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The map label for this gene is clpB [H]

Identifier: 92112632

GI number: 92112632

Start: 546883

End: 549465

Strand: Direct

Name: clpB [H]

Synonym: Csal_0499

Alternate gene names: 92112632

Gene position: 546883-549465 (Clockwise)

Preceding gene: 92112631

Following gene: 92112634

Centisome position: 14.79

GC content: 63.61

Gene sequence:

>2583_bases
ATGCGAATCGATCGAATGACCAGCAAGCTGCAGAACGCCCTGGCCGAGGCACAATCCCTGGCAGTGGGGCGCAGTCACAA
TCAGCTCGATCCCGGGCATGTGCTGATGGCGCTCGTCGAAGCGCAGGAAAGCGGCATCAAGGGACTGGTGCAGAAGGCCG
GCGGCGATACCGCGCGGCTGCGCGACGGCCTGTCCCAATACCTCGATGGCTTGCCCAGTGTCGGCCAGTTCGATGGCAAT
GTGACCATGGGGCAGGAACTGGCGCGGCTGTTCAACTTCGCCGATCGCGAAGCGCAGAAACGTGGCGACCAATACATCGC
CAGCGAGCTGGTGGTGCTGGCGGCATTGGAAATGAAAAGCGCCATCAGCAAGGTGCTCCAGCAGGCCGGTCTGGATGTCC
AGTCCGTGCGGAGTGCCATCGACAGTCTGCGCGGAGGCAGCAAGGTGGATGATGCCTCGGCCGAGGAGAGCCGCGAGGCC
CTGGACAAGTACACCACCGACCTGACCCAGCGCGCCGGAGAGGGCAAGCTCGATCCGGTGATCGGTCGTGACGACGAGAT
CCGCCGCACGATCCAGGTGCTGCAGCGGCGTACCAAGAACAATCCGGTATTGATCGGCGAGCCCGGTGTGGGCAAGACCG
CCATCGTCGAGGGGCTGGCGCAGCGCATCGTCAATGGCGAGGTGCCCGAGGGCCTCAAGGACAAGCGTGTGCTGGCGCTG
GACATGGGCTCGTTGCTGGCTGGCGCCAAGTACCGGGGCGAGTTCGAGGAACGTCTCAAGGCCGTGCTCGGGGAGCTGGC
CAAGGAGGAGGGGCGTGTCATCCTGTTCGTCGATGAGCTGCATACCATGGTCGGCGCCGGCAAGGCCGAGGGCGCGATGG
ACGCCGGCAACATGCTCAAGCCGGCATTGGCGCGGGGCGAATTGCACTGCGTCGGGGCCACTACGCTGGACGAATATCGT
CAGCACATCGAGAAGGATGCGGCACTCGAACGGCGTTTCCAGAAAGTCCTGGTCGACGAGCCCAACGAAGAAGACACCGT
GGCGATCCTGCGTGGCCTCAAGGAGCGTTACGAGGTCCATCATGGTGTCGATATCACCGATGGTGCCATCATCGCCGCGG
CCAAGCTGTCGACCCGCTACATCACCGATCGTCAGTTGCCCGACAAGGCCATCGACCTGATCGACGAGGCGGCCTCCCGG
ATCCGCATGGAACTCGACTCCATGCCCGAGGAGATGGACCGTCTCGACCGGCGGCTGATTCAGCTCAAGATGGAGCGCGA
AGCGCTGAAGAAGGAGACCGACGAGGCCACCAAGAAGCGCCTCGACTCGCTCGAAGCGCAGATCGAGTCGCTAGAGCGCG
AGTACGCCGACCTCGAAGAGGTGTGGAAAGCCGAGAAGGCCAGCATCCAGGGGGCGGCACAGTTCAAGGCGGAGCTCGAG
CAGGCGCGTATCGATCTCGAGGCGGCACGCCGTCAGGGGGATCTGGGCCGCATGTCCGAGCTGCAATACGGGGTGATTCC
CAAGCTCGAGAAGCAGATCGCCGAGGCGAGCGAGCAGGAAACCGATACCGCCAAGCATCAACTGCTGCGTTCCAACGTCA
CCGAAGAGGAGATCGCCGAGGTGGTCTCTCGCTGGACGGGGATTCCGGTGTCCAAGATGCTCGAAGGCGAACGCGACAAA
TTGCTGCGCATGGAAGAGGCGCTGCACGAGCGCGTGATCGGGCAGGATGAGGCGGTGACCGCCGTGGCCAATGCCGTGCG
GCGTTCGCGTGCGGGACTCGCCGATCCGGGACGTCCCAATGGGTCCTTCCTGTTCCTGGGGCCCACCGGGGTAGGCAAGA
CCGAGCTGTGCAAGTCGCTCGCCAGCTTCCTCTTCGATACCGAGGAGGCCATGGTGCGCATCGACATGTCCGAGTTCATG
GAGAAGCATTCCGTGGCGCGGCTGATCGGGGCGCCGCCGGGCTATGTGGGATACGAAGAAGGCGGTTACCTGACCGAAGC
GGTACGCCGCAAGCCTTACTCCGTGCTGCTGCTCGACGAGGTCGAGAAGGCGCACGCGGATGTCTTCAATATCCTGCTCC
AGGTGCTCGAGGACGGCCGTCTCACCGATGGACAGGGGCGCACGGTGGATTTCCGCAATACGGTGATCGTGATGACCTCC
AACCTGGGATCGGACATCATTCAGCGCATGGGCGGCGACGATGCCGATTATGGCGCGATGCGCGATGCCGTCATGGGAGT
CGTGGGCGATCATTTCCGTCCGGAGCTGATCAACCGCATCGACGAAGTGGTGGTGTTCCACGCACTGGGCCAGGAGCAGA
TCCAGTCCATTGCCGGCATCCAGCTCGAACGCCTCAAGGCGCGTCTCGCCGAGCGCGAGATCCGTCTCGAGGTCAGCGAC
GATGCCCTGGCACAATTGGCGGTGGTCGGCTTCGATCCGGTATTCGGTGCGCGTCCGCTCAAGCGTGCCATCCAGAGCCG
GATCGAAAACCCGCTGGCGCAGGAGCTGCTCGCCGGCAACTTTGCGGCGGGCGATACCATCAAGGTGACGGCCGAGGATG
GTCATCTGGCCTTTGCCAAGTAA

Upstream 100 bases:

>100_bases
CGCCAGTGACTTGAAACGCCTCCAGCATACCTCCATTGATGATGTCAACATGAAATGACTTGGCGGCGCGCGCCGGTGCG
CCGCATTGGAGGAGGGTTCG

Downstream 100 bases:

>100_bases
AGCTGGCGCTCGCCAGTGCCGGAAAAGCCCGCCCCTTCGGGGGCGGGTTTTTTTCATGCCGCTATGCGGGCGCTGCAACG
CAGCAGCAGCGCGCGTTCAG

Product: ATPase AAA-2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 860; Mature: 860

Protein sequence:

>860_residues
MRIDRMTSKLQNALAEAQSLAVGRSHNQLDPGHVLMALVEAQESGIKGLVQKAGGDTARLRDGLSQYLDGLPSVGQFDGN
VTMGQELARLFNFADREAQKRGDQYIASELVVLAALEMKSAISKVLQQAGLDVQSVRSAIDSLRGGSKVDDASAEESREA
LDKYTTDLTQRAGEGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKDKRVLAL
DMGSLLAGAKYRGEFEERLKAVLGELAKEEGRVILFVDELHTMVGAGKAEGAMDAGNMLKPALARGELHCVGATTLDEYR
QHIEKDAALERRFQKVLVDEPNEEDTVAILRGLKERYEVHHGVDITDGAIIAAAKLSTRYITDRQLPDKAIDLIDEAASR
IRMELDSMPEEMDRLDRRLIQLKMEREALKKETDEATKKRLDSLEAQIESLEREYADLEEVWKAEKASIQGAAQFKAELE
QARIDLEAARRQGDLGRMSELQYGVIPKLEKQIAEASEQETDTAKHQLLRSNVTEEEIAEVVSRWTGIPVSKMLEGERDK
LLRMEEALHERVIGQDEAVTAVANAVRRSRAGLADPGRPNGSFLFLGPTGVGKTELCKSLASFLFDTEEAMVRIDMSEFM
EKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVLLLDEVEKAHADVFNILLQVLEDGRLTDGQGRTVDFRNTVIVMTS
NLGSDIIQRMGGDDADYGAMRDAVMGVVGDHFRPELINRIDEVVVFHALGQEQIQSIAGIQLERLKARLAEREIRLEVSD
DALAQLAVVGFDPVFGARPLKRAIQSRIENPLAQELLAGNFAAGDTIKVTAEDGHLAFAK

Sequences:

>Translated_860_residues
MRIDRMTSKLQNALAEAQSLAVGRSHNQLDPGHVLMALVEAQESGIKGLVQKAGGDTARLRDGLSQYLDGLPSVGQFDGN
VTMGQELARLFNFADREAQKRGDQYIASELVVLAALEMKSAISKVLQQAGLDVQSVRSAIDSLRGGSKVDDASAEESREA
LDKYTTDLTQRAGEGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKDKRVLAL
DMGSLLAGAKYRGEFEERLKAVLGELAKEEGRVILFVDELHTMVGAGKAEGAMDAGNMLKPALARGELHCVGATTLDEYR
QHIEKDAALERRFQKVLVDEPNEEDTVAILRGLKERYEVHHGVDITDGAIIAAAKLSTRYITDRQLPDKAIDLIDEAASR
IRMELDSMPEEMDRLDRRLIQLKMEREALKKETDEATKKRLDSLEAQIESLEREYADLEEVWKAEKASIQGAAQFKAELE
QARIDLEAARRQGDLGRMSELQYGVIPKLEKQIAEASEQETDTAKHQLLRSNVTEEEIAEVVSRWTGIPVSKMLEGERDK
LLRMEEALHERVIGQDEAVTAVANAVRRSRAGLADPGRPNGSFLFLGPTGVGKTELCKSLASFLFDTEEAMVRIDMSEFM
EKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVLLLDEVEKAHADVFNILLQVLEDGRLTDGQGRTVDFRNTVIVMTS
NLGSDIIQRMGGDDADYGAMRDAVMGVVGDHFRPELINRIDEVVVFHALGQEQIQSIAGIQLERLKARLAEREIRLEVSD
DALAQLAVVGFDPVFGARPLKRAIQSRIENPLAQELLAGNFAAGDTIKVTAEDGHLAFAK
>Mature_860_residues
MRIDRMTSKLQNALAEAQSLAVGRSHNQLDPGHVLMALVEAQESGIKGLVQKAGGDTARLRDGLSQYLDGLPSVGQFDGN
VTMGQELARLFNFADREAQKRGDQYIASELVVLAALEMKSAISKVLQQAGLDVQSVRSAIDSLRGGSKVDDASAEESREA
LDKYTTDLTQRAGEGKLDPVIGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKDKRVLAL
DMGSLLAGAKYRGEFEERLKAVLGELAKEEGRVILFVDELHTMVGAGKAEGAMDAGNMLKPALARGELHCVGATTLDEYR
QHIEKDAALERRFQKVLVDEPNEEDTVAILRGLKERYEVHHGVDITDGAIIAAAKLSTRYITDRQLPDKAIDLIDEAASR
IRMELDSMPEEMDRLDRRLIQLKMEREALKKETDEATKKRLDSLEAQIESLEREYADLEEVWKAEKASIQGAAQFKAELE
QARIDLEAARRQGDLGRMSELQYGVIPKLEKQIAEASEQETDTAKHQLLRSNVTEEEIAEVVSRWTGIPVSKMLEGERDK
LLRMEEALHERVIGQDEAVTAVANAVRRSRAGLADPGRPNGSFLFLGPTGVGKTELCKSLASFLFDTEEAMVRIDMSEFM
EKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVLLLDEVEKAHADVFNILLQVLEDGRLTDGQGRTVDFRNTVIVMTS
NLGSDIIQRMGGDDADYGAMRDAVMGVVGDHFRPELINRIDEVVVFHALGQEQIQSIAGIQLERLKARLAEREIRLEVSD
DALAQLAVVGFDPVFGARPLKRAIQSRIENPLAQELLAGNFAAGDTIKVTAEDGHLAFAK

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=322, Percent_Identity=36.3354037267081, Blast_Score=207, Evalue=4e-53,
Organism=Escherichia coli, GI1788943, Length=849, Percent_Identity=69.2579505300353, Blast_Score=1197, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=259, Percent_Identity=52.5096525096525, Blast_Score=275, Evalue=8e-75,
Organism=Saccharomyces cerevisiae, GI6320464, Length=710, Percent_Identity=54.2253521126761, Blast_Score=778, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=864, Percent_Identity=41.6666666666667, Blast_Score=673, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 94730; Mature: 94730

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIDRMTSKLQNALAEAQSLAVGRSHNQLDPGHVLMALVEAQESGIKGLVQKAGGDTARL
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RDGLSQYLDGLPSVGQFDGNVTMGQELARLFNFADREAQKRGDQYIASELVVLAALEMKS
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AISKVLQQAGLDVQSVRSAIDSLRGGSKVDDASAEESREALDKYTTDLTQRAGEGKLDPV
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
IGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKDKRVLAL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
DMGSLLAGAKYRGEFEERLKAVLGELAKEEGRVILFVDELHTMVGAGKAEGAMDAGNMLK
EHHHHHHCCHHCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALARGELHCVGATTLDEYRQHIEKDAALERRFQKVLVDEPNEEDTVAILRGLKERYEVH
HHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
HGVDITDGAIIAAAKLSTRYITDRQLPDKAIDLIDEAASRIRMELDSMPEEMDRLDRRLI
CCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
QLKMEREALKKETDEATKKRLDSLEAQIESLEREYADLEEVWKAEKASIQGAAQFKAELE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QARIDLEAARRQGDLGRMSELQYGVIPKLEKQIAEASEQETDTAKHQLLRSNVTEEEIAE
HHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VVSRWTGIPVSKMLEGERDKLLRMEEALHERVIGQDEAVTAVANAVRRSRAGLADPGRPN
HHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCC
GSFLFLGPTGVGKTELCKSLASFLFDTEEAMVRIDMSEFMEKHSVARLIGAPPGYVGYEE
CCEEEECCCCCCHHHHHHHHHHHHHCCHHHHHEECHHHHHHHHHHHHHHCCCCCCCCCCC
GGYLTEAVRRKPYSVLLLDEVEKAHADVFNILLQVLEDGRLTDGQGRTVDFRNTVIVMTS
CCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEEC
NLGSDIIQRMGGDDADYGAMRDAVMGVVGDHFRPELINRIDEVVVFHALGQEQIQSIAGI
CCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCH
QLERLKARLAEREIRLEVSDDALAQLAVVGFDPVFGARPLKRAIQSRIENPLAQELLAGN
HHHHHHHHHHHHHHEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCC
FAAGDTIKVTAEDGHLAFAK
CCCCCEEEEEECCCCEECCC
>Mature Secondary Structure
MRIDRMTSKLQNALAEAQSLAVGRSHNQLDPGHVLMALVEAQESGIKGLVQKAGGDTARL
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RDGLSQYLDGLPSVGQFDGNVTMGQELARLFNFADREAQKRGDQYIASELVVLAALEMKS
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AISKVLQQAGLDVQSVRSAIDSLRGGSKVDDASAEESREALDKYTTDLTQRAGEGKLDPV
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
IGRDDEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKDKRVLAL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEE
DMGSLLAGAKYRGEFEERLKAVLGELAKEEGRVILFVDELHTMVGAGKAEGAMDAGNMLK
EHHHHHHCCHHCCHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALARGELHCVGATTLDEYRQHIEKDAALERRFQKVLVDEPNEEDTVAILRGLKERYEVH
HHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
HGVDITDGAIIAAAKLSTRYITDRQLPDKAIDLIDEAASRIRMELDSMPEEMDRLDRRLI
CCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
QLKMEREALKKETDEATKKRLDSLEAQIESLEREYADLEEVWKAEKASIQGAAQFKAELE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QARIDLEAARRQGDLGRMSELQYGVIPKLEKQIAEASEQETDTAKHQLLRSNVTEEEIAE
HHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
VVSRWTGIPVSKMLEGERDKLLRMEEALHERVIGQDEAVTAVANAVRRSRAGLADPGRPN
HHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCC
GSFLFLGPTGVGKTELCKSLASFLFDTEEAMVRIDMSEFMEKHSVARLIGAPPGYVGYEE
CCEEEECCCCCCHHHHHHHHHHHHHCCHHHHHEECHHHHHHHHHHHHHHCCCCCCCCCCC
GGYLTEAVRRKPYSVLLLDEVEKAHADVFNILLQVLEDGRLTDGQGRTVDFRNTVIVMTS
CCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCEEEEEEC
NLGSDIIQRMGGDDADYGAMRDAVMGVVGDHFRPELINRIDEVVVFHALGQEQIQSIAGI
CCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCH
QLERLKARLAEREIRLEVSDDALAQLAVVGFDPVFGARPLKRAIQSRIENPLAQELLAGN
HHHHHHHHHHHHHHEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHCC
FAAGDTIKVTAEDGHLAFAK
CCCCCEEEEEECCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]