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The map label for this gene is atoB [H]

Identifier: 92115183

GI number: 92115183

Start: 3416659

End: 3417840

Strand: Direct

Name: atoB [H]

Synonym: Csal_3068

Alternate gene names: 92115183

Gene position: 3416659-3417840 (Clockwise)

Preceding gene: 92115182

Following gene: 92115184

Centisome position: 92.43

GC content: 67.68

Gene sequence:

>1182_bases
ATGCAAGACGTGGTGATCGTAGCGGCACGGCGCACCGCCATCGGCAGTTTCGGCGGCGCACTCGCCAGTCTCCCCGCGAC
CCAGCTCGGCGCTACGGTCATCGCGGACCTCCTTGCGCATACCGGTGTGGCCCCCGACCAGGTCGACGAGGTACTGCTCG
GCCAGGTACTCGCCGCCGGCTGCGGACAGAACCCCGCCCGCCAGGCGGCGATTCTCGGCGGCCTGCCCGCGGCGGTTCCC
GCCATGACCATCAACAAGGTCTGCGGCTCGGGACTCAAGGCCCTGCATCTTGCCACTCAGGCGATTCGCTGCGGTGATGC
CGAACTGATCATCGCCGGGGGCCAGGAGAACATGTCCGCCGCTCCGCATGTCCTGCCGCACTCGCGCACCGGGCAACGCA
TGGGCGACTGGACGGCAGTGGACACGATGATTCGCGATGGCCTCTGGGATGCCTTCAACGATATCCACATGGGGATCACC
GCCGAAAACCTCGCCGAGAAGTACACCATCACCCGGGAAGACATGGACGCCTTCGCCGCCGCGTCCCAGCAAAAGGCCAG
TGCCGCCATCGAGGCGGGGCGTTTCGCCGGTCAGATCGTGCCGGTGACGATACCCCAGCGCAAGGGCGATCCCGTGCATG
TCACCACCGACGAAGGGCCTCGGGCGGGCGTCACCGCCGAGCAACTCGCCGCACTGCGCCCGGCCTTCAAGCGTGATGGC
ACGGTCACCGCCGGCAATGCCTCGTCGCTCAACGACGGCGCGGCCGTGGCCATGCTGTGTTCGGCGGACAAGGCCAAGTC
ACTGGGGCTGGAGCCGCTCGCGGTGATCAAGGCCTATGCCAATGCCGGGGTCGATCCCAGCATCATGGGCATCGGCCCCG
CGCCGGCGACACGGCGCTGTCTGGAACGCGCCGGCTGGTCTCTCGATGAGCTGGACTTGATCGAGGCCAACGAAGCCTTC
GCCGCCCAGGCACTCGCCGTCAACAAGGAGCTCGGCTGGGACCCCGCCAAGATCAACGTCAACGGGGGTGCCATCGCCCT
GGGACACCCCATCGGCGCCTCCGGATGCCGGATACTGGTCACCCTGCTGCACGAGATGATCGCTCGTGATGCCAAGAAGG
GACTGGCCACGCTTTGCATCGGCGGCGGCCAGGGAGTGGCGCTGGCCATCGAACGGCCCTGA

Upstream 100 bases:

>100_bases
CTCGACTCGCCTACGCTATAAGACGTGATTCTTTGCGCGACGCTTCTGATACCGCACGGCGCGCATATCGGTATTTCTTC
TGCGGCGAAAGGAGTCTCTC

Downstream 100 bases:

>100_bases
GATGCCCGAGGCATTAATCAGAACGCCGTTTTGTAACGTCATGCAACAGCGCTGAACTTTCTTCCTTTCTCGCTTGCCTC
ATATCACGGCGCCCCGGTGG

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MQDVVIVAARRTAIGSFGGALASLPATQLGATVIADLLAHTGVAPDQVDEVLLGQVLAAGCGQNPARQAAILGGLPAAVP
AMTINKVCGSGLKALHLATQAIRCGDAELIIAGGQENMSAAPHVLPHSRTGQRMGDWTAVDTMIRDGLWDAFNDIHMGIT
AENLAEKYTITREDMDAFAAASQQKASAAIEAGRFAGQIVPVTIPQRKGDPVHVTTDEGPRAGVTAEQLAALRPAFKRDG
TVTAGNASSLNDGAAVAMLCSADKAKSLGLEPLAVIKAYANAGVDPSIMGIGPAPATRRCLERAGWSLDELDLIEANEAF
AAQALAVNKELGWDPAKINVNGGAIALGHPIGASGCRILVTLLHEMIARDAKKGLATLCIGGGQGVALAIERP

Sequences:

>Translated_393_residues
MQDVVIVAARRTAIGSFGGALASLPATQLGATVIADLLAHTGVAPDQVDEVLLGQVLAAGCGQNPARQAAILGGLPAAVP
AMTINKVCGSGLKALHLATQAIRCGDAELIIAGGQENMSAAPHVLPHSRTGQRMGDWTAVDTMIRDGLWDAFNDIHMGIT
AENLAEKYTITREDMDAFAAASQQKASAAIEAGRFAGQIVPVTIPQRKGDPVHVTTDEGPRAGVTAEQLAALRPAFKRDG
TVTAGNASSLNDGAAVAMLCSADKAKSLGLEPLAVIKAYANAGVDPSIMGIGPAPATRRCLERAGWSLDELDLIEANEAF
AAQALAVNKELGWDPAKINVNGGAIALGHPIGASGCRILVTLLHEMIARDAKKGLATLCIGGGQGVALAIERP
>Mature_393_residues
MQDVVIVAARRTAIGSFGGALASLPATQLGATVIADLLAHTGVAPDQVDEVLLGQVLAAGCGQNPARQAAILGGLPAAVP
AMTINKVCGSGLKALHLATQAIRCGDAELIIAGGQENMSAAPHVLPHSRTGQRMGDWTAVDTMIRDGLWDAFNDIHMGIT
AENLAEKYTITREDMDAFAAASQQKASAAIEAGRFAGQIVPVTIPQRKGDPVHVTTDEGPRAGVTAEQLAALRPAFKRDG
TVTAGNASSLNDGAAVAMLCSADKAKSLGLEPLAVIKAYANAGVDPSIMGIGPAPATRRCLERAGWSLDELDLIEANEAF
AAQALAVNKELGWDPAKINVNGGAIALGHPIGASGCRILVTLLHEMIARDAKKGLATLCIGGGQGVALAIERP

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI148539872, Length=391, Percent_Identity=53.1969309462916, Blast_Score=412, Evalue=1e-115,
Organism=Homo sapiens, GI167614485, Length=396, Percent_Identity=43.9393939393939, Blast_Score=320, Evalue=1e-87,
Organism=Homo sapiens, GI4557237, Length=393, Percent_Identity=43.5114503816794, Blast_Score=313, Evalue=1e-85,
Organism=Homo sapiens, GI4501853, Length=397, Percent_Identity=42.3173803526448, Blast_Score=273, Evalue=1e-73,
Organism=Homo sapiens, GI4504327, Length=428, Percent_Identity=31.3084112149533, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI194353979, Length=397, Percent_Identity=32.4937027707809, Blast_Score=156, Evalue=4e-38,
Organism=Escherichia coli, GI87082165, Length=392, Percent_Identity=65.8163265306122, Blast_Score=511, Evalue=1e-146,
Organism=Escherichia coli, GI1788554, Length=393, Percent_Identity=59.0330788804071, Blast_Score=420, Evalue=1e-119,
Organism=Escherichia coli, GI1787663, Length=401, Percent_Identity=45.8852867830424, Blast_Score=309, Evalue=2e-85,
Organism=Escherichia coli, GI48994986, Length=401, Percent_Identity=42.8927680798005, Blast_Score=257, Evalue=7e-70,
Organism=Escherichia coli, GI1788683, Length=409, Percent_Identity=32.2738386308068, Blast_Score=186, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI133906874, Length=390, Percent_Identity=46.4102564102564, Blast_Score=339, Evalue=2e-93,
Organism=Caenorhabditis elegans, GI25147385, Length=387, Percent_Identity=39.5348837209302, Blast_Score=276, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI17535921, Length=393, Percent_Identity=38.676844783715, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17551802, Length=428, Percent_Identity=31.3084112149533, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17535917, Length=393, Percent_Identity=31.8066157760814, Blast_Score=171, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6325229, Length=396, Percent_Identity=43.6868686868687, Blast_Score=305, Evalue=6e-84,
Organism=Saccharomyces cerevisiae, GI6322031, Length=395, Percent_Identity=37.9746835443038, Blast_Score=234, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24655093, Length=392, Percent_Identity=54.5918367346939, Blast_Score=420, Evalue=1e-117,
Organism=Drosophila melanogaster, GI24640423, Length=391, Percent_Identity=43.9897698209719, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI17648125, Length=392, Percent_Identity=42.3469387755102, Blast_Score=302, Evalue=2e-82,
Organism=Drosophila melanogaster, GI17137578, Length=431, Percent_Identity=31.554524361949, Blast_Score=173, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 40250; Mature: 40250

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDVVIVAARRTAIGSFGGALASLPATQLGATVIADLLAHTGVAPDQVDEVLLGQVLAAG
CCCEEEEEECHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
CGQNPARQAAILGGLPAAVPAMTINKVCGSGLKALHLATQAIRCGDAELIIAGGQENMSA
CCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCC
APHVLPHSRTGQRMGDWTAVDTMIRDGLWDAFNDIHMGITAENLAEKYTITREDMDAFAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHH
ASQQKASAAIEAGRFAGQIVPVTIPQRKGDPVHVTTDEGPRAGVTAEQLAALRPAFKRDG
HHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCC
TVTAGNASSLNDGAAVAMLCSADKAKSLGLEPLAVIKAYANAGVDPSIMGIGPAPATRRC
CEECCCCCCCCCCCEEEEEECCCHHHHCCCCHHHHHHHHHHCCCCCCEEECCCCHHHHHH
LERAGWSLDELDLIEANEAFAAQALAVNKELGWDPAKINVNGGAIALGHPIGASGCRILV
HHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCCHHHHHH
TLLHEMIARDAKKGLATLCIGGGQGVALAIERP
HHHHHHHHHHHHCCCEEEEEECCCCEEEEEECC
>Mature Secondary Structure
MQDVVIVAARRTAIGSFGGALASLPATQLGATVIADLLAHTGVAPDQVDEVLLGQVLAAG
CCCEEEEEECHHHHHHHCHHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
CGQNPARQAAILGGLPAAVPAMTINKVCGSGLKALHLATQAIRCGDAELIIAGGQENMSA
CCCCHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCC
APHVLPHSRTGQRMGDWTAVDTMIRDGLWDAFNDIHMGITAENLAEKYTITREDMDAFAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHH
ASQQKASAAIEAGRFAGQIVPVTIPQRKGDPVHVTTDEGPRAGVTAEQLAALRPAFKRDG
HHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCC
TVTAGNASSLNDGAAVAMLCSADKAKSLGLEPLAVIKAYANAGVDPSIMGIGPAPATRRC
CEECCCCCCCCCCCEEEEEECCCHHHHCCCCHHHHHHHHHHCCCCCCEEECCCCHHHHHH
LERAGWSLDELDLIEANEAFAAQALAVNKELGWDPAKINVNGGAIALGHPIGASGCRILV
HHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEECCCEEEECCCCCCCHHHHHH
TLLHEMIARDAKKGLATLCIGGGQGVALAIERP
HHHHHHHHHHHHCCCEEEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]