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The map label for this gene is yngE [H]

Identifier: 93005171

GI number: 93005171

Start: 411864

End: 413474

Strand: Direct

Name: yngE [H]

Synonym: Pcryo_0340

Alternate gene names: 93005171

Gene position: 411864-413474 (Clockwise)

Preceding gene: 93005170

Following gene: 93005172

Centisome position: 13.46

GC content: 47.55

Gene sequence:

>1611_bases
ATGAGCGCTATCATAACCAGTAAACTGAGTCCAAATGCCGCTGAATTTCAGCAGAACAGTGCTGCAATGCAAGAGGTCGT
CGATGACTTGTATCAGCATCTGCGTAAAGTCGCCCAAGGTGGTTCAGAGCGTGCACGCGCCAAGCATTTAGCACGTGGTA
AGCTACTACCTCGTGAGCGTGTCGAGCGTTTGCTTGATGTTGGTACGCCATTTTTAGAAGTAGCTCCGATGGCAGCGCAC
GATATGTATGGCGAAGATATTCCAGCGGCGGGCGTGATTGCTGGTATCGGTCGTATCAATGGCATCGAGTGTATGATTGT
CTGTAATGATGCCACGGTAAAGGGTGGTACTTATTATCCAATGACGGTCAAAAAACATCTACGTGCCCAAGAAATTGCCC
AAGAAAACAACTTGCCTTGTGTCTACTTAGTCGATTCTGGCGGTGCAAACTTGCCCAATCAGGATGAAGTATTCCCTGAT
AAAGAGCACTTCGGACGTATATTTTTTAATCAGGCGAATATGAGTGCCGCTGGCATTCCACAGATTGCGGTGGTCATGGG
CAGCTGTACGGCTGGTGGAGCTTATGTACCAGCGATGAGTGACGAGTCTATTATTGTTAAAGAACAAGGAACTATTTTTT
TAGGTGGTCCGCCACTGGTCAAAGCGGCAACAGGTGAAGAGGTCACAGCAGAAGATTTGGGCGGCGGTGATGTACATACC
CGTCTGTCGGGGGTGGTCGATCATTTGGCGCAAAACGATACCCATGCGTTATCAATCGCGCGTAATATCGTTAGCCACTT
AAACCGTTCTGCTAAACAGATCCCAAATCAAATAAAACCACGTCCACCGCGCTATGATGCTAAAGAGCTATATGGCGTCA
TTCCAACCGATAAACGTAAGCCATTTGATATTAGAGAAATCATTGCTCGTATCGTCGATGACAGTGCCTTTGATGAATTT
AAGGCGCGCTTTGGTACGACGCTGGTTTGTGGTTTTGCTCATATTGAAGGTATGCCAGTTGGCATTATTGCCAATAATGG
CATCTTATTTAGTGAATCGGCGCAAAAAGGTACGCACTTTATTGAGCTGTGCTGTAAACGCAAAATTCCTTTAATATTCC
TACAAAACATCACCGGCTTTATGGTCGGGCGAAAATACGAAAACGAAGGTATTGCCCGTCATGGTGCCAAGATGGTGATG
GCGGTAGCGAATGCCAAAGTACCAAAATTCACCGTTATCGTTGGTGGCTCATTCGGTGCGGGTAACTACGGTATGTGTGG
ACGTGCTTATAGCCCGCGCTTCTTATGGATGTGGCCAAATGCGCGCATTTCTGTGATGGGCGGCGAGCAAGCAGCGTCGG
TACTAGCAACGGTTAAGCGCGATAACTTTGACCGCAAAGGCGAAGCGTGGAGCGATGAAGACGAAGCAGCATTTAAAGCG
CCGATTCGTGAGATGTACGAAGAGCAAGGTCATCCTTATTATGCTACCGCTCGTTTATGGGATGATGGCGTGATTGACCC
TGCTGATACCCGTAATGTGTTGGCATTAGCGCTTAGCGCGGCTCATAACGCACCGATTGAAGAGACAAAATTTGGTGTCT
TTAGAATGTAG

Upstream 100 bases:

>100_bases
TTTACTAATAAATTTTTCAGTAAATATTAAAATAACCAGTAGTTAAAAAAATTCGCATAAAAAAGCTACTCGCATTTACG
CATTAAAGAAAAGGGATATC

Downstream 100 bases:

>100_bases
CAATGAACGGTATATTGACAGTCATTTAGTGCTCATCAATACATAAAATATAGAGAAAGATATGCAACAAAATTTGAATC
ATTATAAAAGTCTATTGGTT

Product: propionyl-CoA carboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 536; Mature: 535

