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The map label for this gene is yahK [H]

Identifier: 92112964

GI number: 92112964

Start: 932977

End: 934032

Strand: Direct

Name: yahK [H]

Synonym: Csal_0836

Alternate gene names: 92112964

Gene position: 932977-934032 (Clockwise)

Preceding gene: 92112961

Following gene: 92112967

Centisome position: 25.24

GC content: 63.64

Gene sequence:

>1056_bases
ATGCCACAAGCCAAAGGATACGCTGCGCATTCCGCCGAGTCGGCACTCGAGCCGTACACCTTCGAACGCCGCGAGCCGCG
TCCGGACGATGTCGCCATCGAGATCCTCTACTGCGGCGTTTGCCACAGCGATCTCCACTTCGCACGGGATGACTGGGGCA
TGGCCGCCTATCCGGTGGTGCCGGGCCACGAGATCGTCGGTCGTGTGACCTCGGTGGGCAGCGACGTTGCCAATTTCAAG
GAAGGCGATCTGGTCGGTGTGGGTTGCATGGTCGATTCCTGCCGCCATTGCCAGGCGTGCAACGACGGCGTGGAACAGTA
CTGTGCCGAAGGCTTCACCATGACCTACGGCAGCCCGGACCGCCATGACGGCAGCCTCACCCAGGGTGGCTACTCCGACA
AGGTCACGGTCAGCGAGCGGTTCGTGCTGCGCATGCCGGAAGGCATCGACCTCAAGTCCGCCGCACCGCTGCTGTGCGCG
GGCATCACGACCTATTCGCCGCTCAAGCATTACGGCGTCAAGCCGGGCCACAAGATCGGCGTGATCGGCATGGGCGGCCT
CGGCCACATGGGCGTCAAGCTGGCCAAGGCGCTGGGCGCCGAGGTCACGCTGTTCACGCGCTCCGAAAGCAAGGTGGCCG
AGGCCAAGTCCAATGGCGTCGACCATGTGGTGGTGTCCACCGACGAGGCGCAGATGGCGGCGGTCGCCGAGACCTTCGAC
TTCATGCTCGACACCGTACCCAACCAGCACGATCTGAATCCGTACCTGCAGGCGCTGAAGTACGACGGCACGCACATCCT
GGTCGGGCAGATGCAGCCGCTGGAGCCCGCGGTGATGGGCGCCAACCTGATCTTCCGCCGTCGCGTGCTGGCCGGTTCGC
TGATCGGGGGGATTCCCGAGACGCAAGAAGTGCTGGATTTCTGCGCCGAGAAGGGCATTACCTGCGACGTCGAGATGATC
GACATCCAGAACATCAACGAAGCCTGGGAGCGCATGCAGAAAGGCGACGTGCGTTATCGCTTCGTCATCGACATGGCATC
GATGAAGAACGGCTGA

Upstream 100 bases:

>100_bases
AGATGCCGTGGCATGCCCACACTGTCGGGGTCCGCGATCGCGTCCTGGTGTCGTGTCAGCACGACCGGCGATCGCATTCA
CCATCGAAAGGATATTCGTT

Downstream 100 bases:

>100_bases
GGCCGCGTTTCGGTGCCGACGCACCGATCGCGATAGACCGATCGTACTTGGGCGCGGGGATCTCCCCCGCGCCTTTTTCG
TGTCTGGCAGGTTGCAGAAT

Product: alcohol dehydrogenase GroES-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MPQAKGYAAHSAESALEPYTFERREPRPDDVAIEILYCGVCHSDLHFARDDWGMAAYPVVPGHEIVGRVTSVGSDVANFK
EGDLVGVGCMVDSCRHCQACNDGVEQYCAEGFTMTYGSPDRHDGSLTQGGYSDKVTVSERFVLRMPEGIDLKSAAPLLCA
GITTYSPLKHYGVKPGHKIGVIGMGGLGHMGVKLAKALGAEVTLFTRSESKVAEAKSNGVDHVVVSTDEAQMAAVAETFD
FMLDTVPNQHDLNPYLQALKYDGTHILVGQMQPLEPAVMGANLIFRRRVLAGSLIGGIPETQEVLDFCAEKGITCDVEMI
DIQNINEAWERMQKGDVRYRFVIDMASMKNG

Sequences:

>Translated_351_residues
MPQAKGYAAHSAESALEPYTFERREPRPDDVAIEILYCGVCHSDLHFARDDWGMAAYPVVPGHEIVGRVTSVGSDVANFK
EGDLVGVGCMVDSCRHCQACNDGVEQYCAEGFTMTYGSPDRHDGSLTQGGYSDKVTVSERFVLRMPEGIDLKSAAPLLCA
GITTYSPLKHYGVKPGHKIGVIGMGGLGHMGVKLAKALGAEVTLFTRSESKVAEAKSNGVDHVVVSTDEAQMAAVAETFD
FMLDTVPNQHDLNPYLQALKYDGTHILVGQMQPLEPAVMGANLIFRRRVLAGSLIGGIPETQEVLDFCAEKGITCDVEMI
DIQNINEAWERMQKGDVRYRFVIDMASMKNG
>Mature_350_residues
PQAKGYAAHSAESALEPYTFERREPRPDDVAIEILYCGVCHSDLHFARDDWGMAAYPVVPGHEIVGRVTSVGSDVANFKE
GDLVGVGCMVDSCRHCQACNDGVEQYCAEGFTMTYGSPDRHDGSLTQGGYSDKVTVSERFVLRMPEGIDLKSAAPLLCAG
ITTYSPLKHYGVKPGHKIGVIGMGGLGHMGVKLAKALGAEVTLFTRSESKVAEAKSNGVDHVVVSTDEAQMAAVAETFDF
MLDTVPNQHDLNPYLQALKYDGTHILVGQMQPLEPAVMGANLIFRRRVLAGSLIGGIPETQEVLDFCAEKGITCDVEMID
IQNINEAWERMQKGDVRYRFVIDMASMKNG

Specific function: Unknown

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501933, Length=353, Percent_Identity=25.2124645892351, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI71743840, Length=359, Percent_Identity=23.9554317548747, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI34577061, Length=353, Percent_Identity=24.929178470255, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI262073058, Length=359, Percent_Identity=23.9554317548747, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI4501929, Length=356, Percent_Identity=24.438202247191, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI71565152, Length=361, Percent_Identity=22.7146814404432, Blast_Score=69, Evalue=7e-12,
Organism=Escherichia coli, GI1786518, Length=349, Percent_Identity=55.0143266475645, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI87082401, Length=346, Percent_Identity=37.2832369942197, Blast_Score=214, Evalue=6e-57,
Organism=Escherichia coli, GI87081918, Length=326, Percent_Identity=28.2208588957055, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788073, Length=219, Percent_Identity=30.1369863013699, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI226510992, Length=263, Percent_Identity=28.1368821292776, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI87082125, Length=335, Percent_Identity=25.3731343283582, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790045, Length=274, Percent_Identity=25.1824817518248, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788407, Length=219, Percent_Identity=28.7671232876712, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788075, Length=270, Percent_Identity=24.4444444444444, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787863, Length=210, Percent_Identity=27.1428571428571, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71988145, Length=333, Percent_Identity=28.5285285285285, Blast_Score=144, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17562584, Length=329, Percent_Identity=27.0516717325228, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17562582, Length=331, Percent_Identity=28.0966767371601, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25146526, Length=365, Percent_Identity=26.027397260274, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562876, Length=342, Percent_Identity=23.0994152046784, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71997431, Length=367, Percent_Identity=25.8855585831063, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17562878, Length=204, Percent_Identity=26.9607843137255, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17565904, Length=351, Percent_Identity=24.7863247863248, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323980, Length=353, Percent_Identity=37.9603399433428, Blast_Score=194, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6319949, Length=331, Percent_Identity=35.3474320241692, Blast_Score=174, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6324486, Length=349, Percent_Identity=29.7994269340974, Blast_Score=155, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6323961, Length=344, Percent_Identity=29.0697674418605, Blast_Score=150, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6323729, Length=338, Percent_Identity=28.9940828402367, Blast_Score=144, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6319621, Length=355, Percent_Identity=27.3239436619718, Blast_Score=143, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6319258, Length=352, Percent_Identity=25.5681818181818, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320033, Length=362, Percent_Identity=25.6906077348066, Blast_Score=76, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6319955, Length=213, Percent_Identity=30.5164319248826, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322619, Length=213, Percent_Identity=30.5164319248826, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17737895, Length=362, Percent_Identity=24.3093922651934, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI17737897, Length=237, Percent_Identity=25.7383966244726, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR006140
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 38125; Mature: 37994

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00059 ADH_ZINC ; PS00065 D_2_HYDROXYACID_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQAKGYAAHSAESALEPYTFERREPRPDDVAIEILYCGVCHSDLHFARDDWGMAAYPVV
CCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCHHCCCCCCCEEECCC
PGHEIVGRVTSVGSDVANFKEGDLVGVGCMVDSCRHCQACNDGVEQYCAEGFTMTYGSPD
CCHHHHHHHHHHCCHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
RHDGSLTQGGYSDKVTVSERFVLRMPEGIDLKSAAPLLCAGITTYSPLKHYGVKPGHKIG
CCCCCCCCCCCCCEEEECCEEEEECCCCCCCCCCCCCEEECCCCCCHHHHCCCCCCCEEE
VIGMGGLGHMGVKLAKALGAEVTLFTRSESKVAEAKSNGVDHVVVSTDEAQMAAVAETFD
EEEECCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHH
FMLDTVPNQHDLNPYLQALKYDGTHILVGQMQPLEPAVMGANLIFRRRVLAGSLIGGIPE
HHHHCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
TQEVLDFCAEKGITCDVEMIDIQNINEAWERMQKGDVRYRFVIDMASMKNG
HHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCCC
>Mature Secondary Structure 
PQAKGYAAHSAESALEPYTFERREPRPDDVAIEILYCGVCHSDLHFARDDWGMAAYPVV
CCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCHHCCCCCCCEEECCC
PGHEIVGRVTSVGSDVANFKEGDLVGVGCMVDSCRHCQACNDGVEQYCAEGFTMTYGSPD
CCHHHHHHHHHHCCHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCC
RHDGSLTQGGYSDKVTVSERFVLRMPEGIDLKSAAPLLCAGITTYSPLKHYGVKPGHKIG
CCCCCCCCCCCCCEEEECCEEEEECCCCCCCCCCCCCEEECCCCCCHHHHCCCCCCCEEE
VIGMGGLGHMGVKLAKALGAEVTLFTRSESKVAEAKSNGVDHVVVSTDEAQMAAVAETFD
EEEECCCHHHHHHHHHHCCCEEEEEECCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHH
FMLDTVPNQHDLNPYLQALKYDGTHILVGQMQPLEPAVMGANLIFRRRVLAGSLIGGIPE
HHHHCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
TQEVLDFCAEKGITCDVEMIDIQNINEAWERMQKGDVRYRFVIDMASMKNG
HHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]