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The map label for this gene is cbl [H]

Identifier: 93005983

GI number: 93005983

Start: 1399632

End: 1400561

Strand: Reverse

Name: cbl [H]

Synonym: Pcryo_1155

Alternate gene names: 93005983

Gene position: 1400561-1399632 (Counterclockwise)

Preceding gene: 93005989

Following gene: 93005982

Centisome position: 45.77

GC content: 46.02

Gene sequence:

>930_bases
ATGGCAATCGACGTAGTGGTCAATCAGCGGCATCTGCAAATTCAACTCAAACAGTTGGAGACAGTGTGGCATACCGTAAT
CAATGGCTATAATTTAAGTCAGGCGGCGACGGTACTGCATACCAGCCAATCAAGTCTTTCAAAGCATATCGCAGCACTTG
AGAATCAGCTCAAAACCGAAGTGTTCGTGCGCCAAGGCAAACGTTTAACGGGGCTTACGACAATGGGTACGGCGCTCATG
CCGCATATTGAGTCTATCTTTACCGAAATCCGTACGATTGAAAACCTCAGCCTCGACTTTAACAATCCAAATGTCGGTAC
ATTGACAATTGCCACGACTCATACTCAGGCACGTTATGTCTTACCAGAAGTCGTGAAAGAATTTAAAGAGCGTTTTCCTA
AGGTTAATCTCATTCTACAACAGGCAGATCCTGAAACCATCGCACAGATGGTGATACGTGGGCAGGCCGATATTGGTATT
GCAACCGAGTCCTTGCTACATAACAACTATCTGCGCTGCTATCGTTATTACGACTGGACGCATCGTGTCATCGTGCCAAG
CGATCATGAATTGGCAGGACTAGAATCTATCGATTTACCAACTCTCGCCAGCTATCCAATCGTAACTTATCACGGTGGTT
TTACGGGACGCGGCGCCATTGACAAGACTTTTAGCGATGCCGGTCTTGAGCCAGATATCGTATTGGCAGCACTTGATGCT
GATGTGATTAGTACCTATGTTGGACTTGGCTTAGGGATTGGTATTATTGCAGAAATGGCATTTGAGCCAAGTCATTATCA
GAATCTAACCGCCATTCCAGTCGACCATTTTGGACGTTTTACCAGTTGGATGGCAGTACGTGATGATGCAGAAATCCGCC
AGTATGGACGGGCGTTTATGGAGCTGTGTCAAAAACAGTTCAGTCAGTAA

Upstream 100 bases:

>100_bases
CAAGAATAATAGCTTTGATTTACACTACACGCTTGTTATGTTTTTTGGGCGTTTTAACTTTTATAAAGACGACTGACTCT
TTATATAATGGGATTAACTT

Downstream 100 bases:

>100_bases
TGACTGCTGTTTTCACTAATACGTGTAGCTATAGTCAATCCACTATCAATCAAACACAGTGCTACTGGTATAAGTTTTGC
GCCGCCTCTGTCTGCGCAGG

Product: transcriptional regulator CysB-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAIDVVVNQRHLQIQLKQLETVWHTVINGYNLSQAATVLHTSQSSLSKHIAALENQLKTEVFVRQGKRLTGLTTMGTALM
PHIESIFTEIRTIENLSLDFNNPNVGTLTIATTHTQARYVLPEVVKEFKERFPKVNLILQQADPETIAQMVIRGQADIGI
ATESLLHNNYLRCYRYYDWTHRVIVPSDHELAGLESIDLPTLASYPIVTYHGGFTGRGAIDKTFSDAGLEPDIVLAALDA
DVISTYVGLGLGIGIIAEMAFEPSHYQNLTAIPVDHFGRFTSWMAVRDDAEIRQYGRAFMELCQKQFSQ

Sequences:

>Translated_309_residues
MAIDVVVNQRHLQIQLKQLETVWHTVINGYNLSQAATVLHTSQSSLSKHIAALENQLKTEVFVRQGKRLTGLTTMGTALM
PHIESIFTEIRTIENLSLDFNNPNVGTLTIATTHTQARYVLPEVVKEFKERFPKVNLILQQADPETIAQMVIRGQADIGI
ATESLLHNNYLRCYRYYDWTHRVIVPSDHELAGLESIDLPTLASYPIVTYHGGFTGRGAIDKTFSDAGLEPDIVLAALDA
DVISTYVGLGLGIGIIAEMAFEPSHYQNLTAIPVDHFGRFTSWMAVRDDAEIRQYGRAFMELCQKQFSQ
>Mature_308_residues
AIDVVVNQRHLQIQLKQLETVWHTVINGYNLSQAATVLHTSQSSLSKHIAALENQLKTEVFVRQGKRLTGLTTMGTALMP
HIESIFTEIRTIENLSLDFNNPNVGTLTIATTHTQARYVLPEVVKEFKERFPKVNLILQQADPETIAQMVIRGQADIGIA
TESLLHNNYLRCYRYYDWTHRVIVPSDHELAGLESIDLPTLASYPIVTYHGGFTGRGAIDKTFSDAGLEPDIVLAALDAD
VISTYVGLGLGIGIIAEMAFEPSHYQNLTAIPVDHFGRFTSWMAVRDDAEIRQYGRAFMELCQKQFSQ

Specific function: May be an accessory regulatory protein within the cys regulon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788296, Length=296, Percent_Identity=43.5810810810811, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1787530, Length=289, Percent_Identity=40.8304498269896, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI157672245, Length=207, Percent_Identity=29.951690821256, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI145693105, Length=283, Percent_Identity=24.0282685512367, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082132, Length=138, Percent_Identity=28.9855072463768, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788481, Length=296, Percent_Identity=25.3378378378378, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI2367136, Length=228, Percent_Identity=22.3684210526316, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788887, Length=240, Percent_Identity=28.3333333333333, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790399, Length=238, Percent_Identity=21.0084033613445, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34600; Mature: 34469

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIDVVVNQRHLQIQLKQLETVWHTVINGYNLSQAATVLHTSQSSLSKHIAALENQLKTE
CEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VFVRQGKRLTGLTTMGTALMPHIESIFTEIRTIENLSLDFNNPNVGTLTIATTHTQARYV
HHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCEEEEEEEECCCHHHH
LPEVVKEFKERFPKVNLILQQADPETIAQMVIRGQADIGIATESLLHNNYLRCYRYYDWT
HHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEECCE
HRVIVPSDHELAGLESIDLPTLASYPIVTYHGGFTGRGAIDKTFSDAGLEPDIVLAALDA
EEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHCCCCCCCEEEEEHHH
DVISTYVGLGLGIGIIAEMAFEPSHYQNLTAIPVDHFGRFTSWMAVRDDAEIRQYGRAFM
HHHHHHHHHHHHHHHHHHHHCCCCHHCCEEECCHHHHHHHHHHHEECCCHHHHHHHHHHH
ELCQKQFSQ
HHHHHHHCC
>Mature Secondary Structure 
AIDVVVNQRHLQIQLKQLETVWHTVINGYNLSQAATVLHTSQSSLSKHIAALENQLKTE
EEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VFVRQGKRLTGLTTMGTALMPHIESIFTEIRTIENLSLDFNNPNVGTLTIATTHTQARYV
HHHHCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCEEEEEEEECCCHHHH
LPEVVKEFKERFPKVNLILQQADPETIAQMVIRGQADIGIATESLLHNNYLRCYRYYDWT
HHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEEEECCE
HRVIVPSDHELAGLESIDLPTLASYPIVTYHGGFTGRGAIDKTFSDAGLEPDIVLAALDA
EEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHCCCCCCCEEEEEHHH
DVISTYVGLGLGIGIIAEMAFEPSHYQNLTAIPVDHFGRFTSWMAVRDDAEIRQYGRAFM
HHHHHHHHHHHHHHHHHHHHCCCCHHCCEEECCHHHHHHHHHHHEECCCHHHHHHHHHHH
ELCQKQFSQ
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8529872; 9097040; 9278503 [H]