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The map label for this gene is yccK [H]

Identifier: 92113562

GI number: 92113562

Start: 1627090

End: 1628091

Strand: Direct

Name: yccK [H]

Synonym: Csal_1438

Alternate gene names: 92113562

Gene position: 1627090-1628091 (Clockwise)

Preceding gene: 92113561

Following gene: 92113565

Centisome position: 44.02

GC content: 65.87

Gene sequence:

>1002_bases
ATGCCGAACATGTTGTCTTTGCTCGAGGAAGTCGCGTCACCGACCATCGGGCTCGGTTGCATGAACCTGTCCCATGGTTA
CGGGGCGCCGGTGCCGGAAGCCGAAGGCGTACGAGCGTTGCAGGCGGCGTTCGAGATGGGCTATCGGCATTTCGACACCG
CGACCCTCTATGGCGCGACCGCCAACGAGTCGCTGGTGGGCAAGGCGCTCGAGGGACGACGCGATCAGTTGCTGCTGGCC
AGCAAATGCGGCATGGCGATCGACCCGGCGCTCGGCCGCAAGGTGATCGACGGTCGCCCCGAGACGCTGCGTCGCCAGTG
CGAGGCGAGCCTGCAGCGTCTGCGGACCGATCGACTGGATCTCTATTACCTGCATCGCATGGACCGCCAGGTCCCCATCG
AGGAGAGCGTCGGGGCACTGGGGCGGCTGGTCGAGGAGGGCAAGCTGCGTGCCGTGGGGTTGTCCGAGGTCTCCGCCGAG
ACGCTGCGTCGTGCCCATGCCGAGTATCCGGTGGCGGCGGTACAGTCGGAATACTCACTGTGGACGCGCAATCCTGAGAT
CGCCTTGCTTGCGGCATGCCGTGAACTGAGCACTACGCTGGTGGCATTCAGCCCGCTGGGCCGAGGCTTTCTCGCGGATG
CAGTCCCGGATCCGGCGCGTCTGGAAGAAAGCGACATGCGACGCGGTATGCCGCGTTTCAGTGCCGAGCATTACCCGCAT
AACCAGCGCTTGCTGACGGATTTCACCGCGCTCGCTGAGGCGCTGTCGATGACGCCGGGGCAATTGGCGCTGGCGTGGGT
GACGGCGCAGGGGGCCGATATCGTGCCCATTCCCGGCACGCGCGACATCGCGCACATGCGTGAGAACCTGGCGGCGGAAA
CGCGGTATCTGGACGACGCGTCGCTCGCCCGGCTGAACGCGATGATGACCCCCGATCAGGTCAGGGGCGGGCGCTACAGC
GAAGCCCAGCAGGCGGACATCGATACCGAGGAGTTCGCCTGA

Upstream 100 bases:

>100_bases
GATGACAGCGCACCCCGGGAAGGTGTTCTCTTGCTAAGCTGGGGCTCTGTCATCCCGGTCGTCGACCGGTCGTGTTCTTT
TTGCGTACAAGGATTTCTCC

Downstream 100 bases:

>100_bases
CGACCATCCTGTGCGCGCCGCGTTTCACGCACAGTGCGTGTCGGTGATCTCTGACAGGCAAATGACCGAGCAGGCTCTAG
GATGAAAGTGCGGCGAGGGA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MPNMLSLLEEVASPTIGLGCMNLSHGYGAPVPEAEGVRALQAAFEMGYRHFDTATLYGATANESLVGKALEGRRDQLLLA
SKCGMAIDPALGRKVIDGRPETLRRQCEASLQRLRTDRLDLYYLHRMDRQVPIEESVGALGRLVEEGKLRAVGLSEVSAE
TLRRAHAEYPVAAVQSEYSLWTRNPEIALLAACRELSTTLVAFSPLGRGFLADAVPDPARLEESDMRRGMPRFSAEHYPH
NQRLLTDFTALAEALSMTPGQLALAWVTAQGADIVPIPGTRDIAHMRENLAAETRYLDDASLARLNAMMTPDQVRGGRYS
EAQQADIDTEEFA

Sequences:

>Translated_333_residues
MPNMLSLLEEVASPTIGLGCMNLSHGYGAPVPEAEGVRALQAAFEMGYRHFDTATLYGATANESLVGKALEGRRDQLLLA
SKCGMAIDPALGRKVIDGRPETLRRQCEASLQRLRTDRLDLYYLHRMDRQVPIEESVGALGRLVEEGKLRAVGLSEVSAE
TLRRAHAEYPVAAVQSEYSLWTRNPEIALLAACRELSTTLVAFSPLGRGFLADAVPDPARLEESDMRRGMPRFSAEHYPH
NQRLLTDFTALAEALSMTPGQLALAWVTAQGADIVPIPGTRDIAHMRENLAAETRYLDDASLARLNAMMTPDQVRGGRYS
EAQQADIDTEEFA
>Mature_332_residues
PNMLSLLEEVASPTIGLGCMNLSHGYGAPVPEAEGVRALQAAFEMGYRHFDTATLYGATANESLVGKALEGRRDQLLLAS
KCGMAIDPALGRKVIDGRPETLRRQCEASLQRLRTDRLDLYYLHRMDRQVPIEESVGALGRLVEEGKLRAVGLSEVSAET
LRRAHAEYPVAAVQSEYSLWTRNPEIALLAACRELSTTLVAFSPLGRGFLADAVPDPARLEESDMRRGMPRFSAEHYPHN
QRLLTDFTALAEALSMTPGQLALAWVTAQGADIVPIPGTRDIAHMRENLAAETRYLDDASLARLNAMMTPDQVRGGRYSE
AQQADIDTEEFA

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI223718702, Length=237, Percent_Identity=29.535864978903, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI41152114, Length=232, Percent_Identity=30.1724137931034, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI27436966, Length=285, Percent_Identity=27.0175438596491, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI27436964, Length=285, Percent_Identity=27.0175438596491, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI27436962, Length=296, Percent_Identity=26.6891891891892, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI41327764, Length=206, Percent_Identity=27.6699029126214, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI27436969, Length=296, Percent_Identity=24.3243243243243, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI4504825, Length=309, Percent_Identity=23.6245954692557, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI223718708, Length=148, Percent_Identity=33.1081081081081, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI27436971, Length=260, Percent_Identity=26.5384615384615, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1788070, Length=312, Percent_Identity=29.8076923076923, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87081735, Length=315, Percent_Identity=28.8888888888889, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788081, Length=310, Percent_Identity=30.6451612903226, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1787674, Length=307, Percent_Identity=27.6872964169381, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI1789375, Length=298, Percent_Identity=28.5234899328859, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1789199, Length=342, Percent_Identity=27.1929824561404, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786400, Length=297, Percent_Identity=25.5892255892256, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI48994888, Length=273, Percent_Identity=24.9084249084249, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17566692, Length=330, Percent_Identity=26.3636363636364, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17564128, Length=325, Percent_Identity=25.2307692307692, Blast_Score=75, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6325384, Length=340, Percent_Identity=26.4705882352941, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6323998, Length=305, Percent_Identity=22.9508196721311, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6319958, Length=296, Percent_Identity=22.972972972973, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6325169, Length=326, Percent_Identity=23.6196319018405, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322615, Length=256, Percent_Identity=22.265625, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI45553081, Length=324, Percent_Identity=25.9259259259259, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281366140, Length=292, Percent_Identity=25.6849315068493, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24657054, Length=323, Percent_Identity=23.8390092879257, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36537; Mature: 36406

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNMLSLLEEVASPTIGLGCMNLSHGYGAPVPEAEGVRALQAAFEMGYRHFDTATLYGAT
CCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCHHHCCCCEEECCC
ANESLVGKALEGRRDQLLLASKCGMAIDPALGRKVIDGRPETLRRQCEASLQRLRTDRLD
CCHHHHHHHHCCCCHHEEHHHHCCCEECHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHH
LYYLHRMDRQVPIEESVGALGRLVEEGKLRAVGLSEVSAETLRRAHAEYPVAAVQSEYSL
HHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHH
WTRNPEIALLAACRELSTTLVAFSPLGRGFLADAVPDPARLEESDMRRGMPRFSAEHYPH
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHCCHHHHHCCCCCCCCCCCCC
NQRLLTDFTALAEALSMTPGQLALAWVTAQGADIVPIPGTRDIAHMRENLAAETRYLDDA
CCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHCCCH
SLARLNAMMTPDQVRGGRYSEAQQADIDTEEFA
HHHHHHHHCCCHHHCCCCCCCHHHCCCCHHHCC
>Mature Secondary Structure 
PNMLSLLEEVASPTIGLGCMNLSHGYGAPVPEAEGVRALQAAFEMGYRHFDTATLYGAT
CHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCHHHCCCCEEECCC
ANESLVGKALEGRRDQLLLASKCGMAIDPALGRKVIDGRPETLRRQCEASLQRLRTDRLD
CCHHHHHHHHCCCCHHEEHHHHCCCEECHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHHH
LYYLHRMDRQVPIEESVGALGRLVEEGKLRAVGLSEVSAETLRRAHAEYPVAAVQSEYSL
HHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHH
WTRNPEIALLAACRELSTTLVAFSPLGRGFLADAVPDPARLEESDMRRGMPRFSAEHYPH
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHCCHHHHHCCCCCCCCCCCCC
NQRLLTDFTALAEALSMTPGQLALAWVTAQGADIVPIPGTRDIAHMRENLAAETRYLDDA
CCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEECCCCHHHHHHHHHHHHHHHHCCCH
SLARLNAMMTPDQVRGGRYSEAQQADIDTEEFA
HHHHHHHHCCCHHHCCCCCCCHHHCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]