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The map label for this gene is 92114893

Identifier: 92114893

GI number: 92114893

Start: 3106568

End: 3107449

Strand: Direct

Name: 92114893

Synonym: Csal_2775

Alternate gene names: NA

Gene position: 3106568-3107449 (Clockwise)

Preceding gene: 92114890

Following gene: 92114894

Centisome position: 84.04

GC content: 61.9

Gene sequence:

>882_bases
ATGTTCGACGGATTTCGCGAATTCGATATCGAGGTGGAAAACGGACTCGTCATTCATGGCGTGATTGGCGGCGAAGGCCC
GCCATTGTTGCTGCTCCACGGCCACCCTCAGACCCACGTCATCTGGCATCGACTCGCCCCTCGTCTGGCCGAACGTTACA
CCGTGATCGCCACCGACTTGCGCGGCTACGGCGACTCCGGCAAGCCTGAGGGGGACAGCCGACACCTCAACTACAGCAAG
CGGCGCATGGCATTGGATCAGGTCGCCGTCATGCAGGCATTGGGGTACGAGCGTTTCTTTCTCTGCGGGCATGATCGTGG
CGGACGGGTCGCACACCGGCTGGCACTGGATCATGCCGAGCGAGTCGAAAGGCTGATGGTACTGGACATTGCGCCGACGC
TGGCGATGTACGAGGCCACCGATCTCGCATTCGCGACCGCCTACTGGCACTGGTTCTTTCTGATCCAGCCCAGACCGCTA
CCCGAATCCTGGATCGAAGCGGCACCCGCCGATTACGTCACCCGGATCATGGGAAGCCGTCATGCCGGGCTGGACCCGTT
CGATCCTCAAGCGATCGCCGAGTATCAACGCTGCCTGGCGCTCCCGGGCGCGGCTCACGGGCTGTGTGAAGACTATCGTG
CCTCTCGCACCATCGACCTGGAACACGACCGCTCGGACCGAGAGGCCGGCCGGCATCTATCCGTTCCACTGAAAGTACTC
TGGGGGGAATTCGGCACCATCGAACGTTGCTTCGATGCACTCGCCGAGTGGCGTGCCGTTTCCGGCGCTGGCGTCGAGGG
CGGCACGCTGCCCTGCGGACATTACCTCCCCGAAGAAGCACCGGATGCAATCCTTCATCAACTCATCGACTTCATGAGGT
AA

Upstream 100 bases:

>100_bases
CAACGCAATATTAAATCCAATAATACCCGGATTGTCCCGAAAACTTCAGCCTCTACACTAGGGACAAGCTGCTGGACAAG
CCAATGACGAGGCCAAACCA

Downstream 100 bases:

>100_bases
GCCCACCATGGCCAACGACCAGGCACCCCGCAAGGCTCACAGCATCGCCGTCATTCCCGGTGACGGCATCGGCACCGAAG
TCACGCCGGAAGGCGTTCGC

Product: alpha/beta hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MFDGFREFDIEVENGLVIHGVIGGEGPPLLLLHGHPQTHVIWHRLAPRLAERYTVIATDLRGYGDSGKPEGDSRHLNYSK
RRMALDQVAVMQALGYERFFLCGHDRGGRVAHRLALDHAERVERLMVLDIAPTLAMYEATDLAFATAYWHWFFLIQPRPL
PESWIEAAPADYVTRIMGSRHAGLDPFDPQAIAEYQRCLALPGAAHGLCEDYRASRTIDLEHDRSDREAGRHLSVPLKVL
WGEFGTIERCFDALAEWRAVSGAGVEGGTLPCGHYLPEEAPDAILHQLIDFMR

Sequences:

>Translated_293_residues
MFDGFREFDIEVENGLVIHGVIGGEGPPLLLLHGHPQTHVIWHRLAPRLAERYTVIATDLRGYGDSGKPEGDSRHLNYSK
RRMALDQVAVMQALGYERFFLCGHDRGGRVAHRLALDHAERVERLMVLDIAPTLAMYEATDLAFATAYWHWFFLIQPRPL
PESWIEAAPADYVTRIMGSRHAGLDPFDPQAIAEYQRCLALPGAAHGLCEDYRASRTIDLEHDRSDREAGRHLSVPLKVL
WGEFGTIERCFDALAEWRAVSGAGVEGGTLPCGHYLPEEAPDAILHQLIDFMR
>Mature_293_residues
MFDGFREFDIEVENGLVIHGVIGGEGPPLLLLHGHPQTHVIWHRLAPRLAERYTVIATDLRGYGDSGKPEGDSRHLNYSK
RRMALDQVAVMQALGYERFFLCGHDRGGRVAHRLALDHAERVERLMVLDIAPTLAMYEATDLAFATAYWHWFFLIQPRPL
PESWIEAAPADYVTRIMGSRHAGLDPFDPQAIAEYQRCLALPGAAHGLCEDYRASRTIDLEHDRSDREAGRHLSVPLKVL
WGEFGTIERCFDALAEWRAVSGAGVEGGTLPCGHYLPEEAPDAILHQLIDFMR

Specific function: Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has low activity towards chloroacetate [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=288, Percent_Identity=27.7777777777778, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI13376164, Length=288, Percent_Identity=27.7777777777778, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI218777837, Length=298, Percent_Identity=25.8389261744966, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17554012, Length=286, Percent_Identity=23.0769230769231, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17562298, Length=194, Percent_Identity=23.1958762886598, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.3 [H]

Molecular weight: Translated: 32941; Mature: 32941

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDGFREFDIEVENGLVIHGVIGGEGPPLLLLHGHPQTHVIWHRLAPRLAERYTVIATDL
CCCCCEEEEEEECCCEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHEEEEEEEC
RGYGDSGKPEGDSRHLNYSKRRMALDQVAVMQALGYERFFLCGHDRGGRVAHRLALDHAE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHH
RVERLMVLDIAPTLAMYEATDLAFATAYWHWFFLIQPRPLPESWIEAAPADYVTRIMGSR
HHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEEEEECCCCCCHHHHHCCCHHHHHHHHCCC
HAGLDPFDPQAIAEYQRCLALPGAAHGLCEDYRASRTIDLEHDRSDREAGRHLSVPLKVL
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEECCCCCCHHHCCCCCCCHHHHH
WGEFGTIERCFDALAEWRAVSGAGVEGGTLPCGHYLPEEAPDAILHQLIDFMR
HCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
>Mature Secondary Structure
MFDGFREFDIEVENGLVIHGVIGGEGPPLLLLHGHPQTHVIWHRLAPRLAERYTVIATDL
CCCCCEEEEEEECCCEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHHHHHHEEEEEEEC
RGYGDSGKPEGDSRHLNYSKRRMALDQVAVMQALGYERFFLCGHDRGGRVAHRLALDHAE
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHH
RVERLMVLDIAPTLAMYEATDLAFATAYWHWFFLIQPRPLPESWIEAAPADYVTRIMGSR
HHHHHHHHHHCCHHHHHHHHHHHHHHHEEEEEEEECCCCCCHHHHHCCCHHHHHHHHCCC
HAGLDPFDPQAIAEYQRCLALPGAAHGLCEDYRASRTIDLEHDRSDREAGRHLSVPLKVL
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEECCCCCCHHHCCCCCCCHHHHH
WGEFGTIERCFDALAEWRAVSGAGVEGGTLPCGHYLPEEAPDAILHQLIDFMR
HCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA