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The map label for this gene is pepQ [H]

Identifier: 92115282

GI number: 92115282

Start: 3531484

End: 3532752

Strand: Direct

Name: pepQ [H]

Synonym: Csal_3167

Alternate gene names: 92115282

Gene position: 3531484-3532752 (Clockwise)

Preceding gene: 92115281

Following gene: 92115284

Centisome position: 95.53

GC content: 65.41

Gene sequence:

>1269_bases
ATGGGCGATATCGTTTCACTCGCCGGGTCCGTCCCCACGGGCGGTCCCTACACCGACGGCAGCTTTCGTCACGCCACGCT
GGATGCCGAGCTGCTCTCGCGCGTCGAGCGCTATCGGCTTCAGCGGCTGCGTCAGCAGATGCGTCACCACGAGCTGGACG
CGGTGATCCTGTTCGACCCGATCAACATTCGCTATGCCTGCGGCGTGCGCAACATGCAGGTGTATTCGCAGCGCAACCCG
GCGCGCTACCTTTATGTTGCGGCGGACGGCCCGGTGGTGCTGTTTGAGTTCAGCGCCTGCCTGCATCTGGCAGCCAACGC
CGAACTGCTCGACGAGGTCCGCCCCGCCCGGGCGGTGATGCCGCAATACAGCGGCCCGCGTTGCGCGACGCACACTCAGG
CCTTCGTCGACGACATTCGCGGTCTGTTCGCGCGCTCGCATGCCCAAGGGCAGCGCCTGGGGATCGAATCCGCGCCCACC
GGCGCCATCGAGGCACTGGGCCAGGCCGGCTTCGAACTGACCGACGCCGCCACCGTGGTCGAGGGCGCCAAGTCGATCAA
GAGTGTCGACGAGCTGGCGCTCATCCATCGTTCCGTGACGCTGACCGAAGCCGCGATGACGCACATGGAGGCCGCCCTGC
GCCCCGGCATGAGCGAAAACGAGCTGTGGTCGATCTTCAACCAGCATGTGCTGGCGACCGGTGGCGAATACGCCGAGACC
CGCCTGCTCAGTTCCGGCGCGCGCACCAACCCGTGGTTCCAGGAATGTTCGGACAAGATCATCGCCCCGGGTGAGCTGGT
CGCCTTCGATACCGACATCGTGGGATGCTTCGGCTACTACACCGACTTCTCGCGGACCTTCCACGTGCCCGGCGCAGGTG
CGCCCAATGCCGAGCAGAAAGCGCTGTATCGCATGGCCGCCGACCAGCTCGAGCGCAACATCGCGCTGCTGCGCCCCGGC
ATGAGTTTCCGCGACTACTCGCGCCAGGCATGGCCGATCCCCGACGGCTATCGCGAGAACCGCTACCTGGATATCGTCCA
TGGCTGCGGCATGACCGGCGAATGGCCGTTGATCGCCCACGACATGGACTGGGACGACGTCGGCTACGATGGTGACATCG
AGCCCGGCATGACGCTGTGCGTCGAGGCCTACATCGGCCACCGCGACGGCACCGAGGGCGTCAAGCTGGAAGAGCAGGTG
CTGATCACCGAAGATGGTATCGATCGCCTCTCGACCTACGGCTATTCCGAGACGCTGATGGCAGAATGA

Upstream 100 bases:

>100_bases
CGACGCCGACAATCAGCGCCGCCACGACGCGCTCATGGGCTGACGACACCTCGCACGCGTTTCCCGGCGTTTCGTTCACT
TTCAACCAGGATATCTTTCA

Downstream 100 bases:

>100_bases
CACCATCGCGCAACACTTTTCTCATCCCTTTCGATTCACCAACACAAAAAGGACGCGTTTGACTGCTCCCCGCCCTGAAG
GATGGGGGTTCCCAATTCAC

Product: peptidase M24

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MGDIVSLAGSVPTGGPYTDGSFRHATLDAELLSRVERYRLQRLRQQMRHHELDAVILFDPINIRYACGVRNMQVYSQRNP
ARYLYVAADGPVVLFEFSACLHLAANAELLDEVRPARAVMPQYSGPRCATHTQAFVDDIRGLFARSHAQGQRLGIESAPT
GAIEALGQAGFELTDAATVVEGAKSIKSVDELALIHRSVTLTEAAMTHMEAALRPGMSENELWSIFNQHVLATGGEYAET
RLLSSGARTNPWFQECSDKIIAPGELVAFDTDIVGCFGYYTDFSRTFHVPGAGAPNAEQKALYRMAADQLERNIALLRPG
MSFRDYSRQAWPIPDGYRENRYLDIVHGCGMTGEWPLIAHDMDWDDVGYDGDIEPGMTLCVEAYIGHRDGTEGVKLEEQV
LITEDGIDRLSTYGYSETLMAE

Sequences:

>Translated_422_residues
MGDIVSLAGSVPTGGPYTDGSFRHATLDAELLSRVERYRLQRLRQQMRHHELDAVILFDPINIRYACGVRNMQVYSQRNP
ARYLYVAADGPVVLFEFSACLHLAANAELLDEVRPARAVMPQYSGPRCATHTQAFVDDIRGLFARSHAQGQRLGIESAPT
GAIEALGQAGFELTDAATVVEGAKSIKSVDELALIHRSVTLTEAAMTHMEAALRPGMSENELWSIFNQHVLATGGEYAET
RLLSSGARTNPWFQECSDKIIAPGELVAFDTDIVGCFGYYTDFSRTFHVPGAGAPNAEQKALYRMAADQLERNIALLRPG
MSFRDYSRQAWPIPDGYRENRYLDIVHGCGMTGEWPLIAHDMDWDDVGYDGDIEPGMTLCVEAYIGHRDGTEGVKLEEQV
LITEDGIDRLSTYGYSETLMAE
>Mature_421_residues
GDIVSLAGSVPTGGPYTDGSFRHATLDAELLSRVERYRLQRLRQQMRHHELDAVILFDPINIRYACGVRNMQVYSQRNPA
RYLYVAADGPVVLFEFSACLHLAANAELLDEVRPARAVMPQYSGPRCATHTQAFVDDIRGLFARSHAQGQRLGIESAPTG
AIEALGQAGFELTDAATVVEGAKSIKSVDELALIHRSVTLTEAAMTHMEAALRPGMSENELWSIFNQHVLATGGEYAETR
LLSSGARTNPWFQECSDKIIAPGELVAFDTDIVGCFGYYTDFSRTFHVPGAGAPNAEQKALYRMAADQLERNIALLRPGM
SFRDYSRQAWPIPDGYRENRYLDIVHGCGMTGEWPLIAHDMDWDDVGYDGDIEPGMTLCVEAYIGHRDGTEGVKLEEQVL
ITEDGIDRLSTYGYSETLMAE

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789275, Length=316, Percent_Identity=27.2151898734177, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 46678; Mature: 46547

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDIVSLAGSVPTGGPYTDGSFRHATLDAELLSRVERYRLQRLRQQMRHHELDAVILFDP
CCCHHHHCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
INIRYACGVRNMQVYSQRNPARYLYVAADGPVVLFEFSACLHLAANAELLDEVRPARAVM
CCEEEECCCCCCHHHCCCCCCEEEEEECCCCEEEEEHHHHHHHHCCHHHHHHHCHHHHHC
PQYSGPRCATHTQAFVDDIRGLFARSHAQGQRLGIESAPTGAIEALGQAGFELTDAATVV
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHH
EGAKSIKSVDELALIHRSVTLTEAAMTHMEAALRPGMSENELWSIFNQHVLATGGEYAET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEECCCCHHHH
RLLSSGARTNPWFQECSDKIIAPGELVAFDTDIVGCFGYYTDFSRTFHVPGAGAPNAEQK
HHHHCCCCCCCHHHHHCCCCCCCCCEEEECCHHHHHHHHHHCCCCEEECCCCCCCCHHHH
ALYRMAADQLERNIALLRPGMSFRDYSRQAWPIPDGYRENRYLDIVHGCGMTGEWPLIAH
HHHHHHHHHHHCCCEEECCCCCHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEE
DMDWDDVGYDGDIEPGMTLCVEAYIGHRDGTEGVKLEEQVLITEDGIDRLSTYGYSETLM
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEECCEEEEECCCHHHHHHCCCCHHHC
AE
CC
>Mature Secondary Structure 
GDIVSLAGSVPTGGPYTDGSFRHATLDAELLSRVERYRLQRLRQQMRHHELDAVILFDP
CCHHHHCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
INIRYACGVRNMQVYSQRNPARYLYVAADGPVVLFEFSACLHLAANAELLDEVRPARAVM
CCEEEECCCCCCHHHCCCCCCEEEEEECCCCEEEEEHHHHHHHHCCHHHHHHHCHHHHHC
PQYSGPRCATHTQAFVDDIRGLFARSHAQGQRLGIESAPTGAIEALGQAGFELTDAATVV
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHH
EGAKSIKSVDELALIHRSVTLTEAAMTHMEAALRPGMSENELWSIFNQHVLATGGEYAET
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHEECCCCHHHH
RLLSSGARTNPWFQECSDKIIAPGELVAFDTDIVGCFGYYTDFSRTFHVPGAGAPNAEQK
HHHHCCCCCCCHHHHHCCCCCCCCCEEEECCHHHHHHHHHHCCCCEEECCCCCCCCHHHH
ALYRMAADQLERNIALLRPGMSFRDYSRQAWPIPDGYRENRYLDIVHGCGMTGEWPLIAH
HHHHHHHHHHHCCCEEECCCCCHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEE
DMDWDDVGYDGDIEPGMTLCVEAYIGHRDGTEGVKLEEQVLITEDGIDRLSTYGYSETLM
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCEECCEEEEECCCHHHHHHCCCCHHHC
AE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]