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The map label for this gene is fdoI [H]

Identifier: 92114040

GI number: 92114040

Start: 2178547

End: 2179590

Strand: Direct

Name: fdoI [H]

Synonym: Csal_1917

Alternate gene names: 92114040

Gene position: 2178547-2179590 (Clockwise)

Preceding gene: 92114039

Following gene: 92114041

Centisome position: 58.93

GC content: 63.6

Gene sequence:

>1044_bases
ATGCACACACTCATGCAATGCCTATGGCGGCTGCGTATGATCGGTGCGGTGCTGTTGCTGGCGGTGCTGGCCGCCGGCCT
GGCCCCACCCGCAACGGCGGCCGAACCCGATGAAGAGATCGGGCAGGCGGTCGGCACGGTCGACGCCGACACCTGGCGGC
AGGTCAAGAGTGGCGAGAACTTCATCGATTCGCGCCACGACTCGACCTACAACCTGATCAACCCCAGCGGCGAGACCTGG
CGCCAGGTCCGCAACGAGTGGATTTCTCCGGCCGGTCTCATCGCGGTCGGCGGCATGCTCGCCATCCTGGTGATCTTCTA
CCTGATCGTCGGTCGCAACGACCTCGACCACGAGCGCACGGGACGCAAGATCCTGCGCTGGACGGTACTCGAGCGCTCGC
TGCACTGGACCGTGGCCACGCTGTTCATCGCTCTCTCGCTGACCGGCCTGAACCTGCTGTACGGCAAGTTCGTGTTCCGT
CACATCTTCGGCGATGTCTTCTGGGCCAACATGATCATGGGCTCCAAGCTGATCCACAACTACGCGGGCCCGGTCTTCGG
CATCCTGCTGATCGTCATGCTCGCCAAGTGGCTCAAGGTCAACCTGCCCAAGAAGCACGACTGGGAGTGGTTCAAGCAAG
GCGGCGGCATGGTCGGCAACAAGCACCCGGACGCAGGCTTCGCCAACGCCGGCGAGAAGGTCTGGTTCTGGTTGCTGGCC
AGCGTGGGCCTGGTGGTCGTGGTCAGCGGCCTCGTGCTCGACTTCCCGATCTTCGGACAGACGCGTGACAACATGCAGTG
GGCCAACATGTTCCATGCCGTGACCTCGTTGATCCTGATGACCGTCGCGCTCGGCCACATCTACATCGGGACCTTGGGGA
CCGAGGGCGCCCTGGAAGGCATGGCCACCGGCTATGTCGACGAAACCTGGGCCAAGCAGCACCACAATTTGTGGTACGAA
GAAGTCAAGGCCAATGCCGGCCAGCCTCAGCAAAGCGACCCTCCCGTCGCGGACGACACGGCGACGGCTCACCGGCCCAA
CTGA

Upstream 100 bases:

>100_bases
TCGAAAAAGCGCAGAATGCGGGCCCAGATGTCTCGGCCAATCTCGACGAGATGGCCTACGACGCCACCCGCGCCACACGT
GAAGGGTGAGGAGAGCGCTC

Downstream 100 bases:

>100_bases
ACGCCATGCCGTACCCCGACAGCAAGACGACACCGCCCCCGGGCGGTGTCGCTCTTTGATATGATGCAGGCAGATGTCCT
ACCACCCCATAGATCCCGCG

Product: formate dehydrogenase gamma subunit

Products: CO2; NADH

Alternate protein names: Aerobic formate dehydrogenase cytochrome b556 subunit; FDH-Z subunit gamma; Formate dehydrogenase-O subunit gamma [H]

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MHTLMQCLWRLRMIGAVLLLAVLAAGLAPPATAAEPDEEIGQAVGTVDADTWRQVKSGENFIDSRHDSTYNLINPSGETW
RQVRNEWISPAGLIAVGGMLAILVIFYLIVGRNDLDHERTGRKILRWTVLERSLHWTVATLFIALSLTGLNLLYGKFVFR
HIFGDVFWANMIMGSKLIHNYAGPVFGILLIVMLAKWLKVNLPKKHDWEWFKQGGGMVGNKHPDAGFANAGEKVWFWLLA
SVGLVVVVSGLVLDFPIFGQTRDNMQWANMFHAVTSLILMTVALGHIYIGTLGTEGALEGMATGYVDETWAKQHHNLWYE
EVKANAGQPQQSDPPVADDTATAHRPN

Sequences:

>Translated_347_residues
MHTLMQCLWRLRMIGAVLLLAVLAAGLAPPATAAEPDEEIGQAVGTVDADTWRQVKSGENFIDSRHDSTYNLINPSGETW
RQVRNEWISPAGLIAVGGMLAILVIFYLIVGRNDLDHERTGRKILRWTVLERSLHWTVATLFIALSLTGLNLLYGKFVFR
HIFGDVFWANMIMGSKLIHNYAGPVFGILLIVMLAKWLKVNLPKKHDWEWFKQGGGMVGNKHPDAGFANAGEKVWFWLLA
SVGLVVVVSGLVLDFPIFGQTRDNMQWANMFHAVTSLILMTVALGHIYIGTLGTEGALEGMATGYVDETWAKQHHNLWYE
EVKANAGQPQQSDPPVADDTATAHRPN
>Mature_347_residues
MHTLMQCLWRLRMIGAVLLLAVLAAGLAPPATAAEPDEEIGQAVGTVDADTWRQVKSGENFIDSRHDSTYNLINPSGETW
RQVRNEWISPAGLIAVGGMLAILVIFYLIVGRNDLDHERTGRKILRWTVLERSLHWTVATLFIALSLTGLNLLYGKFVFR
HIFGDVFWANMIMGSKLIHNYAGPVFGILLIVMLAKWLKVNLPKKHDWEWFKQGGGMVGNKHPDAGFANAGEKVWFWLLA
SVGLVVVVSGLVLDFPIFGQTRDNMQWANMFHAVTSLILMTVALGHIYIGTLGTEGALEGMATGYVDETWAKQHHNLWYE
EVKANAGQPQQSDPPVADDTATAHRPN

Specific function: Allows to use formate as major electron donor during aerobic respiration. Subunit gamma is probably the cytochrome b556(FDO) component of the formate dehydrogenase [H]

COG id: COG2864

COG function: function code C; Cytochrome b subunit of formate dehydrogenase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the formate dehydrogenase gamma subunit family [H]

Homologues:

Organism=Escherichia coli, GI1790325, Length=215, Percent_Identity=29.7674418604651, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787750, Length=222, Percent_Identity=27.027027027027, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005797
- InterPro:   IPR016174
- InterPro:   IPR006471 [H]

Pfam domain/function: PF00033 Cytochrom_B_N [H]

EC number: 1.2.1.2

Molecular weight: Translated: 38563; Mature: 38563

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTLMQCLWRLRMIGAVLLLAVLAAGLAPPATAAEPDEEIGQAVGTVDADTWRQVKSGEN
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHCCCH
FIDSRHDSTYNLINPSGETWRQVRNEWISPAGLIAVGGMLAILVIFYLIVGRNDLDHERT
HHHCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
GRKILRWTVLERSLHWTVATLFIALSLTGLNLLYGKFVFRHIFGDVFWANMIMGSKLIHN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YAGPVFGILLIVMLAKWLKVNLPKKHDWEWFKQGGGMVGNKHPDAGFANAGEKVWFWLLA
HCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
SVGLVVVVSGLVLDFPIFGQTRDNMQWANMFHAVTSLILMTVALGHIYIGTLGTEGALEG
HHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
MATGYVDETWAKQHHNLWYEEVKANAGQPQQSDPPVADDTATAHRPN
HHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure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HHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate; NAD+

Specific reaction: formate + NAD+ = CO2 + NADH

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]