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The map label for this gene is coaE [H]

Identifier: 93004897

GI number: 93004897

Start: 74775

End: 75467

Strand: Reverse

Name: coaE [H]

Synonym: Pcryo_0066

Alternate gene names: 93004897

Gene position: 75467-74775 (Counterclockwise)

Preceding gene: 93004898

Following gene: 93004894

Centisome position: 2.47

GC content: 47.33

Gene sequence:

>693_bases
ATGTCAAAATACGCAGCAGCACCTTCACCTTATTCTCATCAGCCGCAAACGCCTGAGCATAAAAGTAAAACATTGGTAGT
GGGTTTAACGGGTGGTATCGGCAGTGGCAAATCAGCCGCCAGTGACTGGTTCGCACAGCAGGGAATCGATATTATTGATG
CAGATGTTATTGCACATGAAGTGGTGGTCAAAGGCAGCTCAACGTTGCGCAAGATCCAGAGGAAATTTGGTGATTGGGTG
CTAAACGCCAATGGTGATATGGACCGCGCCGCTGTACGGACCCATGTGTTTACTTATCCTGATGCTCTAATTGAACTTGA
AGCGATTACCCATCCAGCGATACGCGAAGCTGCAAAAAAGCAATTGGCAGAGAGTACCTCGCCGTATGTGGTGTTGTCAG
CGCCGTTATTGATTGAAGCGGCAGAAGCTGGGCTTGCCAATTTATGTCAACGTATTTTGGTGATGGATGCCACAGAAAAT
ACCCAACTTGCACGAGCCAGTCAACGTGATGCGCTAAGTGTGCAAAAAATTGAAGCCATTATGGTCAATCAGCTTAGCCG
TGAAGAGCGCAATCGTCATGCGGATGATGTGGTATTAAATGAGAGTGATCTTGCGGCCCTATATGTACAATTAGAGCCGC
TCCATCAAGACTATCTTAAGCTTGCCCAGCAGCTAAAGTTCGCTGCCGATTAA

Upstream 100 bases:

>100_bases
TAGGTATGTATACTTAAGCAGTAGCCATTTCCCAATAGTTATGTTTAACCTTTCATTGATTACAGTCATTATCCTTCTAT
CAGTCAGATAAGTCATCATT

Downstream 100 bases:

>100_bases
TCTCATACAAAGCCATACCTGTCGCCACACTGACATTCAAGCTTTGCAAGTTGCCATGCTCGTTGCCTGACATCGGAATA
TAAACCAGCTCATCGCAGCT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MSKYAAAPSPYSHQPQTPEHKSKTLVVGLTGGIGSGKSAASDWFAQQGIDIIDADVIAHEVVVKGSSTLRKIQRKFGDWV
LNANGDMDRAAVRTHVFTYPDALIELEAITHPAIREAAKKQLAESTSPYVVLSAPLLIEAAEAGLANLCQRILVMDATEN
TQLARASQRDALSVQKIEAIMVNQLSREERNRHADDVVLNESDLAALYVQLEPLHQDYLKLAQQLKFAAD

Sequences:

>Translated_230_residues
MSKYAAAPSPYSHQPQTPEHKSKTLVVGLTGGIGSGKSAASDWFAQQGIDIIDADVIAHEVVVKGSSTLRKIQRKFGDWV
LNANGDMDRAAVRTHVFTYPDALIELEAITHPAIREAAKKQLAESTSPYVVLSAPLLIEAAEAGLANLCQRILVMDATEN
TQLARASQRDALSVQKIEAIMVNQLSREERNRHADDVVLNESDLAALYVQLEPLHQDYLKLAQQLKFAAD
>Mature_229_residues
SKYAAAPSPYSHQPQTPEHKSKTLVVGLTGGIGSGKSAASDWFAQQGIDIIDADVIAHEVVVKGSSTLRKIQRKFGDWVL
NANGDMDRAAVRTHVFTYPDALIELEAITHPAIREAAKKQLAESTSPYVVLSAPLLIEAAEAGLANLCQRILVMDATENT
QLARASQRDALSVQKIEAIMVNQLSREERNRHADDVVLNESDLAALYVQLEPLHQDYLKLAQQLKFAAD

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=196, Percent_Identity=36.2244897959184, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI191252795, Length=196, Percent_Identity=36.2244897959184, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI205277394, Length=178, Percent_Identity=28.6516853932584, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI110227605, Length=178, Percent_Identity=28.6516853932584, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI110227603, Length=178, Percent_Identity=28.6516853932584, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI110227601, Length=178, Percent_Identity=28.6516853932584, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI110227607, Length=184, Percent_Identity=28.804347826087, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1786292, Length=200, Percent_Identity=41, Blast_Score=139, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17554944, Length=188, Percent_Identity=33.5106382978723, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI25143409, Length=175, Percent_Identity=31.4285714285714, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320402, Length=196, Percent_Identity=35.7142857142857, Blast_Score=93, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24644728, Length=152, Percent_Identity=34.8684210526316, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24658602, Length=187, Percent_Identity=28.8770053475936, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 25124; Mature: 24993

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKYAAAPSPYSHQPQTPEHKSKTLVVGLTGGIGSGKSAASDWFAQQGIDIIDADVIAHE
CCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCEEHHHHHHHH
VVVKGSSTLRKIQRKFGDWVLNANGDMDRAAVRTHVFTYPDALIELEAITHPAIREAAKK
HHCCCHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHEECCHHHEEHHHHCCHHHHHHHHH
QLAESTSPYVVLSAPLLIEAAEAGLANLCQRILVMDATENTQLARASQRDALSVQKIEAI
HHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
MVNQLSREERNRHADDVVLNESDLAALYVQLEPLHQDYLKLAQQLKFAAD
HHHHHHHHHHHCCCCCEEECCCCEEEEEEEECHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKYAAAPSPYSHQPQTPEHKSKTLVVGLTGGIGSGKSAASDWFAQQGIDIIDADVIAHE
CCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCEEHHHHHHHH
VVVKGSSTLRKIQRKFGDWVLNANGDMDRAAVRTHVFTYPDALIELEAITHPAIREAAKK
HHCCCHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHEECCHHHEEHHHHCCHHHHHHHHH
QLAESTSPYVVLSAPLLIEAAEAGLANLCQRILVMDATENTQLARASQRDALSVQKIEAI
HHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
MVNQLSREERNRHADDVVLNESDLAALYVQLEPLHQDYLKLAQQLKFAAD
HHHHHHHHHHHCCCCCEEECCCCEEEEEEEECHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA