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The map label for this gene is nhaC [H]

Identifier: 93005724

GI number: 93005724

Start: 1061168

End: 1062637

Strand: Direct

Name: nhaC [H]

Synonym: Pcryo_0896

Alternate gene names: 93005724

Gene position: 1061168-1062637 (Clockwise)

Preceding gene: 93005723

Following gene: 93005725

Centisome position: 34.68

GC content: 45.51

Gene sequence:

>1470_bases
ATGATTGCAGATAAACCTCACAAACCGCATGACCCTGATATCGAAGGTTATGATCCTTCTTCTAGCTTCCTGCTAGATAT
TGCCCCACTGATACTGACTGCCATTATTCTAATGGTGCAATTTTTTGTCTTTAAAGATTTTACTCCGCATATTCCGCTAG
CATGTGGCATCTTGATCACCGGTCTGTTTATGAAGATACGTGGTCGCAGCTGGGATGGTATGGAAGAGCGTTTTTTAAAG
GTTGTGAAAATTGGTCTGCCTGCCATGATCATCTTGATGGGTGTAGGGATGCTCATCGGTGCTTGGATTATCGCCGGCAC
TGTACCCACTATTTTATACTACGGCTTTAGTGTTTTTTCTCCCTCCTCATTTCTAGTCTCTGTTTGTCTTATTTGTGCCA
TTATTTCAGTAGCAACGGGTACCTCTTGGGGCACGGTTGGCACAGTCGGTTTAGCTATGATGGGTATTGGTTTGGGGTTA
GGTATTCCACCGTCACTAACAGGTGGTGCCATCGTCTCTGGTGCTTTTTTTGGCGACAAAATGTCTCCGTTGTCTGACAC
CACGAACTTAACACCAGCTGCTGCCGGTGTTGACCTCTGGGACCATATCCGTGGCATGTTGCCGACGACTGTACCTGCCA
TGGTGACTGCTCTGATTCTCTATGCTTGGATTGGTATGAGCTACGGCGCAGACAATGTCGATCTCACCTCAATCAAAGAA
ATACAAACCTCATTAGCAGCGAACTATAACCTGAGCATTATTACTTTATTACCTGCTGTTGTCGTCGTCATTGCAGCTGT
TATGAAAATGCCAGCCATTCCAACGGTATTGTCAGGTGTGGTAGTCGCAGGTCTTGTCGCATTCTTTATGCAAGGCGTCG
GTGTCCATGACATCTTTAACGTCCTACAAAACGGTTTTAAAAGTGAGACCGGCTTTGCTGTGGTCGATCAACTGTTGTCT
AAAGGTGGCGTGATGTCCATGACTTGGGTCGTGACCTTAACTATCTTTGCACTAGCTTTTGTCGGTTCAATTGAGCATTA
CGGTACATTAAAAGCCATCATGGCCAAAATCAACAACATGGTGAAATCGAGATTTGGTTTAGTGATTACGACTTATGCCA
GTACCATCGGTGTTGGTACGCTTATCGGTGATGTCTATACCACGCTAGTCTTACCGGGTCGTCTGCTCAAAGATAAGTAT
AAAGAGATGGGTTACAAGCGCACGACGCTTACTCGCTCTATCGAAGATACGGGTACGCTGTTATCGCCACTTATTCCTTG
GAATATGGGCGGTAGCTTTGTCGCGGCAACCCTAGGTATTGCGACCTTAACTTACGCTCCATTCGCCTTTGCCTGCTGGT
TATCACCATTGTTTGGCTTGCTATGGGTCGTCTTAAATAAATTTATTCCTCGTGAAAAACCGACTGTCATCGATAACACA
AGCACGCTCTCTACCGTAGAAAACGTATAA

Upstream 100 bases:

>100_bases
TAGGTCACTAGATTGGTTTGCATCTGACCAATGAGCAACATCGTACGATGACTATATACCAATGGATTTGGTTTTAACTA
CTAGGATAGGTAGATATATT

Downstream 100 bases:

>100_bases
TTTAGAAGGAACTTGAGATGTTGCAAGAGCAATGTTTGTGGAGCGTCACTGCGCCCAAAACTCACCACTACGATACCCTA
ACAAGCGAAACGCAAACACG

Product: Na+/H+ antiporter NhaC

Products: NA

Alternate protein names: Sodium/hydrogen antiporter; Sodium/proton antiporter [H]

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MIADKPHKPHDPDIEGYDPSSSFLLDIAPLILTAIILMVQFFVFKDFTPHIPLACGILITGLFMKIRGRSWDGMEERFLK
VVKIGLPAMIILMGVGMLIGAWIIAGTVPTILYYGFSVFSPSSFLVSVCLICAIISVATGTSWGTVGTVGLAMMGIGLGL
GIPPSLTGGAIVSGAFFGDKMSPLSDTTNLTPAAAGVDLWDHIRGMLPTTVPAMVTALILYAWIGMSYGADNVDLTSIKE
IQTSLAANYNLSIITLLPAVVVVIAAVMKMPAIPTVLSGVVVAGLVAFFMQGVGVHDIFNVLQNGFKSETGFAVVDQLLS
KGGVMSMTWVVTLTIFALAFVGSIEHYGTLKAIMAKINNMVKSRFGLVITTYASTIGVGTLIGDVYTTLVLPGRLLKDKY
KEMGYKRTTLTRSIEDTGTLLSPLIPWNMGGSFVAATLGIATLTYAPFAFACWLSPLFGLLWVVLNKFIPREKPTVIDNT
STLSTVENV

Sequences:

>Translated_489_residues
MIADKPHKPHDPDIEGYDPSSSFLLDIAPLILTAIILMVQFFVFKDFTPHIPLACGILITGLFMKIRGRSWDGMEERFLK
VVKIGLPAMIILMGVGMLIGAWIIAGTVPTILYYGFSVFSPSSFLVSVCLICAIISVATGTSWGTVGTVGLAMMGIGLGL
GIPPSLTGGAIVSGAFFGDKMSPLSDTTNLTPAAAGVDLWDHIRGMLPTTVPAMVTALILYAWIGMSYGADNVDLTSIKE
IQTSLAANYNLSIITLLPAVVVVIAAVMKMPAIPTVLSGVVVAGLVAFFMQGVGVHDIFNVLQNGFKSETGFAVVDQLLS
KGGVMSMTWVVTLTIFALAFVGSIEHYGTLKAIMAKINNMVKSRFGLVITTYASTIGVGTLIGDVYTTLVLPGRLLKDKY
KEMGYKRTTLTRSIEDTGTLLSPLIPWNMGGSFVAATLGIATLTYAPFAFACWLSPLFGLLWVVLNKFIPREKPTVIDNT
STLSTVENV
>Mature_489_residues
MIADKPHKPHDPDIEGYDPSSSFLLDIAPLILTAIILMVQFFVFKDFTPHIPLACGILITGLFMKIRGRSWDGMEERFLK
VVKIGLPAMIILMGVGMLIGAWIIAGTVPTILYYGFSVFSPSSFLVSVCLICAIISVATGTSWGTVGTVGLAMMGIGLGL
GIPPSLTGGAIVSGAFFGDKMSPLSDTTNLTPAAAGVDLWDHIRGMLPTTVPAMVTALILYAWIGMSYGADNVDLTSIKE
IQTSLAANYNLSIITLLPAVVVVIAAVMKMPAIPTVLSGVVVAGLVAFFMQGVGVHDIFNVLQNGFKSETGFAVVDQLLS
KGGVMSMTWVVTLTIFALAFVGSIEHYGTLKAIMAKINNMVKSRFGLVITTYASTIGVGTLIGDVYTTLVLPGRLLKDKY
KEMGYKRTTLTRSIEDTGTLLSPLIPWNMGGSFVAATLGIATLTYAPFAFACWLSPLFGLLWVVLNKFIPREKPTVIDNT
STLSTVENV

Specific function: Na(+)/H(+) antiporter. Involved in pH homeostasis and sodium extrusion [H]

COG id: COG1757

COG function: function code C; Na+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nhaC Na(+)/H(+) antiporter family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004770
- InterPro:   IPR018461 [H]

Pfam domain/function: PF03553 Na_H_antiporter [H]

EC number: NA

Molecular weight: Translated: 52169; Mature: 52169

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCC
>Mature Secondary Structure
MIADKPHKPHDPDIEGYDPSSSFLLDIAPLILTAIILMVQFFVFKDFTPHIPLACGILIT
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
GLFMKIRGRSWDGMEERFLKVVKIGLPAMIILMGVGMLIGAWIIAGTVPTILYYGFSVFS
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PSSFLVSVCLICAIISVATGTSWGTVGTVGLAMMGIGLGLGIPPSLTGGAIVSGAFFGDK
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCHHCCCC
MSPLSDTTNLTPAAAGVDLWDHIRGMLPTTVPAMVTALILYAWIGMSYGADNVDLTSIKE
CCCCCCCCCCCCHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
IQTSLAANYNLSIITLLPAVVVVIAAVMKMPAIPTVLSGVVVAGLVAFFMQGVGVHDIFN
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VLQNGFKSETGFAVVDQLLSKGGVMSMTWVVTLTIFALAFVGSIEHYGTLKAIMAKINNM
HHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKSRFGLVITTYASTIGVGTLIGDVYTTLVLPGRLLKDKYKEMGYKRTTLTRSIEDTGTL
HHHHHCCCEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LSPLIPWNMGGSFVAATLGIATLTYAPFAFACWLSPLFGLLWVVLNKFIPREKPTVIDNT
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCC
STLSTVENV
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1660475; 9190799 [H]