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The map label for this gene is ggt [H]

Identifier: 93006049

GI number: 93006049

Start: 1479917

End: 1481854

Strand: Reverse

Name: ggt [H]

Synonym: Pcryo_1221

Alternate gene names: 93006049

Gene position: 1481854-1479917 (Counterclockwise)

Preceding gene: 93006050

Following gene: 93006047

Centisome position: 48.43

GC content: 46.13

Gene sequence:

>1938_bases
ATGTCAGCTCCATATTCTTATTCTCATCAGACACAAGCGCCCACTTATAAGACTTTAAAATCTGCAACGTTAATTATTGG
CAGCACGCTATTATTTTCTGTATCTGCCCATGCGGTAGACACAAATACTGCTGTCGCCTCAAAAACCATTAATCCAACCT
CGATTAATACCAGTGCGATTAATCTAACGGTTATGAAAGAAAATCCCACGGTATTGTCTGAGACGCAGCGCGTGACACGA
GCGAAAAGTAACACGTTCACGCCTAAGGCCACGCAAGCCAAAACCGATCAAGCCATCTATTCTGTGGACGCTATCCACCA
TCCTGTTTGGGCAAAAAACGGCATGGTTGCTACCCAAGAAGCACTGGCTTCTGATATCGGCTTAAAGATTTTGAAAGATG
GTGGCAATGCCGTTGATGCTGCTGTAGCTGTTGGCTTTGCGTTAGCTGTGACATTACCGCGAGCCGGTAATATCGGCGGT
GGCGGATTTATGATGGTATATGACGCCAAACAAGGTAAAACAGTCGCACTCGATTATCGTGAAAAAGCCCCTAGTAGCGC
CTCGCGTGATATGTATCTCGATAAGGAGGGCAATGCCGTCAGTGATTTATCTCGTTATCATGGCTTAGCAGTTGGTGTGC
CGGGTACGGTCGCAGGCTTACTCAAAGCGTTAGAGGATCATGGCACCATGAGCCGCGGGCAAGTGCTGGCACCAGCGATT
GCGCTGGCTGAAAACGGTATCGAAGTCACTGCTGGATTATCAGAGTCCCTAGAAGCGTTAAGCGATCGCTTACAAAAATG
GCCAAGTACCAAAAAGATATTCTTTAAAGCCGATGGCAGCACTTATCAACCGGGTGAGCGTTTAAAACAGCCGGAGCTGG
CAAAGTCCCTTAAACTGATTGCGGCAAAAGGTAGTGATGGTTTTTATAAAGGAGAAACCGCCCGTAAATTGGTTAAAGCG
GTCAATGAAGCAGGCGGTAAAATGAGCTTGCAGGACTTGGCAAATTATCAAGCTATTGCCCGTACACCGGTCAAAGGCGA
TTATCGTGGTTATGAGATTGTCTCCATGCCACCACCGTCTTCTGGCGGTATTCATATCGTGCAGATTTTAAATATCTTAG
AAGGTTATCCGCTAAAAGACTATGGTCAAAACAGCGCGCAAACCATTCATTTAATGGCTGAAGCTATGCAGTTGGCTTAT
GCAGATCGTTCTGAATATTTGGGGGATTCTGATTTTATTGACGTACCTGCCAGCGGTTTAACTGCCCAGCCTTATGCTGA
TAAGCTACGCACGTTAATCAACCCAAATAAAGCCACGCCAGCAGCAACTATTAAGGCAAATAACCCTCTACCTTATGAGA
GTGATCAAACCACGCATTTTTCTATTGTCGATAAAGATGGCAATGCGGTAGCCAATACGTATACGCTGAACTTTTCTTAT
GGGACGGGGCTTGTTGCTGAAGGTACGGGGATACTGCTCAATAACGAGATGGATGATTTTTCTGCTAAGCCCGGTGTGCC
AAATGGTTACGGCTTAATCGGCGGCGACGCCAATGCGGTTGAAGCCAATAAACGCCCGTTATCTTCTATGAGTCCAACAA
TCGTATTTAAAGACAGCAAACCTTATATCGTCACAGGCAGTCCGGGTGGTAGCCGCATTATTACTACCGTCACGCAGGTG
ATCTCAAATGTCATTGACCATGATATGAATATCGCTGAAGCGACGCATGCGCCACGTATTCATGACCAATGGCTACCGGA
TGAGATTCGTATCGAAAAAGCACTAAATATCGATACTATTAAGAAACTGGAGTCCATGGGACATAAGGTCAGTCAGCAGT
CAGCTATGGGATCAACACAGTCTATTATGGTTACCCCAAATGGCGTGTATGGATCTTCAGATCCACGTATTGTCGATGCG
GCAGTCGTTGGTTACTGA

Upstream 100 bases:

>100_bases
CTCGCAATATTCGTTACTATTTAACCTTATCAGTTAATCTTATTGATTAATCCTATATTTTTAGCCCAATTTCTTTCATC
CTCGTAAAAAGGACTTTGCG

Downstream 100 bases:

>100_bases
TTTAACTTTTTCATGATAAATGCGTTTGGCGAAATTGGCTGGGTGACAAGCCCGTAAACTGTTTGAACTGGCGGCTAAAG
GCACTATGATCGCTATAGCC

Product: gamma-glutamyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 645; Mature: 644

Protein sequence:

>645_residues
MSAPYSYSHQTQAPTYKTLKSATLIIGSTLLFSVSAHAVDTNTAVASKTINPTSINTSAINLTVMKENPTVLSETQRVTR
AKSNTFTPKATQAKTDQAIYSVDAIHHPVWAKNGMVATQEALASDIGLKILKDGGNAVDAAVAVGFALAVTLPRAGNIGG
GGFMMVYDAKQGKTVALDYREKAPSSASRDMYLDKEGNAVSDLSRYHGLAVGVPGTVAGLLKALEDHGTMSRGQVLAPAI
ALAENGIEVTAGLSESLEALSDRLQKWPSTKKIFFKADGSTYQPGERLKQPELAKSLKLIAAKGSDGFYKGETARKLVKA
VNEAGGKMSLQDLANYQAIARTPVKGDYRGYEIVSMPPPSSGGIHIVQILNILEGYPLKDYGQNSAQTIHLMAEAMQLAY
ADRSEYLGDSDFIDVPASGLTAQPYADKLRTLINPNKATPAATIKANNPLPYESDQTTHFSIVDKDGNAVANTYTLNFSY
GTGLVAEGTGILLNNEMDDFSAKPGVPNGYGLIGGDANAVEANKRPLSSMSPTIVFKDSKPYIVTGSPGGSRIITTVTQV
ISNVIDHDMNIAEATHAPRIHDQWLPDEIRIEKALNIDTIKKLESMGHKVSQQSAMGSTQSIMVTPNGVYGSSDPRIVDA
AVVGY

Sequences:

>Translated_645_residues
MSAPYSYSHQTQAPTYKTLKSATLIIGSTLLFSVSAHAVDTNTAVASKTINPTSINTSAINLTVMKENPTVLSETQRVTR
AKSNTFTPKATQAKTDQAIYSVDAIHHPVWAKNGMVATQEALASDIGLKILKDGGNAVDAAVAVGFALAVTLPRAGNIGG
GGFMMVYDAKQGKTVALDYREKAPSSASRDMYLDKEGNAVSDLSRYHGLAVGVPGTVAGLLKALEDHGTMSRGQVLAPAI
ALAENGIEVTAGLSESLEALSDRLQKWPSTKKIFFKADGSTYQPGERLKQPELAKSLKLIAAKGSDGFYKGETARKLVKA
VNEAGGKMSLQDLANYQAIARTPVKGDYRGYEIVSMPPPSSGGIHIVQILNILEGYPLKDYGQNSAQTIHLMAEAMQLAY
ADRSEYLGDSDFIDVPASGLTAQPYADKLRTLINPNKATPAATIKANNPLPYESDQTTHFSIVDKDGNAVANTYTLNFSY
GTGLVAEGTGILLNNEMDDFSAKPGVPNGYGLIGGDANAVEANKRPLSSMSPTIVFKDSKPYIVTGSPGGSRIITTVTQV
ISNVIDHDMNIAEATHAPRIHDQWLPDEIRIEKALNIDTIKKLESMGHKVSQQSAMGSTQSIMVTPNGVYGSSDPRIVDA
AVVGY
>Mature_644_residues
SAPYSYSHQTQAPTYKTLKSATLIIGSTLLFSVSAHAVDTNTAVASKTINPTSINTSAINLTVMKENPTVLSETQRVTRA
KSNTFTPKATQAKTDQAIYSVDAIHHPVWAKNGMVATQEALASDIGLKILKDGGNAVDAAVAVGFALAVTLPRAGNIGGG
GFMMVYDAKQGKTVALDYREKAPSSASRDMYLDKEGNAVSDLSRYHGLAVGVPGTVAGLLKALEDHGTMSRGQVLAPAIA
LAENGIEVTAGLSESLEALSDRLQKWPSTKKIFFKADGSTYQPGERLKQPELAKSLKLIAAKGSDGFYKGETARKLVKAV
NEAGGKMSLQDLANYQAIARTPVKGDYRGYEIVSMPPPSSGGIHIVQILNILEGYPLKDYGQNSAQTIHLMAEAMQLAYA
DRSEYLGDSDFIDVPASGLTAQPYADKLRTLINPNKATPAATIKANNPLPYESDQTTHFSIVDKDGNAVANTYTLNFSYG
TGLVAEGTGILLNNEMDDFSAKPGVPNGYGLIGGDANAVEANKRPLSSMSPTIVFKDSKPYIVTGSPGGSRIITTVTQVI
SNVIDHDMNIAEATHAPRIHDQWLPDEIRIEKALNIDTIKKLESMGHKVSQQSAMGSTQSIMVTPNGVYGSSDPRIVDAA
VVGY

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=532, Percent_Identity=33.2706766917293, Blast_Score=259, Evalue=5e-69,
Organism=Homo sapiens, GI73915090, Length=532, Percent_Identity=33.2706766917293, Blast_Score=259, Evalue=5e-69,
Organism=Homo sapiens, GI73915096, Length=532, Percent_Identity=33.2706766917293, Blast_Score=259, Evalue=5e-69,
Organism=Homo sapiens, GI73915094, Length=532, Percent_Identity=33.2706766917293, Blast_Score=259, Evalue=5e-69,
Organism=Homo sapiens, GI113429324, Length=541, Percent_Identity=32.1626617375231, Blast_Score=239, Evalue=6e-63,
Organism=Homo sapiens, GI113429326, Length=545, Percent_Identity=31.5596330275229, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI109148539, Length=551, Percent_Identity=31.9419237749546, Blast_Score=213, Evalue=7e-55,
Organism=Homo sapiens, GI153266885, Length=491, Percent_Identity=28.3095723014257, Blast_Score=159, Evalue=8e-39,
Organism=Homo sapiens, GI153266901, Length=492, Percent_Identity=28.2520325203252, Blast_Score=159, Evalue=9e-39,
Organism=Homo sapiens, GI153266907, Length=483, Percent_Identity=26.7080745341615, Blast_Score=140, Evalue=5e-33,
Organism=Homo sapiens, GI30581157, Length=220, Percent_Identity=32.7272727272727, Blast_Score=111, Evalue=3e-24,
Organism=Homo sapiens, GI30581155, Length=220, Percent_Identity=32.7272727272727, Blast_Score=111, Evalue=3e-24,
Organism=Homo sapiens, GI218505805, Length=218, Percent_Identity=30.7339449541284, Blast_Score=98, Evalue=3e-20,
Organism=Homo sapiens, GI310124095, Length=220, Percent_Identity=29.5454545454545, Blast_Score=84, Evalue=4e-16,
Organism=Escherichia coli, GI1789856, Length=543, Percent_Identity=58.195211786372, Blast_Score=625, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI212646519, Length=540, Percent_Identity=34.0740740740741, Blast_Score=265, Evalue=6e-71,
Organism=Caenorhabditis elegans, GI72000294, Length=540, Percent_Identity=34.0740740740741, Blast_Score=264, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI17506189, Length=536, Percent_Identity=32.8358208955224, Blast_Score=250, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI17542894, Length=511, Percent_Identity=31.8982387475538, Blast_Score=219, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI193208245, Length=509, Percent_Identity=29.6660117878193, Blast_Score=212, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI193208247, Length=509, Percent_Identity=29.6660117878193, Blast_Score=211, Evalue=7e-55,
Organism=Caenorhabditis elegans, GI17564448, Length=433, Percent_Identity=26.3279445727483, Blast_Score=93, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI72001497, Length=234, Percent_Identity=27.3504273504274, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI72001495, Length=247, Percent_Identity=26.7206477732794, Blast_Score=82, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6323330, Length=516, Percent_Identity=31.0077519379845, Blast_Score=174, Evalue=5e-44,
Organism=Drosophila melanogaster, GI45551474, Length=538, Percent_Identity=31.4126394052045, Blast_Score=229, Evalue=4e-60,
Organism=Drosophila melanogaster, GI24642670, Length=538, Percent_Identity=31.4126394052045, Blast_Score=229, Evalue=6e-60,
Organism=Drosophila melanogaster, GI24642666, Length=538, Percent_Identity=31.4126394052045, Blast_Score=229, Evalue=6e-60,
Organism=Drosophila melanogaster, GI161077880, Length=538, Percent_Identity=31.5985130111524, Blast_Score=229, Evalue=7e-60,
Organism=Drosophila melanogaster, GI161077878, Length=538, Percent_Identity=31.5985130111524, Blast_Score=228, Evalue=1e-59,
Organism=Drosophila melanogaster, GI18859893, Length=513, Percent_Identity=30.4093567251462, Blast_Score=219, Evalue=3e-57,
Organism=Drosophila melanogaster, GI161077496, Length=541, Percent_Identity=29.5748613678373, Blast_Score=212, Evalue=8e-55,
Organism=Drosophila melanogaster, GI18859741, Length=539, Percent_Identity=26.7161410018553, Blast_Score=176, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 68557; Mature: 68426

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS00462 G_GLU_TRANSPEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPYSYSHQTQAPTYKTLKSATLIIGSTLLFSVSAHAVDTNTAVASKTINPTSINTSAI
CCCCCCCCCCCCCCHHHHHHHHHHEEEHHHHHEEEHHEECCCCHHHCCCCCCCCCCCEEE
NLTVMKENPTVLSETQRVTRAKSNTFTPKATQAKTDQAIYSVDAIHHPVWAKNGMVATQE
EEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEHHHHCCCCCCCCCCEEHHH
ALASDIGLKILKDGGNAVDAAVAVGFALAVTLPRAGNIGGGGFMMVYDAKQGKTVALDYR
HHHHHCCEEEEECCCCHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCCCCEEEEECH
EKAPSSASRDMYLDKEGNAVSDLSRYHGLAVGVPGTVAGLLKALEDHGTMSRGQVLAPAI
HCCCCCCCCCEEECCCCCHHHHHHHHCCEEEECCHHHHHHHHHHHHCCCCCCCCCHHHHH
ALAENGIEVTAGLSESLEALSDRLQKWPSTKKIFFKADGSTYQPGERLKQPELAKSLKLI
HHHCCCCEEEECHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHCCCCHHHHHEEEE
AAKGSDGFYKGETARKLVKAVNEAGGKMSLQDLANYQAIARTPVKGDYRGYEIVSMPPPS
EECCCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHCCHHHHCCCCCCCCCCEEEEECCCCC
SGGIHIVQILNILEGYPLKDYGQNSAQTIHLMAEAMQLAYADRSEYLGDSDFIDVPASGL
CCCEEHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCEEECCCCCC
TAQPYADKLRTLINPNKATPAATIKANNPLPYESDQTTHFSIVDKDGNAVANTYTLNFSY
CCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCEEEEEEEEEEEC
GTGLVAEGTGILLNNEMDDFSAKPGVPNGYGLIGGDANAVEANKRPLSSMSPTIVFKDSK
CCCEEECCCEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEECCC
PYIVTGSPGGSRIITTVTQVISNVIDHDMNIAEATHAPRIHDQWLPDEIRIEKALNIDTI
CEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCHHHHHHHHCCHHHH
KKLESMGHKVSQQSAMGSTQSIMVTPNGVYGSSDPRIVDAAVVGY
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
SAPYSYSHQTQAPTYKTLKSATLIIGSTLLFSVSAHAVDTNTAVASKTINPTSINTSAI
CCCCCCCCCCCCCHHHHHHHHHHEEEHHHHHEEEHHEECCCCHHHCCCCCCCCCCCEEE
NLTVMKENPTVLSETQRVTRAKSNTFTPKATQAKTDQAIYSVDAIHHPVWAKNGMVATQE
EEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHEEHHHHCCCCCCCCCCEEHHH
ALASDIGLKILKDGGNAVDAAVAVGFALAVTLPRAGNIGGGGFMMVYDAKQGKTVALDYR
HHHHHCCEEEEECCCCHHHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCCCCEEEEECH
EKAPSSASRDMYLDKEGNAVSDLSRYHGLAVGVPGTVAGLLKALEDHGTMSRGQVLAPAI
HCCCCCCCCCEEECCCCCHHHHHHHHCCEEEECCHHHHHHHHHHHHCCCCCCCCCHHHHH
ALAENGIEVTAGLSESLEALSDRLQKWPSTKKIFFKADGSTYQPGERLKQPELAKSLKLI
HHHCCCCEEEECHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHCCCCHHHHHEEEE
AAKGSDGFYKGETARKLVKAVNEAGGKMSLQDLANYQAIARTPVKGDYRGYEIVSMPPPS
EECCCCCCCCCHHHHHHHHHHHHCCCCEEHHHHHCCHHHHCCCCCCCCCCEEEEECCCCC
SGGIHIVQILNILEGYPLKDYGQNSAQTIHLMAEAMQLAYADRSEYLGDSDFIDVPASGL
CCCEEHHHHHHHHCCCCCHHCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCEEECCCCCC
TAQPYADKLRTLINPNKATPAATIKANNPLPYESDQTTHFSIVDKDGNAVANTYTLNFSY
CCCHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCEEEEEEECCCCEEEEEEEEEEEC
GTGLVAEGTGILLNNEMDDFSAKPGVPNGYGLIGGDANAVEANKRPLSSMSPTIVFKDSK
CCCEEECCCEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCEEEEECCC
PYIVTGSPGGSRIITTVTQVISNVIDHDMNIAEATHAPRIHDQWLPDEIRIEKALNIDTI
CEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCHHHHHHHHCCHHHH
KKLESMGHKVSQQSAMGSTQSIMVTPNGVYGSSDPRIVDAAVVGY
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2570061; 9278503; 8041620; 1360205 [H]