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The map label for this gene is yefM [H]

Identifier: 93006136

GI number: 93006136

Start: 1596710

End: 1597048

Strand: Reverse

Name: yefM [H]

Synonym: Pcryo_1308

Alternate gene names: 93006136

Gene position: 1597048-1596710 (Counterclockwise)

Preceding gene: 93006137

Following gene: 93006135

Centisome position: 52.19

GC content: 46.02

Gene sequence:

>339_bases
ATGGAGTATGTCGTGAGAGTCATTAGTTTTTCAGAAGCCAGAAAGCACTTAAAGTCCGTCCTAGATACGGTAAACGATGA
TGCCAACGCCACTATCGTGACCCGTCGTGACGCTGATGATGCGGTTGTCATGTCGCTTGATTATTACAATAGCCTGATGG
AAACCGTCTATCTATTAAGATCTCCTGCCAATGCGGCGCACTTAGCGGAATCTATTGCCCAATATAAAGCTGGCAAGACT
GTTACGCGTGAGCTAATTGATACCGCAGAAGGCAGTGATAAAAGTGATGGTAGCAGCGATGACAATGAGCATACGAATGG
CGACGTTGAGAATGCTTGA

Upstream 100 bases:

>100_bases
ACACACTGAGCCTTCTTACTTATACCTAAGTATTAGATAGTAGCTAAATATTGAGTTTACTTAATTAATGGCGTAATATG
TACTATATATTGTACAAGTT

Downstream 100 bases:

>100_bases
ACTCAAAGGCTTTAATCAATGCAAAGGGTCTAATAATGAGTGAGCAACTAGCATGGACAGATGCTGCGTGGAAAGACTAT
CTGTACTGGCAAACACAAGA

Product: prevent-host-death protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 112; Mature: 112

Protein sequence:

>112_residues
MEYVVRVISFSEARKHLKSVLDTVNDDANATIVTRRDADDAVVMSLDYYNSLMETVYLLRSPANAAHLAESIAQYKAGKT
VTRELIDTAEGSDKSDGSSDDNEHTNGDVENA

Sequences:

>Translated_112_residues
MEYVVRVISFSEARKHLKSVLDTVNDDANATIVTRRDADDAVVMSLDYYNSLMETVYLLRSPANAAHLAESIAQYKAGKT
VTRELIDTAEGSDKSDGSSDDNEHTNGDVENA
>Mature_112_residues
MEYVVRVISFSEARKHLKSVLDTVNDDANATIVTRRDADDAVVMSLDYYNSLMETVYLLRSPANAAHLAESIAQYKAGKT
VTRELIDTAEGSDKSDGSSDDNEHTNGDVENA

Specific function: Part of a toxin-antitoxin (TA) module. Antitoxin that counteracts the effect of the YoeB mRNA interferase. YefM binds to the promoter region of the yefM-yeoB operon to repress transcription, YeoB acts as a corepressor [H]

COG id: COG2161

COG function: function code D; Antitoxin of toxin-antitoxin stability system

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the YefM antitoxin family [H]

Homologues:

Organism=Escherichia coli, GI87082026, Length=83, Percent_Identity=44.578313253012, Blast_Score=77, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006442 [H]

Pfam domain/function: PF02604 PhdYeFM [H]

EC number: NA

Molecular weight: Translated: 12284; Mature: 12284

Theoretical pI: Translated: 4.29; Mature: 4.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYVVRVISFSEARKHLKSVLDTVNDDANATIVTRRDADDAVVMSLDYYNSLMETVYLLR
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHH
SPANAAHLAESIAQYKAGKTVTRELIDTAEGSDKSDGSSDDNEHTNGDVENA
CCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEYVVRVISFSEARKHLKSVLDTVNDDANATIVTRRDADDAVVMSLDYYNSLMETVYLLR
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHH
SPANAAHLAESIAQYKAGKTVTRELIDTAEGSDKSDGSSDDNEHTNGDVENA
CCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12384590; 12704152 [H]