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The map label for this gene is nadA [H]

Identifier: 93005430

GI number: 93005430

Start: 715289

End: 716428

Strand: Reverse

Name: nadA [H]

Synonym: Pcryo_0600

Alternate gene names: 93005430

Gene position: 716428-715289 (Counterclockwise)

Preceding gene: 93005434

Following gene: 93005429

Centisome position: 23.41

GC content: 46.58

Gene sequence:

>1140_bases
ATGAAAACGTATCCGTATGACGCACCGATTATGAGTACTGATAATCGCATTGCCACGCAAATGAATATTGAATATGCCAA
AGCAAAAATGCCCGCAGATTTGCCGCGTAGTGAGCGACTGAAAGTTGAAGAAAATATTAAGCAGTTGTTAAAAGAGCATA
ATGCCGTCTTAGTCGCGCATTATTATGTCGATCCCTTTATTCAGGATTTGGCATTAGCAACCGGCGGCTGTGTTGGTGAT
TCGCTTGAGATGGCGCGCTTTGGTCAAGCGCATAGTGCACAAACACTGGTAGTTGCAGGTGTACGCTTTATGGGTGAGTC
GGCAAAGATACTCAGTATGGAAAAAACAGTACTGATGCCAGACTTGGAAGCAGAATGCTCGCTTGATTTGGGCTGCCCTG
CCGATGAATTTTCTGCCTTTTGTGATGCGTATCCTGAGCGTACCGTAGTGGTCTACGCCAATACCAGTGCGGCAGTAAAA
GCACGGGCTGATTGGGTAGTAACTTCGTCAGTTGGTATCAATATCATTCGACATTTGCAAGAACAAGGCGAGCCTATCAT
TTGGGGTCCGGATAGACACTTAGGTAAATACATTGCCCATGAGACTGGGGCAGATATGCTGCTATGGCAAGGTTCATGTA
TGGTGCATAATGAGTTTAAAGCCACTGAGCTTGAACAATTAAAAGCTGAACATCCGACAGCAAAAGTCTTGGTACATCCT
GAATCTCCAGATAGTGTCGTGGCGCTTGCCGATGTGGTTGGCTCGACCAGTAAGCTATTGCAATCCACCTATGAGATGGA
TGCCGATACCTTTATCGTCGCAACTGACTTGGGTATCTTGCATGAGATGCAAAAGCGCTCGCCAAACAAGCGCTTCTTGG
CTGCACCGACTGCGGGCGAAAGTGCAAGCTGCAAAAGCTGTGCTTTTTGTCCATGGATGGCGATGAATGGTCTACAAGGT
ATCGAGCAATGTTTGACCAATAATTCAGGTGAGATATTGATGACGGCTGAGCTGGCAGCGGCAGCTAGAAAGCCATTACA
ACGCATGCTTGATTTTGCTGAATCACAAAAACAGCGGGTAGCAGCAAGCGGTGATATCGTCAAAGACCGTGCATTGTTTG
CAAATGTTGGAGCAGCATAA

Upstream 100 bases:

>100_bases
CAAAATGAGCATAATTAAAACAGTTTATTTTTTAGCACTATTCAACTGACTCAATCTAACGGCAACTGACGTGTCGTTAT
TGCATGAAAGGTTTGCACTT

Downstream 100 bases:

>100_bases
TATGAGCGCGAACTGGTTAAATGGCAAAGATAACTGTAATGCACATCAGATCCTTGATGCTGTTGTGATAACAGATGTAC
TTATCGTTGGGGCTGGGCTT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKTYPYDAPIMSTDNRIATQMNIEYAKAKMPADLPRSERLKVEENIKQLLKEHNAVLVAHYYVDPFIQDLALATGGCVGD
SLEMARFGQAHSAQTLVVAGVRFMGESAKILSMEKTVLMPDLEAECSLDLGCPADEFSAFCDAYPERTVVVYANTSAAVK
ARADWVVTSSVGINIIRHLQEQGEPIIWGPDRHLGKYIAHETGADMLLWQGSCMVHNEFKATELEQLKAEHPTAKVLVHP
ESPDSVVALADVVGSTSKLLQSTYEMDADTFIVATDLGILHEMQKRSPNKRFLAAPTAGESASCKSCAFCPWMAMNGLQG
IEQCLTNNSGEILMTAELAAAARKPLQRMLDFAESQKQRVAASGDIVKDRALFANVGAA

Sequences:

>Translated_379_residues
MKTYPYDAPIMSTDNRIATQMNIEYAKAKMPADLPRSERLKVEENIKQLLKEHNAVLVAHYYVDPFIQDLALATGGCVGD
SLEMARFGQAHSAQTLVVAGVRFMGESAKILSMEKTVLMPDLEAECSLDLGCPADEFSAFCDAYPERTVVVYANTSAAVK
ARADWVVTSSVGINIIRHLQEQGEPIIWGPDRHLGKYIAHETGADMLLWQGSCMVHNEFKATELEQLKAEHPTAKVLVHP
ESPDSVVALADVVGSTSKLLQSTYEMDADTFIVATDLGILHEMQKRSPNKRFLAAPTAGESASCKSCAFCPWMAMNGLQG
IEQCLTNNSGEILMTAELAAAARKPLQRMLDFAESQKQRVAASGDIVKDRALFANVGAA
>Mature_379_residues
MKTYPYDAPIMSTDNRIATQMNIEYAKAKMPADLPRSERLKVEENIKQLLKEHNAVLVAHYYVDPFIQDLALATGGCVGD
SLEMARFGQAHSAQTLVVAGVRFMGESAKILSMEKTVLMPDLEAECSLDLGCPADEFSAFCDAYPERTVVVYANTSAAVK
ARADWVVTSSVGINIIRHLQEQGEPIIWGPDRHLGKYIAHETGADMLLWQGSCMVHNEFKATELEQLKAEHPTAKVLVHP
ESPDSVVALADVVGSTSKLLQSTYEMDADTFIVATDLGILHEMQKRSPNKRFLAAPTAGESASCKSCAFCPWMAMNGLQG
IEQCLTNNSGEILMTAELAAAARKPLQRMLDFAESQKQRVAASGDIVKDRALFANVGAA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=335, Percent_Identity=59.4029850746269, Blast_Score=418, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 41340; Mature: 41340

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYPYDAPIMSTDNRIATQMNIEYAKAKMPADLPRSERLKVEENIKQLLKEHNAVLVAH
CCCCCCCCCEECCCCCEEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEE
YYVDPFIQDLALATGGCVGDSLEMARFGQAHSAQTLVVAGVRFMGESAKILSMEKTVLMP
EHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCEEEEEHHHHCCCCCEEEEECCEEECC
DLEAECSLDLGCPADEFSAFCDAYPERTVVVYANTSAAVKARADWVVTSSVGINIIRHLQ
CCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEECHHHHHHHHHHH
EQGEPIIWGPDRHLGKYIAHETGADMLLWQGSCMVHNEFKATELEQLKAEHPTAKVLVHP
HCCCCEEECCCHHHHHHHHHCCCCCEEEECCCEEEECCCCHHHHHHHHHCCCCEEEEECC
ESPDSVVALADVVGSTSKLLQSTYEMDADTFIVATDLGILHEMQKRSPNKRFLAAPTAGE
CCCCHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCCCEEEECCCCCC
SASCKSCAFCPWMAMNGLQGIEQCLTNNSGEILMTAELAAAARKPLQRMLDFAESQKQRV
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
AASGDIVKDRALFANVGAA
HHCCCCHHHHHHHHCCCCC
>Mature Secondary Structure
MKTYPYDAPIMSTDNRIATQMNIEYAKAKMPADLPRSERLKVEENIKQLLKEHNAVLVAH
CCCCCCCCCEECCCCCEEEEEEHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEE
YYVDPFIQDLALATGGCVGDSLEMARFGQAHSAQTLVVAGVRFMGESAKILSMEKTVLMP
EHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCEEEEEHHHHCCCCCEEEEECCEEECC
DLEAECSLDLGCPADEFSAFCDAYPERTVVVYANTSAAVKARADWVVTSSVGINIIRHLQ
CCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEECHHHHHHHHHHH
EQGEPIIWGPDRHLGKYIAHETGADMLLWQGSCMVHNEFKATELEQLKAEHPTAKVLVHP
HCCCCEEECCCHHHHHHHHHCCCCCEEEECCCEEEECCCCHHHHHHHHHCCCCEEEEECC
ESPDSVVALADVVGSTSKLLQSTYEMDADTFIVATDLGILHEMQKRSPNKRFLAAPTAGE
CCCCHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHCCCCCEEEECCCCCC
SASCKSCAFCPWMAMNGLQGIEQCLTNNSGEILMTAELAAAARKPLQRMLDFAESQKQRV
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
AASGDIVKDRALFANVGAA
HHCCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA