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The map label for this gene is hmuV [H]

Identifier: 92114667

GI number: 92114667

Start: 2860352

End: 2861143

Strand: Direct

Name: hmuV [H]

Synonym: Csal_2549

Alternate gene names: 92114667

Gene position: 2860352-2861143 (Clockwise)

Preceding gene: 92114666

Following gene: 92114676

Centisome position: 77.38

GC content: 71.21

Gene sequence:

>792_bases
ATGCTGTCGCTCTTCAATACGGCTCTCGAGGGCACCCCAAGCCTGAGGCCGTTCAGCGATCGCCTGGTGCCCGGCGAGCT
GCTCGGTATCTGCGGGCCGCACGGCGCCGGCAAGAGCACCCTGATCGGCCTGCTCGCCGGCCTCTATCGACCCACGCGGG
GCAGCATCTGCCTCGATGGCCAGCCGCTGCACTGCTGGCCCAGCGCCTATCGCGCCCAGCGCATCGCGCATGTCATCGCC
CCTCCGCGAAGTCTTGCCGACTGGCGTGTGCGCGACCTGGTGGGACTCGGGCTGCTGGAGAGCTGCTCGCGCGTCGTGCA
GCAAGGCGCCGCTTCGCCCCCCTGCCTGCCGGTGGCGGTGGAGACGGCGCTCGCGGCACTCGACCTGCAGGGCGTGAGCG
ACCGACGCCTGGGTACGCTCGACGCCGTCAACGCCCAGCGAGCCATGATCGCGCGGGCACTGTGCCAGGTCGCGGCGGCG
CCCTACTGCCCCTGCCGGCAGCGCCGCGACAACGGCATCCTGCTGCTCGACCTGGAACCTCTGGCACACGATCAGGAACA
GCGCCTGCTGGCCGATCTGGGCGCCGCCTCACGGCGCCACCGGCTCTGCATCGTACCGGTGGTCAGCCCCTGCGATGCCA
GCCTTGCGCATTGCGATCGCGTCTGGTGGATGGATGGCGGGTCGCGCCGTGCCGACCTGTCGCCGTCGGTCCGCCACGTC
CTGCGCGTGCAGGTCTCCTCGGCCGAGCGTACCCGGCCGAACGCACCACACCCCAATGACGCGGCGCCATGA

Upstream 100 bases:

>100_bases
TCGACGGGCCGTTCTGGTGGCACGCAAGCCGGAGTGACTTGCCCTTCTTCGTCATGCGAACGATAATATTTATCATTATC
ATCGTCGAAGGAGACTCCTC

Downstream 100 bases:

>100_bases
CTCGCCCCCGACGACTCAGTGAGTCTCGGTGTGTTCGGCCTGCAAGGCCTCGCGTCGAATGCGCCAGTCTTCCAGCGCCA
TGCGTGCGCGCGCATGCCGC

Product: ABC transporter-like protein

Products: ADP; phosphate; iron (III) hydroxamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MLSLFNTALEGTPSLRPFSDRLVPGELLGICGPHGAGKSTLIGLLAGLYRPTRGSICLDGQPLHCWPSAYRAQRIAHVIA
PPRSLADWRVRDLVGLGLLESCSRVVQQGAASPPCLPVAVETALAALDLQGVSDRRLGTLDAVNAQRAMIARALCQVAAA
PYCPCRQRRDNGILLLDLEPLAHDQEQRLLADLGAASRRHRLCIVPVVSPCDASLAHCDRVWWMDGGSRRADLSPSVRHV
LRVQVSSAERTRPNAPHPNDAAP

Sequences:

>Translated_263_residues
MLSLFNTALEGTPSLRPFSDRLVPGELLGICGPHGAGKSTLIGLLAGLYRPTRGSICLDGQPLHCWPSAYRAQRIAHVIA
PPRSLADWRVRDLVGLGLLESCSRVVQQGAASPPCLPVAVETALAALDLQGVSDRRLGTLDAVNAQRAMIARALCQVAAA
PYCPCRQRRDNGILLLDLEPLAHDQEQRLLADLGAASRRHRLCIVPVVSPCDASLAHCDRVWWMDGGSRRADLSPSVRHV
LRVQVSSAERTRPNAPHPNDAAP
>Mature_263_residues
MLSLFNTALEGTPSLRPFSDRLVPGELLGICGPHGAGKSTLIGLLAGLYRPTRGSICLDGQPLHCWPSAYRAQRIAHVIA
PPRSLADWRVRDLVGLGLLESCSRVVQQGAASPPCLPVAVETALAALDLQGVSDRRLGTLDAVNAQRAMIARALCQVAAA
PYCPCRQRRDNGILLLDLEPLAHDQEQRLLADLGAASRRHRLCIVPVVSPCDASLAHCDRVWWMDGGSRRADLSPSVRHV
LRVQVSSAERTRPNAPHPNDAAP

Specific function: Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system [H]

COG id: COG1120

COG function: function code PH; ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1786345, Length=263, Percent_Identity=28.5171102661597, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR015863
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 28303; Mature: 28303

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLFNTALEGTPSLRPFSDRLVPGELLGICGPHGAGKSTLIGLLAGLYRPTRGSICLDG
CCCHHHHHHCCCCCCCCCHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEECC
QPLHCWPSAYRAQRIAHVIAPPRSLADWRVRDLVGLGLLESCSRVVQQGAASPPCLPVAV
CCCEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
ETALAALDLQGVSDRRLGTLDAVNAQRAMIARALCQVAAAPYCPCRQRRDNGILLLDLEP
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEECCH
LAHDQEQRLLADLGAASRRHRLCIVPVVSPCDASLAHCDRVWWMDGGSRRADLSPSVRHV
HCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHCEEEEECCCCCCCCCCHHHHHH
LRVQVSSAERTRPNAPHPNDAAP
HHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLSLFNTALEGTPSLRPFSDRLVPGELLGICGPHGAGKSTLIGLLAGLYRPTRGSICLDG
CCCHHHHHHCCCCCCCCCHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCEEECC
QPLHCWPSAYRAQRIAHVIAPPRSLADWRVRDLVGLGLLESCSRVVQQGAASPPCLPVAV
CCCEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
ETALAALDLQGVSDRRLGTLDAVNAQRAMIARALCQVAAAPYCPCRQRRDNGILLLDLEP
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEECCH
LAHDQEQRLLADLGAASRRHRLCIVPVVSPCDASLAHCDRVWWMDGGSRRADLSPSVRHV
HCCCHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHCEEEEECCCCCCCCCCHHHHHH
LRVQVSSAERTRPNAPHPNDAAP
HHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron (III) hydroxamate [Periplasm]; H2O [C]

Specific reaction: ATP + iron (III) hydroxamate [Periplasm] + H2O = ADP + phosphate + iron (III) hydroxamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA