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The map label for this gene is ppa [H]

Identifier: 92114508

GI number: 92114508

Start: 2680475

End: 2681035

Strand: Direct

Name: ppa [H]

Synonym: Csal_2390

Alternate gene names: 92114508

Gene position: 2680475-2681035 (Clockwise)

Preceding gene: 92114501

Following gene: 92114512

Centisome position: 72.51

GC content: 64.88

Gene sequence:

>561_bases
TTGCTGTTCACCGCGTCCGCCCAGGCGCAGCCGAACGTCTTCGACTATCCGCAGCCCGATGATGCGCCGGACAGCTTCCA
CGTGGTCAACGAGATCCCCGCCGGGAGCTTCACCAAGTACGAGATCAATGCCGAGCACGGCCAGTTGATCGTCGACCGTT
ATGTCTCGATGCCGGTCCGCTACCCGGCCAACTACGGCTCCATCACCAGCTCGGCGGGTGGCGATGGCGACCCGCTGGAC
GCGCTGGTGCTGACCCGCGACAGCATCTATCCCGGTGCCGTGATCGAGGTCCGGGCCATCGGTGTGCTGCGCATGGTCGA
CGACGGCGAAGCCGACGACAAGATCATCGCCGTCCCCACCGACGCCGTGGATCCCAGCTACGCCGATGTCGAGGGCATCG
AGGATCTCCCGGCCATGCAGACCGAGCGGCTCAATGCCTTCTTCCGCGTTTACAAGGACCTGCCGGAGGGCGGCGATATC
GAATTGAACGGCTTCGGCGATGCCGGCGAGGCGCGTGACATCCTCTCCCGAGCCTTTGACGCCTACCAGGCCCAGCAGTA
A

Upstream 100 bases:

>100_bases
CCTGTGTCATCGTCCGACGGATAGGCTGGGGGCCTCCCTCTTCTCACCCACAGCGCGAGGTCTCATGAACGTCACTGCCC
CTTTCCTGATCGCCGCCGGC

Downstream 100 bases:

>100_bases
CGAAGACCGATCCTGAAAGACCAACGGCGCCCCGTGGGGCGCCGTTGGCATTTGCTTCGAACGTGCATTCCAGAGTGCTT
CACTAATAGAGGCTTACGGC

Product: inorganic diphosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MLFTASAQAQPNVFDYPQPDDAPDSFHVVNEIPAGSFTKYEINAEHGQLIVDRYVSMPVRYPANYGSITSSAGGDGDPLD
ALVLTRDSIYPGAVIEVRAIGVLRMVDDGEADDKIIAVPTDAVDPSYADVEGIEDLPAMQTERLNAFFRVYKDLPEGGDI
ELNGFGDAGEARDILSRAFDAYQAQQ

Sequences:

>Translated_186_residues
MLFTASAQAQPNVFDYPQPDDAPDSFHVVNEIPAGSFTKYEINAEHGQLIVDRYVSMPVRYPANYGSITSSAGGDGDPLD
ALVLTRDSIYPGAVIEVRAIGVLRMVDDGEADDKIIAVPTDAVDPSYADVEGIEDLPAMQTERLNAFFRVYKDLPEGGDI
ELNGFGDAGEARDILSRAFDAYQAQQ
>Mature_186_residues
MLFTASAQAQPNVFDYPQPDDAPDSFHVVNEIPAGSFTKYEINAEHGQLIVDRYVSMPVRYPANYGSITSSAGGDGDPLD
ALVLTRDSIYPGAVIEVRAIGVLRMVDDGEADDKIIAVPTDAVDPSYADVEGIEDLPAMQTERLNAFFRVYKDLPEGGDI
ELNGFGDAGEARDILSRAFDAYQAQQ

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Homo sapiens, GI11056044, Length=194, Percent_Identity=31.4432989690722, Blast_Score=70, Evalue=8e-13,
Organism=Escherichia coli, GI1790673, Length=170, Percent_Identity=37.6470588235294, Blast_Score=123, Evalue=7e-30,
Organism=Saccharomyces cerevisiae, GI6319483, Length=188, Percent_Identity=29.7872340425532, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 20164; Mature: 20164

Theoretical pI: Translated: 3.85; Mature: 3.85

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFTASAQAQPNVFDYPQPDDAPDSFHVVNEIPAGSFTKYEINAEHGQLIVDRYVSMPVR
CEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCEEEEHHHCCCEE
YPANYGSITSSAGGDGDPLDALVLTRDSIYPGAVIEVRAIGVLRMVDDGEADDKIIAVPT
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEEEEEEECCCCCCCEEEEECC
DAVDPSYADVEGIEDLPAMQTERLNAFFRVYKDLPEGGDIELNGFGDAGEARDILSRAFD
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHH
AYQAQQ
HHHCCC
>Mature Secondary Structure
MLFTASAQAQPNVFDYPQPDDAPDSFHVVNEIPAGSFTKYEINAEHGQLIVDRYVSMPVR
CEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCCCCEEEEHHHCCCEE
YPANYGSITSSAGGDGDPLDALVLTRDSIYPGAVIEVRAIGVLRMVDDGEADDKIIAVPT
CCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEEEEEEECCCCCCCEEEEECC
DAVDPSYADVEGIEDLPAMQTERLNAFFRVYKDLPEGGDIELNGFGDAGEARDILSRAFD
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHH
AYQAQQ
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9055427 [H]