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The map label for this gene is pheA [H]

Identifier: 93006032

GI number: 93006032

Start: 1458182

End: 1459363

Strand: Direct

Name: pheA [H]

Synonym: Pcryo_1204

Alternate gene names: 93006032

Gene position: 1458182-1459363 (Clockwise)

Preceding gene: 93006029

Following gene: 93006033

Centisome position: 47.65

GC content: 46.02

Gene sequence:

>1182_bases
ATGAGTGAGCAGTCACCAGAACAAAACAATGATAATCTAAACCAAACCACCGCAAGCATCAGTACTACCGCAACGGATAA
AGAGTTTTTGAATACATTGCGCGGCAGTATCGATGCGGTAGACTGCGAAATTCAGACGCTGATTAACAATCGTGCCAAAT
TGGCTCAGCAAGTGGCGAGCGTGAAAAAGAACCACATTGCCAATGATTCTGCTGCTGAAAATGCCAACCCTATCTTTTAC
CGTCCAGAGCGTGAGGCGCAAGTGCTAAAAGCCGTCATGGAGCGTAATGAAGGACCTATCGCCGATGAAAAAATGGCACG
CTTGTTTCGAGAGATTATGTCGGTATGCCTTGATTTAGAAGCGCCGCAGCGCATTGCGTTTTTGGGTCCACTGGGCACTT
TTACTCATGCGGCTGCCTTAAAGCACTTTGGTAAAGCGGCGGATACTGTACCGCTGAATACCATCACTGATGTGTTTCGT
GAAGTCGAAGCGGGCACCGCAATGTATGGTGTCGTGCCCGTTGAAAACTCATCTGAAGGCGTAGTCAACCATACGCTAGA
TGGCTTTTTATCTTCTACACTAAAGATAATTGGTGAAGTCGAGCTGCCGATTCATCAAAACTTTTTGGTCGCTGAACATA
CCAAACTTGATGGGTTAAGCCGTATTTACTCGCACCAGCAATCATTGGCGCAGTGTCGTCATTGGCTTGATGTGAATTAT
CCCAATGTCGAGCGTGTTGCGGTATCGAGTAATGGTGAAGCGGCACGTCGCTTGAAGAATGAGTGGCATTCGGCAGCAAT
TGCGGGTGACGTGGCAGCAGCAGAATATGATTTGCATAAGCTATATTCAAATATCGAAGACAATCCAAGCAATACGACCC
GTTTCTTGATTATTGGTCATGAAGCAATTGCACCATCAGGTCAAGATAAAACCTCGATTATGGTATCAGCGCATGACAAA
GCGGGCGCTCTGATCGAAATCTTAAAACCTTTGTCGTATCATGGCGTGTCTATGACCAGCATTGAAACGCGCCCTGAGCG
TCCTAATAAATGGGCTTACGTCTTCTTTATTGATATGAATGGGCACATTGAAGACCCAAATGTGAGCGCTGCTATCGCTG
ATATTCGCCCATTGGTCAAAGACTTACGTGTATTAGGCTCTTATCCAAAAGCGGTACTATAA

Upstream 100 bases:

>100_bases
TTCTTTAAAAAGTCTTCATGTCTTTTAACGAAGTATTTATGGTCATCATTGACAAGTATTTATACCTAACAGTAATAAAA
TCTAAAAAGGATGGGCGGTA

Downstream 100 bases:

>100_bases
ACTTACTGGTTTCTATGAGTCATTGTTTTATTAGTATTGGCCGCAAGCGTTTATAAATTGCCTTGTCATAAATAGCGGTC
ACCAGTGACATTAATGGGCT

Product: chorismate mutase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MSEQSPEQNNDNLNQTTASISTTATDKEFLNTLRGSIDAVDCEIQTLINNRAKLAQQVASVKKNHIANDSAAENANPIFY
RPEREAQVLKAVMERNEGPIADEKMARLFREIMSVCLDLEAPQRIAFLGPLGTFTHAAALKHFGKAADTVPLNTITDVFR
EVEAGTAMYGVVPVENSSEGVVNHTLDGFLSSTLKIIGEVELPIHQNFLVAEHTKLDGLSRIYSHQQSLAQCRHWLDVNY
PNVERVAVSSNGEAARRLKNEWHSAAIAGDVAAAEYDLHKLYSNIEDNPSNTTRFLIIGHEAIAPSGQDKTSIMVSAHDK
AGALIEILKPLSYHGVSMTSIETRPERPNKWAYVFFIDMNGHIEDPNVSAAIADIRPLVKDLRVLGSYPKAVL

Sequences:

>Translated_393_residues
MSEQSPEQNNDNLNQTTASISTTATDKEFLNTLRGSIDAVDCEIQTLINNRAKLAQQVASVKKNHIANDSAAENANPIFY
RPEREAQVLKAVMERNEGPIADEKMARLFREIMSVCLDLEAPQRIAFLGPLGTFTHAAALKHFGKAADTVPLNTITDVFR
EVEAGTAMYGVVPVENSSEGVVNHTLDGFLSSTLKIIGEVELPIHQNFLVAEHTKLDGLSRIYSHQQSLAQCRHWLDVNY
PNVERVAVSSNGEAARRLKNEWHSAAIAGDVAAAEYDLHKLYSNIEDNPSNTTRFLIIGHEAIAPSGQDKTSIMVSAHDK
AGALIEILKPLSYHGVSMTSIETRPERPNKWAYVFFIDMNGHIEDPNVSAAIADIRPLVKDLRVLGSYPKAVL
>Mature_392_residues
SEQSPEQNNDNLNQTTASISTTATDKEFLNTLRGSIDAVDCEIQTLINNRAKLAQQVASVKKNHIANDSAAENANPIFYR
PEREAQVLKAVMERNEGPIADEKMARLFREIMSVCLDLEAPQRIAFLGPLGTFTHAAALKHFGKAADTVPLNTITDVFRE
VEAGTAMYGVVPVENSSEGVVNHTLDGFLSSTLKIIGEVELPIHQNFLVAEHTKLDGLSRIYSHQQSLAQCRHWLDVNYP
NVERVAVSSNGEAARRLKNEWHSAAIAGDVAAAEYDLHKLYSNIEDNPSNTTRFLIIGHEAIAPSGQDKTSIMVSAHDKA
GALIEILKPLSYHGVSMTSIETRPERPNKWAYVFFIDMNGHIEDPNVSAAIADIRPLVKDLRVLGSYPKAVL

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=391, Percent_Identity=29.4117647058824, Blast_Score=159, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6324013, Length=326, Percent_Identity=27.9141104294479, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 43245; Mature: 43114

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00857 PREPHENATE_DEHYDR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQSPEQNNDNLNQTTASISTTATDKEFLNTLRGSIDAVDCEIQTLINNRAKLAQQVAS
CCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
VKKNHIANDSAAENANPIFYRPEREAQVLKAVMERNEGPIADEKMARLFREIMSVCLDLE
HHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
APQRIAFLGPLGTFTHAAALKHFGKAADTVPLNTITDVFREVEAGTAMYGVVPVENSSEG
CCCEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCC
VVNHTLDGFLSSTLKIIGEVELPIHQNFLVAEHTKLDGLSRIYSHQQSLAQCRHWLDVNY
CHHHHHHHHHHHHHHHHHCEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PNVERVAVSSNGEAARRLKNEWHSAAIAGDVAAAEYDLHKLYSNIEDNPSNTTRFLIIGH
CCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEC
EAIAPSGQDKTSIMVSAHDKAGALIEILKPLSYHGVSMTSIETRPERPNKWAYVFFIDMN
HHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEEEEECC
GHIEDPNVSAAIADIRPLVKDLRVLGSYPKAVL
CEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SEQSPEQNNDNLNQTTASISTTATDKEFLNTLRGSIDAVDCEIQTLINNRAKLAQQVAS
CCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
VKKNHIANDSAAENANPIFYRPEREAQVLKAVMERNEGPIADEKMARLFREIMSVCLDLE
HHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCC
APQRIAFLGPLGTFTHAAALKHFGKAADTVPLNTITDVFREVEAGTAMYGVVPVENSSEG
CCCEEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCC
VVNHTLDGFLSSTLKIIGEVELPIHQNFLVAEHTKLDGLSRIYSHQQSLAQCRHWLDVNY
CHHHHHHHHHHHHHHHHHCEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCC
PNVERVAVSSNGEAARRLKNEWHSAAIAGDVAAAEYDLHKLYSNIEDNPSNTTRFLIIGH
CCCEEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEEC
EAIAPSGQDKTSIMVSAHDKAGALIEILKPLSYHGVSMTSIETRPERPNKWAYVFFIDMN
HHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEEEEECC
GHIEDPNVSAAIADIRPLVKDLRVLGSYPKAVL
CEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]