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The map label for this gene is pcaR [H]

Identifier: 93005644

GI number: 93005644

Start: 961417

End: 962244

Strand: Reverse

Name: pcaR [H]

Synonym: Pcryo_0814

Alternate gene names: 93005644

Gene position: 962244-961417 (Counterclockwise)

Preceding gene: 93005647

Following gene: 93005643

Centisome position: 31.45

GC content: 47.46

Gene sequence:

>828_bases
ATGAGAAAAAATATGCTGGTATCTGCACCATTATTGGATCGATTAAATAGCTCCCTTACCCAAGGTAAAGAAGACAACGA
TAGGCAATTTGTCACTGCCCTTGGACGTGGCTTAATGATATTGGCAGCTTTTGAGCATGAAGAGGCGCTTAGCCATCAGC
AATTATGCCAGATGACAAAATTGCCAAAAGCGACGATTACTCGTCTGATTCATACCTTGATGACGCTTGGATTTTTGCGC
GTGACGCTACATGGACAGTATCAATTGGGTAGTAGTGCGGTGCGATTAAGTGCAACAGCGTGGAGTCGTCATGATTTAGT
GGCAGCAGCTGAACCGTTATTGCGGCAGTTTGCCAGTCAAAACGAGGTGTCGGTGAATTTAGCAACCGAAGTCGAAGGGG
AGATGCGCTATCACGCTTGTTGTCGTAGCCCTGCCCGCCTATCGGTCAATTTGCAAGTTGGCTCAGCCGTTCCCGTCGCC
CGAACCGCTATTGGACGTGCTTTTTATGCGGCTAGTTCGCAAATACGACAGGCTGTTATTCGTAGTAATTTACAAGAGCA
GCTATCAGCAGAAGATTATAACCATGCGCAGGCTGCTTTATCTGACGCCGCAGAACATTATAGAATGCATGGTTATACCG
TATCGGATGGTGAGTTCTCTACGGACATATTAGCAGTGGCCGTTGGTGTCTTTGATGTTGCGACTGGGCAATATGCGTAT
TCACTCAATGCCAGTGTCCCAAGTGCCAATTGGGAAAGCGAAGACTATGCGGCGATGATAGTACCTAAGTTGCAAGCGTT
GGCTGAAAGGATTGGCAGCGGGGTTTAA

Upstream 100 bases:

>100_bases
ACTTCAAAATTCCGCTATGCGAAACTTAGTTTCATAATATAAACTATTTAAGCAAAATTTTAGCGTCCTGTAAACCCTTA
TTCATTCAGATGGTTATAAA

Downstream 100 bases:

>100_bases
ACTAATTGAGTTGCTAGGTAAGTTTTAACTTAGTTTACCAATGATACTAAAGCCTTTCGATGCAATCACAAAGTGATTTG
GTCTAAGTGCTATACACTTT

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MRKNMLVSAPLLDRLNSSLTQGKEDNDRQFVTALGRGLMILAAFEHEEALSHQQLCQMTKLPKATITRLIHTLMTLGFLR
VTLHGQYQLGSSAVRLSATAWSRHDLVAAAEPLLRQFASQNEVSVNLATEVEGEMRYHACCRSPARLSVNLQVGSAVPVA
RTAIGRAFYAASSQIRQAVIRSNLQEQLSAEDYNHAQAALSDAAEHYRMHGYTVSDGEFSTDILAVAVGVFDVATGQYAY
SLNASVPSANWESEDYAAMIVPKLQALAERIGSGV

Sequences:

>Translated_275_residues
MRKNMLVSAPLLDRLNSSLTQGKEDNDRQFVTALGRGLMILAAFEHEEALSHQQLCQMTKLPKATITRLIHTLMTLGFLR
VTLHGQYQLGSSAVRLSATAWSRHDLVAAAEPLLRQFASQNEVSVNLATEVEGEMRYHACCRSPARLSVNLQVGSAVPVA
RTAIGRAFYAASSQIRQAVIRSNLQEQLSAEDYNHAQAALSDAAEHYRMHGYTVSDGEFSTDILAVAVGVFDVATGQYAY
SLNASVPSANWESEDYAAMIVPKLQALAERIGSGV
>Mature_275_residues
MRKNMLVSAPLLDRLNSSLTQGKEDNDRQFVTALGRGLMILAAFEHEEALSHQQLCQMTKLPKATITRLIHTLMTLGFLR
VTLHGQYQLGSSAVRLSATAWSRHDLVAAAEPLLRQFASQNEVSVNLATEVEGEMRYHACCRSPARLSVNLQVGSAVPVA
RTAIGRAFYAASSQIRQAVIRSNLQEQLSAEDYNHAQAALSDAAEHYRMHGYTVSDGEFSTDILAVAVGVFDVATGQYAY
SLNASVPSANWESEDYAAMIVPKLQALAERIGSGV

Specific function: Positive regulator of all genes within the pca regulon, pcaBDC, pcaIJ and pcaF. Also required for the chemotactic response to aromatic compounds [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=244, Percent_Identity=25.4098360655738, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29979; Mature: 29979

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKNMLVSAPLLDRLNSSLTQGKEDNDRQFVTALGRGLMILAAFEHEEALSHQQLCQMTK
CCCCEEEECHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHC
LPKATITRLIHTLMTLGFLRVTLHGQYQLGSSAVRLSATAWSRHDLVAAAEPLLRQFASQ
CCHHHHHHHHHHHHHHHHHHHEEECCEEECCCCEEEEEHHCCHHHHHHHHHHHHHHHCCC
NEVSVNLATEVEGEMRYHACCRSPARLSVNLQVGSAVPVARTAIGRAFYAASSQIRQAVI
CCEEEEEEECCCCHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
RSNLQEQLSAEDYNHAQAALSDAAEHYRMHGYTVSDGEFSTDILAVAVGVFDVATGQYAY
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHCCCCEEE
SLNASVPSANWESEDYAAMIVPKLQALAERIGSGV
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRKNMLVSAPLLDRLNSSLTQGKEDNDRQFVTALGRGLMILAAFEHEEALSHQQLCQMTK
CCCCEEEECHHHHHHHHHHHCCCCCCHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHC
LPKATITRLIHTLMTLGFLRVTLHGQYQLGSSAVRLSATAWSRHDLVAAAEPLLRQFASQ
CCHHHHHHHHHHHHHHHHHHHEEECCEEECCCCEEEEEHHCCHHHHHHHHHHHHHHHCCC
NEVSVNLATEVEGEMRYHACCRSPARLSVNLQVGSAVPVARTAIGRAFYAASSQIRQAVI
CCEEEEEEECCCCHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
RSNLQEQLSAEDYNHAQAALSDAAEHYRMHGYTVSDGEFSTDILAVAVGVFDVATGQYAY
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHCCCCEEE
SLNASVPSANWESEDYAAMIVPKLQALAERIGSGV
EECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083169 [H]