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The map label for this gene is prc [H]

Identifier: 93005140

GI number: 93005140

Start: 372011

End: 374224

Strand: Direct

Name: prc [H]

Synonym: Pcryo_0309

Alternate gene names: 93005140

Gene position: 372011-374224 (Clockwise)

Preceding gene: 93005138

Following gene: 93005142

Centisome position: 12.16

GC content: 44.26

Gene sequence:

>2214_bases
ATGATGAAAAAACAACCAGCACAGTGGTTACTCAGTGCAGCGTCAGTGGGCATCGCAGGTTTAATTCTTACCCAGAGCTA
CGGCACTGCAGTAGCTGATACCAATACCGAAGGTTTTAAACAGACGCCTGAGCAACAGGTTACCACGCGCCAAGTAGCGG
CATTGCTGGATCGCAGTCATTATCTTAATCAGCCACTGGATACAGCGACTGGTAGCGAGATTTTGTCTATGTATATCGAT
AGTCTCGATCCAAACCATACGTTGTTTTTGCAATCTGATGTTGATGAGTTTAAGAAAAAGTATGCCGATGAATTTGGTGC
GCGTTTAAAGCGTGGTGATTTGTCTACTGGGGTAGAAGTATTTGAGCGCTATCGTAAACGCTCAAATGAGTATTTTGCCA
TGGCAAAAAAGATGCTAAAAACGGATATCAATTTGACCAGCAAGGATAACATTGTCCTTGACCGTGAAAAACTCAATCAT
TTTAAAACCAAAAAAGAGCAGCGCGACTATTGGGCAAGTCAGTTAAAGTTTCAGTTGATGAGTATTACTTTGGGTAAGGA
AGATGAAAAAGCAAAAGAAAAAGTCTTTTTAGACAACCCAGATATCACGCGTGGTCAAGATTTGGTCCGTAATGATGAGC
GCACGCCAAGTGAGATTTTACTAAACCGATTGTCTCGTCAGCAAGAGCAGTTTACCCGTCTCAAAGATGATGAGATTATG
GAAACCATCTTAAACACGGCGATGCTGACCTACGATCCTCACAGTAATTATTACGCGCCAATTCAAGCCAATGAGCTGCA
AATACAATCTAGCCTACAGTTAGAAGGGATTGGGGTATCTATCCGCCCTGACCGCAAAAACCCAGACTATACCCGTATTG
TTACCTTAGTCGATGGCGGTCCGGCAGCAAAATCCGGTCAAATTAAGCCCAACGATTTAATTATTGGTATTGCCAAAGAC
GGCGAGACCATGACCGATGTGGTTGGTTGGTCAACGCGAGAAATCGTCAGTCTGATTCGTGGTAAGCGCGGTACATCGGT
GACGATTAAAGTTCGTCAGCCTAATACCCCTGATGCCAGCGCCCGTAATGTAACCGTGGTTCGAGATATTATTGCACAAG
AAGAATCAGGCGTCACTCAGCGTGTTGTTGAAGTTCAGCGTCCAAATATCGATAAAACTCCGAAACGTATCGGTGTTCTT
GAAATACCAAGCTTTTATTTGAACTACCGAGCCCGCCGTAATGGTGAGGATTATCGTAGTGTCAGTATCGATACCGAAAA
AGCATTGAAAGAGTTAAATAAAAAGAATATCGATGGCTTGGTCGTTGATTTGCGCAATAATCCAGGTGGCTCACTAGATG
AAGTTGCCAAGATGCTTGGCTTCTTTATTAAGAGTGGTCCGCTAGTACAGATTCGTGATAATCGTGGCAATATTCAAGTC
TACCGTGATGATGACGGTGGTGAGCAGCTATATGATGGTAAGGTAGTCGTTTTGACCAATCTTGCATCTGCGTCAGCAAG
TGAGATTTTTGCTGCCGCTATCCAAGACTATGGACGTGGCTTGATAGTCGGTAGTACTACAACAGGTAAAGGCTCAGCGC
AAATCCAATTAGACAGCTTGGCGCTTGGTTCTGCGACATTAACGCAGCGTAAATTCTATCGTATCACCGGTGGTAGTACG
CAGAATAAAGGCGTGGTCCCTGATATTGAATTGGTCAACATCTATGACGATGCAACCTTTGGCGAGCGCGCACAGAAAAA
GGCGCTGCCTTGGGATACAATTAAGACTGCACCGTATAAGCCTGAAGGTAACTTCACGTCGAATACCTTGGCGACGCTAA
ACCAACAGTCGAAAATCCGCCAACAAAAAAATCCGCAGTTCGTTTATTTATCAACGCTCAATGATATCCGTAATATGGAA
GATGAGAAAAAACCAGTTGCGCTCGATATCAATAAACGCCGTGCCAAAATGCAGCTAATAGAAAAACGCTCCCTAGAGGC
TGAGAACAAGCGTCAGATTGCAACTGGTGAGCGTCCTTATGCCAACTGGAATACTTATCAAGCGGCAATGGATGCAAAGT
TTGAAGAGCGCAGTCAGATGAAGGCTGCTGAACGTCCAGAGCTACTAGAAGATGAAGCTTTCATTAATGAAGCGGCTTAT
ATTATGCTCAGTGCTGAGCCAACAAAGCTGAGCAGTCCTGAAGAAAAGCTATAA

Upstream 100 bases:

>100_bases
GAGAGTAAAAATAGCTAGCTTTTATGGACAGCCATTTATAGATATTTTTTGATTTTGCTAAAAACAGAGCATACTTTTCA
CTTAAAATAATTAGGTAGAT

Downstream 100 bases:

>100_bases
AAATTATTGTAAACTATTATCTATTCAGCTGCCCAAACTCTACGAAAAATACACGTAAGCATATGCTTACAAGGATTGAC
GTTTAGACCTCTTACTTAGT

Product: carboxyl-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; Protease Re [H]

Number of amino acids: Translated: 737; Mature: 737

Protein sequence:

>737_residues
MMKKQPAQWLLSAASVGIAGLILTQSYGTAVADTNTEGFKQTPEQQVTTRQVAALLDRSHYLNQPLDTATGSEILSMYID
SLDPNHTLFLQSDVDEFKKKYADEFGARLKRGDLSTGVEVFERYRKRSNEYFAMAKKMLKTDINLTSKDNIVLDREKLNH
FKTKKEQRDYWASQLKFQLMSITLGKEDEKAKEKVFLDNPDITRGQDLVRNDERTPSEILLNRLSRQQEQFTRLKDDEIM
ETILNTAMLTYDPHSNYYAPIQANELQIQSSLQLEGIGVSIRPDRKNPDYTRIVTLVDGGPAAKSGQIKPNDLIIGIAKD
GETMTDVVGWSTREIVSLIRGKRGTSVTIKVRQPNTPDASARNVTVVRDIIAQEESGVTQRVVEVQRPNIDKTPKRIGVL
EIPSFYLNYRARRNGEDYRSVSIDTEKALKELNKKNIDGLVVDLRNNPGGSLDEVAKMLGFFIKSGPLVQIRDNRGNIQV
YRDDDGGEQLYDGKVVVLTNLASASASEIFAAAIQDYGRGLIVGSTTTGKGSAQIQLDSLALGSATLTQRKFYRITGGST
QNKGVVPDIELVNIYDDATFGERAQKKALPWDTIKTAPYKPEGNFTSNTLATLNQQSKIRQQKNPQFVYLSTLNDIRNME
DEKKPVALDINKRRAKMQLIEKRSLEAENKRQIATGERPYANWNTYQAAMDAKFEERSQMKAAERPELLEDEAFINEAAY
IMLSAEPTKLSSPEEKL

Sequences:

>Translated_737_residues
MMKKQPAQWLLSAASVGIAGLILTQSYGTAVADTNTEGFKQTPEQQVTTRQVAALLDRSHYLNQPLDTATGSEILSMYID
SLDPNHTLFLQSDVDEFKKKYADEFGARLKRGDLSTGVEVFERYRKRSNEYFAMAKKMLKTDINLTSKDNIVLDREKLNH
FKTKKEQRDYWASQLKFQLMSITLGKEDEKAKEKVFLDNPDITRGQDLVRNDERTPSEILLNRLSRQQEQFTRLKDDEIM
ETILNTAMLTYDPHSNYYAPIQANELQIQSSLQLEGIGVSIRPDRKNPDYTRIVTLVDGGPAAKSGQIKPNDLIIGIAKD
GETMTDVVGWSTREIVSLIRGKRGTSVTIKVRQPNTPDASARNVTVVRDIIAQEESGVTQRVVEVQRPNIDKTPKRIGVL
EIPSFYLNYRARRNGEDYRSVSIDTEKALKELNKKNIDGLVVDLRNNPGGSLDEVAKMLGFFIKSGPLVQIRDNRGNIQV
YRDDDGGEQLYDGKVVVLTNLASASASEIFAAAIQDYGRGLIVGSTTTGKGSAQIQLDSLALGSATLTQRKFYRITGGST
QNKGVVPDIELVNIYDDATFGERAQKKALPWDTIKTAPYKPEGNFTSNTLATLNQQSKIRQQKNPQFVYLSTLNDIRNME
DEKKPVALDINKRRAKMQLIEKRSLEAENKRQIATGERPYANWNTYQAAMDAKFEERSQMKAAERPELLEDEAFINEAAY
IMLSAEPTKLSSPEEKL
>Mature_737_residues
MMKKQPAQWLLSAASVGIAGLILTQSYGTAVADTNTEGFKQTPEQQVTTRQVAALLDRSHYLNQPLDTATGSEILSMYID
SLDPNHTLFLQSDVDEFKKKYADEFGARLKRGDLSTGVEVFERYRKRSNEYFAMAKKMLKTDINLTSKDNIVLDREKLNH
FKTKKEQRDYWASQLKFQLMSITLGKEDEKAKEKVFLDNPDITRGQDLVRNDERTPSEILLNRLSRQQEQFTRLKDDEIM
ETILNTAMLTYDPHSNYYAPIQANELQIQSSLQLEGIGVSIRPDRKNPDYTRIVTLVDGGPAAKSGQIKPNDLIIGIAKD
GETMTDVVGWSTREIVSLIRGKRGTSVTIKVRQPNTPDASARNVTVVRDIIAQEESGVTQRVVEVQRPNIDKTPKRIGVL
EIPSFYLNYRARRNGEDYRSVSIDTEKALKELNKKNIDGLVVDLRNNPGGSLDEVAKMLGFFIKSGPLVQIRDNRGNIQV
YRDDDGGEQLYDGKVVVLTNLASASASEIFAAAIQDYGRGLIVGSTTTGKGSAQIQLDSLALGSATLTQRKFYRITGGST
QNKGVVPDIELVNIYDDATFGERAQKKALPWDTIKTAPYKPEGNFTSNTLATLNQQSKIRQQKNPQFVYLSTLNDIRNME
DEKKPVALDINKRRAKMQLIEKRSLEAENKRQIATGERPYANWNTYQAAMDAKFEERSQMKAAERPELLEDEAFINEAAY
IMLSAEPTKLSSPEEKL

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=656, Percent_Identity=34.2987804878049, Blast_Score=329, Evalue=3e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 82892; Mature: 82892

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKKQPAQWLLSAASVGIAGLILTQSYGTAVADTNTEGFKQTPEQQVTTRQVAALLDRSH
CCCCCHHHHHHHHHHHCCEEEEEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
YLNQPLDTATGSEILSMYIDSLDPNHTLFLQSDVDEFKKKYADEFGARLKRGDLSTGVEV
HHCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHH
FERYRKRSNEYFAMAKKMLKTDINLTSKDNIVLDREKLNHFKTKKEQRDYWASQLKFQLM
HHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHEEEE
SITLGKEDEKAKEKVFLDNPDITRGQDLVRNDERTPSEILLNRLSRQQEQFTRLKDDEIM
EEEECCCCHHHHHCEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHH
ETILNTAMLTYDPHSNYYAPIQANELQIQSSLQLEGIGVSIRPDRKNPDYTRIVTLVDGG
HHHHHHEEEEECCCCCEECCEECCCEEEECCCEEEEEEEEECCCCCCCCCEEEEEEECCC
PAAKSGQIKPNDLIIGIAKDGETMTDVVGWSTREIVSLIRGKRGTSVTIKVRQPNTPDAS
CCCCCCCCCCCCEEEEEECCCCHHHHHHCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCC
ARNVTVVRDIIAQEESGVTQRVVEVQRPNIDKTPKRIGVLEIPSFYLNYRARRNGEDYRS
CCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHEEEEECCHHHHHHHHHCCCCCCEE
VSIDTEKALKELNKKNIDGLVVDLRNNPGGSLDEVAKMLGFFIKSGPLVQIRDNRGNIQV
EECCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEE
YRDDDGGEQLYDGKVVVLTNLASASASEIFAAAIQDYGRGLIVGSTTTGKGSAQIQLDSL
EECCCCCCEEECCEEEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECE
ALGSATLTQRKFYRITGGSTQNKGVVPDIELVNIYDDATFGERAQKKALPWDTIKTAPYK
ECCCHHHCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCC
PEGNFTSNTLATLNQQSKIRQQKNPQFVYLSTLNDIRNMEDEKKPVALDINKRRAKMQLI
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCCCCCEEEECHHHHHHHHHH
EKRSLEAENKRQIATGERPYANWNTYQAAMDAKFEERSQMKAAERPELLEDEAFINEAAY
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCEEE
IMLSAEPTKLSSPEEKL
EEEECCCCCCCCCCCCC
>Mature Secondary Structure
MMKKQPAQWLLSAASVGIAGLILTQSYGTAVADTNTEGFKQTPEQQVTTRQVAALLDRSH
CCCCCHHHHHHHHHHHCCEEEEEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
YLNQPLDTATGSEILSMYIDSLDPNHTLFLQSDVDEFKKKYADEFGARLKRGDLSTGVEV
HHCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHH
FERYRKRSNEYFAMAKKMLKTDINLTSKDNIVLDREKLNHFKTKKEQRDYWASQLKFQLM
HHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHEEEE
SITLGKEDEKAKEKVFLDNPDITRGQDLVRNDERTPSEILLNRLSRQQEQFTRLKDDEIM
EEEECCCCHHHHHCEEECCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHH
ETILNTAMLTYDPHSNYYAPIQANELQIQSSLQLEGIGVSIRPDRKNPDYTRIVTLVDGG
HHHHHHEEEEECCCCCEECCEECCCEEEECCCEEEEEEEEECCCCCCCCCEEEEEEECCC
PAAKSGQIKPNDLIIGIAKDGETMTDVVGWSTREIVSLIRGKRGTSVTIKVRQPNTPDAS
CCCCCCCCCCCCEEEEEECCCCHHHHHHCCCHHHHHHHHCCCCCCEEEEEEECCCCCCCC
ARNVTVVRDIIAQEESGVTQRVVEVQRPNIDKTPKRIGVLEIPSFYLNYRARRNGEDYRS
CCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHEEEEECCHHHHHHHHHCCCCCCEE
VSIDTEKALKELNKKNIDGLVVDLRNNPGGSLDEVAKMLGFFIKSGPLVQIRDNRGNIQV
EECCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEE
YRDDDGGEQLYDGKVVVLTNLASASASEIFAAAIQDYGRGLIVGSTTTGKGSAQIQLDSL
EECCCCCCEEECCEEEEEEECCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEECE
ALGSATLTQRKFYRITGGSTQNKGVVPDIELVNIYDDATFGERAQKKALPWDTIKTAPYK
ECCCHHHCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCCCCCCCCC
PEGNFTSNTLATLNQQSKIRQQKNPQFVYLSTLNDIRNMEDEKKPVALDINKRRAKMQLI
CCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCCCCCEEEECHHHHHHHHHH
EKRSLEAENKRQIATGERPYANWNTYQAAMDAKFEERSQMKAAERPELLEDEAFINEAAY
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCEEE
IMLSAEPTKLSSPEEKL
EEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]