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The map label for this gene is pcbC [H]

Identifier: 92115002

GI number: 92115002

Start: 3216064

End: 3217077

Strand: Direct

Name: pcbC [H]

Synonym: Csal_2885

Alternate gene names: 92115002

Gene position: 3216064-3217077 (Clockwise)

Preceding gene: 92115001

Following gene: 92115003

Centisome position: 87.0

GC content: 67.65

Gene sequence:

>1014_bases
ATGACCCAGACATCGATCCCGCATATCGATCTCACGCCACTTCTCGAAGGCGCCGGCAGCGACGATCCCGCGCACGCCGA
TAGCGTCGCGGCCATCGTCGATGCCGCCTGCCGTTCCGGCTTCATGACCGTGGGCATCGCGCCGGGGCAACTGGCTCTGC
CCGACGACATCCATGCACGGCTGCTGCGCTTTTTCGAGCTCGATGCCGCCGCCAAGCAACGCCTGGCGCGGCACAAGTTC
GAACCGGCCAACGGCAATGTGTATCGCGGCTATTTTCCGCCGCAGAACGAGGACCCGACCTGGAAGGAAGGCATCGACCT
CGGCGCGGATGTCGCTCATCCCGAGCGCGCCGACGCGGCGAGCGGCGACCCGCTGCGCGAGCCCACGCCGCAGCCGCCGG
CAGCGTCCCTGCCGGGCTGGTCGGACGATGTCGCCGCCTATTACACGGCGATGGAATCCTTGGGCGGCGTGATCGCCGCA
GCGCTGGCCGAAGGCCTCGGCATGCCGCGCAACACGCTCATGCAGCCCTTCGAAAACGGCAATTCAACGCTACGCTTGAT
TCATTACCCGGAGCGTCCCGCCGAGACACTGGCCAGCATGCCGGCCGTCGATGGCCAGGGCGATGCCCGGCGCAGGATGG
TCGGCGTGCCGCATTGCGACAACGGCTTCATCACCCTGCTCTGGCAGGACCGCGTCGGCGGCCTGCAAGTGCAAACGCCC
GACGGCGACTGGGAAGACGTCGCACCGCGCGACAATGCCCTGGTGGTCAATTTCGGCCGCCTGCTGTCGGACTGGTCCGG
CGGGCGGATCCAGGCCACGGAACACCGCATCGTCGGCGGCACACGGTCGCGACACTCGATTCCGTTTTTCTTCGAGCCCG
CGGTCGAGGCCACCATCGAGGCCCCGAACGCCGATGGCGACGGCGGCTATGTCTACGGCGACCGGCTATGGCAGCGCATG
CAGGCCTTCGTCGAATTCCAGGGGCTGGAACGCGCCCCCGCTGCACGAGACTGA

Upstream 100 bases:

>100_bases
GCGACGATGGCCAGGTCGAATTGCTTTCCGACTATCCACTCGATACGCGGCTGCTGGCCGACTGAGGGCCAGTCGTCTCA
TCCCGACAGAAGCGAACGCC

Downstream 100 bases:

>100_bases
CACGGAATCGGCACCGCCGGACGTCCCTCGGCGACCGAACGATGCGACGACAACGTCGCCACCCTGACCGGGCCATGCTG
TATAGACGCTTGCTTTTCCC

Product: 2OG-Fe(II) oxygenase

Products: NA

Alternate protein names: IPNS [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTQTSIPHIDLTPLLEGAGSDDPAHADSVAAIVDAACRSGFMTVGIAPGQLALPDDIHARLLRFFELDAAAKQRLARHKF
EPANGNVYRGYFPPQNEDPTWKEGIDLGADVAHPERADAASGDPLREPTPQPPAASLPGWSDDVAAYYTAMESLGGVIAA
ALAEGLGMPRNTLMQPFENGNSTLRLIHYPERPAETLASMPAVDGQGDARRRMVGVPHCDNGFITLLWQDRVGGLQVQTP
DGDWEDVAPRDNALVVNFGRLLSDWSGGRIQATEHRIVGGTRSRHSIPFFFEPAVEATIEAPNADGDGGYVYGDRLWQRM
QAFVEFQGLERAPAARD

Sequences:

>Translated_337_residues
MTQTSIPHIDLTPLLEGAGSDDPAHADSVAAIVDAACRSGFMTVGIAPGQLALPDDIHARLLRFFELDAAAKQRLARHKF
EPANGNVYRGYFPPQNEDPTWKEGIDLGADVAHPERADAASGDPLREPTPQPPAASLPGWSDDVAAYYTAMESLGGVIAA
ALAEGLGMPRNTLMQPFENGNSTLRLIHYPERPAETLASMPAVDGQGDARRRMVGVPHCDNGFITLLWQDRVGGLQVQTP
DGDWEDVAPRDNALVVNFGRLLSDWSGGRIQATEHRIVGGTRSRHSIPFFFEPAVEATIEAPNADGDGGYVYGDRLWQRM
QAFVEFQGLERAPAARD
>Mature_336_residues
TQTSIPHIDLTPLLEGAGSDDPAHADSVAAIVDAACRSGFMTVGIAPGQLALPDDIHARLLRFFELDAAAKQRLARHKFE
PANGNVYRGYFPPQNEDPTWKEGIDLGADVAHPERADAASGDPLREPTPQPPAASLPGWSDDVAAYYTAMESLGGVIAAA
LAEGLGMPRNTLMQPFENGNSTLRLIHYPERPAETLASMPAVDGQGDARRRMVGVPHCDNGFITLLWQDRVGGLQVQTPD
GDWEDVAPRDNALVVNFGRLLSDWSGGRIQATEHRIVGGTRSRHSIPFFFEPAVEATIEAPNADGDGGYVYGDRLWQRMQ
AFVEFQGLERAPAARD

Specific function: Removes, in the presence of oxygen, 4 hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin [H]

COG id: COG3491

COG function: function code R; Isopenicillin N synthase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Fe2OG dioxygenase domain [H]

Homologues:

Organism=Drosophila melanogaster, GI24649039, Length=232, Percent_Identity=28.0172413793103, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI28572124, Length=185, Percent_Identity=31.8918918918919, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002057
- InterPro:   IPR002283
- InterPro:   IPR005123 [H]

Pfam domain/function: PF03171 2OG-FeII_Oxy [H]

EC number: =1.21.3.1 [H]

Molecular weight: Translated: 36456; Mature: 36325

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTSIPHIDLTPLLEGAGSDDPAHADSVAAIVDAACRSGFMTVGIAPGQLALPDDIHAR
CCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHH
LLRFFELDAAAKQRLARHKFEPANGNVYRGYFPPQNEDPTWKEGIDLGADVAHPERADAA
HHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCHHHCCCCCCCCCCCCCCCCC
SGDPLREPTPQPPAASLPGWSDDVAAYYTAMESLGGVIAAALAEGLGMPRNTLMQPFENG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
NSTLRLIHYPERPAETLASMPAVDGQGDARRRMVGVPHCDNGFITLLWQDRVGGLQVQTP
CCEEEEEECCCCHHHHHHHCCCCCCCCCHHHHEECCCCCCCCEEEEEEECCCCCEEEECC
DGDWEDVAPRDNALVVNFGRLLSDWSGGRIQATEHRIVGGTRSRHSIPFFFEPAVEATIE
CCCCCCCCCCCCEEEEEHHHHHCCCCCCEEEECCEEEECCCCCCCCCCEEECCCCCEEEE
APNADGDGGYVYGDRLWQRMQAFVEFQGLERAPAARD
CCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
TQTSIPHIDLTPLLEGAGSDDPAHADSVAAIVDAACRSGFMTVGIAPGQLALPDDIHAR
CCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHH
LLRFFELDAAAKQRLARHKFEPANGNVYRGYFPPQNEDPTWKEGIDLGADVAHPERADAA
HHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCHHHCCCCCCCCCCCCCCCCC
SGDPLREPTPQPPAASLPGWSDDVAAYYTAMESLGGVIAAALAEGLGMPRNTLMQPFENG
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
NSTLRLIHYPERPAETLASMPAVDGQGDARRRMVGVPHCDNGFITLLWQDRVGGLQVQTP
CCEEEEEECCCCHHHHHHHCCCCCCCCCHHHHEECCCCCCCCEEEEEEECCCCCEEEECC
DGDWEDVAPRDNALVVNFGRLLSDWSGGRIQATEHRIVGGTRSRHSIPFFFEPAVEATIE
CCCCCCCCCCCCEEEEEHHHHHCCCCCCEEEECCEEEECCCCCCCCCCEEECCCCCEEEE
APNADGDGGYVYGDRLWQRMQAFVEFQGLERAPAARD
CCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3130293 [H]