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The map label for this gene is kdsC [H]

Identifier: 92114344

GI number: 92114344

Start: 2494952

End: 2495494

Strand: Direct

Name: kdsC [H]

Synonym: Csal_2222

Alternate gene names: 92114344

Gene position: 2494952-2495494 (Clockwise)

Preceding gene: 92114343

Following gene: 92114345

Centisome position: 67.49

GC content: 68.32

Gene sequence:

>543_bases
ATGACACGATCCAGCGAATGGCAAGACAAGGCGCGCCGCATCCGCTTGCTGGCCCTGGATGTGGACGGCGTGCTCACCGA
CGGCACGCTCCACTTTCACAGCGACGGTCAGGAGACCAAGAGCTTCAACATCCTCGACGGCCTGGGCATCAAGATGCTGC
AACGAAGCGGCGTCCAGGTGGCCTTGATCACGGGGCGCAAGTCGCCCATGGTCACGCGCCGTGCCGAGGCGCTCGGCATT
GCCCACGTCCATCAGGGACGCGAGGACAAGCTGATCGCGCTGCGCGCCCTGTGCGAGGCACTCGGCCTGCCCCTGGCCGA
CGTCGCCTACTGCGGCGACGACCTCCCGGACCTGGCCGCCATCCGTGCCGCCGGTCTGGGACTGAGCGTCCTCAATGCCC
CCGCATACGTGCGCGAGCATGCCGACTGGGTGCCCAACCGCCCGGGTGGCCAGGGCGCCGTGCGCGAGATCTGCGACGCA
CTGCTGGCCAGCCAGGGGAACTGGGATGCCAGCCTGGCGCCGTATCTCGACGACCTGGAGTGA

Upstream 100 bases:

>100_bases
TCGCATCACAGCCCTGGCCGTGGTCGACGACCAGGGCCATCCGGTCGGCGTCCTGCACATGCACGACCTGCTGGCCAGCG
GCGTCATCTGAGGAGAGTCC

Downstream 100 bases:

>100_bases
CGCCATGCCGACGTTCTTCTCTTCTCGCAAATGGACGCGCTTCGCGCTGCTGCTGATTCTGGTCGTGCTGGGCATCGGTC
TGGCCATCGTCGAGCAGCGC

Product: phosphatase kdsC

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MTRSSEWQDKARRIRLLALDVDGVLTDGTLHFHSDGQETKSFNILDGLGIKMLQRSGVQVALITGRKSPMVTRRAEALGI
AHVHQGREDKLIALRALCEALGLPLADVAYCGDDLPDLAAIRAAGLGLSVLNAPAYVREHADWVPNRPGGQGAVREICDA
LLASQGNWDASLAPYLDDLE

Sequences:

>Translated_180_residues
MTRSSEWQDKARRIRLLALDVDGVLTDGTLHFHSDGQETKSFNILDGLGIKMLQRSGVQVALITGRKSPMVTRRAEALGI
AHVHQGREDKLIALRALCEALGLPLADVAYCGDDLPDLAAIRAAGLGLSVLNAPAYVREHADWVPNRPGGQGAVREICDA
LLASQGNWDASLAPYLDDLE
>Mature_179_residues
TRSSEWQDKARRIRLLALDVDGVLTDGTLHFHSDGQETKSFNILDGLGIKMLQRSGVQVALITGRKSPMVTRRAEALGIA
HVHQGREDKLIALRALCEALGLPLADVAYCGDDLPDLAAIRAAGLGLSVLNAPAYVREHADWVPNRPGGQGAVREICDAL
LASQGNWDASLAPYLDDLE

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=154, Percent_Identity=27.9220779220779, Blast_Score=77, Evalue=7e-15,
Organism=Escherichia coli, GI2367202, Length=166, Percent_Identity=46.3855421686747, Blast_Score=147, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 19417; Mature: 19286

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSSEWQDKARRIRLLALDVDGVLTDGTLHFHSDGQETKSFNILDGLGIKMLQRSGVQV
CCCCCHHHHHHHEEEEEEEECCCEEECCEEEECCCCCCCCCEECHHHHHHHHHHHCCCEE
ALITGRKSPMVTRRAEALGIAHVHQGREDKLIALRALCEALGLPLADVAYCGDDLPDLAA
EEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHH
IRAAGLGLSVLNAPAYVREHADWVPNRPGGQGAVREICDALLASQGNWDASLAPYLDDLE
HHHHCCCHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TRSSEWQDKARRIRLLALDVDGVLTDGTLHFHSDGQETKSFNILDGLGIKMLQRSGVQV
CCCCHHHHHHHEEEEEEEECCCEEECCEEEECCCCCCCCCEECHHHHHHHHHHHCCCEE
ALITGRKSPMVTRRAEALGIAHVHQGREDKLIALRALCEALGLPLADVAYCGDDLPDLAA
EEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHH
IRAAGLGLSVLNAPAYVREHADWVPNRPGGQGAVREICDALLASQGNWDASLAPYLDDLE
HHHHCCCHHHHCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]