Protein sequence:

>536_residues
MSAIITSKLSPNAAEFQQNSAAMQEVVDDLYQHLRKVAQGGSERARAKHLARGKLLPRERVERLLDVGTPFLEVAPMAAH
DMYGEDIPAAGVIAGIGRINGIECMIVCNDATVKGGTYYPMTVKKHLRAQEIAQENNLPCVYLVDSGGANLPNQDEVFPD
KEHFGRIFFNQANMSAAGIPQIAVVMGSCTAGGAYVPAMSDESIIVKEQGTIFLGGPPLVKAATGEEVTAEDLGGGDVHT
RLSGVVDHLAQNDTHALSIARNIVSHLNRSAKQIPNQIKPRPPRYDAKELYGVIPTDKRKPFDIREIIARIVDDSAFDEF
KARFGTTLVCGFAHIEGMPVGIIANNGILFSESAQKGTHFIELCCKRKIPLIFLQNITGFMVGRKYENEGIARHGAKMVM
AVANAKVPKFTVIVGGSFGAGNYGMCGRAYSPRFLWMWPNARISVMGGEQAASVLATVKRDNFDRKGEAWSDEDEAAFKA
PIREMYEEQGHPYYATARLWDDGVIDPADTRNVLALALSAAHNAPIEETKFGVFRM

Sequences:

>Translated_536_residues
MSAIITSKLSPNAAEFQQNSAAMQEVVDDLYQHLRKVAQGGSERARAKHLARGKLLPRERVERLLDVGTPFLEVAPMAAH
DMYGEDIPAAGVIAGIGRINGIECMIVCNDATVKGGTYYPMTVKKHLRAQEIAQENNLPCVYLVDSGGANLPNQDEVFPD
KEHFGRIFFNQANMSAAGIPQIAVVMGSCTAGGAYVPAMSDESIIVKEQGTIFLGGPPLVKAATGEEVTAEDLGGGDVHT
RLSGVVDHLAQNDTHALSIARNIVSHLNRSAKQIPNQIKPRPPRYDAKELYGVIPTDKRKPFDIREIIARIVDDSAFDEF
KARFGTTLVCGFAHIEGMPVGIIANNGILFSESAQKGTHFIELCCKRKIPLIFLQNITGFMVGRKYENEGIARHGAKMVM
AVANAKVPKFTVIVGGSFGAGNYGMCGRAYSPRFLWMWPNARISVMGGEQAASVLATVKRDNFDRKGEAWSDEDEAAFKA
PIREMYEEQGHPYYATARLWDDGVIDPADTRNVLALALSAAHNAPIEETKFGVFRM
>Mature_535_residues
SAIITSKLSPNAAEFQQNSAAMQEVVDDLYQHLRKVAQGGSERARAKHLARGKLLPRERVERLLDVGTPFLEVAPMAAHD
MYGEDIPAAGVIAGIGRINGIECMIVCNDATVKGGTYYPMTVKKHLRAQEIAQENNLPCVYLVDSGGANLPNQDEVFPDK
EHFGRIFFNQANMSAAGIPQIAVVMGSCTAGGAYVPAMSDESIIVKEQGTIFLGGPPLVKAATGEEVTAEDLGGGDVHTR
LSGVVDHLAQNDTHALSIARNIVSHLNRSAKQIPNQIKPRPPRYDAKELYGVIPTDKRKPFDIREIIARIVDDSAFDEFK
ARFGTTLVCGFAHIEGMPVGIIANNGILFSESAQKGTHFIELCCKRKIPLIFLQNITGFMVGRKYENEGIARHGAKMVMA
VANAKVPKFTVIVGGSFGAGNYGMCGRAYSPRFLWMWPNARISVMGGEQAASVLATVKRDNFDRKGEAWSDEDEAAFKAP
IREMYEEQGHPYYATARLWDDGVIDPADTRNVLALALSAAHNAPIEETKFGVFRM

Specific function: Unknown

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI11545863, Length=526, Percent_Identity=64.4486692015209, Blast_Score=709, Evalue=0.0,
Organism=Homo sapiens, GI119943100, Length=502, Percent_Identity=32.8685258964143, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI295821216, Length=522, Percent_Identity=32.183908045977, Blast_Score=223, Evalue=3e-58,
Organism=Homo sapiens, GI310133460, Length=135, Percent_Identity=54.0740740740741, Blast_Score=151, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17552936, Length=535, Percent_Identity=60.5607476635514, Blast_Score=702, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25147362, Length=484, Percent_Identity=34.0909090909091, Blast_Score=242, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI25147359, Length=484, Percent_Identity=34.0909090909091, Blast_Score=241, Evalue=5e-64,
Organism=Drosophila melanogaster, GI24586065, Length=550, Percent_Identity=63.6363636363636, Blast_Score=737, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: NA

Molecular weight: Translated: 58406; Mature: 58274

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIITSKLSPNAAEFQQNSAAMQEVVDDLYQHLRKVAQGGSERARAKHLARGKLLPRER
CCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHH
VERLLDVGTPFLEVAPMAAHDMYGEDIPAAGVIAGIGRINGIECMIVCNDATVKGGTYYP
HHHHHHCCCCHHHHCCHHHHHCCCCCCCCHHHHHHHCCCCCEEEEEEECCCEECCCEECC
MTVKKHLRAQEIAQENNLPCVYLVDSGGANLPNQDEVFPDKEHFGRIFFNQANMSAAGIP
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHCCEEEEEECCCCCCCCC
QIAVVMGSCTAGGAYVPAMSDESIIVKEQGTIFLGGPPLVKAATGEEVTAEDLGGGDVHT
EEEEEEECCCCCCEEECCCCCCEEEEEECCEEEECCCCEEEECCCCCCCHHHCCCCHHHH
RLSGVVDHLAQNDTHALSIARNIVSHLNRSAKQIPNQIKPRPPRYDAKELYGVIPTDKRK
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHEECCCCCCCC
PFDIREIIARIVDDSAFDEFKARFGTTLVCGFAHIEGMPVGIIANNGILFSESAQKGTHF
CCCHHHHHHHHHCCHHHHHHHHHHCCEEEEEHHHHCCCEEEEEECCCEEEECCCCCCHHH
IELCCKRKIPLIFLQNITGFMVGRKYENEGIARHGAKMVMAVANAKVPKFTVIVGGSFGA
HHHHHHCCCCEEEECCCHHHHHCCEECCCCHHHHHHHEEEEECCCCCCEEEEEEECCCCC
GNYGMCGRAYSPRFLWMWPNARISVMGGEQAASVLATVKRDNFDRKGEAWSDEDEAAFKA
CCCCCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
PIREMYEEQGHPYYATARLWDDGVIDPADTRNVLALALSAAHNAPIEETKFGVFRM
HHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SAIITSKLSPNAAEFQQNSAAMQEVVDDLYQHLRKVAQGGSERARAKHLARGKLLPRER
CCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHH
VERLLDVGTPFLEVAPMAAHDMYGEDIPAAGVIAGIGRINGIECMIVCNDATVKGGTYYP
HHHHHHCCCCHHHHCCHHHHHCCCCCCCCHHHHHHHCCCCCEEEEEEECCCEECCCEECC
MTVKKHLRAQEIAQENNLPCVYLVDSGGANLPNQDEVFPDKEHFGRIFFNQANMSAAGIP
HHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCHHHCCEEEEEECCCCCCCCC
QIAVVMGSCTAGGAYVPAMSDESIIVKEQGTIFLGGPPLVKAATGEEVTAEDLGGGDVHT
EEEEEEECCCCCCEEECCCCCCEEEEEECCEEEECCCCEEEECCCCCCCHHHCCCCHHHH
RLSGVVDHLAQNDTHALSIARNIVSHLNRSAKQIPNQIKPRPPRYDAKELYGVIPTDKRK
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCHHHHEECCCCCCCC
PFDIREIIARIVDDSAFDEFKARFGTTLVCGFAHIEGMPVGIIANNGILFSESAQKGTHF
CCCHHHHHHHHHCCHHHHHHHHHHCCEEEEEHHHHCCCEEEEEECCCEEEECCCCCCHHH
IELCCKRKIPLIFLQNITGFMVGRKYENEGIARHGAKMVMAVANAKVPKFTVIVGGSFGA
HHHHHHCCCCEEEECCCHHHHHCCEECCCCHHHHHHHEEEEECCCCCCEEEEEEECCCCC
GNYGMCGRAYSPRFLWMWPNARISVMGGEQAASVLATVKRDNFDRKGEAWSDEDEAAFKA
CCCCCCCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
PIREMYEEQGHPYYATARLWDDGVIDPADTRNVLALALSAAHNAPIEETKFGVFRM
HHHHHHHHCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9387222 [H]