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The map label for this gene is mrdB [H]

Identifier: 92113670

GI number: 92113670

Start: 1758653

End: 1759798

Strand: Direct

Name: mrdB [H]

Synonym: Csal_1546

Alternate gene names: 92113670

Gene position: 1758653-1759798 (Clockwise)

Preceding gene: 92113669

Following gene: 92113671

Centisome position: 47.57

GC content: 63.18

Gene sequence:

>1146_bases
TTGAAGGGACTTGAGTGGCGTCGATTCAGTCCGGCATCGTCCGATGGCATGGGGCGCAAGCGTTCGTTGTGGTCGCGCCT
GCATCTCGACCCCTGGCTGCTGCTGCTGCTGCTGACCTTGATGGGGGCGGGACTGGTCGTCCTGTACAGCGCCAGCGGCA
TGAGTCCGGCGGTCACCATGGGACAGGGCATGCGCTTCGGGGTTGCCTTGCTGGCCATGTTCATGGTCGCCCAGTTTTCG
CCGGGCACCCTGTACCGCTGGACGCCGTTGGCCTATTGCACGGGCGTGGCGATGCTGCTGGCGGTGGAGATCATGGGCGA
TATCGGCATGGGGGCGCAGCGTTGGCTGGAAATCCCCGGCGTGATCCGCTTTCAGCCGTCGGAATTGATGAAGCTGGCGG
TCCCCATGATGGTCGCGGCTTATCTCTGCAAGCGCCCGCTGCCGCCCAATACCCGCGATTTGCTGGTGTGCGGCTTCATC
ATCGGCTTCCCGGTGATGCTGATCATGCGTCAGCCCGACCTGGGAACGTCGCTGCTGGTGGCGTGTGCCGCGGTCTTCGT
CATTTTCCTCGCCGGGCTGTCGTGGCGAGTGATCGCCTTGCTGGGGGCACTGGCGGCGTCGGCCTTGCCGCTTTTGTGGT
TCAACATGCATGAATATCAGCGCCAGCGCGTGCTGACGTTCCTGAATCCGGAAAGCGATCCGCTGGGCGCGGGCTGGAAC
ATCATCCAGTCGAAGACCGCCATTGGCAGTGGCGGGGTCTTCGGCAAGGGATGGGGACTGGGGACACAGTCCCAGCTGGA
GTTCCTGCCCGAACGTCACACCGACTTCATCGTCGCCGTGCTCGGGGAAGAGTGGGGGCTGATCGGCATGCTGGTCTTCC
TGGCGCTCTATGTCCTGATCGTGGGGCGCGGACTGTTTCTCGCCAATACCGCGCAGAACACCTATGGACGCCTGGTGGGG
GGCAGCATCGTGCTGACGTTTTTCATCTACGTCTTCGTCAATATCGGCATGGTCAGCGGCATTCTGCCCGTCGTCGGAGT
GCCGTTGCCGCTGGTCAGTTTCGGGGGGACGTCCAGCGTGACCTTGCTGATCGGTTTCGGTATCCTCATGTCCGTTCACA
GCCACCGGCGGTTGCTGCCGCGCTAG

Upstream 100 bases:

>100_bases
CACGCCGCCGGACTGGCCCGTGCGCTGGCGGACGAGTGGCTTTTGCCCGATGACGAGAACACCCACCAGGCCGAGAAACT
GATCGAGGAGGACGTCGAAG

Downstream 100 bases:

>100_bases
GCATGCCAAGACACGCAAGGATAGCGACCACATACCAGGGCCAAGGAGCCTGTGCCTGATGAAGCGGAACATGACACGCG
CCCAGCGAAAAAAATTCGGC

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKGLEWRRFSPASSDGMGRKRSLWSRLHLDPWLLLLLLTLMGAGLVVLYSASGMSPAVTMGQGMRFGVALLAMFMVAQFS
PGTLYRWTPLAYCTGVAMLLAVEIMGDIGMGAQRWLEIPGVIRFQPSELMKLAVPMMVAAYLCKRPLPPNTRDLLVCGFI
IGFPVMLIMRQPDLGTSLLVACAAVFVIFLAGLSWRVIALLGALAASALPLLWFNMHEYQRQRVLTFLNPESDPLGAGWN
IIQSKTAIGSGGVFGKGWGLGTQSQLEFLPERHTDFIVAVLGEEWGLIGMLVFLALYVLIVGRGLFLANTAQNTYGRLVG
GSIVLTFFIYVFVNIGMVSGILPVVGVPLPLVSFGGTSSVTLLIGFGILMSVHSHRRLLPR

Sequences:

>Translated_381_residues
MKGLEWRRFSPASSDGMGRKRSLWSRLHLDPWLLLLLLTLMGAGLVVLYSASGMSPAVTMGQGMRFGVALLAMFMVAQFS
PGTLYRWTPLAYCTGVAMLLAVEIMGDIGMGAQRWLEIPGVIRFQPSELMKLAVPMMVAAYLCKRPLPPNTRDLLVCGFI
IGFPVMLIMRQPDLGTSLLVACAAVFVIFLAGLSWRVIALLGALAASALPLLWFNMHEYQRQRVLTFLNPESDPLGAGWN
IIQSKTAIGSGGVFGKGWGLGTQSQLEFLPERHTDFIVAVLGEEWGLIGMLVFLALYVLIVGRGLFLANTAQNTYGRLVG
GSIVLTFFIYVFVNIGMVSGILPVVGVPLPLVSFGGTSSVTLLIGFGILMSVHSHRRLLPR
>Mature_381_residues
MKGLEWRRFSPASSDGMGRKRSLWSRLHLDPWLLLLLLTLMGAGLVVLYSASGMSPAVTMGQGMRFGVALLAMFMVAQFS
PGTLYRWTPLAYCTGVAMLLAVEIMGDIGMGAQRWLEIPGVIRFQPSELMKLAVPMMVAAYLCKRPLPPNTRDLLVCGFI
IGFPVMLIMRQPDLGTSLLVACAAVFVIFLAGLSWRVIALLGALAASALPLLWFNMHEYQRQRVLTFLNPESDPLGAGWN
IIQSKTAIGSGGVFGKGWGLGTQSQLEFLPERHTDFIVAVLGEEWGLIGMLVFLALYVLIVGRGLFLANTAQNTYGRLVG
GSIVLTFFIYVFVNIGMVSGILPVVGVPLPLVSFGGTSSVTLLIGFGILMSVHSHRRLLPR

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=364, Percent_Identity=53.021978021978, Blast_Score=353, Evalue=8e-99,
Organism=Escherichia coli, GI1786277, Length=379, Percent_Identity=32.1899736147757, Blast_Score=155, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41434; Mature: 41434

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGLEWRRFSPASSDGMGRKRSLWSRLHLDPWLLLLLLTLMGAGLVVLYSASGMSPAVTM
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHH
GQGMRFGVALLAMFMVAQFSPGTLYRWTPLAYCTGVAMLLAVEIMGDIGMGAQRWLEIPG
CCCHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
VIRFQPSELMKLAVPMMVAAYLCKRPLPPNTRDLLVCGFIIGFPVMLIMRQPDLGTSLLV
EEEECHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ACAAVFVIFLAGLSWRVIALLGALAASALPLLWFNMHEYQRQRVLTFLNPESDPLGAGWN
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
IIQSKTAIGSGGVFGKGWGLGTQSQLEFLPERHTDFIVAVLGEEWGLIGMLVFLALYVLI
HHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
VGRGLFLANTAQNTYGRLVGGSIVLTFFIYVFVNIGMVSGILPVVGVPLPLVSFGGTSSV
HCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCHH
TLLIGFGILMSVHSHRRLLPR
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKGLEWRRFSPASSDGMGRKRSLWSRLHLDPWLLLLLLTLMGAGLVVLYSASGMSPAVTM
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECCCCCCHHHH
GQGMRFGVALLAMFMVAQFSPGTLYRWTPLAYCTGVAMLLAVEIMGDIGMGAQRWLEIPG
CCCHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
VIRFQPSELMKLAVPMMVAAYLCKRPLPPNTRDLLVCGFIIGFPVMLIMRQPDLGTSLLV
EEEECHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
ACAAVFVIFLAGLSWRVIALLGALAASALPLLWFNMHEYQRQRVLTFLNPESDPLGAGWN
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCH
IIQSKTAIGSGGVFGKGWGLGTQSQLEFLPERHTDFIVAVLGEEWGLIGMLVFLALYVLI
HHHHCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHH
VGRGLFLANTAQNTYGRLVGGSIVLTFFIYVFVNIGMVSGILPVVGVPLPLVSFGGTSSV
HCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCHH
TLLIGFGILMSVHSHRRLLPR
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]