCCC
DGAGEFAYRVGLPGKSGVGGGILTIAPGKGSIAVWSPGLDHVGNSKLGSKALELLVQKTG
CCCCCEEEEECCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCC
WSVFSN
CHHCCC
>Mature Secondary Structure
MQQILNDIAAEMALETDRGKVADYIPQLAHVDPNQFGIAVATPDGQVYVAGDASTLFSIQ
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEECCCCEEEEECCHHHHHHHH
SISKVFTLTIGLGKLGDAIWTHVGREPSGDPFNSITVLEFESGRPRNPFINAGAIAVVDA
HHHHHHHHEECHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHH
IMMGHEPKETLGEILRFVHFIADDDSIRFDHKVAASEMDHRDRNAALAHFMKSFGHIKHD
HHHCCCCHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VDKVLGVYFHQCAIAMSCEQLARAGLFLVSNGVNQHTGIRVINAQQSRRINSLMMMCGHY
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHCCC
DGAGEFAYRVGLPGKSGVGGGILTIAPGKGSIAVWSPGLDHVGNSKLGSKALELLVQKTG
CCCCCEEEEECCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCC
WSVFSN
CHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA