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The map label for this gene is truC [H]

Identifier: 92115011

GI number: 92115011

Start: 3226260

End: 3227045

Strand: Direct

Name: truC [H]

Synonym: Csal_2894

Alternate gene names: 92115011

Gene position: 3226260-3227045 (Clockwise)

Preceding gene: 92115003

Following gene: 92115012

Centisome position: 87.28

GC content: 69.21

Gene sequence:

>786_bases
ATGTCGTTGGAATTGCCCGTACTTTATCAGGACGAGCGCATGGTTGCCGTGCAAAAACCGTCGGGAATGCTCGTTCACCG
CAGTCCGATCGCCCGTGACGCGCGGGTGTTCGCCCTGCAGACCCTGCGCAACCAACTGGGGCGCCACGTCTATCCGGTCC
ACCGGCTCGACCGGCCGACCTCGGGGCTTCTGCTGTTCGCCCTCGACCCGGAGATGGCCCAGGCGCTGGGCGAGGAATTC
ACCGCGCACCGCGTGCACAAGCGCTACCTGGCGGTGGTCCGCGGCGTCGGCCCGGAGCAGGACCTGCTCGATTACGGCCT
GCGCGAGGAAGATGGCTCGCGGCCCAAGGCGGAAATGCCCGAACTCGAAGCCTGGACGGCCGTGCGCCGCCTGGACAGCG
TCGAACTGCCGGTGCGCATCGACCGTTATCCCCAGGTACGCTATTCCTTGATGGAGGCCCGGCCATGGACCGGGCGGCGG
CATCAGATTCGCCGCCACCTGGCGCGGCGTGGCTATCCGATCATCGGCGACGCCAAGCATGGCAAGGGCGCCCACAATCG
CTTCTTCCGCGAGCGACTGGACAGCCCGCGCCTGCTGCTCGCGGCCGTGGGCATGACGGTCTGGCACCCCGAGCAGGCAC
GCACGCTGCAGCTCGATGCGCCCCTGGCCGACGACATGCAGGCGCTGTTCGCGCGCTTCGGCTGGCAGGGCCACGCCCCG
GCGGCCCGCGTCGCCTGGCACGCAGAACGCCCCGCCGCGTTGTTGTCACCCGGCCACGACCGGTAA

Upstream 100 bases:

>100_bases
CCCCCAGCAGGCCCGTGACGACACCCAGGATCATCGGCTGTACATCCTATGTGGCAAGGTCGACAATAGGCGCCCTTCGA
GCTGGCCGAAGGTTCCCCTC

Downstream 100 bases:

>100_bases
CGAGGAACGATCACATGCAAGACGATTACGATTTCCGCTTCGGCGGCATCCGCCGACTGTACGGCGCCCAGGCCGCCGCG
TTCTTCCGCCGCGCCCACGT

Product: tRNA pseudouridine synthase C

Products: NA

Alternate protein names: tRNA pseudouridylate synthase C; tRNA-uridine isomerase C [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSLELPVLYQDERMVAVQKPSGMLVHRSPIARDARVFALQTLRNQLGRHVYPVHRLDRPTSGLLLFALDPEMAQALGEEF
TAHRVHKRYLAVVRGVGPEQDLLDYGLREEDGSRPKAEMPELEAWTAVRRLDSVELPVRIDRYPQVRYSLMEARPWTGRR
HQIRRHLARRGYPIIGDAKHGKGAHNRFFRERLDSPRLLLAAVGMTVWHPEQARTLQLDAPLADDMQALFARFGWQGHAP
AARVAWHAERPAALLSPGHDR

Sequences:

>Translated_261_residues
MSLELPVLYQDERMVAVQKPSGMLVHRSPIARDARVFALQTLRNQLGRHVYPVHRLDRPTSGLLLFALDPEMAQALGEEF
TAHRVHKRYLAVVRGVGPEQDLLDYGLREEDGSRPKAEMPELEAWTAVRRLDSVELPVRIDRYPQVRYSLMEARPWTGRR
HQIRRHLARRGYPIIGDAKHGKGAHNRFFRERLDSPRLLLAAVGMTVWHPEQARTLQLDAPLADDMQALFARFGWQGHAP
AARVAWHAERPAALLSPGHDR
>Mature_260_residues
SLELPVLYQDERMVAVQKPSGMLVHRSPIARDARVFALQTLRNQLGRHVYPVHRLDRPTSGLLLFALDPEMAQALGEEFT
AHRVHKRYLAVVRGVGPEQDLLDYGLREEDGSRPKAEMPELEAWTAVRRLDSVELPVRIDRYPQVRYSLMEARPWTGRRH
QIRRHLARRGYPIIGDAKHGKGAHNRFFRERLDSPRLLLAAVGMTVWHPEQARTLQLDAPLADDMQALFARFGWQGHAPA
ARVAWHAERPAALLSPGHDR

Specific function: Responsible for synthesis of pseudouridine from uracil- 65 in transfer RNAs [H]

COG id: COG0564

COG function: function code J; Pseudouridylate synthases, 23S RNA-specific

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pseudouridine synthase rluA family [H]

Homologues:

Organism=Homo sapiens, GI221316663, Length=193, Percent_Identity=29.0155440414508, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI221316667, Length=181, Percent_Identity=29.2817679558011, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1789155, Length=241, Percent_Identity=46.4730290456432, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1786244, Length=225, Percent_Identity=30.6666666666667, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787327, Length=236, Percent_Identity=28.3898305084746, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788946, Length=246, Percent_Identity=26.8292682926829, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320168, Length=177, Percent_Identity=32.7683615819209, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324506, Length=177, Percent_Identity=33.3333333333333, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6321608, Length=201, Percent_Identity=30.8457711442786, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006224
- InterPro:   IPR006145 [H]

Pfam domain/function: PF00849 PseudoU_synth_2 [H]

EC number: NA

Molecular weight: Translated: 29874; Mature: 29743

Theoretical pI: Translated: 10.50; Mature: 10.50

Prosite motif: PS01129 PSI_RLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLELPVLYQDERMVAVQKPSGMLVHRSPIARDARVFALQTLRNQLGRHVYPVHRLDRPT
CCCCCCEEECCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCC
SGLLLFALDPEMAQALGEEFTAHRVHKRYLAVVRGVGPEQDLLDYGLREEDGSRPKAEMP
CCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCC
ELEAWTAVRRLDSVELPVRIDRYPQVRYSLMEARPWTGRRHQIRRHLARRGYPIIGDAKH
CHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEECCCCC
GKGAHNRFFRERLDSPRLLLAAVGMTVWHPEQARTLQLDAPLADDMQALFARFGWQGHAP
CCCHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCC
AARVAWHAERPAALLSPGHDR
HHHHEECCCCCHHHCCCCCCC
>Mature Secondary Structure 
SLELPVLYQDERMVAVQKPSGMLVHRSPIARDARVFALQTLRNQLGRHVYPVHRLDRPT
CCCCCEEECCCEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCC
SGLLLFALDPEMAQALGEEFTAHRVHKRYLAVVRGVGPEQDLLDYGLREEDGSRPKAEMP
CCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCC
ELEAWTAVRRLDSVELPVRIDRYPQVRYSLMEARPWTGRRHQIRRHLARRGYPIIGDAKH
CHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEECCCCC
GKGAHNRFFRERLDSPRLLLAAVGMTVWHPEQARTLQLDAPLADDMQALFARFGWQGHAP
CCCHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCCCCCCC
AARVAWHAERPAALLSPGHDR
HHHHEECCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]