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The map label for this gene is lspA [H]

Identifier: 92112615

GI number: 92112615

Start: 532800

End: 533345

Strand: Direct

Name: lspA [H]

Synonym: Csal_0482

Alternate gene names: 92112615

Gene position: 532800-533345 (Clockwise)

Preceding gene: 92112614

Following gene: 92112616

Centisome position: 14.41

GC content: 61.9

Gene sequence:

>546_bases
ATGAACGACGCTTCAACGTCTGAAAAAATCGCGGCAGCACCTGCCATGCGCCGTCCGCTGCGCTGGCTGTGGCTGGCCTT
GCTGGTCGTCGTCCTCGATCTGGGCAGCAAGTTCGTGGCCAGCGCCTACCTGGTGTACGGCCAGCCGGTCGAGGTACTGC
CGGTGTTCAACCTGACCCTCTTGCACAATACCGGCGCGGCGTTCAGTTTCCTGGCCGAGCATGCCGGTTGGCAACGGTGG
CTGTTCGCGGCCATCGCCATCGGTGTGAGCATCGGCCTGACCGTGTGGCTGACGCGTCTCAAGGCGCATGAGCGGCTCTC
GGCCATTGCCATCGTGCTGGTCATCGGCGGAGCGCTGGGCAACCTGTATGACCGTCTGGTGCACGGCTATGTGGTCGACT
TCCTGTCGTTCCACTGGCAAGACTATTACTTTCCCGCCTTTAACTTGGCGGACACCGCCATCACCTTGGGGGCCATGGGC
CTGATTCTGGCATCCCTGCGCGATGACCGGCGAAACACGACGCAAAAAGAGACGCCTCATGAGTGA

Upstream 100 bases:

>100_bases
TACCGATACCAGCCCGGGATGATGCGAGGCCCGGGGGCATGGGGCCCGCATCTACCGTTTCGTCGCCGGCCCCGGGCCGG
CCTAGCCATGAGAGGCCCGC

Downstream 100 bases:

>100_bases
CTACCGTATCGACGACGGGATGGAAGTGACCCTGCATTTCACCGTCAAGCTGGAAGATGACACGGTGATCGATTCCACCC
GCGAGAAAGAGGCCGCGACG

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MNDASTSEKIAAAPAMRRPLRWLWLALLVVVLDLGSKFVASAYLVYGQPVEVLPVFNLTLLHNTGAAFSFLAEHAGWQRW
LFAAIAIGVSIGLTVWLTRLKAHERLSAIAIVLVIGGALGNLYDRLVHGYVVDFLSFHWQDYYFPAFNLADTAITLGAMG
LILASLRDDRRNTTQKETPHE

Sequences:

>Translated_181_residues
MNDASTSEKIAAAPAMRRPLRWLWLALLVVVLDLGSKFVASAYLVYGQPVEVLPVFNLTLLHNTGAAFSFLAEHAGWQRW
LFAAIAIGVSIGLTVWLTRLKAHERLSAIAIVLVIGGALGNLYDRLVHGYVVDFLSFHWQDYYFPAFNLADTAITLGAMG
LILASLRDDRRNTTQKETPHE
>Mature_181_residues
MNDASTSEKIAAAPAMRRPLRWLWLALLVVVLDLGSKFVASAYLVYGQPVEVLPVFNLTLLHNTGAAFSFLAEHAGWQRW
LFAAIAIGVSIGLTVWLTRLKAHERLSAIAIVLVIGGALGNLYDRLVHGYVVDFLSFHWQDYYFPAFNLADTAITLGAMG
LILASLRDDRRNTTQKETPHE

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=151, Percent_Identity=51.6556291390728, Blast_Score=155, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 20065; Mature: 20065

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDASTSEKIAAAPAMRRPLRWLWLALLVVVLDLGSKFVASAYLVYGQPVEVLPVFNLTL
CCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEHHHEEE
LHNTGAAFSFLAEHAGWQRWLFAAIAIGVSIGLTVWLTRLKAHERLSAIAIVLVIGGALG
EECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLYDRLVHGYVVDFLSFHWQDYYFPAFNLADTAITLGAMGLILASLRDDRRNTTQKETPH
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
E
C
>Mature Secondary Structure
MNDASTSEKIAAAPAMRRPLRWLWLALLVVVLDLGSKFVASAYLVYGQPVEVLPVFNLTL
CCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEHHHEEE
LHNTGAAFSFLAEHAGWQRWLFAAIAIGVSIGLTVWLTRLKAHERLSAIAIVLVIGGALG
EECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLYDRLVHGYVVDFLSFHWQDYYFPAFNLADTAITLGAMGLILASLRDDRRNTTQKETPH
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA