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The map label for this gene is cmoA

Identifier: 92114665

GI number: 92114665

Start: 2858482

End: 2859294

Strand: Direct

Name: cmoA

Synonym: Csal_2547

Alternate gene names: 92114665

Gene position: 2858482-2859294 (Clockwise)

Preceding gene: 92114658

Following gene: 92114666

Centisome position: 77.33

GC content: 63.47

Gene sequence:

>813_bases
ATGACGCGGCGCGTACAATATCGCCACTTCCTGTGGCCTCGGCCACGCCTCGACGCGATTGACTGGCTCATGAGTGACGC
ATCTTACCGTGACGCAATCTTTTCGACACCCCTGGACCGGGTGGCCAATTTTTCCTTCGATGAAAAGGTCGTCGCCTGCT
TTCCCGACATGATTCGCCGCTCGGTACCCGGCTATGGTCAGATCCTGGGCATGCTGGGCCTGATCGCCGAACGCCACCTG
CGCTTCGGCGCTCACGTCTATGACCTGGGCTGCTCGCTGGGCGCCGTGACCCTGGCGCTCGCCGGACGCTTGCCGCCGGA
TGCCTTCACCCTGACCGGCGTCGACCTGTCGCCGACGATGGTCGCCCGGGCACGTGAAACGCTCGGCGAGGAATGCCCCG
ATCATCGCATCGATATCGTCGAGGGCGATATCCGCCATGTCGACTACCGACCCGCCGGCATGATCGTGCTCAACTTCACG
TTGCAGTTCCTGCCCCCCGAGGACCGTCGCGCAGTCATCGAGCGCCTTTACGCCGCCCTCGAGCCCGGCGGCGTGCTGGT
GCTTTCCGAGAAGATCGTGCTGCCCGACGAGCAGGAAAACGCCTGGCTGGTGGAACGCTACCACGATTTCAAGCGCGCCA
ACGGCTATAGCGACATGGAAATCAGCCAGAAGCGCACCGCGCTGGAAAACGTGCTGGTGCCGGACACCCTCGACGCGCAC
CACGAGCGCCTGCACGAGGCCGGCTTCACCCGTGTCAGCACCTGGTTCCAGTATCTCAACTTCGCCTCGATGGTCGCCTT
CAAGGATGCCTGA

Upstream 100 bases:

>100_bases
AATGATGGATCATGGTTGACTGGGACATGACTCGTGCTCTCCTTGACAAGCTCGCTGACGGCCCGCGGATGCCGCGAGTG
GGCCCTGCGGATGCAGAGCC

Downstream 100 bases:

>100_bases
TCGCTCTCTGCCCCCTGCCCAGCGGGCCCTGTTCGATGCCCTGCTCGATCACGGCCTGAGCGAATGGGTCGCCCGCCTGC
CCGCGCAACTCGCCGATGGC

Product: methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTRRVQYRHFLWPRPRLDAIDWLMSDASYRDAIFSTPLDRVANFSFDEKVVACFPDMIRRSVPGYGQILGMLGLIAERHL
RFGAHVYDLGCSLGAVTLALAGRLPPDAFTLTGVDLSPTMVARARETLGEECPDHRIDIVEGDIRHVDYRPAGMIVLNFT
LQFLPPEDRRAVIERLYAALEPGGVLVLSEKIVLPDEQENAWLVERYHDFKRANGYSDMEISQKRTALENVLVPDTLDAH
HERLHEAGFTRVSTWFQYLNFASMVAFKDA

Sequences:

>Translated_270_residues
MTRRVQYRHFLWPRPRLDAIDWLMSDASYRDAIFSTPLDRVANFSFDEKVVACFPDMIRRSVPGYGQILGMLGLIAERHL
RFGAHVYDLGCSLGAVTLALAGRLPPDAFTLTGVDLSPTMVARARETLGEECPDHRIDIVEGDIRHVDYRPAGMIVLNFT
LQFLPPEDRRAVIERLYAALEPGGVLVLSEKIVLPDEQENAWLVERYHDFKRANGYSDMEISQKRTALENVLVPDTLDAH
HERLHEAGFTRVSTWFQYLNFASMVAFKDA
>Mature_269_residues
TRRVQYRHFLWPRPRLDAIDWLMSDASYRDAIFSTPLDRVANFSFDEKVVACFPDMIRRSVPGYGQILGMLGLIAERHLR
FGAHVYDLGCSLGAVTLALAGRLPPDAFTLTGVDLSPTMVARARETLGEECPDHRIDIVEGDIRHVDYRPAGMIVLNFTL
QFLPPEDRRAVIERLYAALEPGGVLVLSEKIVLPDEQENAWLVERYHDFKRANGYSDMEISQKRTALENVLVPDTLDAHH
ERLHEAGFTRVSTWFQYLNFASMVAFKDA

Specific function: Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U)

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. CmoA family

Homologues:

Organism=Escherichia coli, GI1788177, Length=241, Percent_Identity=48.9626556016597, Blast_Score=256, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CMOA_CHRSD (Q1QUG4)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_574593.1
- ProteinModelPortal:   Q1QUG4
- SMR:   Q1QUG4
- STRING:   Q1QUG4
- GeneID:   4026128
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_2547
- NMPDR:   fig|290398.4.peg.1796
- eggNOG:   COG0500
- HOGENOM:   HBG296860
- OMA:   YSELEVS
- ProtClustDB:   CLSK839536
- BioCyc:   CSAL290398:CSAL_2547-MONOMER
- HAMAP:   MF_01589
- InterPro:   IPR013216
- InterPro:   IPR005271
- PIRSF:   PIRSF006325
- TIGRFAMs:   TIGR00740

Pfam domain/function: PF08241 Methyltransf_11

EC number: NA

Molecular weight: Translated: 30736; Mature: 30604

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: BINDING 65-65 BINDING 115-115 BINDING 158-158 BINDING 225-225

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRVQYRHFLWPRPRLDAIDWLMSDASYRDAIFSTPLDRVANFSFDEKVVACFPDMIRR
CCCCCCHHHHCCCCCCHHHHHHHHCCCHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHH
SVPGYGQILGMLGLIAERHLRFGAHVYDLGCSLGAVTLALAGRLPPDAFTLTGVDLSPTM
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHCCCCCCCEEEECCCCCHHH
VARARETLGEECPDHRIDIVEGDIRHVDYRPAGMIVLNFTLQFLPPEDRRAVIERLYAAL
HHHHHHHHHHCCCCCCEEEEECCCEEECCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHC
EPGGVLVLSEKIVLPDEQENAWLVERYHDFKRANGYSDMEISQKRTALENVLVPDTLDAH
CCCCEEEEECEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHH
HERLHEAGFTRVSTWFQYLNFASMVAFKDA
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TRRVQYRHFLWPRPRLDAIDWLMSDASYRDAIFSTPLDRVANFSFDEKVVACFPDMIRR
CCCCCHHHHCCCCCCHHHHHHHHCCCHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHH
SVPGYGQILGMLGLIAERHLRFGAHVYDLGCSLGAVTLALAGRLPPDAFTLTGVDLSPTM
CCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHHHHHHCCCCCCCEEEECCCCCHHH
VARARETLGEECPDHRIDIVEGDIRHVDYRPAGMIVLNFTLQFLPPEDRRAVIERLYAAL
HHHHHHHHHHCCCCCCEEEEECCCEEECCCCCCEEEEEEEEEECCCHHHHHHHHHHHHHC
EPGGVLVLSEKIVLPDEQENAWLVERYHDFKRANGYSDMEISQKRTALENVLVPDTLDAH
CCCCEEEEECEEECCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHH
HERLHEAGFTRVSTWFQYLNFASMVAFKDA
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA