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The map label for this gene is hisC1 [H]

Identifier: 93006033

GI number: 93006033

Start: 1459504

End: 1460646

Strand: Direct

Name: hisC1 [H]

Synonym: Pcryo_1205

Alternate gene names: 93006033

Gene position: 1459504-1460646 (Clockwise)

Preceding gene: 93006032

Following gene: 93006034

Centisome position: 47.7

GC content: 44.97

Gene sequence:

>1143_bases
ATGCAGTCTGCGCAATCGACAGAGTCAAATTTATTACCGCTCGTACCTGCTTACGAGAGTGTTTTGGCGTTGGCACCGTA
TCAAACTGGCAAGCCTATTGAAGAGCTAACGCGAGAGTATGGCGTCTCAGATGTGGTAAAAATTGCCAGTAATGAGAATC
CGATCGGCTGCTCACCGCACGTTACGCTAGCGATTACTGAACAGCTAGGTCAGCTGTCACGTTATCCTGATGGCAATGGT
TATTATCTAAAGCAAGCATTGGCTGATTTTAATGATGTCAATGCTGATCAGATTACTTTGGGCAATGGCTCTGATGATTT
GCTCGATATCTTGGCGCGTAGTTTTGTAGGTGCAGATGATGCAATCGTTTATAGTCAGTATGCCTTTGTGGTCTATTCGA
TGCTCGCTAAAATGCAGGGTGCTATGGATATTGAAGTGCCTGCTCAGCGCTTTGGTCATGACCTAAAAGCCATGAGCCAA
GCGGTTCAGGATAACTCTAATACCAAAATCGTCTTTATCGCCAATCCGAACAATCCAACCGGTACGCAGCTTGAACATGC
TGAGCTGAGAGAGTTTGTCGCTAGTGTGCCAAGCTCAGTACTGGTGGTGTTAGATGAAGCTTATATTGAATATAGCCCTG
AGAGCAATAATCGGGCGCTGTTAGATGAATTTGATAATGTGGTTATTGTTCGCACCTTTTCTAAAGCCTATGGGCTGGCA
GGTCTGCGTGTTGGCTATGCGTTAAGCTCGGTAGCTGTGGCAGATTTACTCAATCGCATTCGTCAGCCATTTAATGTGAG
CCGCATTGGACTGGCGGCAGCGGCAGCGGCACTTGCGGATCAAGACTTTATTGAAAAAACTCGTCTAATGAACAACGAGC
AGATGCGCTGGTTAGAAAAACAGTTTGATGCACTGGGACTGGGCTTTATAAAGTCACATGCCAACTTTATTATGGTCGAA
ATCGAAGTTGAAATGGAAGATACGAACGCTGCTGTTATTTATCAGGCATTGCTTGAGCAAGGCGTTATTGTGCGACAACT
AGAGGTTTATGGTTTGCATAATTGGCTGCGTATTAGTGTAGGGGTCGCAGAAGATAATATGCGTCTAATTGATACTTTGC
GCTCTATTTTGACCGATGATTAA

Upstream 100 bases:

>100_bases
CCGCAAGCGTTTATAAATTGCCTTGTCATAAATAGCGGTCACCAGTGACATTAATGGGCTTAGCCAATGATAGGTGCGTT
ATCACATCTAAGGATTAATC

Downstream 100 bases:

>100_bases
ATCAATAACTAATAAGTAATTTAATAAGCCACCTAATAATTAAAACAATATGCAAAAAATAAATCACGCCGTAAATCTTC
AAACAGCAACTAAACTGACT

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase 1 [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MQSAQSTESNLLPLVPAYESVLALAPYQTGKPIEELTREYGVSDVVKIASNENPIGCSPHVTLAITEQLGQLSRYPDGNG
YYLKQALADFNDVNADQITLGNGSDDLLDILARSFVGADDAIVYSQYAFVVYSMLAKMQGAMDIEVPAQRFGHDLKAMSQ
AVQDNSNTKIVFIANPNNPTGTQLEHAELREFVASVPSSVLVVLDEAYIEYSPESNNRALLDEFDNVVIVRTFSKAYGLA
GLRVGYALSSVAVADLLNRIRQPFNVSRIGLAAAAAALADQDFIEKTRLMNNEQMRWLEKQFDALGLGFIKSHANFIMVE
IEVEMEDTNAAVIYQALLEQGVIVRQLEVYGLHNWLRISVGVAEDNMRLIDTLRSILTDD

Sequences:

>Translated_380_residues
MQSAQSTESNLLPLVPAYESVLALAPYQTGKPIEELTREYGVSDVVKIASNENPIGCSPHVTLAITEQLGQLSRYPDGNG
YYLKQALADFNDVNADQITLGNGSDDLLDILARSFVGADDAIVYSQYAFVVYSMLAKMQGAMDIEVPAQRFGHDLKAMSQ
AVQDNSNTKIVFIANPNNPTGTQLEHAELREFVASVPSSVLVVLDEAYIEYSPESNNRALLDEFDNVVIVRTFSKAYGLA
GLRVGYALSSVAVADLLNRIRQPFNVSRIGLAAAAAALADQDFIEKTRLMNNEQMRWLEKQFDALGLGFIKSHANFIMVE
IEVEMEDTNAAVIYQALLEQGVIVRQLEVYGLHNWLRISVGVAEDNMRLIDTLRSILTDD
>Mature_380_residues
MQSAQSTESNLLPLVPAYESVLALAPYQTGKPIEELTREYGVSDVVKIASNENPIGCSPHVTLAITEQLGQLSRYPDGNG
YYLKQALADFNDVNADQITLGNGSDDLLDILARSFVGADDAIVYSQYAFVVYSMLAKMQGAMDIEVPAQRFGHDLKAMSQ
AVQDNSNTKIVFIANPNNPTGTQLEHAELREFVASVPSSVLVVLDEAYIEYSPESNNRALLDEFDNVVIVRTFSKAYGLA
GLRVGYALSSVAVADLLNRIRQPFNVSRIGLAAAAAALADQDFIEKTRLMNNEQMRWLEKQFDALGLGFIKSHANFIMVE
IEVEMEDTNAAVIYQALLEQGVIVRQLEVYGLHNWLRISVGVAEDNMRLIDTLRSILTDD

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=374, Percent_Identity=29.4117647058824, Blast_Score=150, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6322075, Length=359, Percent_Identity=29.5264623955432, Blast_Score=132, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 41862; Mature: 41862

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSAQSTESNLLPLVPAYESVLALAPYQTGKPIEELTREYGVSDVVKIASNENPIGCSPH
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHCCCCCCCCCCC
VTLAITEQLGQLSRYPDGNGYYLKQALADFNDVNADQITLGNGSDDLLDILARSFVGADD
EEEEEHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCC
AIVYSQYAFVVYSMLAKMQGAMDIEVPAQRFGHDLKAMSQAVQDNSNTKIVFIANPNNPT
HHHHHHHHHHHHHHHHHHCCCCEEECCHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCC
GTQLEHAELREFVASVPSSVLVVLDEAYIEYSPESNNRALLDEFDNVVIVRTFSKAYGLA
CCCCCHHHHHHHHHHCCCCEEEEEEHHHEEECCCCCCCCHHHCCCCEEEEEEEHHHHCCC
GLRVGYALSSVAVADLLNRIRQPFNVSRIGLAAAAAALADQDFIEKTRLMNNEQMRWLEK
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
QFDALGLGFIKSHANFIMVEIEVEMEDTNAAVIYQALLEQGVIVRQLEVYGLHNWLRISV
HHHHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHCCHHEEHHHHHCCCCEEEEEE
GVAEDNMRLIDTLRSILTDD
EECCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQSAQSTESNLLPLVPAYESVLALAPYQTGKPIEELTREYGVSDVVKIASNENPIGCSPH
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCHHHHHHHHCCCCCCCCCCC
VTLAITEQLGQLSRYPDGNGYYLKQALADFNDVNADQITLGNGSDDLLDILARSFVGADD
EEEEEHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCC
AIVYSQYAFVVYSMLAKMQGAMDIEVPAQRFGHDLKAMSQAVQDNSNTKIVFIANPNNPT
HHHHHHHHHHHHHHHHHHCCCCEEECCHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCC
GTQLEHAELREFVASVPSSVLVVLDEAYIEYSPESNNRALLDEFDNVVIVRTFSKAYGLA
CCCCCHHHHHHHHHHCCCCEEEEEEHHHEEECCCCCCCCHHHCCCCEEEEEEEHHHHCCC
GLRVGYALSSVAVADLLNRIRQPFNVSRIGLAAAAAALADQDFIEKTRLMNNEQMRWLEK
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
QFDALGLGFIKSHANFIMVEIEVEMEDTNAAVIYQALLEQGVIVRQLEVYGLHNWLRISV
HHHHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHCCHHEEHHHHHCCCCEEEEEE
GVAEDNMRLIDTLRSILTDD
EECCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA