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The map label for this gene is lysA [H]

Identifier: 93006103

GI number: 93006103

Start: 1546309

End: 1547574

Strand: Reverse

Name: lysA [H]

Synonym: Pcryo_1275

Alternate gene names: 93006103

Gene position: 1547574-1546309 (Counterclockwise)

Preceding gene: 93006104

Following gene: 93006100

Centisome position: 50.58

GC content: 46.29

Gene sequence:

>1266_bases
ATGATGACAAACGCGACAACAACACACTTAATCGAAACCTCAGATAAGCATTCGCTTCCTCAAAAAATAATTGACTGTAT
CCATAATTATGGTGCGCAGCCGTCACCGCTCTGTGCTTACATTTATGATTTAGAAGCTCTAGAAGAGCGTATAACAACTA
TGAAGCGCTGCCTGCCTGATAACACGCAACTGTTTTATGCCATAAAGGCCAATGCTGAGCCTAAGATACTATCAACCTTG
GCAGAGCATGTAGATGGGTTTGAGGCCGCTTCTGCAGGCGAGCTAAATTGGCTACAAACCCACCAGCCAAACCATCCTAT
TATTTTTGGTGGACCGGGCAAGCTGACCTCAGACTTACAGCAAGCCATACACCAGCAAATCGATACCATTCATGTGGAGA
GTCTGGTCGAGCTGACTCGAATCCAGATCTTAAGCCAAGCCTTGCAGCTTCCCGTCCGTATATTTTTGCGGATGAATATT
GATATTGGTGATATCGGCAGCAGTAAGCTGGTCATGGGCGGCAAGCCTACCCCCTTTGGGCTAGATGAAACCCATCTCAA
GCAAGCGCTAGCTATCATCGACTCAAGCCCATTTATTGAATTTTGTGGGTTTCATTTTCACTTGATGTCGCATCAATTAT
CCGTCGAGCGCCATCTGCTATTAATGCAGCGCTATATGGAGATGGTCAAGAAGTGGCAGCACGATTATCCGTCGTTGCCC
TCAAACCTGACCATCAATGTGGGTGGCGGCATTGGTATTCACTATGATCAGCAGCCGCAGCATTTTGAGTGGGAAGTATT
CTGTCAACAGCTTGCCAGCATTTTAACGGCAAATCTGCAGTTTACGGTCAGGTTTGAGATTGGACGTTTTATCACTGCGC
CCTGTGGTTATTACGTCATGGAGGTACTGGATATCAAAAAAAATCTTGGCGAGACCTTTGTGATTGGTCATGGCGGCACG
CATCACTTTAGAACGCCCGCCGCGCAGCAGCACAATCATCCTTTTTTCATCGTGCCGCGCCGCATGAGCCACGCAATGGA
AAATAAGTTGCAAGCAAATCTGATAGAGCAAGCCGCTATCACTGGCACTAAGGCAACCCTTGTCGGTCAGCTTTGTACTC
CCAAAGACATACTGGCAAAAGATCAATGGATTGACGCGCTACATATCGGCGATTACCTAGTTTTTACCTTAGCAGGCGCT
TATGCTTGGAATATCTCTCACCAAAACTTCTTAATGCATCAGCCACCGAAAATGATTTTTTTATAA

Upstream 100 bases:

>100_bases
ATGCTTCCTTGCCCATGGCAGTCCTCTATGCTCAACGCCAATAAAGACAATAAATCTAATATAAAAACTCATAAATTATC
TGAATTAAAGGTTGCCTAAA

Downstream 100 bases:

>100_bases
AAGGATAAGGCTAATTTAATATATGAAGAAGAATTTGCGTCTTTGTTAGGCACCGTTAATAATTAAGAAAGAATGAAGCT
GGTTTAAGTGTGACAGGTTG

Product: Orn/DAP/Arg decarboxylase 2

Products: NA

Alternate protein names: DAP decarboxylase [H]

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MMTNATTTHLIETSDKHSLPQKIIDCIHNYGAQPSPLCAYIYDLEALEERITTMKRCLPDNTQLFYAIKANAEPKILSTL
AEHVDGFEAASAGELNWLQTHQPNHPIIFGGPGKLTSDLQQAIHQQIDTIHVESLVELTRIQILSQALQLPVRIFLRMNI
DIGDIGSSKLVMGGKPTPFGLDETHLKQALAIIDSSPFIEFCGFHFHLMSHQLSVERHLLLMQRYMEMVKKWQHDYPSLP
SNLTINVGGGIGIHYDQQPQHFEWEVFCQQLASILTANLQFTVRFEIGRFITAPCGYYVMEVLDIKKNLGETFVIGHGGT
HHFRTPAAQQHNHPFFIVPRRMSHAMENKLQANLIEQAAITGTKATLVGQLCTPKDILAKDQWIDALHIGDYLVFTLAGA
YAWNISHQNFLMHQPPKMIFL

Sequences:

>Translated_421_residues
MMTNATTTHLIETSDKHSLPQKIIDCIHNYGAQPSPLCAYIYDLEALEERITTMKRCLPDNTQLFYAIKANAEPKILSTL
AEHVDGFEAASAGELNWLQTHQPNHPIIFGGPGKLTSDLQQAIHQQIDTIHVESLVELTRIQILSQALQLPVRIFLRMNI
DIGDIGSSKLVMGGKPTPFGLDETHLKQALAIIDSSPFIEFCGFHFHLMSHQLSVERHLLLMQRYMEMVKKWQHDYPSLP
SNLTINVGGGIGIHYDQQPQHFEWEVFCQQLASILTANLQFTVRFEIGRFITAPCGYYVMEVLDIKKNLGETFVIGHGGT
HHFRTPAAQQHNHPFFIVPRRMSHAMENKLQANLIEQAAITGTKATLVGQLCTPKDILAKDQWIDALHIGDYLVFTLAGA
YAWNISHQNFLMHQPPKMIFL
>Mature_421_residues
MMTNATTTHLIETSDKHSLPQKIIDCIHNYGAQPSPLCAYIYDLEALEERITTMKRCLPDNTQLFYAIKANAEPKILSTL
AEHVDGFEAASAGELNWLQTHQPNHPIIFGGPGKLTSDLQQAIHQQIDTIHVESLVELTRIQILSQALQLPVRIFLRMNI
DIGDIGSSKLVMGGKPTPFGLDETHLKQALAIIDSSPFIEFCGFHFHLMSHQLSVERHLLLMQRYMEMVKKWQHDYPSLP
SNLTINVGGGIGIHYDQQPQHFEWEVFCQQLASILTANLQFTVRFEIGRFITAPCGYYVMEVLDIKKNLGETFVIGHGGT
HHFRTPAAQQHNHPFFIVPRRMSHAMENKLQANLIEQAAITGTKATLVGQLCTPKDILAKDQWIDALHIGDYLVFTLAGA
YAWNISHQNFLMHQPPKMIFL

Specific function: Lysine biosynthesis; last step. [C]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR002986
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR000183 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.20 [H]

Molecular weight: Translated: 47572; Mature: 47572

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTNATTTHLIETSDKHSLPQKIIDCIHNYGAQPSPLCAYIYDLEALEERITTMKRCLPD
CCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
NTQLFYAIKANAEPKILSTLAEHVDGFEAASAGELNWLQTHQPNHPIIFGGPGKLTSDLQ
CCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCEEECCCCCHHHHHH
QAIHQQIDTIHVESLVELTRIQILSQALQLPVRIFLRMNIDIGDIGSSKLVMGGKPTPFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCEEEECCCCCCCC
LDETHLKQALAIIDSSPFIEFCGFHFHLMSHQLSVERHLLLMQRYMEMVKKWQHDYPSLP
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SNLTINVGGGIGIHYDQQPQHFEWEVFCQQLASILTANLQFTVRFEIGRFITAPCGYYVM
CCEEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCHHHHHH
EVLDIKKNLGETFVIGHGGTHHFRTPAAQQHNHPFFIVPRRMSHAMENKLQANLIEQAAI
HHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHH
TGTKATLVGQLCTPKDILAKDQWIDALHIGDYLVFTLAGAYAWNISHQNFLMHQPPKMIF
CCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEECCCCEEC
L
C
>Mature Secondary Structure
MMTNATTTHLIETSDKHSLPQKIIDCIHNYGAQPSPLCAYIYDLEALEERITTMKRCLPD
CCCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
NTQLFYAIKANAEPKILSTLAEHVDGFEAASAGELNWLQTHQPNHPIIFGGPGKLTSDLQ
CCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCEEECCCCCHHHHHH
QAIHQQIDTIHVESLVELTRIQILSQALQLPVRIFLRMNIDIGDIGSSKLVMGGKPTPFG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCEEEECCCCCCCC
LDETHLKQALAIIDSSPFIEFCGFHFHLMSHQLSVERHLLLMQRYMEMVKKWQHDYPSLP
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SNLTINVGGGIGIHYDQQPQHFEWEVFCQQLASILTANLQFTVRFEIGRFITAPCGYYVM
CCEEEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCHHHHHH
EVLDIKKNLGETFVIGHGGTHHFRTPAAQQHNHPFFIVPRRMSHAMENKLQANLIEQAAI
HHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHH
TGTKATLVGQLCTPKDILAKDQWIDALHIGDYLVFTLAGAYAWNISHQNFLMHQPPKMIF
CCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEECCCCEEC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10688204 [H]