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The map label for this gene is erpA

Identifier: 93004875

GI number: 93004875

Start: 52168

End: 52548

Strand: Reverse

Name: erpA

Synonym: Pcryo_0044

Alternate gene names: 93004875

Gene position: 52548-52168 (Counterclockwise)

Preceding gene: 93004877

Following gene: 93004874

Centisome position: 1.72

GC content: 49.08

Gene sequence:

>381_bases
ATGAACCAACCAGCCAACCAATTTAATCCAAGCTCAAGCCAACCTGTCGATCCAACTGTATTGAACCTGACTGACAGTGC
GGCGCAAAAAGTCCGTCGCCTGCGTGAAGAAGAAGGTGATAGCAACTTGATGCTACGCGTCTATGTGACGGGCGGCGGCT
GTTCGGGCTTTTCTTATGGCTTTAACTTCGCCAATGAGCTCAATGAAGATGATGCCAACTTCGATAATAACGATGTGACC
TTGGTCGTTGACTCATTAAGCTATCAATACCTGCAAGGCTCTACCGTTGATTATACCGAAGGCTTGGAAGGCGCACGCTT
TATCGTGACCAACCCTAATGCCACGACCACTTGTGGCTGCGGCTCGTCATTCTCGATCTAA

Upstream 100 bases:

>100_bases
CAGCTATGAAAAGCTACTGGCAAGTCATCTTAGCCTGTATCAATAGACGACCTCGCATACGTAAAAATAATAACATCTGA
TTTTAGCAATTGAGGTAGAT

Downstream 100 bases:

>100_bases
ATACTCGCTTTGGTATATCTTAATATCCAATGACTATATAAAGAATTGTTTTGCTATGGCACTTATCCGATTGGTAGGTG
CTTTTTATTTCAGATATTTT

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MNQPANQFNPSSSQPVDPTVLNLTDSAAQKVRRLREEEGDSNLMLRVYVTGGGCSGFSYGFNFANELNEDDANFDNNDVT
LVVDSLSYQYLQGSTVDYTEGLEGARFIVTNPNATTTCGCGSSFSI

Sequences:

>Translated_126_residues
MNQPANQFNPSSSQPVDPTVLNLTDSAAQKVRRLREEEGDSNLMLRVYVTGGGCSGFSYGFNFANELNEDDANFDNNDVT
LVVDSLSYQYLQGSTVDYTEGLEGARFIVTNPNATTTCGCGSSFSI
>Mature_126_residues
MNQPANQFNPSSSQPVDPTVLNLTDSAAQKVRRLREEEGDSNLMLRVYVTGGGCSGFSYGFNFANELNEDDANFDNNDVT
LVVDSLSYQYLQGSTVDYTEGLEGARFIVTNPNATTTCGCGSSFSI

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI160420328, Length=125, Percent_Identity=38.4, Blast_Score=82, Evalue=1e-16,
Organism=Homo sapiens, GI52426768, Length=117, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786351, Length=106, Percent_Identity=64.1509433962264, Blast_Score=143, Evalue=4e-36,
Organism=Escherichia coli, GI1788877, Length=108, Percent_Identity=40.7407407407407, Blast_Score=74, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71998452, Length=108, Percent_Identity=40.7407407407407, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25146411, Length=106, Percent_Identity=32.0754716981132, Blast_Score=69, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI193209025, Length=106, Percent_Identity=32.0754716981132, Blast_Score=68, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6323001, Length=107, Percent_Identity=28.9719626168224, Blast_Score=65, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24649697, Length=97, Percent_Identity=49.4845360824742, Blast_Score=90, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24642263, Length=106, Percent_Identity=32.0754716981132, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA_PSYA2 (Q4FVP8)

Other databases:

- EMBL:   CP000082
- RefSeq:   YP_263344.1
- HSSP:   O67709
- ProteinModelPortal:   Q4FVP8
- SMR:   Q4FVP8
- STRING:   Q4FVP8
- GeneID:   3514772
- GenomeReviews:   CP000082_GR
- KEGG:   par:Psyc_0036
- eggNOG:   COG0316
- HOGENOM:   HBG730174
- OMA:   TFDDQIN
- PhylomeDB:   Q4FVP8
- ProtClustDB:   PRK13623
- BioCyc:   PARC259536:PSYC_0036-MONOMER
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 13640; Mature: 13640

Theoretical pI: Translated: 3.81; Mature: 3.81

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQPANQFNPSSSQPVDPTVLNLTDSAAQKVRRLREEEGDSNLMLRVYVTGGGCSGFSYG
CCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCC
FNFANELNEDDANFDNNDVTLVVDSLSYQYLQGSTVDYTEGLEGARFIVTNPNATTTCGC
CCCHHHCCCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCEEEEECCCCCEEECC
GSSFSI
CCCCCC
>Mature Secondary Structure
MNQPANQFNPSSSQPVDPTVLNLTDSAAQKVRRLREEEGDSNLMLRVYVTGGGCSGFSYG
CCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCC
FNFANELNEDDANFDNNDVTLVVDSLSYQYLQGSTVDYTEGLEGARFIVTNPNATTTCGC
CCCHHHCCCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCEEEEECCCCCEEECC
GSSFSI
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA