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The map label for this gene is trxA [H]

Identifier: 92112715

GI number: 92112715

Start: 647882

End: 648211

Strand: Direct

Name: trxA [H]

Synonym: Csal_0582

Alternate gene names: 92112715

Gene position: 647882-648211 (Clockwise)

Preceding gene: 92112713

Following gene: 92112716

Centisome position: 17.53

GC content: 67.27

Gene sequence:

>330_bases
ATGAGCGAGCGATTGATCGAGGTCACGGACGACACCTTCGAGGAGCGAGTCCTGGAGCCCCAGACGCCCGTCCTGGTGGC
GTTCGTGGCCGCCTGGTGCGCGCCCTGTCGGGAGCTGCGGTCGCGTTTGTCCGCCCTGGCTGCCGCCCGCGACGCCCTGC
AGGTGGCATTGTGCGACGTGGACCTCAACCCGGCCACGGCGGACAAGTACGGCGTACGGGGCATGCCGACCCTGGTCCTG
TTCGTCGGCGCGAGCATGGAAAGTTCGCGGGTGGGGGCATTGTCCACGACACAACTCGAAGGCTGGCTCGATGCGCAACT
GACGTCTTGA

Upstream 100 bases:

>100_bases
CTTTGCACAGTAATGGAGCAAGGTTGCGGGGCTGTCCGGTGCTTGTCAATTACCGCCATGTGGCGTTCGATGACAGAATA
CGACACAAGAGAGGGCCGAC

Downstream 100 bases:

>100_bases
ACCGTTGCATGCCGTGCGGTCGCGCCGGCAGGGAGCCGAAGGGGCTTGCGTTTGCCTGTCGGCTTGACTACCATCGGGTT
GTTCGCCTGTTCCGAATGCT

Product: thioredoxin-related

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 109; Mature: 108

Protein sequence:

>109_residues
MSERLIEVTDDTFEERVLEPQTPVLVAFVAAWCAPCRELRSRLSALAAARDALQVALCDVDLNPATADKYGVRGMPTLVL
FVGASMESSRVGALSTTQLEGWLDAQLTS

Sequences:

>Translated_109_residues
MSERLIEVTDDTFEERVLEPQTPVLVAFVAAWCAPCRELRSRLSALAAARDALQVALCDVDLNPATADKYGVRGMPTLVL
FVGASMESSRVGALSTTQLEGWLDAQLTS
>Mature_108_residues
SERLIEVTDDTFEERVLEPQTPVLVAFVAAWCAPCRELRSRLSALAAARDALQVALCDVDLNPATADKYGVRGMPTLVLF
VGASMESSRVGALSTTQLEGWLDAQLTS

Specific function: Component of the thioredoxin-thioredoxin reductase system. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI87082331, Length=108, Percent_Identity=44.4444444444444, Blast_Score=100, Evalue=3e-23,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 11785; Mature: 11653

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERLIEVTDDTFEERVLEPQTPVLVAFVAAWCAPCRELRSRLSALAAARDALQVALCDV
CCCCEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
DLNPATADKYGVRGMPTLVLFVGASMESSRVGALSTTQLEGWLDAQLTS
CCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHCCHHCCCCCC
>Mature Secondary Structure 
SERLIEVTDDTFEERVLEPQTPVLVAFVAAWCAPCRELRSRLSALAAARDALQVALCDV
CCCEEECCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECC
DLNPATADKYGVRGMPTLVLFVGASMESSRVGALSTTQLEGWLDAQLTS
CCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHCCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7496529 [H]