Click here to switch to the map view.

The map label for this gene is deoR [H]

Identifier: 92112960

GI number: 92112960

Start: 927633

End: 928418

Strand: Direct

Name: deoR [H]

Synonym: Csal_0832

Alternate gene names: 92112960

Gene position: 927633-928418 (Clockwise)

Preceding gene: 92112952

Following gene: 92112961

Centisome position: 25.09

GC content: 64.63

Gene sequence:

>786_bases
ATGAATAGCCGCAGTGCGGCGCGCCTTCAATGGCTACAGGACACCCTGCGCGCGGAAGGCATGTTGCCGATTGCCGAGGC
CGCCCAGCGCTGTCAGGTATCGGAGATGACCATACGCCGCGATATCGCCGCCAGCCAGGACACCATCGTCTCGCTGGGCG
GGCGTTTGCTGCTGGCCGAGCATCCGCAGGTTGCCACCGGATACGACTTCGCCACTCAGCAGGACAGTTTCGCCCAGGCC
AAGCAGCGCATGTGCGAGGAAGCGGCACGCATGGTCGAGGCCGACGACACGATCTTCGTGGACTGCGGGACGACGCTGAT
CCCGCTGTTTGCCAAGCTCGATCCCGATCTGCCGCTGACGGTGGTGACCTATGCCCTCAACGTCGCCAACGCCATCGAGC
AACTCGCCTTGCCTCACGTGCGGCTGGTGTTGCTGGGCGGCCTCTATTATCCGGTGTCGCAATCCTTCGGTGGCGAGGAA
CTGGTCACCGCGATTCGTCGCCTGGGGATCAACAAGGCGTTCATTTCCGCCGCCGGGGTGCGTGTCGACAAGGGCGTGAG
CTGCTTCCATTTCCACGAGGTGGTGCCCAAGCAGGTGGCTCTGGAAACCGCCGTGCAGCGTATCCTCATTGCCGACGAGA
GCAAGCTCGATCGGGTGCGGCCGGCCTTTTTCGCCGAGCTGGAAGCGTTCGACGTGATGCTGACCAGCGGCGCTGCGGGC
GAGACGCTGCGTGACACGCTGGCGACGCGTGCCGATCGCGCCTGGCCGACGGTCAAGGTGCTGTGA

Upstream 100 bases:

>100_bases
TTTGTTAATTTTCTAACAGAAATTTTGTGGCTAAGCTAACAAAATGTGCCGGAGAAGGGCGAGCGATCTCGTCGACCGGT
ATGCCGAGGGAGATGTGCAC

Downstream 100 bases:

>100_bases
TGGCGCAGCGATGGCGGGCGGCTGCCATCATCGTGTGCGGTAATTCACATCGGCGCGCGGGTGGCAGACAGCGGACATGA
CGTTTCCTCTCTCGCTGGCG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MNSRSAARLQWLQDTLRAEGMLPIAEAAQRCQVSEMTIRRDIAASQDTIVSLGGRLLLAEHPQVATGYDFATQQDSFAQA
KQRMCEEAARMVEADDTIFVDCGTTLIPLFAKLDPDLPLTVVTYALNVANAIEQLALPHVRLVLLGGLYYPVSQSFGGEE
LVTAIRRLGINKAFISAAGVRVDKGVSCFHFHEVVPKQVALETAVQRILIADESKLDRVRPAFFAELEAFDVMLTSGAAG
ETLRDTLATRADRAWPTVKVL

Sequences:

>Translated_261_residues
MNSRSAARLQWLQDTLRAEGMLPIAEAAQRCQVSEMTIRRDIAASQDTIVSLGGRLLLAEHPQVATGYDFATQQDSFAQA
KQRMCEEAARMVEADDTIFVDCGTTLIPLFAKLDPDLPLTVVTYALNVANAIEQLALPHVRLVLLGGLYYPVSQSFGGEE
LVTAIRRLGINKAFISAAGVRVDKGVSCFHFHEVVPKQVALETAVQRILIADESKLDRVRPAFFAELEAFDVMLTSGAAG
ETLRDTLATRADRAWPTVKVL
>Mature_261_residues
MNSRSAARLQWLQDTLRAEGMLPIAEAAQRCQVSEMTIRRDIAASQDTIVSLGGRLLLAEHPQVATGYDFATQQDSFAQA
KQRMCEEAARMVEADDTIFVDCGTTLIPLFAKLDPDLPLTVVTYALNVANAIEQLALPHVRLVLLGGLYYPVSQSFGGEE
LVTAIRRLGINKAFISAAGVRVDKGVSCFHFHEVVPKQVALETAVQRILIADESKLDRVRPAFFAELEAFDVMLTSGAAG
ETLRDTLATRADRAWPTVKVL

Specific function: This protein is one of the repressors that regulate the expression of deoCABD genes, which encode nucleotide and deoxy ribonucleotide catabolizing enzymes. It also negatively regulates the expression of nupG (a transport protein) and tsx (a pore- forming

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787063, Length=235, Percent_Identity=34.8936170212766, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1789059, Length=256, Percent_Identity=26.953125, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI226510968, Length=236, Percent_Identity=29.6610169491525, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790753, Length=256, Percent_Identity=26.171875, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789829, Length=234, Percent_Identity=23.9316239316239, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788069, Length=236, Percent_Identity=24.1525423728814, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1787540, Length=243, Percent_Identity=25.5144032921811, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28558; Mature: 28558

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSRSAARLQWLQDTLRAEGMLPIAEAAQRCQVSEMTIRRDIAASQDTIVSLGGRLLLAE
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEEC
HPQVATGYDFATQQDSFAQAKQRMCEEAARMVEADDTIFVDCGTTLIPLFAKLDPDLPLT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCCHH
VVTYALNVANAIEQLALPHVRLVLLGGLYYPVSQSFGGEELVTAIRRLGINKAFISAAGV
HHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHCCC
RVDKGVSCFHFHEVVPKQVALETAVQRILIADESKLDRVRPAFFAELEAFDVMLTSGAAG
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEECCCCC
ETLRDTLATRADRAWPTVKVL
HHHHHHHHHHHCCCCCCEEEC
>Mature Secondary Structure
MNSRSAARLQWLQDTLRAEGMLPIAEAAQRCQVSEMTIRRDIAASQDTIVSLGGRLLLAE
CCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEEC
HPQVATGYDFATQQDSFAQAKQRMCEEAARMVEADDTIFVDCGTTLIPLFAKLDPDLPLT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCCCHH
VVTYALNVANAIEQLALPHVRLVLLGGLYYPVSQSFGGEELVTAIRRLGINKAFISAAGV
HHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHCCC
RVDKGVSCFHFHEVVPKQVALETAVQRILIADESKLDRVRPAFFAELEAFDVMLTSGAAG
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHEECCCCC
ETLRDTLATRADRAWPTVKVL
HHHHHHHHHHHCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]