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The map label for this gene is pgsA [H]

Identifier: 92114256

GI number: 92114256

Start: 2402819

End: 2403367

Strand: Direct

Name: pgsA [H]

Synonym: Csal_2134

Alternate gene names: 92114256

Gene position: 2402819-2403367 (Clockwise)

Preceding gene: 92114255

Following gene: 92114258

Centisome position: 65.0

GC content: 61.38

Gene sequence:

>549_bases
ATGAACATTCCCAACCTATTGACGCTTGCTCGAATCGCGTGCATTCCGTTGCTGGTGATCGCCTTCTATCTCCCTTATGC
TTGGAGTTTGCTGCTGTGCGCCGGTCTGTTCGGGCTTGCCGCCGTTACCGATTGGCTCGACGGCTATCTGGCACGTCGCT
GGAACCAGAGCACTCCCTTCGGCGCCTTCCTCGACCCCGTGGCGGACAAGTTGATGGTCGCAGTCGCACTGGCATTGCTG
ATCGAACGCTTCGATACCGCCTGGCTGACGCTGCCGGGGCTGGTGATCATCGGCCGCGAGATCGTCATCTCGGCCTTGCG
CGAGTGGATGGCGGAGCTAGGCAAACGCGGCAGCGTCGCCGTTTCCTGGATCGGCAAGCTCAAGACCACGCTGCAAATGG
TCTCTCTGCTGCTGTTGCTGGGCTTTGCACCGGGCACCATGATCGCCAACGTGGGTGTGGTGCTGCTTTACGTCGCCGCC
GCGCTGACCCTGTGGTCGATGTACCAGTACATGCGTGCCGCCTGGCCGGAGCTCACGCGCTCAATGTGA

Upstream 100 bases:

>100_bases
ATGGCCACGACCATCCATCAAGCCTTGCATGGATGAGCCATGAGCGGAAAGATAGAATAATGCGGTTACCTCATTCACCA
GCCAGGACTTACGTCGCTCG

Downstream 100 bases:

>100_bases
GCATCCAGGATGAGGCGCATAAACGTTTGACATTCACAGACTTATCCTTATAATGCGTCCTCGAGTTCGGCGGGAATAGC
TCAGTGGTAGAGCATCGCCT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 182; Mature: 182

Protein sequence:

>182_residues
MNIPNLLTLARIACIPLLVIAFYLPYAWSLLLCAGLFGLAAVTDWLDGYLARRWNQSTPFGAFLDPVADKLMVAVALALL
IERFDTAWLTLPGLVIIGREIVISALREWMAELGKRGSVAVSWIGKLKTTLQMVSLLLLLGFAPGTMIANVGVVLLYVAA
ALTLWSMYQYMRAAWPELTRSM

Sequences:

>Translated_182_residues
MNIPNLLTLARIACIPLLVIAFYLPYAWSLLLCAGLFGLAAVTDWLDGYLARRWNQSTPFGAFLDPVADKLMVAVALALL
IERFDTAWLTLPGLVIIGREIVISALREWMAELGKRGSVAVSWIGKLKTTLQMVSLLLLLGFAPGTMIANVGVVLLYVAA
ALTLWSMYQYMRAAWPELTRSM
>Mature_182_residues
MNIPNLLTLARIACIPLLVIAFYLPYAWSLLLCAGLFGLAAVTDWLDGYLARRWNQSTPFGAFLDPVADKLMVAVALALL
IERFDTAWLTLPGLVIIGREIVISALREWMAELGKRGSVAVSWIGKLKTTLQMVSLLLLLGFAPGTMIANVGVVLLYVAA
ALTLWSMYQYMRAAWPELTRSM

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=174, Percent_Identity=62.0689655172414, Blast_Score=214, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6320059, Length=109, Percent_Identity=39.4495412844037, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20074; Mature: 20074

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIPNLLTLARIACIPLLVIAFYLPYAWSLLLCAGLFGLAAVTDWLDGYLARRWNQSTPF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GAFLDPVADKLMVAVALALLIERFDTAWLTLPGLVIIGREIVISALREWMAELGKRGSVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
VSWIGKLKTTLQMVSLLLLLGFAPGTMIANVGVVLLYVAAALTLWSMYQYMRAAWPELTR
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SM
CC
>Mature Secondary Structure
MNIPNLLTLARIACIPLLVIAFYLPYAWSLLLCAGLFGLAAVTDWLDGYLARRWNQSTPF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GAFLDPVADKLMVAVALALLIERFDTAWLTLPGLVIIGREIVISALREWMAELGKRGSVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
VSWIGKLKTTLQMVSLLLLLGFAPGTMIANVGVVLLYVAAALTLWSMYQYMRAAWPELTR
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SM
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA