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The map label for this gene is frr

Identifier: 92112699

GI number: 92112699

Start: 628206

End: 628763

Strand: Direct

Name: frr

Synonym: Csal_0566

Alternate gene names: 92112699

Gene position: 628206-628763 (Clockwise)

Preceding gene: 92112698

Following gene: 92112700

Centisome position: 16.99

GC content: 60.39

Gene sequence:

>558_bases
GTGATCAACGACATCAAGAAAGACGCCGACGCGCGCATGAAGAAAAGCGTCGAGGCGTTGAACGCCAATTTTCACAAGAT
TCGTACCGGGCGCGCGCATCCGAGCCTGCTGGATGCGGTCACCGTTGAGTATTACGGCAGCGAGATGCCGCTCAACCAGG
TGGCCAGCGTCAACGTGGAAGATGCCCGCACACTGGCGGTCGTGCCCTGGGAAAAGAGCATGGTGCCCAAGGTCGAAAAG
GCCATCATGACCTCCGACCTGGGCCTCAATCCCGCCGCGGCAGGCAACGTGATTCGCGTGCCCCTGCCGCCGCTGACCGA
GGAAACGCGGCGCAACTACATCAAGCAGGCGCGTGGCGAGGCGGAAAACGCGCGCGTGGCGGTACGCAACGTGCGCCGCG
ATGCCAATGGCGATCTCAAGTCGCTTCTCAAGGAGAAGGAGATCACCGAGGATGAAGAGCGTCACGCCATCGACGAGATC
CAGAAGCTGACCGACAAGTACGTCACCGAGATCGACAAGCTTCTGGAAACCAAGGAACACGACCTGCTGCAGGTCTAA

Upstream 100 bases:

>100_bases
GACATGCCGGTGCGCGTGTTCGATATGACCAAGCCGGGAGCCTTGCTCAACCTGGTAGTGGGTGGCAAGGAAGGAACGCT
GGTAGACAGAGGCTGAAACC

Downstream 100 bases:

>100_bases
GAGGGTGGCCGACGGGCAGGGCGCCCGTCGGTCTCCACGCAACGGGATCCCATGACCTCACAGCCGTTTTCCCCATCCCG
CGCGGGCGAGTTGCCGCGCC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MINDIKKDADARMKKSVEALNANFHKIRTGRAHPSLLDAVTVEYYGSEMPLNQVASVNVEDARTLAVVPWEKSMVPKVEK
AIMTSDLGLNPAAAGNVIRVPLPPLTEETRRNYIKQARGEAENARVAVRNVRRDANGDLKSLLKEKEITEDEERHAIDEI
QKLTDKYVTEIDKLLETKEHDLLQV

Sequences:

>Translated_185_residues
MINDIKKDADARMKKSVEALNANFHKIRTGRAHPSLLDAVTVEYYGSEMPLNQVASVNVEDARTLAVVPWEKSMVPKVEK
AIMTSDLGLNPAAAGNVIRVPLPPLTEETRRNYIKQARGEAENARVAVRNVRRDANGDLKSLLKEKEITEDEERHAIDEI
QKLTDKYVTEIDKLLETKEHDLLQV
>Mature_185_residues
MINDIKKDADARMKKSVEALNANFHKIRTGRAHPSLLDAVTVEYYGSEMPLNQVASVNVEDARTLAVVPWEKSMVPKVEK
AIMTSDLGLNPAAAGNVIRVPLPPLTEETRRNYIKQARGEAENARVAVRNVRRDANGDLKSLLKEKEITEDEERHAIDEI
QKLTDKYVTEIDKLLETKEHDLLQV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=174, Percent_Identity=31.6091954022989, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1786368, Length=185, Percent_Identity=61.0810810810811, Blast_Score=231, Evalue=3e-62,
Organism=Drosophila melanogaster, GI24661488, Length=176, Percent_Identity=28.9772727272727, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_CHRSD (Q1R030)

Other databases:

- EMBL:   CP000285
- RefSeq:   YP_572627.1
- ProteinModelPortal:   Q1R030
- SMR:   Q1R030
- STRING:   Q1R030
- GeneID:   4026167
- GenomeReviews:   CP000285_GR
- KEGG:   csa:Csal_0566
- NMPDR:   fig|290398.4.peg.268
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- BioCyc:   CSAL290398:CSAL_0566-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20838; Mature: 20838

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINDIKKDADARMKKSVEALNANFHKIRTGRAHPSLLDAVTVEYYGSEMPLNQVASVNVE
CCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCC
DARTLAVVPWEKSMVPKVEKAIMTSDLGLNPAAAGNVIRVPLPPLTEETRRNYIKQARGE
CCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCC
AENARVAVRNVRRDANGDLKSLLKEKEITEDEERHAIDEIQKLTDKYVTEIDKLLETKEH
CHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLQV
HHHCC
>Mature Secondary Structure
MINDIKKDADARMKKSVEALNANFHKIRTGRAHPSLLDAVTVEYYGSEMPLNQVASVNVE
CCCCHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHCCCCC
DARTLAVVPWEKSMVPKVEKAIMTSDLGLNPAAAGNVIRVPLPPLTEETRRNYIKQARGE
CCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHCCC
AENARVAVRNVRRDANGDLKSLLKEKEITEDEERHAIDEIQKLTDKYVTEIDKLLETKEH
CHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLLQV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA