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The map label for this gene is 93004971

Identifier: 93004971

GI number: 93004971

Start: 164331

End: 164624

Strand: Reverse

Name: 93004971

Synonym: Pcryo_0140

Alternate gene names: NA

Gene position: 164624-164331 (Counterclockwise)

Preceding gene: 93004972

Following gene: 93004969

Centisome position: 5.38

GC content: 42.52

Gene sequence:

>294_bases
ATGAGTAGTTTATCTAATCAACAAGTCGATTTGCAGTTAGAAGAATTACCAGGCTGGCAGCGCGAAGGTAATGCGATCGT
AAAAACTTACCATTTTGGCGATTTTGTTGAAGCTATGAGCTTTATGAATCAAGCTGCTTTTCATGCTGAGGCCTTAGAAC
ATCATCCTGAATGGAGTAATACCTATAATGTGGTAGAAGTTCGCCTGACTACGGGCGATACTGGCGGCATCACCAGTCAT
GATGTTCGTTTAGCAAAACGCATGGAACATATCGTCCAGCGCAAACGCTTATAA

Upstream 100 bases:

>100_bases
TATTACATTCGTGAAGGCAAATAAAAATTACAGTAGTTGCCACACTATTTTATCGTTAATAATGATTTTTCTATCAACCA
TAATAATAAAGGATATCACC

Downstream 100 bases:

>100_bases
ATATCAAGCTGTGCGCTTACTACTTATCACTTAGCAGATAGCTATGTTCTAGCCATAAAAAAAGACCTCAGATAGTATCT
GAGGTCTTTTTTACTAGCCA

Product: transcriptional coactivator/pterin dehydratase

Products: NA

Alternate protein names: PHS; 4-alpha-hydroxy-tetrahydropterin dehydratase; Pterin carbinolamine dehydratase; PCD [H]

Number of amino acids: Translated: 97; Mature: 96

Protein sequence:

>97_residues
MSSLSNQQVDLQLEELPGWQREGNAIVKTYHFGDFVEAMSFMNQAAFHAEALEHHPEWSNTYNVVEVRLTTGDTGGITSH
DVRLAKRMEHIVQRKRL

Sequences:

>Translated_97_residues
MSSLSNQQVDLQLEELPGWQREGNAIVKTYHFGDFVEAMSFMNQAAFHAEALEHHPEWSNTYNVVEVRLTTGDTGGITSH
DVRLAKRMEHIVQRKRL
>Mature_96_residues
SSLSNQQVDLQLEELPGWQREGNAIVKTYHFGDFVEAMSFMNQAAFHAEALEHHPEWSNTYNVVEVRLTTGDTGGITSHD
VRLAKRMEHIVQRKRL

Specific function: Unknown

COG id: COG2154

COG function: function code H; Pterin-4a-carbinolamine dehydratase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pterin-4-alpha-carbinolamine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI4557831, Length=93, Percent_Identity=41.9354838709677, Blast_Score=73, Evalue=6e-14,
Organism=Homo sapiens, GI134133240, Length=75, Percent_Identity=45.3333333333333, Blast_Score=73, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI115533705, Length=79, Percent_Identity=48.1012658227848, Blast_Score=82, Evalue=7e-17,
Organism=Drosophila melanogaster, GI45549100, Length=74, Percent_Identity=48.6486486486487, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001533 [H]

Pfam domain/function: PF01329 Pterin_4a [H]

EC number: =4.2.1.96 [H]

Molecular weight: Translated: 11138; Mature: 11006

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLSNQQVDLQLEELPGWQREGNAIVKTYHFGDFVEAMSFMNQAAFHAEALEHHPEWSN
CCCCCCCCEEEEHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TYNVVEVRLTTGDTGGITSHDVRLAKRMEHIVQRKRL
CEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSLSNQQVDLQLEELPGWQREGNAIVKTYHFGDFVEAMSFMNQAAFHAEALEHHPEWSN
CCCCCCCEEEEHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
TYNVVEVRLTTGDTGGITSHDVRLAKRMEHIVQRKRL
CEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA