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The map label for this gene is qor [H]

Identifier: 92113632

GI number: 92113632

Start: 1710056

End: 1711033

Strand: Direct

Name: qor [H]

Synonym: Csal_1508

Alternate gene names: 92113632

Gene position: 1710056-1711033 (Clockwise)

Preceding gene: 92113631

Following gene: 92113633

Centisome position: 46.26

GC content: 65.75

Gene sequence:

>978_bases
ATGGCCAAGCGTATCCAATTCGCACGCACCGGTGGCCCCGAGGTACTGGAGTACGTCGACGTGACGCCCGCCGAACCCGG
CCCGGGCGAGGTTCGCGTTCGCAATCACGCGGTGGGGCTGAATTTCATCGACATCTATTTCCGTACCGGCCTCTACCCGG
CGCCCAGCTTGCCTTCCGGGCTGGGCACCGAAGGGGCCGGTGAGATCGACGCCGTGGGCGAGGGTGTCACCATGTTCGCG
CCGGGCGATCGCGTCGCCTACGCCCAGGGCCCGCTCGGCGCCTATGCCGAGCAGCATGTATTGCCGGCGGAAAAGGTCGT
CGCCTTGCCCGACGCCATCGATTACGAGACGGCCGCTGCCGCCATGCTCAAGGGGCTGACGGTGCAGTACCTGCTGCGCC
AGACGTATCGGGTCAAGGAAGGCGAGACGATCCTCTTTCATGCGGCGGCGGGCGGCGTCGGCTCGATCGCCTGCCAATGG
GCCAAGGCACTCGGCGTCAAGCTGATCGGCACCGTCGGGTCGCCGGAAAAGGCTGAGCTGGCCAAGCGCAATGGCGCCTG
GGCCACCATCGACTATACCCGCGAGAACGTCGTCGAGCGCGTTCGCGAGCTGACCGGCGGTGAAATGGTGCCGGTGGTCT
ACGATTCGGTGGGCAAGGACACCTGGGAAACCTCGCTGGACTGTCTCCAGAAACGCGGCCTGATGGTGAGCTTCGGCAAT
GCGTCCGGTCCGGTCGAGGGCGTCAACATCGGCATCCTCAATCAGAAGGGCGCCTTGTTCGTGACGCGCCCCAGCCTCAA
CGGTTACGCCGACACGCGTGAACGTTTCGAGGCCATGGCCGCGGAACTCTTCGAGGTGATCGCCAGCGGCCAGGTCACCA
TCGATGTCGCCAACCGCTATCCGCTGCGCGATGCGGCCAAGGCACAGGAAGCGCTAGCGGGGCGTCAGACGACCGGCTCG
ACGGTATTGCTACCCTGA

Upstream 100 bases:

>100_bases
CGGTCCATTGGGCGAAGGTCGTCGTCTGGATGACTTGACCCGGCGCACGTTCGGCGCTTGGATGAAGGCCTGAACCCGTT
AGCTTCATAAGGAATCATGC

Downstream 100 bases:

>100_bases
TGTGGCGTCGTATATCTCGGCTGATGGCGGTCGTGAGCGGGACGGTTGCCGTGGTGGCGTTGGCGGGATGCGCCACCGAT
GGTGACGCAACGTCCGCCGG

Product: zinc-binding alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MAKRIQFARTGGPEVLEYVDVTPAEPGPGEVRVRNHAVGLNFIDIYFRTGLYPAPSLPSGLGTEGAGEIDAVGEGVTMFA
PGDRVAYAQGPLGAYAEQHVLPAEKVVALPDAIDYETAAAAMLKGLTVQYLLRQTYRVKEGETILFHAAAGGVGSIACQW
AKALGVKLIGTVGSPEKAELAKRNGAWATIDYTRENVVERVRELTGGEMVPVVYDSVGKDTWETSLDCLQKRGLMVSFGN
ASGPVEGVNIGILNQKGALFVTRPSLNGYADTRERFEAMAAELFEVIASGQVTIDVANRYPLRDAAKAQEALAGRQTTGS
TVLLP

Sequences:

>Translated_325_residues
MAKRIQFARTGGPEVLEYVDVTPAEPGPGEVRVRNHAVGLNFIDIYFRTGLYPAPSLPSGLGTEGAGEIDAVGEGVTMFA
PGDRVAYAQGPLGAYAEQHVLPAEKVVALPDAIDYETAAAAMLKGLTVQYLLRQTYRVKEGETILFHAAAGGVGSIACQW
AKALGVKLIGTVGSPEKAELAKRNGAWATIDYTRENVVERVRELTGGEMVPVVYDSVGKDTWETSLDCLQKRGLMVSFGN
ASGPVEGVNIGILNQKGALFVTRPSLNGYADTRERFEAMAAELFEVIASGQVTIDVANRYPLRDAAKAQEALAGRQTTGS
TVLLP
>Mature_324_residues
AKRIQFARTGGPEVLEYVDVTPAEPGPGEVRVRNHAVGLNFIDIYFRTGLYPAPSLPSGLGTEGAGEIDAVGEGVTMFAP
GDRVAYAQGPLGAYAEQHVLPAEKVVALPDAIDYETAAAAMLKGLTVQYLLRQTYRVKEGETILFHAAAGGVGSIACQWA
KALGVKLIGTVGSPEKAELAKRNGAWATIDYTRENVVERVRELTGGEMVPVVYDSVGKDTWETSLDCLQKRGLMVSFGNA
SGPVEGVNIGILNQKGALFVTRPSLNGYADTRERFEAMAAELFEVIASGQVTIDVANRYPLRDAAKAQEALAGRQTTGST
VLLP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=330, Percent_Identity=29.6969696969697, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI13236495, Length=330, Percent_Identity=29.6969696969697, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI194239676, Length=328, Percent_Identity=29.5731707317073, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI22538446, Length=330, Percent_Identity=28.1818181818182, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI22538444, Length=330, Percent_Identity=28.1818181818182, Blast_Score=112, Evalue=4e-25,
Organism=Homo sapiens, GI18379349, Length=313, Percent_Identity=29.073482428115, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI28557745, Length=281, Percent_Identity=32.0284697508897, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI24308257, Length=249, Percent_Identity=29.718875502008, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI197927207, Length=191, Percent_Identity=28.2722513089005, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI67078404, Length=318, Percent_Identity=25.7861635220126, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI67078406, Length=287, Percent_Identity=25.7839721254355, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI47519420, Length=247, Percent_Identity=28.7449392712551, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI41872631, Length=224, Percent_Identity=29.9107142857143, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=61.7737003058104, Blast_Score=419, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17507255, Length=234, Percent_Identity=30.7692307692308, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17536829, Length=311, Percent_Identity=27.0096463022508, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17556000, Length=168, Percent_Identity=32.7380952380952, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=325, Percent_Identity=36.3076923076923, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6323961, Length=313, Percent_Identity=26.1980830670927, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324486, Length=300, Percent_Identity=26, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319621, Length=313, Percent_Identity=26.8370607028754, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=304, Percent_Identity=25.9868421052632, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45550423, Length=311, Percent_Identity=25.08038585209, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34571; Mature: 34440

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKRIQFARTGGPEVLEYVDVTPAEPGPGEVRVRNHAVGLNFIDIYFRTGLYPAPSLPSG
CCCCEEEECCCCHHHHHEEECCCCCCCCCCEEEEEEEECCEEEEEEECCCCCCCCCCCCC
LGTEGAGEIDAVGEGVTMFAPGDRVAYAQGPLGAYAEQHVLPAEKVVALPDAIDYETAAA
CCCCCCCCCHHCCCCEEEECCCCEEEEECCCCCHHHHHCCCCHHHEEECCCCCCHHHHHH
AMLKGLTVQYLLRQTYRVKEGETILFHAAAGGVGSIACQWAKALGVKLIGTVGSPEKAEL
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCEEEEECCCCCHHHHH
AKRNGAWATIDYTRENVVERVRELTGGEMVPVVYDSVGKDTWETSLDCLQKRGLMVSFGN
HHCCCCEEEEECHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEECC
ASGPVEGVNIGILNQKGALFVTRPSLNGYADTRERFEAMAAELFEVIASGQVTIDVANRY
CCCCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
PLRDAAKAQEALAGRQTTGSTVLLP
CCHHHHHHHHHHCCCCCCCCEEECC
>Mature Secondary Structure 
AKRIQFARTGGPEVLEYVDVTPAEPGPGEVRVRNHAVGLNFIDIYFRTGLYPAPSLPSG
CCCEEEECCCCHHHHHEEECCCCCCCCCCEEEEEEEECCEEEEEEECCCCCCCCCCCCC
LGTEGAGEIDAVGEGVTMFAPGDRVAYAQGPLGAYAEQHVLPAEKVVALPDAIDYETAAA
CCCCCCCCCHHCCCCEEEECCCCEEEEECCCCCHHHHHCCCCHHHEEECCCCCCHHHHHH
AMLKGLTVQYLLRQTYRVKEGETILFHAAAGGVGSIACQWAKALGVKLIGTVGSPEKAEL
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHCCEEEEECCCCCHHHHH
AKRNGAWATIDYTRENVVERVRELTGGEMVPVVYDSVGKDTWETSLDCLQKRGLMVSFGN
HHCCCCEEEEECHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHCCCEEEECC
ASGPVEGVNIGILNQKGALFVTRPSLNGYADTRERFEAMAAELFEVIASGQVTIDVANRY
CCCCCCCEEEEEEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
PLRDAAKAQEALAGRQTTGSTVLLP
CCHHHHHHHHHHCCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]