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The map label for this gene is hflC [H]

Identifier: 92113406

GI number: 92113406

Start: 1460463

End: 1461356

Strand: Direct

Name: hflC [H]

Synonym: Csal_1280

Alternate gene names: 92113406

Gene position: 1460463-1461356 (Clockwise)

Preceding gene: 92113405

Following gene: 92113407

Centisome position: 39.51

GC content: 61.19

Gene sequence:

>894_bases
ATGGTCAACAATCGTGCCTTAGGTATCGTCGCACTGCTGGCCGTGGGGGCCTGGCTCGCAAGTGCCAGCCTGTATGTGGT
GACGGAAACGCAGCGGGCCATCAAGCTGCGCTTCGGTGAAGTCGTCGAATCCGACATCCAGCCCGGCCTGCATTTCAAGT
GGCCGGTTCTCAACACCGTGCGTTATTTCGATGCACGCGTGCAGACGCTGGAAAGCACCGAAAGCCGCTTTTTGACGGCG
CGTCGCAACGCCTTGATCGTCGATTCCTACGTCAAATGGCAGGTCGTCGACCCGAGCCTGTTCTATCAGGCGACACGCGG
TGATCCGGCGCGCGCCGAGAACCTCATCGCGCCACGCGTCGACGAGAGTCTGCGCAACGCATTCGGCAGTCGCGAGGTGA
ACAAGATCATCAGCGAAGACCGCAATGAAATGTTGCAGAAGCCCCAGCAGACGCTGGACGAGGAATTGCGCGACGAAGTC
GGGGTGGCGATCCTGGATATTCGCCTCAAGCGTGTCGAGCTGCCGCAGGAAGTTCGTCAGGCGGTTTTCGAGCGCATGCG
CACCGAGCGCTACGCCGAGGCACGCCAGTACCGTGCGCAAGGGCAGGAACAGGCCGAGCGCATTCGTGCGCGGGCCGATC
GCGAGCGCCAGGTGAAACTGGCCGAGGCACGCGAGAAGGCGGAGACACTGCGCGGTCAAGGCGATGCCGAGGCTGCCCAT
ATCTACGCCAACGCGTATCAGCAGGATGAAGATTTCTTCAACTTCTATCGCTCACTCGAAGCCTACCGCAACAGCTTCGA
CAAGGGTGACGACATGCTGCTGCTGAGCCCGGACAGCGAATTCTTCCGCTACTTCCGCTCGGCTGACGGCAACGACGACG
CAAGCCAGCCATAG

Upstream 100 bases:

>100_bases
AATCGATCTCCCAGCAGGTGCAGAACGAGCCGCTTTCCGGTAGCGACAACACGAGCAGTCAGCGCCAGTCGGGCGGCATT
TCGCGGGAGGGTCGTTAATC

Downstream 100 bases:

>100_bases
TGGCACTCGGGCCCCCGGGGTACACCCGGGGGCCAAACGTGATAGACTCTTGACACCGGGCGAGGCCCGGTTTTTTTGTG
GCCTGTCCGCGGCCTGAGCG

Product: HflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MVNNRALGIVALLAVGAWLASASLYVVTETQRAIKLRFGEVVESDIQPGLHFKWPVLNTVRYFDARVQTLESTESRFLTA
RRNALIVDSYVKWQVVDPSLFYQATRGDPARAENLIAPRVDESLRNAFGSREVNKIISEDRNEMLQKPQQTLDEELRDEV
GVAILDIRLKRVELPQEVRQAVFERMRTERYAEARQYRAQGQEQAERIRARADRERQVKLAEAREKAETLRGQGDAEAAH
IYANAYQQDEDFFNFYRSLEAYRNSFDKGDDMLLLSPDSEFFRYFRSADGNDDASQP

Sequences:

>Translated_297_residues
MVNNRALGIVALLAVGAWLASASLYVVTETQRAIKLRFGEVVESDIQPGLHFKWPVLNTVRYFDARVQTLESTESRFLTA
RRNALIVDSYVKWQVVDPSLFYQATRGDPARAENLIAPRVDESLRNAFGSREVNKIISEDRNEMLQKPQQTLDEELRDEV
GVAILDIRLKRVELPQEVRQAVFERMRTERYAEARQYRAQGQEQAERIRARADRERQVKLAEAREKAETLRGQGDAEAAH
IYANAYQQDEDFFNFYRSLEAYRNSFDKGDDMLLLSPDSEFFRYFRSADGNDDASQP
>Mature_297_residues
MVNNRALGIVALLAVGAWLASASLYVVTETQRAIKLRFGEVVESDIQPGLHFKWPVLNTVRYFDARVQTLESTESRFLTA
RRNALIVDSYVKWQVVDPSLFYQATRGDPARAENLIAPRVDESLRNAFGSREVNKIISEDRNEMLQKPQQTLDEELRDEV
GVAILDIRLKRVELPQEVRQAVFERMRTERYAEARQYRAQGQEQAERIRARADRERQVKLAEAREKAETLRGQGDAEAAH
IYANAYQQDEDFFNFYRSLEAYRNSFDKGDDMLLLSPDSEFFRYFRSADGNDDASQP

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=310, Percent_Identity=39.0322580645161, Blast_Score=225, Evalue=2e-60,
Organism=Escherichia coli, GI1790616, Length=218, Percent_Identity=26.1467889908257, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 34279; Mature: 34279

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNNRALGIVALLAVGAWLASASLYVVTETQRAIKLRFGEVVESDIQPGLHFKWPVLNTV
CCCCHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHCCCCCEEECHHHHHH
RYFDARVQTLESTESRFLTARRNALIVDSYVKWQVVDPSLFYQATRGDPARAENLIAPRV
HHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEEECHHHHHEECCCCHHHHHCCCCCHH
DESLRNAFGSREVNKIISEDRNEMLQKPQQTLDEELRDEVGVAILDIRLKRVELPQEVRQ
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHCCCHHHHH
AVFERMRTERYAEARQYRAQGQEQAERIRARADRERQVKLAEAREKAETLRGQGDAEAAH
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHH
IYANAYQQDEDFFNFYRSLEAYRNSFDKGDDMLLLSPDSEFFRYFRSADGNDDASQP
HHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MVNNRALGIVALLAVGAWLASASLYVVTETQRAIKLRFGEVVESDIQPGLHFKWPVLNTV
CCCCHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHCCCCCEEECHHHHHH
RYFDARVQTLESTESRFLTARRNALIVDSYVKWQVVDPSLFYQATRGDPARAENLIAPRV
HHHHHHHHHHHHHHHHHHHHHCCEEEEECCEEEEEECHHHHHEECCCCHHHHHCCCCCHH
DESLRNAFGSREVNKIISEDRNEMLQKPQQTLDEELRDEVGVAILDIRLKRVELPQEVRQ
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHCCCHHHHH
AVFERMRTERYAEARQYRAQGQEQAERIRARADRERQVKLAEAREKAETLRGQGDAEAAH
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHH
IYANAYQQDEDFFNFYRSLEAYRNSFDKGDDMLLLSPDSEFFRYFRSADGNDDASQP
HHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]