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The map label for this gene is eriC [C]

Identifier: 92115415

GI number: 92115415

Start: 3676307

End: 3678064

Strand: Direct

Name: eriC [C]

Synonym: Csal_3300

Alternate gene names: 92115415

Gene position: 3676307-3678064 (Clockwise)

Preceding gene: 92115393

Following gene: 92115416

Centisome position: 99.45

GC content: 67.12

Gene sequence:

>1758_bases
GTGCCATCGCCCCGCTTTCGCGCCATGTTCAAACGGCCCAGCCTGGAAAGTTTCCGCCGTCGCCTGGCAAGCGTCGATGC
CTTGCCGCAGCTTTGCGTGCTGGGTGTGCTCTCGGGGGTGTTGACCGGCGGCTTGATGGTGGGATTCCGGGGGCTGCTGG
AGCTGGGGGCACTGGCTTTCATGCCGGGCGGCGATCCCGAGGCGTTCGAGCGCCTCGCGGGCCCGGTGCGCGTCGTGCTG
CCGCTGATGGCCGTGGGGCTGATCGGCGTGTGGCTGTGGCGCATGCCGAACGGTGCCGGCAAGATCGGCATCGGCCATGT
CATCGAGCGTCTCACCTACCATCAGGGCAAGATGCCGTTGCGCAACTGGATGACCCAGTGGTGGGTCGGGCTCGTCGCTC
TGCTGGGCGGTCTTTCCGCGGGGCGTGAAGGGCCGGCGATCCATCTCGGCGCGGCGGCTTCGAGCTGGATCGGTCAGACC
ATGCGCCTGCCGCACAACAGTCTCCGGGTACTGGTCGGCTGCGGTACCGCCGCGGGTATCGCGGCCTCGTTCAATACGCC
CATCGCCGGGGTCATCTTCGCCATGGAAGTGGTGATGATGGAGTACACCATCACCGGCTTCATGCCGGTGATTCTCGCGT
CGACCACCGGCGCCGTGGTCTCGCAACTGGTCTACGGTTCGCAGCCCGCCTTCTCGGTGCCCAGCGTGCAACTGGCGTCG
TTGTTCGATCTGCCCTGGATCGCCGTCACGGCGTTGCTGATCGGTCTGGTGGCGGGGGCGTTCGTGCGTCTCGCCAAACC
GGCGACCTGGCAGACGCGCTGGCCGGTATGGGGGCGCTTTCTGGCAGTGGGCCTGGCGGTGGGCGCAGTGGCCTGGTGGT
ATCCCCAGGTGCAAGGCATGGGCTATGACTCGCTGGAGCGCATGCTCGTCGGTGAGCCGGCCCTGGATGTCCTGATCGTC
GTGGCGCTGGGCAAACTGGCGCTGACGGCCCTGGCCATCGCCTTCGGCGTGCCGGTGAGCATCATCGGGCCGATCCTGGT
GGCGGGCGCGGCCTTCGGCACGCTGTGCGGACTGCTGTGGGCGACCCTGCTGCCGGGTCTGGCATCCTCGCCGGTGGTCT
TTTCGTTGCTGGGCATGGCGGCCATGATGGGGGCCGTGCTGCAGGCGCCTCTGGCGGCGCTGATGGCATTGCTGGAACTG
ACCCACAACTCGAGCATCCTGCTGCCGGGCATGCTGGCGGTGGTGATCGCGGTTCTGGTGTCGCGCCAGGGGTATCACTG
CTCGGGGTTCTTCATCTCGACGCTGGACAGCCAGGGACTTCATCCCCTGCAACGCCCCTTGATGCAGGCCCTGTCGCGGG
TCGCGGTACCGGCCGTCATGGAGCGCAGCGTGGCCCGCGCGCCGCGCATACTGACGCGGGCCCAGGCTCAGGAGCTGCTT
GCCGGGAAGCCGACCTGGCTGGTGATCACGCGCGAGGACGGCAAGCCCCCCGTGGGTCTCAAGGCCGCCGGACTGGCACG
CCTGATGCTCGACGAGCAGTGGCAGGACGAGACGCGTTTCGACCTGCTGGAGATTCCCGGCCAGCGGGTCGACATGGCAC
CGATCGCCCTGCAGGCGACGCTCTCCGAAGCCTTCGAACAGCTCAACAAACAGGGGGTCGATGTCCTGTATGTCGAGCAC
ACCACGGCGCCCCTCATCCGCAAGATTTCGGGTATCATCACCCGCGACGCCATCGAGAACTACTACCGTTACAAATGA

Upstream 100 bases:

>100_bases
GAGCATCGCGCCACCGATGGGTGGCGCGCTCACGCTGGGGCCTGGCCGCACCGCTGCCCCTTTGCCCCGGCGGAGATCGA
CCGCTCACAGGGAGATCAGT

Downstream 100 bases:

>100_bases
TCCCCAGCGAGGAATGTCTTCATTCGCGGACGCTGTGTCCGGCGGTGTGGGCAGGGGCTGGCATTGAGGAGTCACCATGT
ATCAATGGATCTTATCGCTG

Product: Cl- channel, voltage gated

Products: Cl Ion [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 584

Protein sequence:

>585_residues
MPSPRFRAMFKRPSLESFRRRLASVDALPQLCVLGVLSGVLTGGLMVGFRGLLELGALAFMPGGDPEAFERLAGPVRVVL
PLMAVGLIGVWLWRMPNGAGKIGIGHVIERLTYHQGKMPLRNWMTQWWVGLVALLGGLSAGREGPAIHLGAAASSWIGQT
MRLPHNSLRVLVGCGTAAGIAASFNTPIAGVIFAMEVVMMEYTITGFMPVILASTTGAVVSQLVYGSQPAFSVPSVQLAS
LFDLPWIAVTALLIGLVAGAFVRLAKPATWQTRWPVWGRFLAVGLAVGAVAWWYPQVQGMGYDSLERMLVGEPALDVLIV
VALGKLALTALAIAFGVPVSIIGPILVAGAAFGTLCGLLWATLLPGLASSPVVFSLLGMAAMMGAVLQAPLAALMALLEL
THNSSILLPGMLAVVIAVLVSRQGYHCSGFFISTLDSQGLHPLQRPLMQALSRVAVPAVMERSVARAPRILTRAQAQELL
AGKPTWLVITREDGKPPVGLKAAGLARLMLDEQWQDETRFDLLEIPGQRVDMAPIALQATLSEAFEQLNKQGVDVLYVEH
TTAPLIRKISGIITRDAIENYYRYK

Sequences:

>Translated_585_residues
MPSPRFRAMFKRPSLESFRRRLASVDALPQLCVLGVLSGVLTGGLMVGFRGLLELGALAFMPGGDPEAFERLAGPVRVVL
PLMAVGLIGVWLWRMPNGAGKIGIGHVIERLTYHQGKMPLRNWMTQWWVGLVALLGGLSAGREGPAIHLGAAASSWIGQT
MRLPHNSLRVLVGCGTAAGIAASFNTPIAGVIFAMEVVMMEYTITGFMPVILASTTGAVVSQLVYGSQPAFSVPSVQLAS
LFDLPWIAVTALLIGLVAGAFVRLAKPATWQTRWPVWGRFLAVGLAVGAVAWWYPQVQGMGYDSLERMLVGEPALDVLIV
VALGKLALTALAIAFGVPVSIIGPILVAGAAFGTLCGLLWATLLPGLASSPVVFSLLGMAAMMGAVLQAPLAALMALLEL
THNSSILLPGMLAVVIAVLVSRQGYHCSGFFISTLDSQGLHPLQRPLMQALSRVAVPAVMERSVARAPRILTRAQAQELL
AGKPTWLVITREDGKPPVGLKAAGLARLMLDEQWQDETRFDLLEIPGQRVDMAPIALQATLSEAFEQLNKQGVDVLYVEH
TTAPLIRKISGIITRDAIENYYRYK
>Mature_584_residues
PSPRFRAMFKRPSLESFRRRLASVDALPQLCVLGVLSGVLTGGLMVGFRGLLELGALAFMPGGDPEAFERLAGPVRVVLP
LMAVGLIGVWLWRMPNGAGKIGIGHVIERLTYHQGKMPLRNWMTQWWVGLVALLGGLSAGREGPAIHLGAAASSWIGQTM
RLPHNSLRVLVGCGTAAGIAASFNTPIAGVIFAMEVVMMEYTITGFMPVILASTTGAVVSQLVYGSQPAFSVPSVQLASL
FDLPWIAVTALLIGLVAGAFVRLAKPATWQTRWPVWGRFLAVGLAVGAVAWWYPQVQGMGYDSLERMLVGEPALDVLIVV
ALGKLALTALAIAFGVPVSIIGPILVAGAAFGTLCGLLWATLLPGLASSPVVFSLLGMAAMMGAVLQAPLAALMALLELT
HNSSILLPGMLAVVIAVLVSRQGYHCSGFFISTLDSQGLHPLQRPLMQALSRVAVPAVMERSVARAPRILTRAQAQELLA
GKPTWLVITREDGKPPVGLKAAGLARLMLDEQWQDETRFDLLEIPGQRVDMAPIALQATLSEAFEQLNKQGVDVLYVEHT
TAPLIRKISGIITRDAIENYYRYK

Specific function: Selective chloride channel [C]

COG id: COG0038

COG function: function code P; Chloride channel protein EriC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786350, Length=301, Percent_Identity=25.9136212624585, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87081943, Length=308, Percent_Identity=30.5194805194805, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014743
- InterPro:   IPR001807 [H]

Pfam domain/function: PF00654 Voltage_CLC [H]

EC number: NA

Molecular weight: Translated: 62533; Mature: 62402

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PSPRFRAMFKRPSLESFRRRLASVDALPQLCVLGVLSGVLTGGLMVGFRGLLELGALAF
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC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HHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Cl Ion [Periplasm] [C]

Specific reaction: Cl Ion [Periplasm] = Cl Ion [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]