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The map label for this gene is rlmH

Identifier: 92113668

GI number: 92113668

Start: 1756234

End: 1756701

Strand: Direct

Name: rlmH

Synonym: Csal_1544

Alternate gene names: 92113668

Gene position: 1756234-1756701 (Clockwise)

Preceding gene: 92113667

Following gene: 92113669

Centisome position: 47.51

GC content: 66.03

Gene sequence:

>468_bases
ATGAAACTCCGCGTTCTGGCCGTTGGAACGCGCATGCCCGACTGGGTGACACGAGGCGTCGACGAGTATCTCAAGCGGCT
GCCGCGGGATTTCAGCGTCGAGATCGTCGAGATCGCGCCCGGCAAACGCGGCAAGAATGCCGACGTGGCGCGGGCGATTC
AGGGCGAGGGCAATGCCATGCTGGCCAAGCTGCGCGATCAGGAGCGTGTCATCGCGCTGGCCGTCGACGGACAACACTGG
AGTACCGAGCGCCTCGCCGCCAATGCCGATCATTGGCGGCAGGACGGGCGCGATGTGGCACTGCTGGTGGGCGGGCCGGA
CGGGCTCGACCCCCGCTTGCTGTCGCGCGTCGAACAGCGCTGGTCGCTATCGGCACTGACGCTGCCGCATCCGCTGGTGC
GCATTCTATTGGCCGAGCAGCTGTATCGTGCTTGGACCTTGCTGGCCGGGCACCCTTATCACCGATGA

Upstream 100 bases:

>100_bases
TGCTGCCCGAGACGCGTCAGTTGTACGATCTCGAACGTCTGTGGTCCGACCTTCCCAGCGATGGGGCGGTTGCCGAGGAG
GCGCTGGGCGGGGTGCGTGG

Downstream 100 bases:

>100_bases
GCATCCAGGCCATGACGTGCCGGGGTGAATGCCTTCCACCTTCCCGCTTGTTATCGGGGACCCATGCGTAAACGTCGCGA
CGCAATCAAGGATACCGAAC

Product: hypothetical protein

Products: NA

Alternate protein names: 23S rRNA m3Psi1915 methyltransferase; rRNA (pseudouridine-N3-)-methyltransferase rlmH

Number of amino acids: Translated: 155; Mature: 155

Protein sequence:

>155_residues
MKLRVLAVGTRMPDWVTRGVDEYLKRLPRDFSVEIVEIAPGKRGKNADVARAIQGEGNAMLAKLRDQERVIALAVDGQHW
STERLAANADHWRQDGRDVALLVGGPDGLDPRLLSRVEQRWSLSALTLPHPLVRILLAEQLYRAWTLLAGHPYHR

Sequences:

>Translated_155_residues
MKLRVLAVGTRMPDWVTRGVDEYLKRLPRDFSVEIVEIAPGKRGKNADVARAIQGEGNAMLAKLRDQERVIALAVDGQHW
STERLAANADHWRQDGRDVALLVGGPDGLDPRLLSRVEQRWSLSALTLPHPLVRILLAEQLYRAWTLLAGHPYHR
>Mature_155_residues
MKLRVLAVGTRMPDWVTRGVDEYLKRLPRDFSVEIVEIAPGKRGKNADVARAIQGEGNAMLAKLRDQERVIALAVDGQHW
STERLAANADHWRQDGRDVALLVGGPDGLDPRLLSRVEQRWSLSALTLPHPLVRILLAEQLYRAWTLLAGHPYHR

Specific function: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA

COG id: COG1576

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase rlmH family

Homologues:

Organism=Escherichia coli, GI1786855, Length=155, Percent_Identity=56.1290322580645, Blast_Score=189, Evalue=6e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RLMH_CHRSD (Q1QXB1)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_573596.1
- ProteinModelPortal:   Q1QXB1
- SMR:   Q1QXB1
- STRING:   Q1QXB1
- GeneID:   4027642
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_1544
- NMPDR:   fig|290398.4.peg.2599
- eggNOG:   COG1576
- HOGENOM:   HBG622807
- OMA:   TANHPYH
- BioCyc:   CSAL290398:CSAL_1544-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00658
- InterPro:   IPR016051
- InterPro:   IPR003742
- PIRSF:   PIRSF004505
- TIGRFAMs:   TIGR00246

Pfam domain/function: PF02590 SPOUT_MTase

EC number: NA

Molecular weight: Translated: 17482; Mature: 17482

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRVLAVGTRMPDWVTRGVDEYLKRLPRDFSVEIVEIAPGKRGKNADVARAIQGEGNAM
CEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCEE
LAKLRDQERVIALAVDGQHWSTERLAANADHWRQDGRDVALLVGGPDGLDPRLLSRVEQR
EEEECCCCEEEEEEECCCCCCHHHHHCCCHHHHCCCCEEEEEEECCCCCCHHHHHHHHHH
WSLSALTLPHPLVRILLAEQLYRAWTLLAGHPYHR
HCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKLRVLAVGTRMPDWVTRGVDEYLKRLPRDFSVEIVEIAPGKRGKNADVARAIQGEGNAM
CEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHCCCCCEE
LAKLRDQERVIALAVDGQHWSTERLAANADHWRQDGRDVALLVGGPDGLDPRLLSRVEQR
EEEECCCCEEEEEEECCCCCCHHHHHCCCHHHHCCCCEEEEEEECCCCCCHHHHHHHHHH
WSLSALTLPHPLVRILLAEQLYRAWTLLAGHPYHR
HCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA