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The map label for this gene is zraR [H]

Identifier: 92115177

GI number: 92115177

Start: 3410072

End: 3411463

Strand: Direct

Name: zraR [H]

Synonym: Csal_3062

Alternate gene names: 92115177

Gene position: 3410072-3411463 (Clockwise)

Preceding gene: 92115176

Following gene: 92115178

Centisome position: 92.25

GC content: 66.95

Gene sequence:

>1392_bases
ATGAGCATCCACATGACGACGAGGCCCATGAGCAGGATTCTGATCGTTGAAAACGAAGACGCGACTCGCCACGCGTTGAA
GACGCTGCTCGAACGCCACGCCTACCGCGTCGAGGAAGCGGCATCGCTCGACGCCGCCCAGGCCCTGGCCCCCCAGACCT
TCGACCTGGTGATCTGCGACCTGCGTCTCGCGGGCGAGGACGGGACGCAGATGCTCGCCTTGAGCGCCCCCACCCCGGTG
CTGGTCATGACCGATCACGCCAGCTTGCGCAAGGCCGTGGTGGCGCTCAAGGAAGGCGCGGTCGATTGCATCACCAAGCC
GCTCGACGATGACGAGGTGGTGACGACCGTCGCACGGGTGTCGGGCAGCCCCGGGCCAGCGCGCGATGCCTCGCCGCCGG
GCGTGCCATCGGGAATGATCGGGGAATGCGCGGCCATGCAATGCGTCTATGAGCGCATTCGCAAGACCGCGCCCGCCGAT
GTCACCGTCCTGGTGCAGGGTGAGTCGGGGACCGGCAAGGAACTCGTCGCCCGAGCCCTGCACCGCCAGAGCCGGCGCGC
CAAGGCTCCCCTGATCTGCGTCAACTGTGCCGCGATTCCCGAGACCCTGATCGAGTCCGAGCTGTTCGGCCACGAAAAGG
GGGCCTTTACGGGCGCCAACAGTGCGCGCACCGGCCTGGTCGAGGCCGCCGACGGCGGCACCCTGTTCCTCGACGAGATC
GGCGAGTTGCCGCTGGATGCCCAGGCACGGCTGCTGCGGGTTCTGCAGGAAGGCGAGATCCGGCGCATTGGTTCGGTGGA
AACGCGTTATGTCGACGTGCGCCTGATTGCCGCCACCCACCGTGATCTGCAGTCGTTGTCACGCAGCGGCGAGTTCCGGC
TCGACCTGTACTACCGTCTCAATGTCATGCAGATCGACCTCCCGCCGCTGCGCGAACGCGATGACGACATCCTGGCCATC
GCCAAGATCCTGCTCGAGCGTGCCTGTGCACGCCATGCCCGCCCTGGCCTGCGCTTGTCGCGGGCCGCGCGCCGCGACAT
CCTCGGCTATGCATGGCCCGGCAACGTGCGTGAGCTCGAGAATGCCCTGGAGCGCGGCGTCATCCTCGCCGAAGGGCATC
TGATCCACCCCGACGACCTGGGGCTGCCCAGCGAGCGCGCATCTCGCGCCACGCCGCCCTCGGCCGAGCCCCCTCATTCT
TCCGATGACGAGGCGTCACTGGACGACGACCTGTCCCTGGAGGATTACTTCCAGCATTTCGTTCTCGAACACCAGGCACA
GATGAGCGAGACCGAGCTGGCCCAGAAGCTGGGCATCAGTCGCAAGTGCCTATGGGAGCGCCGCCAGCGCCTGGGCATCC
CGCGCAAGAAACAACCTCGCCGCATGGCGTGA

Upstream 100 bases:

>100_bases
GGGCCGGCGTCATGCCATGGTCGCAGGAGGCTCCGCTTGATCCGGCCAGCTGGCTCACGTCAGGATATTCGCGACTGCCG
CGCCGCCGGCCGCCGACTGC

Downstream 100 bases:

>100_bases
CGGCATCACACGCCCCCGCGACAAGCTCTCCCTCGCCGACTTTTTGTACCAGTCACGACTATGGTCTAAGCGCATCTCGC
CGTCTTTTTAGAGACCCTAG

Product: two-component response regulator CbrB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MSIHMTTRPMSRILIVENEDATRHALKTLLERHAYRVEEAASLDAAQALAPQTFDLVICDLRLAGEDGTQMLALSAPTPV
LVMTDHASLRKAVVALKEGAVDCITKPLDDDEVVTTVARVSGSPGPARDASPPGVPSGMIGECAAMQCVYERIRKTAPAD
VTVLVQGESGTGKELVARALHRQSRRAKAPLICVNCAAIPETLIESELFGHEKGAFTGANSARTGLVEAADGGTLFLDEI
GELPLDAQARLLRVLQEGEIRRIGSVETRYVDVRLIAATHRDLQSLSRSGEFRLDLYYRLNVMQIDLPPLRERDDDILAI
AKILLERACARHARPGLRLSRAARRDILGYAWPGNVRELENALERGVILAEGHLIHPDDLGLPSERASRATPPSAEPPHS
SDDEASLDDDLSLEDYFQHFVLEHQAQMSETELAQKLGISRKCLWERRQRLGIPRKKQPRRMA

Sequences:

>Translated_463_residues
MSIHMTTRPMSRILIVENEDATRHALKTLLERHAYRVEEAASLDAAQALAPQTFDLVICDLRLAGEDGTQMLALSAPTPV
LVMTDHASLRKAVVALKEGAVDCITKPLDDDEVVTTVARVSGSPGPARDASPPGVPSGMIGECAAMQCVYERIRKTAPAD
VTVLVQGESGTGKELVARALHRQSRRAKAPLICVNCAAIPETLIESELFGHEKGAFTGANSARTGLVEAADGGTLFLDEI
GELPLDAQARLLRVLQEGEIRRIGSVETRYVDVRLIAATHRDLQSLSRSGEFRLDLYYRLNVMQIDLPPLRERDDDILAI
AKILLERACARHARPGLRLSRAARRDILGYAWPGNVRELENALERGVILAEGHLIHPDDLGLPSERASRATPPSAEPPHS
SDDEASLDDDLSLEDYFQHFVLEHQAQMSETELAQKLGISRKCLWERRQRLGIPRKKQPRRMA
>Mature_462_residues
SIHMTTRPMSRILIVENEDATRHALKTLLERHAYRVEEAASLDAAQALAPQTFDLVICDLRLAGEDGTQMLALSAPTPVL
VMTDHASLRKAVVALKEGAVDCITKPLDDDEVVTTVARVSGSPGPARDASPPGVPSGMIGECAAMQCVYERIRKTAPADV
TVLVQGESGTGKELVARALHRQSRRAKAPLICVNCAAIPETLIESELFGHEKGAFTGANSARTGLVEAADGGTLFLDEIG
ELPLDAQARLLRVLQEGEIRRIGSVETRYVDVRLIAATHRDLQSLSRSGEFRLDLYYRLNVMQIDLPPLRERDDDILAIA
KILLERACARHARPGLRLSRAARRDILGYAWPGNVRELENALERGVILAEGHLIHPDDLGLPSERASRATPPSAEPPHSS
DDEASLDDDLSLEDYFQHFVLEHQAQMSETELAQKLGISRKCLWERRQRLGIPRKKQPRRMA

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=446, Percent_Identity=44.6188340807175, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI1788550, Length=465, Percent_Identity=40.4301075268817, Blast_Score=308, Evalue=6e-85,
Organism=Escherichia coli, GI1790299, Length=423, Percent_Identity=42.3167848699764, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI1788905, Length=377, Percent_Identity=41.6445623342175, Blast_Score=269, Evalue=3e-73,
Organism=Escherichia coli, GI1789087, Length=325, Percent_Identity=44.6153846153846, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI87082117, Length=323, Percent_Identity=44.8916408668731, Blast_Score=243, Evalue=1e-65,
Organism=Escherichia coli, GI87082152, Length=232, Percent_Identity=53.0172413793103, Blast_Score=236, Evalue=3e-63,
Organism=Escherichia coli, GI1789233, Length=321, Percent_Identity=41.7445482866044, Blast_Score=225, Evalue=4e-60,
Organism=Escherichia coli, GI1786524, Length=330, Percent_Identity=41.5151515151515, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI87081872, Length=231, Percent_Identity=46.3203463203463, Blast_Score=208, Evalue=8e-55,
Organism=Escherichia coli, GI1787583, Length=324, Percent_Identity=37.6543209876543, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1789828, Length=257, Percent_Identity=37.7431906614786, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI87081858, Length=314, Percent_Identity=30.5732484076433, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 50907; Mature: 50776

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIHMTTRPMSRILIVENEDATRHALKTLLERHAYRVEEAASLDAAQALAPQTFDLVICD
CEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
LRLAGEDGTQMLALSAPTPVLVMTDHASLRKAVVALKEGAVDCITKPLDDDEVVTTVARV
EEEECCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHH
SGSPGPARDASPPGVPSGMIGECAAMQCVYERIRKTAPADVTVLVQGESGTGKELVARAL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHH
HRQSRRAKAPLICVNCAAIPETLIESELFGHEKGAFTGANSARTGLVEAADGGTLFLDEI
HHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEEHHHH
GELPLDAQARLLRVLQEGEIRRIGSVETRYVDVRLIAATHRDLQSLSRSGEFRLDLYYRL
CCCCCCHHHHHHHHHHCCCCEECCCCEEEEEEEEEEEHHHHHHHHHHCCCCEEEEEEEEE
NVMQIDLPPLRERDDDILAIAKILLERACARHARPGLRLSRAARRDILGYAWPGNVRELE
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCEEECCCCCHHHHH
NALERGVILAEGHLIHPDDLGLPSERASRATPPSAEPPHSSDDEASLDDDLSLEDYFQHF
HHHHCCEEEECCCEECCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
VLEHQAQMSETELAQKLGISRKCLWERRQRLGIPRKKQPRRMA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SIHMTTRPMSRILIVENEDATRHALKTLLERHAYRVEEAASLDAAQALAPQTFDLVICD
EEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEE
LRLAGEDGTQMLALSAPTPVLVMTDHASLRKAVVALKEGAVDCITKPLDDDEVVTTVARV
EEEECCCCCEEEEEECCCCEEEEECCHHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHH
SGSPGPARDASPPGVPSGMIGECAAMQCVYERIRKTAPADVTVLVQGESGTGKELVARAL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHH
HRQSRRAKAPLICVNCAAIPETLIESELFGHEKGAFTGANSARTGLVEAADGGTLFLDEI
HHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCEEEHHHH
GELPLDAQARLLRVLQEGEIRRIGSVETRYVDVRLIAATHRDLQSLSRSGEFRLDLYYRL
CCCCCCHHHHHHHHHHCCCCEECCCCEEEEEEEEEEEHHHHHHHHHHCCCCEEEEEEEEE
NVMQIDLPPLRERDDDILAIAKILLERACARHARPGLRLSRAARRDILGYAWPGNVRELE
EEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCEEECCCCCHHHHH
NALERGVILAEGHLIHPDDLGLPSERASRATPPSAEPPHSSDDEASLDDDLSLEDYFQHF
HHHHCCEEEECCCEECCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
VLEHQAQMSETELAQKLGISRKCLWERRQRLGIPRKKQPRRMA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]