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The map label for this gene is tadA [H]

Identifier: 92112967

GI number: 92112967

Start: 936999

End: 937454

Strand: Direct

Name: tadA [H]

Synonym: Csal_0839

Alternate gene names: 92112967

Gene position: 936999-937454 (Clockwise)

Preceding gene: 92112964

Following gene: 92112969

Centisome position: 25.35

GC content: 68.2

Gene sequence:

>456_bases
ATGCGCAGCGATACCTTCTACATGCATCGTGCGCTGGATCAAGCGCATCGAGCGCTGGAGGCGGGGGAAGTGCCGGTGGG
CGCGGTGGTGGTTGCACGCGACGGCGACATCGTCGGGACGGGCTTCAATGCGCCGGTGTCGAGCCATGACCCCAGCGCGC
ATGCCGAGGTTCGTGCCCTGCGGGATGCCGCCGAGCGCCTGGGCAACTACCGGCTTGAGGGGTGCACGCTGTTCGTCACG
CTGGAGCCCTGCCTGATGTGTACCGGCGCGATCATCCATGCGCGCGTGGCACGGGTCGTGTATGCGGCCGCCGAACCCCG
CAGTGGCATGGTCGAGTCGCGCGCCAATCTGTTCGCCCAGCCCTGGTTCAATCACCGCGTCGAGGTCGAGGGCGGCGTGC
TGGCCTCGCGTGCCACGCACTTGCTCAAGGCGTTCTTCGCGGCGCGGCGCGAATGA

Upstream 100 bases:

>100_bases
CGACGAGGGTGTCGAGTGGTTGCGTCATGCCGGCATCCTTGTGAACGGTCGTTTTCATACGGTCGTTCCAATTCTATCAG
CATACGGAGACGGCTTCGCG

Downstream 100 bases:

>100_bases
GCGCGAGGCCGATGCCTAAAGCACCGGCGGAACGGTATTGAAGGGTGTCTGGGGGAAGGTGTCGTCGCGCTCGCCGAGAT
GGTGGAACTGACGGCGGCTG

Product: tRNA-adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MRSDTFYMHRALDQAHRALEAGEVPVGAVVVARDGDIVGTGFNAPVSSHDPSAHAEVRALRDAAERLGNYRLEGCTLFVT
LEPCLMCTGAIIHARVARVVYAAAEPRSGMVESRANLFAQPWFNHRVEVEGGVLASRATHLLKAFFAARRE

Sequences:

>Translated_151_residues
MRSDTFYMHRALDQAHRALEAGEVPVGAVVVARDGDIVGTGFNAPVSSHDPSAHAEVRALRDAAERLGNYRLEGCTLFVT
LEPCLMCTGAIIHARVARVVYAAAEPRSGMVESRANLFAQPWFNHRVEVEGGVLASRATHLLKAFFAARRE
>Mature_151_residues
MRSDTFYMHRALDQAHRALEAGEVPVGAVVVARDGDIVGTGFNAPVSSHDPSAHAEVRALRDAAERLGNYRLEGCTLFVT
LEPCLMCTGAIIHARVARVVYAAAEPRSGMVESRANLFAQPWFNHRVEVEGGVLASRATHLLKAFFAARRE

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Escherichia coli, GI145693172, Length=149, Percent_Identity=46.3087248322148, Blast_Score=141, Evalue=2e-35,
Organism=Escherichia coli, GI1786616, Length=155, Percent_Identity=35.4838709677419, Blast_Score=63, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17554608, Length=99, Percent_Identity=39.3939393939394, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17541138, Length=147, Percent_Identity=34.0136054421769, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17555996, Length=98, Percent_Identity=37.7551020408163, Blast_Score=73, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=34.2465753424658, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16456; Mature: 16456

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSDTFYMHRALDQAHRALEAGEVPVGAVVVARDGDIVGTGFNAPVSSHDPSAHAEVRAL
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHH
RDAAERLGNYRLEGCTLFVTLEPCLMCTGAIIHARVARVVYAAAEPRSGMVESRANLFAQ
HHHHHHHCCEEECCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
PWFNHRVEVEGGVLASRATHLLKAFFAARRE
CCCCCEEEECCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRSDTFYMHRALDQAHRALEAGEVPVGAVVVARDGDIVGTGFNAPVSSHDPSAHAEVRAL
CCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCEEECCCCCCCCCCCCCHHHHHHHH
RDAAERLGNYRLEGCTLFVTLEPCLMCTGAIIHARVARVVYAAAEPRSGMVESRANLFAQ
HHHHHHHCCEEECCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
PWFNHRVEVEGGVLASRATHLLKAFFAARRE
CCCCCEEEECCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]