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The map label for this gene is dinB [H]

Identifier: 92114193

GI number: 92114193

Start: 2340180

End: 2341226

Strand: Direct

Name: dinB [H]

Synonym: Csal_2071

Alternate gene names: 92114193

Gene position: 2340180-2341226 (Clockwise)

Preceding gene: 92114192

Following gene: 92114196

Centisome position: 63.31

GC content: 67.24

Gene sequence:

>1047_bases
ATGCGCAAGATCCTCCACGCCGACTGCGACTGCTTCTACGCCGCCGTGGAAATGCGCGACGACCCGGCGCTGCGCGACGT
CCCGCTGGCGATCGGCGGCAGCCCCGAGCAACGCGGTGTCGTCGCCACCTGCAATTATCCGGCGCGGGCCTTCGGCATCC
ATTCGGCGATGCCCATGGCCCGAGCCATGCGCCTGTGCCCTCACCTCACCCGCCTGGCGCCCGATTTTCCCAAGTACCGG
GAGGTGTCGGCGCGCATTCAAGCGCTGTTTCACGAACTGACCCCGCTGGTGGAACCGCTGTCGCTGGACGAGGCCTATCT
CGATGTCAGCGAGGTGACGCAATGCCAGGGAAGCGCGACCTGGATGGCTCGCTGGTTGAAGCAGGAAGCGCTGACACGCA
CGGGTATCGTGATTTCGGTGGGCGCGGCGCCCAGCAAGTTTCTCGCCAAGCTGGCGAGCGACTGGGACAAGCCCGACGGC
CTCTACGTGATCGCGCCGGAGGAAGTCGAACCCTTCCTGCTCGAACTGCCGGTCAAGCGCCTGCATGGGGTGGGACCGGC
GACGGCGGCCAAGCTCGAAGGCCTGGGCATCGTGACCTGCCGCGACTTGCGTGACTGGCCCCTCGACACCCTGCTCGAGC
GCTTCGGAAAGTTCGGACGACGCCTCTTCGAACTGGCCCGCGGGATCGACGAGCGCCCGGTGCAGATCGAGCGCGAGAGG
AAATCGGTCAGCGTGGAAACCACCTACCACCGTGACCTGCCGAACCTCGCCGCCTGCCACGACGCCCTGTCGCCGCTGAT
CGAGCGGTTGCGAGAGCGGCTGGCCCGCCATGGCACGCCGGCCATTCACAAATTGTTCGTCAAGGTACGCTTCGACGATT
TCAGCAGCACGACGCTGGAGGCATCGGGCCGCGAGGCGCAGACGACGCGCTTTCAGGCGTTGCTGGAGGGCGCCTGGGCG
CGTGGCGAGAGACCGGTGCGGCTGCTCGGTGTCGGCGTGCGACTGGCCCCCGAGGCCCAGCGTCGCCAGATGACGCTCTT
CGACTGA

Upstream 100 bases:

>100_bases
GACCTGCGTCACCAGGACCTGGAAATCGAAGGACTGGGCGTGGGGGTGATTCGCGGCGGCGGCGGCAACGGCCTGCACTG
AGGCCCCACTGGCCCACGCC

Downstream 100 bases:

>100_bases
GCGGCGTGCCTAGCCCGTCAACCAGCCGGTTTCGATGCACAGCGTCCATAGCCCGATGGCGATGAACAACAGGCTTGCGA
CACCATGAATCGTCTTGAGG

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MRKILHADCDCFYAAVEMRDDPALRDVPLAIGGSPEQRGVVATCNYPARAFGIHSAMPMARAMRLCPHLTRLAPDFPKYR
EVSARIQALFHELTPLVEPLSLDEAYLDVSEVTQCQGSATWMARWLKQEALTRTGIVISVGAAPSKFLAKLASDWDKPDG
LYVIAPEEVEPFLLELPVKRLHGVGPATAAKLEGLGIVTCRDLRDWPLDTLLERFGKFGRRLFELARGIDERPVQIERER
KSVSVETTYHRDLPNLAACHDALSPLIERLRERLARHGTPAIHKLFVKVRFDDFSSTTLEASGREAQTTRFQALLEGAWA
RGERPVRLLGVGVRLAPEAQRRQMTLFD

Sequences:

>Translated_348_residues
MRKILHADCDCFYAAVEMRDDPALRDVPLAIGGSPEQRGVVATCNYPARAFGIHSAMPMARAMRLCPHLTRLAPDFPKYR
EVSARIQALFHELTPLVEPLSLDEAYLDVSEVTQCQGSATWMARWLKQEALTRTGIVISVGAAPSKFLAKLASDWDKPDG
LYVIAPEEVEPFLLELPVKRLHGVGPATAAKLEGLGIVTCRDLRDWPLDTLLERFGKFGRRLFELARGIDERPVQIERER
KSVSVETTYHRDLPNLAACHDALSPLIERLRERLARHGTPAIHKLFVKVRFDDFSSTTLEASGREAQTTRFQALLEGAWA
RGERPVRLLGVGVRLAPEAQRRQMTLFD
>Mature_348_residues
MRKILHADCDCFYAAVEMRDDPALRDVPLAIGGSPEQRGVVATCNYPARAFGIHSAMPMARAMRLCPHLTRLAPDFPKYR
EVSARIQALFHELTPLVEPLSLDEAYLDVSEVTQCQGSATWMARWLKQEALTRTGIVISVGAAPSKFLAKLASDWDKPDG
LYVIAPEEVEPFLLELPVKRLHGVGPATAAKLEGLGIVTCRDLRDWPLDTLLERFGKFGRRLFELARGIDERPVQIERER
KSVSVETTYHRDLPNLAACHDALSPLIERLRERLARHGTPAIHKLFVKVRFDDFSSTTLEASGREAQTTRFQALLEGAWA
RGERPVRLLGVGVRLAPEAQRRQMTLFD

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=328, Percent_Identity=30.7926829268293, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI7706681, Length=329, Percent_Identity=30.6990881458967, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI154350220, Length=314, Percent_Identity=29.6178343949045, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI7705344, Length=108, Percent_Identity=46.2962962962963, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI5729982, Length=326, Percent_Identity=25.1533742331288, Blast_Score=86, Evalue=3e-17,
Organism=Escherichia coli, GI1786425, Length=349, Percent_Identity=48.9971346704871, Blast_Score=318, Evalue=3e-88,
Organism=Escherichia coli, GI1787432, Length=230, Percent_Identity=29.1304347826087, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI193205700, Length=362, Percent_Identity=28.1767955801105, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI17537959, Length=259, Percent_Identity=30.5019305019305, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI115534089, Length=128, Percent_Identity=32.03125, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6324921, Length=288, Percent_Identity=25.6944444444444, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19923006, Length=323, Percent_Identity=27.8637770897833, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI21355641, Length=383, Percent_Identity=28.7206266318538, Blast_Score=127, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24644984, Length=383, Percent_Identity=28.7206266318538, Blast_Score=127, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24668444, Length=119, Percent_Identity=35.2941176470588, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39027; Mature: 39027

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKILHADCDCFYAAVEMRDDPALRDVPLAIGGSPEQRGVVATCNYPARAFGIHSAMPMA
CCCCHHCCCHHHHHHHCCCCCCCCCCCCEEECCCCCCCCEEEECCCCHHHHHHHHHHHHH
RAMRLCPHLTRLAPDFPKYREVSARIQALFHELTPLVEPLSLDEAYLDVSEVTQCQGSAT
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHCCCHH
WMARWLKQEALTRTGIVISVGAAPSKFLAKLASDWDKPDGLYVIAPEEVEPFLLELPVKR
HHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHCCHHH
LHGVGPATAAKLEGLGIVTCRDLRDWPLDTLLERFGKFGRRLFELARGIDERPVQIERER
HCCCCCHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHH
KSVSVETTYHRDLPNLAACHDALSPLIERLRERLARHGTPAIHKLFVKVRFDDFSSTTLE
HCEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEEECCCCCCEEC
ASGREAQTTRFQALLEGAWARGERPVRLLGVGVRLAPEAQRRQMTLFD
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCEECCHHHHCCCCCCC
>Mature Secondary Structure
MRKILHADCDCFYAAVEMRDDPALRDVPLAIGGSPEQRGVVATCNYPARAFGIHSAMPMA
CCCCHHCCCHHHHHHHCCCCCCCCCCCCEEECCCCCCCCEEEECCCCHHHHHHHHHHHHH
RAMRLCPHLTRLAPDFPKYREVSARIQALFHELTPLVEPLSLDEAYLDVSEVTQCQGSAT
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHHHCCCHH
WMARWLKQEALTRTGIVISVGAAPSKFLAKLASDWDKPDGLYVIAPEEVEPFLLELPVKR
HHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHCCHHH
LHGVGPATAAKLEGLGIVTCRDLRDWPLDTLLERFGKFGRRLFELARGIDERPVQIERER
HCCCCCHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHH
KSVSVETTYHRDLPNLAACHDALSPLIERLRERLARHGTPAIHKLFVKVRFDDFSSTTLE
HCEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEEECCCCCCEEC
ASGREAQTTRFQALLEGAWARGERPVRLLGVGVRLAPEAQRRQMTLFD
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCEECCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA