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The map label for this gene is hmp [H]

Identifier: 93004974

GI number: 93004974

Start: 166882

End: 168192

Strand: Reverse

Name: hmp [H]

Synonym: Pcryo_0143

Alternate gene names: 93004974

Gene position: 168192-166882 (Counterclockwise)

Preceding gene: 93004976

Following gene: 93004973

Centisome position: 5.5

GC content: 42.11

Gene sequence:

>1311_bases
ATGACGACTGGCTATCGCCCTGAACTAATCCAACGCGTGTTTATTGATTTCATCAGTACGCGGCTGCACCCCTTTTGGTC
ATTAACTGTGCCTAAATTGCGTCTTATAGCACGCCGTACACTCAGTAATGACTTGATAGCGCTACAATTTGAGCCTAACC
GCGCCTTTAAGCAGCAAGCTTTTAGTTCAGGTAATAGCTCACACAATGGTTGGCATGGCGGACAGCATATTAATTTAAGC
ATACTGATTGATGGTGTTTATCATCAACGCCACTATTCATTGGTTGGTCTAGCGCAGCAACCATTATGGTGGCATGAGGA
CGGCGATAAAAATTCTAATCGAAATCAAGATAGCCTTGATAAAAACGGCTTTGATAGAGATCGCCTTGATGAAAAGTCGC
AACCGCAAACTATTGTCTCTACGATAACTATTGCTGTTAAGCCGCAAGGTCTAGTATCAGATTATCTAAGTAAACGTGCA
GCACTGGGTGTTATATTTAATAGCAGTTTACCCAGTGGCGAATTTACTCTAGCTCATACAGCGTTAGCACAGCAAGCAAG
TCAAATAAGCGAACCCTTATCCCTTACCTCTACACCACTGCCACTATTGTTCATCGCTAGCGGCAGTGGTATTACGCCAA
TGCTAGGTTTGATTACGCAGGCGCTGCAAAATGGACATCCAGTAACGCTGCTACATTACAATTGTACAACCTTCTATAAG
TCCCCATTGCAAGATCAATGGCAGCAGTTAGCTACTAAATATCCAACGTTCATTTATCATCTTATTAATACGGAAGACCC
CAATACTTATCTTGCCGGCTCGCGACATTTGAGCGTAGAAACTTTAATAGCATTAAAATTACCGCTGATGGATACACAGA
TATTTGCCTGTGGTTCGCCGGCGTTGTTAGCGGGTTTGTACCGCGCTTGCGATGAGATTAATTTGCCAGATAACAAGCAG
CTGTGTGACAACATTACGATAGAGAGCTTTAGTGCCATAGAAAGCTTAGATTATATGTTTTCTACTATAGATAAAGCAGA
CGAAGAAGCCGTTACTAGCGAAGAAAAAACCATTTATTTACGTGGACGGCAACGACAATATAACAGTAGTACGACATTAC
TATTAGGTGCTGAGAGCGCTGGTATTCGAATGAGCCACGGCTGCAGACAAGGTATCTGTCAGCTGTGTCGCTGTAATAAG
ATCAGCGGTAGAGTCAAAAACATTCAAACCGGTAAGATAAGTAATGATGGATATGAGTCTATTCAAACCTGCATTAATGT
ACCAATGACTGATGTCATATTGGATATTTAA

Upstream 100 bases:

>100_bases
CAGCATTAAACATTTCGCAAAATTAATCAATAGACGATATTATATTAGCTAATCTTAATAAAATAGCTTTGTAAAAACGG
CTTGATAGAAAAGGTACTCC

Downstream 100 bases:

>100_bases
AAAATACTATCAAGGATAAGACAGCCTTGCATAAACATTTATTTGTAATGTTTATTAAAACTGACACCGATGATTAAACC
GAACGTTGTGCTTACGATTT

Product: oxidoreductase FAD/NAD(P)-binding

Products: NA

Alternate protein names: Rieske-type oxygenase; RO [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MTTGYRPELIQRVFIDFISTRLHPFWSLTVPKLRLIARRTLSNDLIALQFEPNRAFKQQAFSSGNSSHNGWHGGQHINLS
ILIDGVYHQRHYSLVGLAQQPLWWHEDGDKNSNRNQDSLDKNGFDRDRLDEKSQPQTIVSTITIAVKPQGLVSDYLSKRA
ALGVIFNSSLPSGEFTLAHTALAQQASQISEPLSLTSTPLPLLFIASGSGITPMLGLITQALQNGHPVTLLHYNCTTFYK
SPLQDQWQQLATKYPTFIYHLINTEDPNTYLAGSRHLSVETLIALKLPLMDTQIFACGSPALLAGLYRACDEINLPDNKQ
LCDNITIESFSAIESLDYMFSTIDKADEEAVTSEEKTIYLRGRQRQYNSSTTLLLGAESAGIRMSHGCRQGICQLCRCNK
ISGRVKNIQTGKISNDGYESIQTCINVPMTDVILDI

Sequences:

>Translated_436_residues
MTTGYRPELIQRVFIDFISTRLHPFWSLTVPKLRLIARRTLSNDLIALQFEPNRAFKQQAFSSGNSSHNGWHGGQHINLS
ILIDGVYHQRHYSLVGLAQQPLWWHEDGDKNSNRNQDSLDKNGFDRDRLDEKSQPQTIVSTITIAVKPQGLVSDYLSKRA
ALGVIFNSSLPSGEFTLAHTALAQQASQISEPLSLTSTPLPLLFIASGSGITPMLGLITQALQNGHPVTLLHYNCTTFYK
SPLQDQWQQLATKYPTFIYHLINTEDPNTYLAGSRHLSVETLIALKLPLMDTQIFACGSPALLAGLYRACDEINLPDNKQ
LCDNITIESFSAIESLDYMFSTIDKADEEAVTSEEKTIYLRGRQRQYNSSTTLLLGAESAGIRMSHGCRQGICQLCRCNK
ISGRVKNIQTGKISNDGYESIQTCINVPMTDVILDI
>Mature_435_residues
TTGYRPELIQRVFIDFISTRLHPFWSLTVPKLRLIARRTLSNDLIALQFEPNRAFKQQAFSSGNSSHNGWHGGQHINLSI
LIDGVYHQRHYSLVGLAQQPLWWHEDGDKNSNRNQDSLDKNGFDRDRLDEKSQPQTIVSTITIAVKPQGLVSDYLSKRAA
LGVIFNSSLPSGEFTLAHTALAQQASQISEPLSLTSTPLPLLFIASGSGITPMLGLITQALQNGHPVTLLHYNCTTFYKS
PLQDQWQQLATKYPTFIYHLINTEDPNTYLAGSRHLSVETLIALKLPLMDTQIFACGSPALLAGLYRACDEINLPDNKQL
CDNITIESFSAIESLDYMFSTIDKADEEAVTSEEKTIYLRGRQRQYNSSTTLLLGAESAGIRMSHGCRQGICQLCRCNKI
SGRVKNIQTGKISNDGYESIQTCINVPMTDVILDI

Specific function: Catalyzes the opening of ring B of 1,4-androstadiene- 3,17,-dione (ADD) and 4-androstene-3,17-dione (ADD) with concomitant aromatization of ring A. The ring B is subsequently hydroxylated to yield a catechol and then subject to meta- cleavage [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 48621; Mature: 48490

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTGYRPELIQRVFIDFISTRLHPFWSLTVPKLRLIARRTLSNDLIALQFEPNRAFKQQA
CCCCCCHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
FSSGNSSHNGWHGGQHINLSILIDGVYHQRHYSLVGLAQQPLWWHEDGDKNSNRNQDSLD
HHCCCCCCCCCCCCCEEEEEEEEECHHHHHHHHEEECCCCCCEECCCCCCCCCCCCCCCC
KNGFDRDRLDEKSQPQTIVSTITIAVKPQGLVSDYLSKRAALGVIFNSSLPSGEFTLAHT
CCCCCHHHCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHEEEEEEECCCCCCCEEHHHH
ALAQQASQISEPLSLTSTPLPLLFIASGSGITPMLGLITQALQNGHPVTLLHYNCTTFYK
HHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHC
SPLQDQWQQLATKYPTFIYHLINTEDPNTYLAGSRHLSVETLIALKLPLMDTQIFACGSP
CHHHHHHHHHHHHCCEEEEEEECCCCCCEEECCCCCCCCEEEEEEECCCCCCEEEECCCH
ALLAGLYRACDEINLPDNKQLCDNITIESFSAIESLDYMFSTIDKADEEAVTSEEKTIYL
HHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCEEEE
RGRQRQYNSSTTLLLGAESAGIRMSHGCRQGICQLCRCNKISGRVKNIQTGKISNDGYES
ECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCHHHH
IQTCINVPMTDVILDI
HHHHHCCCHHHHEECC
>Mature Secondary Structure 
TTGYRPELIQRVFIDFISTRLHPFWSLTVPKLRLIARRTLSNDLIALQFEPNRAFKQQA
CCCCCHHHHHHHHHHHHHHHCCCCEECCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
FSSGNSSHNGWHGGQHINLSILIDGVYHQRHYSLVGLAQQPLWWHEDGDKNSNRNQDSLD
HHCCCCCCCCCCCCCEEEEEEEEECHHHHHHHHEEECCCCCCEECCCCCCCCCCCCCCCC
KNGFDRDRLDEKSQPQTIVSTITIAVKPQGLVSDYLSKRAALGVIFNSSLPSGEFTLAHT
CCCCCHHHCCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHEEEEEEECCCCCCCEEHHHH
ALAQQASQISEPLSLTSTPLPLLFIASGSGITPMLGLITQALQNGHPVTLLHYNCTTFYK
HHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHC
SPLQDQWQQLATKYPTFIYHLINTEDPNTYLAGSRHLSVETLIALKLPLMDTQIFACGSP
CHHHHHHHHHHHHCCEEEEEEECCCCCCEEECCCCCCCCEEEEEEECCCCCCEEEECCCH
ALLAGLYRACDEINLPDNKQLCDNITIESFSAIESLDYMFSTIDKADEEAVTSEEKTIYL
HHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCEEEE
RGRQRQYNSSTTLLLGAESAGIRMSHGCRQGICQLCRCNKISGRVKNIQTGKISNDGYES
ECCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEECCCCCCCHHHH
IQTCINVPMTDVILDI
HHHHHCCCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]