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The map label for this gene is nadA [H]

Identifier: 92112980

GI number: 92112980

Start: 952345

End: 953373

Strand: Direct

Name: nadA [H]

Synonym: Csal_0852

Alternate gene names: 92112980

Gene position: 952345-953373 (Clockwise)

Preceding gene: 92112979

Following gene: 92112982

Centisome position: 25.76

GC content: 67.83

Gene sequence:

>1029_bases
ATGACGATCATGACACCGAAAGCGCCGGCCACAACGTCGCTGGCGCGTACCTATTGTCCCGCCGTGCCCAGTGCCCGGGC
GCGCGCCCAGGCCGAGACGATCCAGCGCTTGCTGCGCGAGCGCGATGCCGTGCTGGTGGCGCATTACTATACCGACGATG
CCATTCAACAGCTGGCCGAGGAAAGCGGCGGCTGCGTGGCCGACTCCCTGGAAATGGCCCGCTTCGGCGCACGGCACCCG
GCCACCACGCTGGTCGTGGCCGGCGTGCGTTTCATGGGCGAGACGGCCAAGATCCTTTCCCCCGAAAAGCGCGTGGTCAT
GCCCACGCTGGAGGCGACCTGCTCGCTCGACGAAGGATGCCCGCCGGCGGCGTTCGCGGCCTTCTGCGACGCACATCCCG
ATCGCACCGTGGTGGTCTATGCCAACACGTCGGCGGCGGTCAAGGCGCGTGCCGACTGGGTGGTGACCTCGTCGATCGCG
GTCGAGGTGATCGAGCACCTGCATGCCCGTGGTGAAAAGATCCTGTGGGCGCCGGACAAGCACCTGGGACGCTACATCCG
CGAGCGTACCGGTGCCGACATGCTGCTGTGGGACGGGGCCTGCATCGTGCACGAGGAGTTCAAGGCACAAGGGGTGCTGG
ATCTGAAGAAGGTCTACCCCCAGGCCGCCTTGCTGGTGCATCCCGAGTCGCCGTCGGCGGTGATTGAGCTGGCCGACGTG
GTGGGGTCGACCTCGCAGTTGATCCAGGCCGCGCGCGAGCTGGAGCAGCCTCAACTGATCGTGGCCACCGACCGCGGCAT
TTTCTACAAGATGCAGCAGGCGGTGCCCGAGAAGACGCTCATCGAGGCACCGACCGCGGGCGAGGGTGCGACCTGCCGCA
GCTGCGCGCACTGCCCGTGGATGGCGATGAACGACCTCGACCGTCTCGAGCACGCGCTGCGCGAGGGCGGCGGCGACATC
GAGGTCGAAGCGGGCCTGCGCGAACGTGCCCTCGCGCCGCTGGAGCGGATGCTCGCCTTCGGACGTTGA

Upstream 100 bases:

>100_bases
GGCCGTATCATGATGGCGGGTGTGGCGTGTCGCGAAGAGATCGCAAGCGCCGCTTCTCGTTACGCAGGGGGAGCCCCTGC
CAGTCGCAGTGGTAGACACG

Downstream 100 bases:

>100_bases
GCCGCGTCGCCAGGGGCGATCAGCGTGTCTCGGTGCGTACCACGCGCATCGAGAGATCGATGGCCTTGACGTCCTTGGTC
AGCGCGCCGATGGAGATGCA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MTIMTPKAPATTSLARTYCPAVPSARARAQAETIQRLLRERDAVLVAHYYTDDAIQQLAEESGGCVADSLEMARFGARHP
ATTLVVAGVRFMGETAKILSPEKRVVMPTLEATCSLDEGCPPAAFAAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIA
VEVIEHLHARGEKILWAPDKHLGRYIRERTGADMLLWDGACIVHEEFKAQGVLDLKKVYPQAALLVHPESPSAVIELADV
VGSTSQLIQAARELEQPQLIVATDRGIFYKMQQAVPEKTLIEAPTAGEGATCRSCAHCPWMAMNDLDRLEHALREGGGDI
EVEAGLRERALAPLERMLAFGR

Sequences:

>Translated_342_residues
MTIMTPKAPATTSLARTYCPAVPSARARAQAETIQRLLRERDAVLVAHYYTDDAIQQLAEESGGCVADSLEMARFGARHP
ATTLVVAGVRFMGETAKILSPEKRVVMPTLEATCSLDEGCPPAAFAAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIA
VEVIEHLHARGEKILWAPDKHLGRYIRERTGADMLLWDGACIVHEEFKAQGVLDLKKVYPQAALLVHPESPSAVIELADV
VGSTSQLIQAARELEQPQLIVATDRGIFYKMQQAVPEKTLIEAPTAGEGATCRSCAHCPWMAMNDLDRLEHALREGGGDI
EVEAGLRERALAPLERMLAFGR
>Mature_341_residues
TIMTPKAPATTSLARTYCPAVPSARARAQAETIQRLLRERDAVLVAHYYTDDAIQQLAEESGGCVADSLEMARFGARHPA
TTLVVAGVRFMGETAKILSPEKRVVMPTLEATCSLDEGCPPAAFAAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
EVIEHLHARGEKILWAPDKHLGRYIRERTGADMLLWDGACIVHEEFKAQGVLDLKKVYPQAALLVHPESPSAVIELADVV
GSTSQLIQAARELEQPQLIVATDRGIFYKMQQAVPEKTLIEAPTAGEGATCRSCAHCPWMAMNDLDRLEHALREGGGDIE
VEAGLRERALAPLERMLAFGR

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=311, Percent_Identity=72.6688102893891, Blast_Score=478, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 37177; Mature: 37046

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIMTPKAPATTSLARTYCPAVPSARARAQAETIQRLLRERDAVLVAHYYTDDAIQQLAE
CCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHH
ESGGCVADSLEMARFGARHPATTLVVAGVRFMGETAKILSPEKRVVMPTLEATCSLDEGC
HCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHCCCCCEEEEECHHHHCCCCCCC
PPAAFAAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVEVIEHLHARGEKILWAPDK
CHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHHHCCCEEEECCCH
HLGRYIRERTGADMLLWDGACIVHEEFKAQGVLDLKKVYPQAALLVHPESPSAVIELADV
HHHHHHHHHCCCCEEEECCEEEEEHHHHCCCCHHHHHHCCCEEEEEECCCCHHHHHHHHH
VGSTSQLIQAARELEQPQLIVATDRGIFYKMQQAVPEKTLIEAPTAGEGATCRSCAHCPW
HCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCHHHEECCCCCCCCCCCHHHCCCCC
MAMNDLDRLEHALREGGGDIEVEAGLRERALAPLERMLAFGR
HHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIMTPKAPATTSLARTYCPAVPSARARAQAETIQRLLRERDAVLVAHYYTDDAIQQLAE
CCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHH
ESGGCVADSLEMARFGARHPATTLVVAGVRFMGETAKILSPEKRVVMPTLEATCSLDEGC
HCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHCCCCCEEEEECHHHHCCCCCCC
PPAAFAAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVEVIEHLHARGEKILWAPDK
CHHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHHHCCCEEEECCCH
HLGRYIRERTGADMLLWDGACIVHEEFKAQGVLDLKKVYPQAALLVHPESPSAVIELADV
HHHHHHHHHCCCCEEEECCEEEEEHHHHCCCCHHHHHHCCCEEEEEECCCCHHHHHHHHH
VGSTSQLIQAARELEQPQLIVATDRGIFYKMQQAVPEKTLIEAPTAGEGATCRSCAHCPW
HCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCHHHEECCCCCCCCCCCHHHCCCCC
MAMNDLDRLEHALREGGGDIEVEAGLRERALAPLERMLAFGR
HHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA