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The map label for this gene is ubiC

Identifier: 93005148

GI number: 93005148

Start: 385090

End: 385596

Strand: Direct

Name: ubiC

Synonym: Pcryo_0317

Alternate gene names: 93005148

Gene position: 385090-385596 (Clockwise)

Preceding gene: 93005147

Following gene: 93005149

Centisome position: 12.59

GC content: 44.58

Gene sequence:

>507_bases
ATGATCTCTCATCTTTCTTGCATAACCAATTCATTACCTCCAACTGAGCTATTACCTTGGCTAAATATCGAAGGCTCTCT
TACTGCCTTGCTAGAGGTAAAAGCTGGGCGGCCATTACTCGTAGAACGCAGATTTGAGGGCTATCGGTTATTGTCTTTAG
CACAAAAAAAACAATTGGGTATCAAAGGGGCAGCGCTTAGTCATCCACGGCTGGCATGGGTCCGTGAGGTATATCTATAC
GGTAATGACGAGCTACCATGGGTACAGGCGCAAAGCCTGTTTCCGTTATCAAGTCTAAAAGGCAGTGCCAGACGTCTACA
GCAATTAAAAAGCACACCCATAGGCTATGTATTGTTTAATCGCAGTCGTACCTTGCCCAATCAGCGCTCTATCAAACATA
CGGCAGATGGCTGGCAACGGCAGACGCTTTATGATTGGCATGGTCGTTCTTTACTTATTAGTGAGACCTTTTTGCCACGG
TTCTGTGAAAAACAATTGGATATTTAA

Upstream 100 bases:

>100_bases
TTGCCGTTTAATATTGATAATATGCCAATGTTTGATAACAATGAATAACCTTATCTTTTAACCATATTCTACTTAATAAA
GTACACATTAGCCGTAAACT

Downstream 100 bases:

>100_bases
GTACTTCATCAGAAAATTAAAACAACCAATTAATTAGCCAACTATTTTCCACTTTATTATTCAGATAAGTTTTTAGTGAA
TAAATTTTAATGAATTTACT

Product: chorismate lyase

Products: NA

Alternate protein names: CL; CPL

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MISHLSCITNSLPPTELLPWLNIEGSLTALLEVKAGRPLLVERRFEGYRLLSLAQKKQLGIKGAALSHPRLAWVREVYLY
GNDELPWVQAQSLFPLSSLKGSARRLQQLKSTPIGYVLFNRSRTLPNQRSIKHTADGWQRQTLYDWHGRSLLISETFLPR
FCEKQLDI

Sequences:

>Translated_168_residues
MISHLSCITNSLPPTELLPWLNIEGSLTALLEVKAGRPLLVERRFEGYRLLSLAQKKQLGIKGAALSHPRLAWVREVYLY
GNDELPWVQAQSLFPLSSLKGSARRLQQLKSTPIGYVLFNRSRTLPNQRSIKHTADGWQRQTLYDWHGRSLLISETFLPR
FCEKQLDI
>Mature_168_residues
MISHLSCITNSLPPTELLPWLNIEGSLTALLEVKAGRPLLVERRFEGYRLLSLAQKKQLGIKGAALSHPRLAWVREVYLY
GNDELPWVQAQSLFPLSSLKGSARRLQQLKSTPIGYVLFNRSRTLPNQRSIKHTADGWQRQTLYDWHGRSLLISETFLPR
FCEKQLDI

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family

Homologues:

Organism=Escherichia coli, GI87082361, Length=144, Percent_Identity=30.5555555555556, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIC_PSYCK (Q1QE02)

Other databases:

- EMBL:   CP000323
- RefSeq:   YP_579585.1
- ProteinModelPortal:   Q1QE02
- SMR:   Q1QE02
- STRING:   Q1QE02
- GeneID:   4034080
- GenomeReviews:   CP000323_GR
- KEGG:   pcr:Pcryo_0317
- NMPDR:   fig|335284.3.peg.1006
- eggNOG:   COG3161
- HOGENOM:   HBG289129
- OMA:   ISETFLP
- ProtClustDB:   CLSK2768268
- BioCyc:   PCRY335284:PCRYO_0317-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01632
- InterPro:   IPR007440

Pfam domain/function: PF04345 Chor_lyase

EC number: =4.1.3.40

Molecular weight: Translated: 19265; Mature: 19265

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: NA

Important sites: BINDING 75-75 BINDING 114-114

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISHLSCITNSLPPTELLPWLNIEGSLTALLEVKAGRPLLVERRFEGYRLLSLAQKKQLG
CCCCHHHHHCCCCHHHCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCC
IKGAALSHPRLAWVREVYLYGNDELPWVQAQSLFPLSSLKGSARRLQQLKSTPIGYVLFN
CCCCCCCCCHHHEEEEEEEECCCCCCEEECCCCCCHHHCCHHHHHHHHHHCCCCEEEEEE
RSRTLPNQRSIKHTADGWQRQTLYDWHGRSLLISETFLPRFCEKQLDI
CCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEHHHHHHHHHHHCCC
>Mature Secondary Structure
MISHLSCITNSLPPTELLPWLNIEGSLTALLEVKAGRPLLVERRFEGYRLLSLAQKKQLG
CCCCHHHHHCCCCHHHCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHCC
IKGAALSHPRLAWVREVYLYGNDELPWVQAQSLFPLSSLKGSARRLQQLKSTPIGYVLFN
CCCCCCCCCHHHEEEEEEEECCCCCCEEECCCCCCHHHCCHHHHHHHHHHCCCCEEEEEE
RSRTLPNQRSIKHTADGWQRQTLYDWHGRSLLISETFLPRFCEKQLDI
CCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA