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The map label for this gene is lldP [C]

Identifier: 92114804

GI number: 92114804

Start: 3007964

End: 3009658

Strand: Direct

Name: lldP [C]

Synonym: Csal_2686

Alternate gene names: 92114804

Gene position: 3007964-3009658 (Clockwise)

Preceding gene: 92114801

Following gene: 161897779

Centisome position: 81.37

GC content: 64.84

Gene sequence:

>1695_bases
ATGAATCAAACGCTGCTCTCGCTACTCGCCTTCCTGCCATTGGTGCTGGCCGGCGTCTTGCTGATTGGCTTCCGGGTTCA
GGCCAAGGTCGCCATGCCCGTGGTGTTTCTGGTCACGGCATTGATCGCCCTGCTGGCCTGGGACATGACCTTCACACGGG
TGCTGGCTTCCACGTTCCAGGGGTTGATCCTCACCGTAGGCCTGCTGTGGATCATCTTCGGCGCCATCATGCTGCTCAAC
ACCCTGAAGCACTCCGGCGGGATCACCGCCATCCGCAACGGCTTCTCCAGCATCAGCCCCGACCGTCGCGTCCAGGCGCT
GATCGTGGCGTGGCTGTTCGGCTGCTTCATCGAAGGGGCGTCCGGCTTCGGCACGCCTGCCGCCGTCGCCGCGCCGTTGA
TGGTCGCACTGGGCTTCCCGGCATTGGGAGCCGTCACCGTGGGCATGATGATCCAGTCTACGCCGGTCTCCTTCGGCGCC
GTCGGCACGCCCATCGTGGTCGGCGTCACCGGCGGCCTCAATCGCAATGCGATCACCGAGCAACTGACCGCCAACGGCTC
GAGCTGGGAAAGCTTCTTTCGCCTGATCGCCTCGGAAGTCGCCATCACCCACGCCATCGTGGGCGTCCTGATGCCGTTGA
TCATGGTCATCGTGATGGTGCGCTTCTTCGGCGCCAACCGTTCCTGGAAGGAAGGCCTGTCGATCACACCGTTCGCGCTA
TTCACCGGCATCGCCTTCGTGGTTCCGTACGCGCTGGTGGGCGTCGTTCTGGGCCCCGAGTTCCCGTCGATGATCGGCGC
CCTGGTCGGGCTGGCCATCGTCGTGCCGGCCGCCAGGAAAGGCTTCCTGCTGCCCAAGGACACCTGGGATTTCCCCGACA
GCACGACCTGGCCGGACGAATGGCTGGGGAACCTGGAGATCAAGATGGACCAGGTCGCCGGCAAGGCGCCGATGTCGATA
TTCATGGGCTGGGTGCCCTACGTGCTGCTGGCCGTCCTGCTGGTCATCTCGCGCACCGTGCCGTCGGTCACTTCGGCACT
GCAATCGATCAGCGTGAGCTGGAACAACATCCTCGGCGAGAGCGGTGTGTCGGGTAGCCTTCAACCGCTGTATCTTCCCG
GCGGCATCATTCTCATCGTGGTGCTGCTCACCGTACTGCTGCACCGCATGCGCGCCAGCGAACTGGGGGCGGCCTTCAGC
GAGTCGACCAAGACGCTGCTGGGCGCCGGGTTCGTGTTGATCTTCACCGTGCCCATGGTGCGCATCCTGATCAACTCCGG
CGTCAACCAGGCGGACCTGGTCTCGATGCCGGTGGCCATGGCGCAACTGGTGGCCGATGGCGTGGGACACGTCTATCCGT
TCTTCTCGCCCGCCGTCGGGGCGCTGGGTGCCTTCATCGCCGGCTCCAACACGGTGTCCAACCTGATGCTCTCGGACTTC
CAGTTCAACGTCGCCGAGGCGCTGGGCGTGTCCACCGCGATGATGGTGGCCCTGCAGGCCGTGGGCGCCGCCGCCGGCAA
CATGATCGCCATTCACAACGTGGTTGCCGCCTCCGCCACCGTGGGGCTGCTGGGCCGCGAGGGCACCACCCTGCGCAAGA
CGATCCTCCCCACCCTGTACTACCTGATCTTCACGGGGACCATCGGGTTGGTCGCCTTCTACGTGATCGGCGTGAGCGAC
CCGCTCATGGGTTAG

Upstream 100 bases:

>100_bases
TGGCCTGACGGCATTTCACGTTTATCTTTCGCTCGACGACGCATGCCACGCGCTAGCCACTCGTCTCGCGCTGCACAACA
ACACAATCAGGGGCACTTCC

Downstream 100 bases:

>100_bases
CGCACGACCACTACGCGCTTTTACACAATCGCCACACTATCGCCCCGCCCCGGCCATGCCGGGCGGGGCTTTTCTTCGTG
GCTATTATTGGTAAGACCAA

Product: L-lactate transport

Products: Proton [Cytoplasm]; lactate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MNQTLLSLLAFLPLVLAGVLLIGFRVQAKVAMPVVFLVTALIALLAWDMTFTRVLASTFQGLILTVGLLWIIFGAIMLLN
TLKHSGGITAIRNGFSSISPDRRVQALIVAWLFGCFIEGASGFGTPAAVAAPLMVALGFPALGAVTVGMMIQSTPVSFGA
VGTPIVVGVTGGLNRNAITEQLTANGSSWESFFRLIASEVAITHAIVGVLMPLIMVIVMVRFFGANRSWKEGLSITPFAL
FTGIAFVVPYALVGVVLGPEFPSMIGALVGLAIVVPAARKGFLLPKDTWDFPDSTTWPDEWLGNLEIKMDQVAGKAPMSI
FMGWVPYVLLAVLLVISRTVPSVTSALQSISVSWNNILGESGVSGSLQPLYLPGGIILIVVLLTVLLHRMRASELGAAFS
ESTKTLLGAGFVLIFTVPMVRILINSGVNQADLVSMPVAMAQLVADGVGHVYPFFSPAVGALGAFIAGSNTVSNLMLSDF
QFNVAEALGVSTAMMVALQAVGAAAGNMIAIHNVVAASATVGLLGREGTTLRKTILPTLYYLIFTGTIGLVAFYVIGVSD
PLMG

Sequences:

>Translated_564_residues
MNQTLLSLLAFLPLVLAGVLLIGFRVQAKVAMPVVFLVTALIALLAWDMTFTRVLASTFQGLILTVGLLWIIFGAIMLLN
TLKHSGGITAIRNGFSSISPDRRVQALIVAWLFGCFIEGASGFGTPAAVAAPLMVALGFPALGAVTVGMMIQSTPVSFGA
VGTPIVVGVTGGLNRNAITEQLTANGSSWESFFRLIASEVAITHAIVGVLMPLIMVIVMVRFFGANRSWKEGLSITPFAL
FTGIAFVVPYALVGVVLGPEFPSMIGALVGLAIVVPAARKGFLLPKDTWDFPDSTTWPDEWLGNLEIKMDQVAGKAPMSI
FMGWVPYVLLAVLLVISRTVPSVTSALQSISVSWNNILGESGVSGSLQPLYLPGGIILIVVLLTVLLHRMRASELGAAFS
ESTKTLLGAGFVLIFTVPMVRILINSGVNQADLVSMPVAMAQLVADGVGHVYPFFSPAVGALGAFIAGSNTVSNLMLSDF
QFNVAEALGVSTAMMVALQAVGAAAGNMIAIHNVVAASATVGLLGREGTTLRKTILPTLYYLIFTGTIGLVAFYVIGVSD
PLMG
>Mature_564_residues
MNQTLLSLLAFLPLVLAGVLLIGFRVQAKVAMPVVFLVTALIALLAWDMTFTRVLASTFQGLILTVGLLWIIFGAIMLLN
TLKHSGGITAIRNGFSSISPDRRVQALIVAWLFGCFIEGASGFGTPAAVAAPLMVALGFPALGAVTVGMMIQSTPVSFGA
VGTPIVVGVTGGLNRNAITEQLTANGSSWESFFRLIASEVAITHAIVGVLMPLIMVIVMVRFFGANRSWKEGLSITPFAL
FTGIAFVVPYALVGVVLGPEFPSMIGALVGLAIVVPAARKGFLLPKDTWDFPDSTTWPDEWLGNLEIKMDQVAGKAPMSI
FMGWVPYVLLAVLLVISRTVPSVTSALQSISVSWNNILGESGVSGSLQPLYLPGGIILIVVLLTVLLHRMRASELGAAFS
ESTKTLLGAGFVLIFTVPMVRILINSGVNQADLVSMPVAMAQLVADGVGHVYPFFSPAVGALGAFIAGSNTVSNLMLSDF
QFNVAEALGVSTAMMVALQAVGAAAGNMIAIHNVVAASATVGLLGREGTTLRKTILPTLYYLIFTGTIGLVAFYVIGVSD
PLMG

Specific function: May play a role in L-lactate transport [H]

COG id: COG1620

COG function: function code C; L-lactate permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lactate permease family [H]

Homologues:

Organism=Escherichia coli, GI1790031, Length=594, Percent_Identity=26.5993265993266, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1789347, Length=347, Percent_Identity=28.2420749279539, Blast_Score=105, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003804 [H]

Pfam domain/function: PF02652 Lactate_perm [H]

EC number: NA

Molecular weight: Translated: 59142; Mature: 59142

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQTLLSLLAFLPLVLAGVLLIGFRVQAKVAMPVVFLVTALIALLAWDMTFTRVLASTFQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLILTVGLLWIIFGAIMLLNTLKHSGGITAIRNGFSSISPDRRVQALIVAWLFGCFIEGA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHCCCCHHHHHHHHHHHHHHHHHHCC
SGFGTPAAVAAPLMVALGFPALGAVTVGMMIQSTPVSFGAVGTPIVVGVTGGLNRNAITE
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHH
QLTANGSSWESFFRLIASEVAITHAIVGVLMPLIMVIVMVRFFGANRSWKEGLSITPFAL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHH
FTGIAFVVPYALVGVVLGPEFPSMIGALVGLAIVVPAARKGFLLPKDTWDFPDSTTWPDE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHH
WLGNLEIKMDQVAGKAPMSIFMGWVPYVLLAVLLVISRTVPSVTSALQSISVSWNNILGE
HCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
SGVSGSLQPLYLPGGIILIVVLLTVLLHRMRASELGAAFSESTKTLLGAGFVLIFTVPMV
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILINSGVNQADLVSMPVAMAQLVADGVGHVYPFFSPAVGALGAFIAGSNTVSNLMLSDF
HHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
QFNVAEALGVSTAMMVALQAVGAAAGNMIAIHNVVAASATVGLLGREGTTLRKTILPTLY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
YLIFTGTIGLVAFYVIGVSDPLMG
HHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNQTLLSLLAFLPLVLAGVLLIGFRVQAKVAMPVVFLVTALIALLAWDMTFTRVLASTFQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLILTVGLLWIIFGAIMLLNTLKHSGGITAIRNGFSSISPDRRVQALIVAWLFGCFIEGA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCHHCCCCHHHHHHHHHHHHHHHHHHCC
SGFGTPAAVAAPLMVALGFPALGAVTVGMMIQSTPVSFGAVGTPIVVGVTGGLNRNAITE
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCHHHHH
QLTANGSSWESFFRLIASEVAITHAIVGVLMPLIMVIVMVRFFGANRSWKEGLSITPFAL
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCHHHH
FTGIAFVVPYALVGVVLGPEFPSMIGALVGLAIVVPAARKGFLLPKDTWDFPDSTTWPDE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHH
WLGNLEIKMDQVAGKAPMSIFMGWVPYVLLAVLLVISRTVPSVTSALQSISVSWNNILGE
HCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
SGVSGSLQPLYLPGGIILIVVLLTVLLHRMRASELGAAFSESTKTLLGAGFVLIFTVPMV
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RILINSGVNQADLVSMPVAMAQLVADGVGHVYPFFSPAVGALGAFIAGSNTVSNLMLSDF
HHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHH
QFNVAEALGVSTAMMVALQAVGAAAGNMIAIHNVVAASATVGLLGREGTTLRKTILPTLY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
YLIFTGTIGLVAFYVIGVSDPLMG
HHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; lactate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + lactate [Periplasm] = Proton [Cytoplasm] + lactate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]