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The map label for this gene is yeiG [H]

Identifier: 92113114

GI number: 92113114

Start: 1106285

End: 1107142

Strand: Direct

Name: yeiG [H]

Synonym: Csal_0986

Alternate gene names: 92113114

Gene position: 1106285-1107142 (Clockwise)

Preceding gene: 92113113

Following gene: 92113115

Centisome position: 29.93

GC content: 62.94

Gene sequence:

>858_bases
ATGACCATGTCCGAATCGCTGGAGCTGGTCTCCGCCACCAAGTCGTTCGGCGGCTGGCTGAAGCGCTACAAGCATCACTC
GCGTGCACTCGACTGCGAGATGATCTTCTCCATCTACCTGCCGCCTCAGGCGGAGACCGACAAGGTGCCGCTGTTGTGGT
GGTTGTCGGGGTTGACCTGCAACGACGAAAATTTCATGCAGAAGGCGGGGGCGCAGCGCGTGGCCGCCGAGCTGGGCATG
GCCATCGTCTGCCCGGATACCAGTCCGCGCGGTACCGAGCTTCCCGGCGAGCATGACAGCTATGACTTCGGCTCCGGCGC
GGGCTTCTACGTCAATGCCACCCAGGCGCCGTGGTCCAAGCATTACCGCATGTACGACTACGTCACCGAGGAACTGCCGT
CGGTGGTGCGCCAGCATTTTCCGCTCAATGGGCGTGAAGCGATCAGCGGCCACTCCATGGGCGGTCATGGCGCGCTGGTG
CTGGCCTTGCGCCAGCCCGGTCGCTACACCTCGGTGTCGGCGTTCGCGCCGGTGGTCAACCCGATCGTCTCGCCCTGGGG
GCAGAAGGCCTTCACGGCCTATCTCGGCGAGGATCATGGCAAGTGGACGCAATACGACGCCTGCGAACTGATCGCCAAGG
GGGCCTCGCGTCAGCCGCTGTTCATCGACCAGGGCGAAGCGGACAACTTTCTCGAGGAGCAGCTCATGCCCGAGCGCATC
GAAGCCACCTGCGAGAAACACGATCATCCGCTGACGCTGCGGCGTCAGCCGGGCTACGATCATAGCTATTTCTTCATCGC
GACCTTCATCGAAGAGCATTTGCGCTATCACGCCGAGTATCTGCACCGCAAGCGCTGA

Upstream 100 bases:

>100_bases
GCTTGACACGCGCCTGTGGTGATTCATCGCGTCCGGACGCCTCGCGACGTCGTTCCATCCGCCGGCGGCATGATGCCGCC
GGTTTCTCAGGGAGAGCATC

Downstream 100 bases:

>100_bases
GCGCGGACAGCCCGCTCCGGATATCGCCCCGCTCGATGCGGGGCGATTTCGTCGACGCGTACGGGGATGTCGTTTTTGAT
AGCGTAAGGCGACGCTTTTA

Product: carboxylesterase

Products: NA

Alternate protein names: FGH [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MTMSESLELVSATKSFGGWLKRYKHHSRALDCEMIFSIYLPPQAETDKVPLLWWLSGLTCNDENFMQKAGAQRVAAELGM
AIVCPDTSPRGTELPGEHDSYDFGSGAGFYVNATQAPWSKHYRMYDYVTEELPSVVRQHFPLNGREAISGHSMGGHGALV
LALRQPGRYTSVSAFAPVVNPIVSPWGQKAFTAYLGEDHGKWTQYDACELIAKGASRQPLFIDQGEADNFLEEQLMPERI
EATCEKHDHPLTLRRQPGYDHSYFFIATFIEEHLRYHAEYLHRKR

Sequences:

>Translated_285_residues
MTMSESLELVSATKSFGGWLKRYKHHSRALDCEMIFSIYLPPQAETDKVPLLWWLSGLTCNDENFMQKAGAQRVAAELGM
AIVCPDTSPRGTELPGEHDSYDFGSGAGFYVNATQAPWSKHYRMYDYVTEELPSVVRQHFPLNGREAISGHSMGGHGALV
LALRQPGRYTSVSAFAPVVNPIVSPWGQKAFTAYLGEDHGKWTQYDACELIAKGASRQPLFIDQGEADNFLEEQLMPERI
EATCEKHDHPLTLRRQPGYDHSYFFIATFIEEHLRYHAEYLHRKR
>Mature_284_residues
TMSESLELVSATKSFGGWLKRYKHHSRALDCEMIFSIYLPPQAETDKVPLLWWLSGLTCNDENFMQKAGAQRVAAELGMA
IVCPDTSPRGTELPGEHDSYDFGSGAGFYVNATQAPWSKHYRMYDYVTEELPSVVRQHFPLNGREAISGHSMGGHGALVL
ALRQPGRYTSVSAFAPVVNPIVSPWGQKAFTAYLGEDHGKWTQYDACELIAKGASRQPLFIDQGEADNFLEEQLMPERIE
ATCEKHDHPLTLRRQPGYDHSYFFIATFIEEHLRYHAEYLHRKR

Specific function: Serine hydrolase involved in the detoxification of formaldehyde. Hydrolyzes S-formylglutathione to glutathione and formate [H]

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the esterase D family [H]

Homologues:

Organism=Homo sapiens, GI33413400, Length=280, Percent_Identity=53.2142857142857, Blast_Score=329, Evalue=2e-90,
Organism=Escherichia coli, GI1788477, Length=279, Percent_Identity=56.6308243727599, Blast_Score=338, Evalue=2e-94,
Organism=Escherichia coli, GI1786551, Length=278, Percent_Identity=51.7985611510791, Blast_Score=325, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI17510185, Length=279, Percent_Identity=48.3870967741936, Blast_Score=275, Evalue=2e-74,
Organism=Saccharomyces cerevisiae, GI6322393, Length=297, Percent_Identity=42.0875420875421, Blast_Score=226, Evalue=4e-60,
Organism=Drosophila melanogaster, GI45551932, Length=286, Percent_Identity=54.1958041958042, Blast_Score=310, Evalue=6e-85,
Organism=Drosophila melanogaster, GI24648347, Length=281, Percent_Identity=54.4483985765125, Blast_Score=307, Evalue=6e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801
- InterPro:   IPR014186 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: =3.1.2.12 [H]

Molecular weight: Translated: 32289; Mature: 32158

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMSESLELVSATKSFGGWLKRYKHHSRALDCEMIFSIYLPPQAETDKVPLLWWLSGLTC
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEECCCCC
NDENFMQKAGAQRVAAELGMAIVCPDTSPRGTELPGEHDSYDFGSGAGFYVNATQAPWSK
CCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHH
HYRMYDYVTEELPSVVRQHFPLNGREAISGHSMGGHGALVLALRQPGRYTSVSAFAPVVN
HHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHH
PIVSPWGQKAFTAYLGEDHGKWTQYDACELIAKGASRQPLFIDQGEADNFLEEQLMPERI
HHHCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHCHHHH
EATCEKHDHPLTLRRQPGYDHSYFFIATFIEEHLRYHAEYLHRKR
HHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TMSESLELVSATKSFGGWLKRYKHHSRALDCEMIFSIYLPPQAETDKVPLLWWLSGLTC
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEEECCCCC
NDENFMQKAGAQRVAAELGMAIVCPDTSPRGTELPGEHDSYDFGSGAGFYVNATQAPWSK
CCHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHH
HYRMYDYVTEELPSVVRQHFPLNGREAISGHSMGGHGALVLALRQPGRYTSVSAFAPVVN
HHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHH
PIVSPWGQKAFTAYLGEDHGKWTQYDACELIAKGASRQPLFIDQGEADNFLEEQLMPERI
HHHCCCCCHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHCHHHH
EATCEKHDHPLTLRRQPGYDHSYFFIATFIEEHLRYHAEYLHRKR
HHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA