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The map label for this gene is aaeB [H]

Identifier: 92114800

GI number: 92114800

Start: 3003534

End: 3005609

Strand: Direct

Name: aaeB [H]

Synonym: Csal_2682

Alternate gene names: 92114800

Gene position: 3003534-3005609 (Clockwise)

Preceding gene: 92114799

Following gene: 92114801

Centisome position: 81.25

GC content: 67.34

Gene sequence:

>2076_bases
ATGTCGTCGACGACACGGACGCAGACTGAGCCGCCCATGTCGCCCTGGATCGAGACCTACCTGACGCCCTCGAAGACATC
GCTGCAGTTCGCCGCCAAGACCACCCTGGCGATGCTGCTGGCGCTGTACATCGCCTTGTGGTGCGATCTCGACCGCCCCT
ACTGGGCGCTGATCTCGGCGGCGTTCCTGCAGATCCGGCCGATGAGCGGCATGGTGGTCGAAAAGGGCATCTGCCAGATC
GGCGGCACCCTCATCGGCGCGCTGGCCGGCATCGTCATCATGGCCTTCTTCGCCCAGGCCCGCGTGCCCGCGCTGATCGC
GCTGACCCTGTGGATCATGCTCTGCGCCTATGGCAGTTCGCTGCTGCGCAACAACTTCTCCTACGGCTGCATCATGGGCG
CCGTGACCGCGATGCTGATCGTGGTGATTTCCGCCAACCAGCCCCCGAGCGGCATCTTCGACATCGCCGTGGCGCGGCTC
TCCGAACTCGGTCTCGGGGCGCTCTGCGCCACCCTGGTCAGCGCCCTGCTGTGGCCCACGCACGTCAAGGAGCATCTCGC
CGGGCAGGCCGACGAGGTCATCAACCAGGCCTTCACGCATGCCGGACAGCGGCTGGACGCCAGCGATGACGCTGCCGCCA
TGCAGCAGTCGCTGACCGCCAGCCTCGAGCCGCTGACCATGCTCGAGACCGATAGCCAGGCGGCGCGCTACGAAGGCCCC
GACGGCAACGGGCGCATCCGCGCCACCCACGTGCTGACGCGGCGTACCCTACGTTTCTTCGCCACGCTGGGGGCGCTGCA
TCAGCTACTCCACGATCATCGCGATCGCATCAACGCGCCCCTGCAGCAGCTCGCCACCGAAATCGCCGAAGGCTTTCGCG
GCGCCGAGCACGTCAAGGGCGTCCCCGCGGCCCGCCGTGAACTGCAGGCGCTGCGCAAGCGCGCCCATGGCTACTCCGAC
ACGCAGCTCGATCCGCTGCAGCGGCGCGTCATCCTGGCGCTCCGTGAGGTGCTCGGCCACGCCATGATCATGCTCGACGC
CCGCGAGGCCATCGCCCACCCGGGGCGTAAACAGCTACGCGCCGGCTCCCTGTCCTGGCATCGCGATCATCTGGTGGCGC
TGCTCAACGCCGGCCGCGCGGGGCTGGTCTTCTCGTGCCTGGCGGTGTTCTGGCTGCAGACCCACTGGAGCAACGGCCAG
GTGGCCATGCTGCTCGGCACCCTGTTCTCGGCCTTCTTCGCCACGCGCGACAACCCCGTGACGATCTGCATGATGTTCTT
CAAGGGCATGCTGGCGGCGTTGCCCAGTGCCTTCCTGTTCGGGCATGTCCTGCTGTCGCAGGCCAACGGCTTTCCCATGC
TTGCCATGCTGTTCGTCACGCCCCTGTTCCTGGGGCTGCTCGGCGCCTCCAATCCTCGATTGATGGGTTACTGCCTGGCC
TTCACCATCTTCAATATCCTGCTGACCATGCCGGGCAACGGCATGGACTTTTCCTTCGACAGCTTCGCCAACCGCGCCAT
CGCCGTGATCGTCGGGTTGAGCGCCGTGGTGATGGGCTTCCGCCTGATTCCGGGTCTCGGGGCACCGATCCGGCGCCGCC
GCCTGATCGGCGCCATCAGCCATGACCTGCGCCACATCGGCGACTTGCCCCTGCACGAGGAAGAAAGCCGTTTCAGCGGG
CGCATGGCCGATCGCCTGCTGCAATTGGCGCGCCATGACGACATGCTGCCCGAGGATCACCGCCATTTGTTCATGATCGG
CCTCAACGGGCTCGATCTGGGACGTTCCTGCCTGCGCCTGCGCCATCGCCTGGACGATGCCGCGCCGCCCGTGCGTGACG
CCATGCGGCACTTGCTGACCACCCTCGCCGCCGCGTTCGAGGACAGCGCCCACGGCCGCGCGCCACAGGGCATCCAGGCG
GCCGGACGAGCGCTGGATGACGCGCTCGTCCGCCATGGCGATATCGAGGAGGATTGGCGGTGGCTACTGGCAGGGCTGGT
CGAGCGGCTCGAGCTCACCCTGGCGCGTCAGGCCAATGTCATGGCCGAGCGACTGACACCGGCACCCGCCGCCTGA

Upstream 100 bases:

>100_bases
TTCAACTGGGTACGGCTGGCACAACGCATCCCGGTGCGCATCGAACTCGACGACGTTCCCGAGGGGACGCTGCTGAGTGC
CGGAATGACGGCCACGATCC

Downstream 100 bases:

>100_bases
TGACGACGATGAGAGACCCGAGGAGCACCATGCAGATTCGAGCTTTCCGCGATACCGACGAAGCGGCCATCATTGCGCTC
TGGGAACGCTGCGGCCTGAC

Product: fusaric acid resistance protein

Products: NA

Alternate protein names: pHBA efflux pump protein B [H]

Number of amino acids: Translated: 691; Mature: 690

Protein sequence:

>691_residues
MSSTTRTQTEPPMSPWIETYLTPSKTSLQFAAKTTLAMLLALYIALWCDLDRPYWALISAAFLQIRPMSGMVVEKGICQI
GGTLIGALAGIVIMAFFAQARVPALIALTLWIMLCAYGSSLLRNNFSYGCIMGAVTAMLIVVISANQPPSGIFDIAVARL
SELGLGALCATLVSALLWPTHVKEHLAGQADEVINQAFTHAGQRLDASDDAAAMQQSLTASLEPLTMLETDSQAARYEGP
DGNGRIRATHVLTRRTLRFFATLGALHQLLHDHRDRINAPLQQLATEIAEGFRGAEHVKGVPAARRELQALRKRAHGYSD
TQLDPLQRRVILALREVLGHAMIMLDAREAIAHPGRKQLRAGSLSWHRDHLVALLNAGRAGLVFSCLAVFWLQTHWSNGQ
VAMLLGTLFSAFFATRDNPVTICMMFFKGMLAALPSAFLFGHVLLSQANGFPMLAMLFVTPLFLGLLGASNPRLMGYCLA
FTIFNILLTMPGNGMDFSFDSFANRAIAVIVGLSAVVMGFRLIPGLGAPIRRRRLIGAISHDLRHIGDLPLHEEESRFSG
RMADRLLQLARHDDMLPEDHRHLFMIGLNGLDLGRSCLRLRHRLDDAAPPVRDAMRHLLTTLAAAFEDSAHGRAPQGIQA
AGRALDDALVRHGDIEEDWRWLLAGLVERLELTLARQANVMAERLTPAPAA

Sequences:

>Translated_691_residues
MSSTTRTQTEPPMSPWIETYLTPSKTSLQFAAKTTLAMLLALYIALWCDLDRPYWALISAAFLQIRPMSGMVVEKGICQI
GGTLIGALAGIVIMAFFAQARVPALIALTLWIMLCAYGSSLLRNNFSYGCIMGAVTAMLIVVISANQPPSGIFDIAVARL
SELGLGALCATLVSALLWPTHVKEHLAGQADEVINQAFTHAGQRLDASDDAAAMQQSLTASLEPLTMLETDSQAARYEGP
DGNGRIRATHVLTRRTLRFFATLGALHQLLHDHRDRINAPLQQLATEIAEGFRGAEHVKGVPAARRELQALRKRAHGYSD
TQLDPLQRRVILALREVLGHAMIMLDAREAIAHPGRKQLRAGSLSWHRDHLVALLNAGRAGLVFSCLAVFWLQTHWSNGQ
VAMLLGTLFSAFFATRDNPVTICMMFFKGMLAALPSAFLFGHVLLSQANGFPMLAMLFVTPLFLGLLGASNPRLMGYCLA
FTIFNILLTMPGNGMDFSFDSFANRAIAVIVGLSAVVMGFRLIPGLGAPIRRRRLIGAISHDLRHIGDLPLHEEESRFSG
RMADRLLQLARHDDMLPEDHRHLFMIGLNGLDLGRSCLRLRHRLDDAAPPVRDAMRHLLTTLAAAFEDSAHGRAPQGIQA
AGRALDDALVRHGDIEEDWRWLLAGLVERLELTLARQANVMAERLTPAPAA
>Mature_690_residues
SSTTRTQTEPPMSPWIETYLTPSKTSLQFAAKTTLAMLLALYIALWCDLDRPYWALISAAFLQIRPMSGMVVEKGICQIG
GTLIGALAGIVIMAFFAQARVPALIALTLWIMLCAYGSSLLRNNFSYGCIMGAVTAMLIVVISANQPPSGIFDIAVARLS
ELGLGALCATLVSALLWPTHVKEHLAGQADEVINQAFTHAGQRLDASDDAAAMQQSLTASLEPLTMLETDSQAARYEGPD
GNGRIRATHVLTRRTLRFFATLGALHQLLHDHRDRINAPLQQLATEIAEGFRGAEHVKGVPAARRELQALRKRAHGYSDT
QLDPLQRRVILALREVLGHAMIMLDAREAIAHPGRKQLRAGSLSWHRDHLVALLNAGRAGLVFSCLAVFWLQTHWSNGQV
AMLLGTLFSAFFATRDNPVTICMMFFKGMLAALPSAFLFGHVLLSQANGFPMLAMLFVTPLFLGLLGASNPRLMGYCLAF
TIFNILLTMPGNGMDFSFDSFANRAIAVIVGLSAVVMGFRLIPGLGAPIRRRRLIGAISHDLRHIGDLPLHEEESRFSGR
MADRLLQLARHDDMLPEDHRHLFMIGLNGLDLGRSCLRLRHRLDDAAPPVRDAMRHLLTTLAAAFEDSAHGRAPQGIQAA
GRALDDALVRHGDIEEDWRWLLAGLVERLELTLARQANVMAERLTPAPAA

Specific function: Efflux pump whose substrates are p-hydroxybenzoic acid (pHBA), 6-hydroxy-2-naphthoic and 2-hydroxycinnamate. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell [H]

COG id: COG1289

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family [H]

Homologues:

Organism=Escherichia coli, GI1789636, Length=620, Percent_Identity=25.6451612903226, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787933, Length=677, Percent_Identity=22.7474150664697, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006726 [H]

Pfam domain/function: PF04632 FUSC [H]

EC number: NA

Molecular weight: Translated: 75667; Mature: 75536

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSTTRTQTEPPMSPWIETYLTPSKTSLQFAAKTTLAMLLALYIALWCDLDRPYWALISA
CCCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AFLQIRPMSGMVVEKGICQIGGTLIGALAGIVIMAFFAQARVPALIALTLWIMLCAYGSS
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHH
LLRNNFSYGCIMGAVTAMLIVVISANQPPSGIFDIAVARLSELGLGALCATLVSALLWPT
HHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
HVKEHLAGQADEVINQAFTHAGQRLDASDDAAAMQQSLTASLEPLTMLETDSQAARYEGP
HHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHCCCCC
DGNGRIRATHVLTRRTLRFFATLGALHQLLHDHRDRINAPLQQLATEIAEGFRGAEHVKG
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHCC
VPAARRELQALRKRAHGYSDTQLDPLQRRVILALREVLGHAMIMLDAREAIAHPGRKQLR
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHH
AGSLSWHRDHLVALLNAGRAGLVFSCLAVFWLQTHWSNGQVAMLLGTLFSAFFATRDNPV
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCH
TICMMFFKGMLAALPSAFLFGHVLLSQANGFPMLAMLFVTPLFLGLLGASNPRLMGYCLA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
FTIFNILLTMPGNGMDFSFDSFANRAIAVIVGLSAVVMGFRLIPGLGAPIRRRRLIGAIS
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
HDLRHIGDLPLHEEESRFSGRMADRLLQLARHDDMLPEDHRHLFMIGLNGLDLGRSCLRL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHH
RHRLDDAAPPVRDAMRHLLTTLAAAFEDSAHGRAPQGIQAAGRALDDALVRHGDIEEDWR
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
WLLAGLVERLELTLARQANVMAERLTPAPAA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SSTTRTQTEPPMSPWIETYLTPSKTSLQFAAKTTLAMLLALYIALWCDLDRPYWALISA
CCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AFLQIRPMSGMVVEKGICQIGGTLIGALAGIVIMAFFAQARVPALIALTLWIMLCAYGSS
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHH
LLRNNFSYGCIMGAVTAMLIVVISANQPPSGIFDIAVARLSELGLGALCATLVSALLWPT
HHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
HVKEHLAGQADEVINQAFTHAGQRLDASDDAAAMQQSLTASLEPLTMLETDSQAARYEGP
HHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHCCCCC
DGNGRIRATHVLTRRTLRFFATLGALHQLLHDHRDRINAPLQQLATEIAEGFRGAEHVKG
CCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHCC
VPAARRELQALRKRAHGYSDTQLDPLQRRVILALREVLGHAMIMLDAREAIAHPGRKQLR
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHH
AGSLSWHRDHLVALLNAGRAGLVFSCLAVFWLQTHWSNGQVAMLLGTLFSAFFATRDNPV
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCH
TICMMFFKGMLAALPSAFLFGHVLLSQANGFPMLAMLFVTPLFLGLLGASNPRLMGYCLA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
FTIFNILLTMPGNGMDFSFDSFANRAIAVIVGLSAVVMGFRLIPGLGAPIRRRRLIGAIS
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
HDLRHIGDLPLHEEESRFSGRMADRLLQLARHDDMLPEDHRHLFMIGLNGLDLGRSCLRL
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHH
RHRLDDAAPPVRDAMRHLLTTLAAAFEDSAHGRAPQGIQAAGRALDDALVRHGDIEEDWR
HHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHH
WLLAGLVERLELTLARQANVMAERLTPAPAA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA